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SIGLYN M 100/1000 TABLET 10'S
SIGLYN M 100/1000 TABLET 10'S
By ZYDUS LIFESCIENCES LIMITED
MRP
₹
187
₹158.95
15 % OFF
₹15.9 Only /
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Product Details
About SIGLYN M 100/1000 TABLET 10'S
- SIGLYN M 100/1000 is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control in adults when used along with diet and exercise. This medication contains two active ingredients: Sitagliptin and Metformin.
- Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It works by increasing the amount of certain natural substances that lower blood sugar. Sitagliptin helps to increase insulin release, especially after a meal, and decreases the amount of sugar your liver makes.
- Metformin is a biguanide. It works by reducing glucose production in the liver and improving insulin sensitivity, allowing your body to use insulin more effectively. Metformin also helps to decrease the amount of glucose absorbed from your intestines.
- SIGLYN M 100/1000 is typically taken orally once or twice daily with meals to reduce gastrointestinal side effects. Your doctor will determine the appropriate dosage based on your individual needs and response to treatment. It's crucial to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly while taking this medication.
- This medicine is not for use in treating type 1 diabetes. Common side effects of SIGLYN M 100/1000 may include nausea, vomiting, diarrhea, stomach pain, and loss of appetite. If you experience any persistent or severe side effects, consult your doctor. It's also important to inform your doctor about any other medications you are taking, as drug interactions can occur. People with kidney problems should use it with caution.
- Maintain a healthy diet and regular exercise routine while on SIGLYN M 100/1000 for optimal blood sugar control. Regular monitoring of HbA1c is recommended for better outcome.
Uses of SIGLYN M 100/1000 TABLET 10'S
- Treatment of type 2 diabetes mellitus
- Lowering high blood sugar levels
- Improving insulin sensitivity
- Controlling blood sugar levels after meals
- Managing insulin resistance in polycystic ovary syndrome (PCOS) (off-label use)
How SIGLYN M 100/1000 TABLET 10'S Works
- SIGLYN M 100/1000 Tablet is a combination medicine used to treat type 2 diabetes mellitus. It combines two antidiabetic medications: Sitagliptin and Metformin. This combination works through complementary mechanisms to control blood sugar levels effectively.
- Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 inhibitors work by increasing the amount of incretin hormones released by the gut after a meal. Incretin hormones help to stimulate insulin release from the pancreas and decrease the amount of glucagon (a hormone that raises blood sugar) produced by the liver. By increasing insulin and decreasing glucagon, sitagliptin helps lower blood sugar levels, particularly after meals.
- Metformin, on the other hand, is a biguanide. It primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. Specifically, metformin reduces hepatic glucose production by inhibiting gluconeogenesis (the process of creating glucose from non-carbohydrate sources). It also enhances insulin sensitivity in peripheral tissues (muscle and fat), allowing cells to better utilize available glucose. Furthermore, metformin slows down the absorption of glucose from the intestines into the bloodstream.
- The combination of sitagliptin and metformin provides a dual approach to managing blood sugar. Sitagliptin enhances insulin secretion and reduces glucagon, while metformin reduces glucose production and improves insulin sensitivity. This synergistic effect helps to achieve better glycemic control than either medication alone.
- SIGLYN M 100/1000 Tablet is typically prescribed when diet and exercise alone are not sufficient to control blood sugar levels in patients with type 2 diabetes. It's crucial to take this medication as directed by your doctor, usually with meals, to minimize gastrointestinal side effects associated with metformin. Regular monitoring of blood sugar levels and kidney function is also important while taking this medication.
Side Effects of SIGLYN M 100/1000 TABLET 10'S
Possible side effects of SIGLYN M 100/1000 Tablet may include: * **Common Side Effects:** Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Headache, Hypoglycemia (low blood sugar) – symptoms may include sweating, shakiness, anxiety, blurred vision, rapid heartbeat. * **Uncommon Side Effects:** Rash, Itching, Urticaria (hives), Vitamin B12 deficiency (symptoms may include fatigue, weakness, numbness or tingling in hands and feet, sore tongue), Lactic acidosis (rare but serious, symptoms include rapid breathing, stomach pain, feeling cold, irregular heartbeat), Altered taste, Constipation, Flatulence, Dizziness. * **Rare Side Effects:** Liver problems (symptoms may include yellowing of the skin or eyes, dark urine, abdominal pain), Allergic reactions (swelling of the face, lips, tongue, or throat, difficulty breathing).
Safety Advice for SIGLYN M 100/1000 TABLET 10'S

Allergies
AllergiesDo not use SIGLYN M 100/1000 TABLET 10'S if you are allergic to it.
Dosage of SIGLYN M 100/1000 TABLET 10'S
- The recommended dosage of SIGLYN M 100/1000 TABLET 10'S is individualized and depends on several factors, including your blood sugar levels, overall health, other medications you are taking, and how your body responds to the treatment. Your doctor will determine the appropriate dosage for you. Typically, it is taken orally once or twice daily, with meals, to minimize gastrointestinal side effects. It is crucial to follow your doctor's instructions precisely regarding the dosage and timing of administration. Do not crush, chew, or break the tablet; swallow it whole with a glass of water.
- The starting dose is usually one tablet once daily, and it may be gradually increased by your doctor based on your blood glucose monitoring results. Regular monitoring of blood sugar levels is essential to assess the effectiveness of the medication and adjust the dosage accordingly. Never adjust the dosage on your own without consulting your doctor.
- If you miss a dose of SIGLYN M 100/1000 TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
- It's important to maintain a consistent dosing schedule to achieve optimal blood sugar control. Take 'SIGLYN M 100/1000 TABLET 10'S' only as per the prescription by your physician only.
- Long-term use of metformin, one of the active ingredients in SIGLYN M 100/1000 TABLET 10'S, may lead to vitamin B12 deficiency. Your doctor may periodically monitor your vitamin B12 levels and recommend supplementation if needed.
What if I miss my dose of SIGLYN M 100/1000 TABLET 10'S?
- If you miss a dose of SIGLYN M 100/1000 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
How to store SIGLYN M 100/1000 TABLET 10'S?
- Keep SIGLYN M 100/1000MG TAB 1X10 away from the reach of children and pets.
- Store SIGLYN M 100/1000MG TAB 1X10 at room temperature.
Benefits of SIGLYN M 100/1000 TABLET 10'S
- SIGLYN M 100/1000 Tablet 10'S offers a dual-action approach to managing type 2 diabetes, combining the power of Sitagliptin and Metformin to effectively control blood sugar levels. Sitagliptin enhances the incretin system, increasing insulin release and decreasing glucagon secretion, both of which help to lower blood glucose. Metformin, on the other hand, primarily works by reducing glucose production in the liver and improving insulin sensitivity in the body's tissues, allowing for better glucose uptake and utilization.
- One of the key benefits of SIGLYN M 100/1000 is its ability to provide comprehensive glycemic control throughout the day. By targeting multiple pathways involved in glucose regulation, it helps to maintain stable blood sugar levels, reducing the risk of hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). This is particularly important for individuals who struggle to manage their blood sugar with diet and exercise alone.
- SIGLYN M 100/1000 Tablet is also beneficial in reducing the long-term complications associated with diabetes. By keeping blood sugar levels within the target range, it can help to prevent or delay the onset of serious health issues such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems. Managing blood sugar effectively is crucial for preserving overall health and quality of life for individuals with type 2 diabetes.
- Another advantage of this medication is its convenient oral administration. As a tablet, it is easy to take and can be incorporated seamlessly into a daily routine. This can improve adherence to the treatment plan, which is essential for achieving optimal blood sugar control. However, it's important to take the medication as prescribed by your doctor, usually with meals, to minimize potential side effects and maximize its effectiveness.
- Furthermore, SIGLYN M 100/1000 may contribute to weight management in some individuals. Metformin, one of the active ingredients, has been associated with modest weight loss or weight stabilization in some patients. While it is not a weight loss drug, this can be a welcome benefit for individuals with type 2 diabetes who are also trying to manage their weight. Maintaining a healthy weight is an important part of managing diabetes and reducing the risk of complications.
- Finally, SIGLYN M 100/1000 Tablet can improve overall well-being by alleviating the symptoms of uncontrolled diabetes, such as excessive thirst, frequent urination, fatigue, and blurred vision. By effectively managing blood sugar levels, it can help to restore energy levels, improve concentration, and enhance overall quality of life. It is crucial to use this medication under the guidance of a healthcare professional to monitor its effectiveness and manage any potential side effects.
How to use SIGLYN M 100/1000 TABLET 10'S
- SIGLYN M 100/1000 Tablet is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control when used along with diet and exercise. To get the most benefit from SIGLYN M 100/1000 Tablet, it's crucial to follow your doctor's instructions precisely. This includes the prescribed dosage, timing, and duration of treatment. Typically, it is taken orally, usually once or twice daily, along with meals to minimize the risk of stomach upset. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
- Consistency is key with SIGLYN M 100/1000 Tablet. Try to take it at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. It is recommended that you continue following the diet and exercise advice given by your doctor while taking this medicine. Regularly monitor your blood sugar levels as directed by your healthcare provider to track your progress and adjust your treatment plan if needed.
- Inform your doctor about all other medications, supplements, or herbal products you are currently taking to avoid potential drug interactions. Also, let your doctor know if you have any kidney or liver problems before starting SIGLYN M 100/1000 Tablet. Common side effects may include nausea, vomiting, diarrhea, or stomach pain. If these side effects persist or worsen, consult your doctor. It's important to stay hydrated while taking this medication. Long-term use of metformin, one of the components of this medicine, may lead to vitamin B12 deficiency, so your doctor may recommend periodic monitoring of your B12 levels.
Quick Tips for SIGLYN M 100/1000 TABLET 10'S
- Take SIGLYN M 100/1000 Tablet as prescribed by your doctor. It's crucial to follow the dosage and timing instructions to effectively manage your blood sugar levels. Consistency is key for optimal results. Do not alter the dosage without consulting your physician.
- SIGLYN M 100/1000 Tablet is typically taken with meals to minimize potential stomach upset and enhance absorption of the medication. Try to take it at the same time each day to maintain a steady level of the drug in your system, which will contribute to better glucose control throughout the day. Forgetting a dose can impact your glucose levels, so set up reminders if needed.
- Inform your doctor about all other medications, herbal supplements, and vitamins you are taking before starting SIGLYN M 100/1000 Tablet. Certain medications can interact with this drug, potentially altering its effectiveness or increasing the risk of side effects. Be especially mindful of informing your doctor about any heart or kidney issues you may have, as these conditions can influence the suitability of this medication.
- Monitor your blood sugar levels regularly, as directed by your healthcare provider, while taking SIGLYN M 100/1000 Tablet. Keeping a log of your readings can help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. It's also important to be aware of the signs and symptoms of both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar), and know how to respond to them.
- Maintain a healthy lifestyle while taking SIGLYN M 100/1000 Tablet. This includes eating a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. These lifestyle modifications can significantly improve your blood sugar control and reduce your risk of diabetes-related complications. Consider consulting with a registered dietitian or certified diabetes educator to develop a personalized meal plan and exercise regimen that suits your needs.
Food Interactions with SIGLYN M 100/1000 TABLET 10'S
- SIGLYN M 100/1000 TABLET 10'S should be taken with food to decrease the possibility of an upset stomach.
- Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis.
- There are no specific foods to avoid unless otherwise directed by your doctor.
FAQs
What is SIGLYN M 100/1000 Tablet used for?

SIGLYN M 100/1000 Tablet is used to treat type 2 diabetes mellitus. It helps control blood sugar levels when diet and exercise alone are not enough.
How does SIGLYN M 100/1000 Tablet work?

SIGLYN M 100/1000 Tablet is a combination of two medicines, Sitagliptin and Metformin. Sitagliptin works by increasing incretin levels, which increases insulin secretion and decreases glucose production. Metformin works by decreasing glucose production in the liver and improving insulin sensitivity.
What are the common side effects of SIGLYN M 100/1000 Tablet?

Common side effects of SIGLYN M 100/1000 Tablet include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.
Does SIGLYN M 100/1000 Tablet cause weight gain?

No, SIGLYN M 100/1000 Tablet does not typically cause weight gain. In fact, some people may experience weight loss with it.
Can I drink alcohol with SIGLYN M 100/1000 Tablet?

It is not recommended to drink alcohol with SIGLYN M 100/1000 Tablet, as it can increase the risk of lactic acidosis, a serious side effect.
Is SIGLYN M 100/1000 Tablet safe in pregnancy?

The safety of SIGLYN M 100/1000 Tablet in pregnancy has not been established. Therefore, it should only be used during pregnancy if clearly needed and prescribed by a doctor.
Is SIGLYN M 100/1000 Tablet safe for breastfeeding women?

It is not known whether SIGLYN M 100/1000 Tablet is excreted in breast milk. Therefore, breastfeeding women should consult a doctor before using it.
How to store SIGLYN M 100/1000 Tablet?

Store SIGLYN M 100/1000 Tablet at room temperature, away from moisture and heat. Keep it out of reach of children and pets.
What happens if I miss a dose of SIGLYN M 100/1000 Tablet?

If you miss a dose of SIGLYN M 100/1000 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.
Is it safe to take other medications with SIGLYN M 100/1000 Tablet?

It is important to consult a doctor before taking other medications with SIGLYN M 100/1000 Tablet, as some medications can interact with it and cause side effects.
Is SIGLYN M 100/1000 Tablet safe for people with kidney disease?

People with kidney disease should use SIGLYN M 100/1000 Tablet with caution, as it can increase the risk of lactic acidosis. Dosage adjustments or use of an alternative medication may be necessary.
What are other brands of Metformin?

Metformin is available under various brand names such as Glucophage, Glycomet, and Formet.
What are other brands of Sitagliptin?

Sitagliptin is available under various brand names such as Januvia.
Should SIGLYN M 100/1000 Tablet be taken with or without food?

SIGLYN M 100/1000 Tablet is generally recommended to be taken with food to minimize the chance of stomach upset.
What to do in case of an overdose of SIGLYN M 100/1000 Tablet?

In case of an overdose of SIGLYN M 100/1000 Tablet, contact a doctor immediately or go to the nearest hospital.
Ratings & Review
Very good service and discount
Yatin Patel
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Reviewed on 13-01-2024
(5/5)
Good. Provides medicines at reasonable rates.
Jiji Varughese
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Reviewed on 08-02-2024
(4/5)
Best pharmacy for all type medicine specialy for generic medicine
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Reviewed on 13-01-2024
(5/5)
Good services, rates are competitive!
Geetika Purohit
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Reviewed on 16-01-2024
(5/5)
Jenerik medicines is best than regular branded medicines. Extra ordinary benefit against branded medicines. I have saved more than 80% against branded medicines.
Naresh Shah
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Reviewed on 06-01-2024
(5/5)
Marketer / Manufacturer Details
ZYDUS LIFESCIENCES LIMITED
Country of Origin -
India
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