SITARED M 50MG/500MG TABLET 15'S

How SITARED M 50MG/500MG TABLET 15'S Works

• SITARED M 50MG/500MG TABLET 15'S is a combination medication containing Sitagliptin (50mg) and Metformin (500mg), designed to manage blood sugar levels in adults with type 2 diabetes mellitus. It works through complementary mechanisms of action to achieve better glycemic control than either medicine could alone. Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors), and Metformin is a biguanide.
• Sitagliptin enhances the incretin system. Incretins are hormones released by the gut in response to food intake. These hormones stimulate the release of insulin from the pancreas and reduce the secretion of glucagon, a hormone that raises blood sugar. Sitagliptin inhibits the DPP-4 enzyme, which normally inactivates incretins. By inhibiting DPP-4, Sitagliptin increases the levels of active incretins in the body. This leads to increased insulin release when blood sugar is high (after a meal) and decreased glucagon secretion, both of which help lower blood sugar levels. Sitagliptin's action is glucose-dependent, meaning it primarily works when blood sugar is elevated, reducing the risk of hypoglycemia (low blood sugar).
• Metformin, on the other hand, primarily works by decreasing glucose production in the liver. The liver is a major source of glucose in the body, and in type 2 diabetes, the liver often produces excessive amounts of glucose. Metformin reduces hepatic glucose production by inhibiting gluconeogenesis (the process by which the liver makes glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to use glucose more effectively. It also slows down the absorption of glucose from the intestines into the bloodstream, further contributing to its blood sugar-lowering effects. Unlike some other diabetes medications, Metformin does not stimulate insulin release and therefore carries a low risk of causing hypoglycemia when used alone.
• In combination, Sitagliptin and Metformin provide a synergistic effect. Sitagliptin enhances insulin secretion and reduces glucagon levels in a glucose-dependent manner, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This dual action effectively targets multiple pathways involved in blood sugar control. Patients taking SITARED M 50MG/500MG TABLET 15'S typically experience improved blood sugar levels throughout the day, especially after meals. Regular monitoring of blood sugar levels, adherence to a healthy diet, and regular exercise are important components of diabetes management while taking this medication.

Common side effects of SITARED M 50MG/500MG Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and headache. Some patients may also experience hypoglycemia (low blood sugar), especially when taken with other diabetes medications. Less common but potentially serious side effects can include pancreatitis, severe allergic reactions (rash, itching, swelling), lactic acidosis (symptoms include muscle cramps, rapid breathing, and stomach pain), and liver problems. It's crucial to contact your doctor immediately if you experience any persistent or severe side effects.

• If you miss a dose of SITARED M 50MG/500MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep SITARED M 50/500MG TAB 1X15 away from the reach of children and pets.
• Store SITARED M 50/500MG TAB 1X15 at room temperature.

• Take SITARED M 50MG/500MG TABLET 15'S as prescribed by your doctor, usually once or twice daily with meals. This helps to minimize stomach upset and ensures consistent absorption of the medication.
• It is crucial to maintain a consistent diet and exercise routine while taking SITARED M 50MG/500MG TABLET 15'S. Focus on whole grains, lean proteins, and plenty of fruits and vegetables, and engage in at least 30 minutes of moderate-intensity exercise most days of the week to enhance the medication's effectiveness and manage your blood sugar levels effectively.
• Regularly monitor your blood sugar levels as directed by your healthcare provider. Keeping a log of your readings will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Aim for target blood sugar ranges advised by your doctor.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as shakiness, sweating, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times to quickly treat low blood sugar. Inform your family and friends about recognizing and treating hypoglycemia.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. Some medications can interact with SITARED M 50MG/500MG TABLET 15'S, potentially affecting its efficacy or increasing the risk of side effects. Do not start or stop any medications without consulting your doctor.
• Stay well-hydrated by drinking plenty of water throughout the day, unless your doctor advises otherwise due to certain medical conditions. Proper hydration supports overall health and helps your body process medications efficiently. Aim for at least 8 glasses of water daily.
• Attend all scheduled appointments with your doctor and undergo regular check-ups, including blood tests and kidney function tests. These appointments are essential for monitoring your overall health and assessing the effectiveness of your diabetes management plan. Early detection of any potential issues can prevent complications.

• SITARED M 50MG/500MG TABLET 15'S can be taken with or without food, but it is generally recommended to take it with meals to reduce the risk of stomach upset.
• Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of side effects such as hypoglycemia (low blood sugar) and lactic acidosis.