SYNAPTOL SR 450MG TABLET 10'S

How SYNAPTOL SR 450MG TABLET 10'S Works

• SYNAPTOL SR 450MG Tablet contains Oxcarbazepine, an antiepileptic medication that effectively manages seizures by stabilizing neuronal membranes and inhibiting repetitive neuronal firing. This is achieved through the blockade of voltage-sensitive sodium channels. These channels are crucial for the generation and propagation of action potentials in neurons. When Oxcarbazepine blocks these channels, it reduces the excitability of neurons, making them less likely to fire excessively and cause seizures. Specifically, Oxcarbazepine prolongs the inactivated state of sodium channels, preventing them from rapidly returning to their active state, thus damping neuronal hyperactivity.
• The sustained-release (SR) formulation of SYNAPTOL SR ensures a gradual release of the medication into the bloodstream. This slow and controlled release mechanism helps maintain a stable concentration of the drug in the body over an extended period. This reduces the fluctuations in drug levels, minimizing the risk of breakthrough seizures that can occur with immediate-release formulations. Furthermore, the consistent drug levels provided by the SR formulation can also decrease the incidence of side effects associated with peak concentrations of the drug.
• Once Oxcarbazepine is absorbed, it is rapidly metabolized to its active metabolite, Monohydroxycarbazepine (MHD). MHD is primarily responsible for the antiepileptic effect. MHD also modulates the sodium channels, contributing to the overall reduction in neuronal excitability. Both Oxcarbazepine and MHD do not enhance GABAergic neurotransmission or directly bind to glutamate receptors, distinguishing their mechanism of action from other antiepileptic drugs. This specific action on sodium channels allows for effective seizure control while minimizing interaction with other neurotransmitter systems.
• In summary, SYNAPTOL SR 450MG Tablet works by blocking voltage-sensitive sodium channels, stabilizing neuronal membranes, and preventing repetitive neuronal firing. The sustained-release formulation ensures stable drug levels, reducing seizure risk and side effects. The active metabolite, MHD, further enhances the antiepileptic effect. This targeted mechanism of action makes SYNAPTOL SR an effective option for managing seizures in individuals with epilepsy.

Common side effects of Synaptol SR 450mg Tablet may include nausea, vomiting, diarrhea, constipation, stomach pain, loss of appetite, headache, dizziness, drowsiness, weakness, dry mouth, blurred vision, and difficulty sleeping. Less common but potentially serious side effects can include allergic reactions (rash, itching, swelling), liver problems (yellowing of skin/eyes, dark urine, abdominal pain), changes in mood or behavior (depression, anxiety, agitation), seizures, and irregular heartbeat. If you experience any persistent or severe side effects, or any signs of an allergic reaction, seek immediate medical attention.

• If you miss a dose of SYNAPTOL SR 450MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep SYNAPTOL SR 450MG TAB 1X10 away from the reach of children and pets.
• Store SYNAPTOL SR 450MG TAB 1X10 at room temperature.

• Take SYNAPTOL SR 450MG TABLET 10'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet. Swallow it whole with a full glass of water. This medication is designed for slow release, and altering the tablet can affect how the medicine is absorbed into your system, potentially leading to adverse effects or reduced efficacy.
• To minimize stomach upset, take SYNAPTOL SR 450MG TABLET 10'S with food. Consistent timing helps maintain a steady level of medication in your bloodstream. Try to take it at the same time each day. If you experience nausea or other gastrointestinal issues, consult your healthcare provider.
• Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking before starting SYNAPTOL SR 450MG TABLET 10'S. Certain medications can interact with this drug, altering its effectiveness or increasing the risk of side effects. This includes over-the-counter drugs and even certain foods or beverages.
• Be aware of potential side effects while taking SYNAPTOL SR 450MG TABLET 10'S. Common side effects include dizziness, drowsiness, and nausea. If these side effects are persistent or severe, contact your doctor. Also, watch out for any signs of allergic reactions, such as rash, itching, swelling, or difficulty breathing, and seek immediate medical attention if they occur.
• Do not abruptly stop taking SYNAPTOL SR 450MG TABLET 10'S without consulting your doctor. Stopping the medication suddenly can lead to withdrawal symptoms or a worsening of your condition. Your doctor will gradually reduce the dosage if it is necessary to discontinue the treatment. Follow their instructions carefully for a safe and effective transition.

• There are no specific food interactions known for SYNAPTOL SR 450MG TABLET. It can be taken with or without food. However, it is advisable to take it at the same time each day to maintain consistent blood levels of the medication.