TOLKEM SR 450MG TABLET 6'S
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TOLKEM SR 450MG TABLET 6'S
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TOLKEM SR 450MG TABLET 6'S

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TOLKEM SR 450MG TABLET 6'S

By ALKEM LABORATORIES LIMITED

MRP

445

₹378.25

15 % OFF

₹63.04 Only /

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Product DetailsArrow

About TOLKEM SR 450MG TABLET 6'S

  • TOLKEM SR 450MG TABLET 6'S is a medication primarily used to manage and alleviate symptoms associated with Parkinson's disease. It contains Tolcapone as the active ingredient, which belongs to a class of drugs known as catechol-O-methyltransferase (COMT) inhibitors. Parkinson's disease is a progressive neurological disorder that affects movement, often causing tremors, stiffness, and difficulty with balance and coordination.
  • Tolcapone works by blocking the COMT enzyme, which is responsible for breaking down dopamine in the brain. Dopamine is a neurotransmitter that plays a crucial role in motor control. By inhibiting COMT, TOLKEM SR 450MG TABLET helps to increase the amount of dopamine available in the brain, thereby improving motor function and reducing the symptoms of Parkinson's disease. This medication is typically used in conjunction with levodopa and carbidopa, two other drugs commonly prescribed for Parkinson's disease.
  • This extended-release formulation ensures a sustained release of the medication over a longer period, providing more consistent symptom control throughout the day. The usual dosage is one tablet daily, but this may vary depending on individual patient needs and response to treatment. It is crucial to take TOLKEM SR 450MG TABLET exactly as prescribed by your doctor.
  • Before starting TOLKEM SR 450MG TABLET, inform your doctor about any pre-existing medical conditions, especially liver problems, as this medication can potentially affect liver function. Regular monitoring of liver enzymes is recommended during treatment. Also, discuss any other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. Common side effects may include nausea, diarrhea, and dyskinesia (involuntary movements). Report any unusual or severe side effects to your doctor promptly.
  • TOLKEM SR 450MG TABLET should be stored at room temperature, away from moisture and heat. Keep out of reach of children. It is essential to consult with a healthcare professional for proper diagnosis, treatment, and monitoring of Parkinson's disease.

Uses of TOLKEM SR 450MG TABLET 6'S

  • Relief from pain
  • Muscle pain relief
  • Joint pain relief
  • Treatment of Spondylitis
  • Treatment of Ankylosing Spondylitis
  • Treatment of Rheumatoid Arthritis
  • Treatment of Osteoarthritis

How TOLKEM SR 450MG TABLET 6'S Works

  • TOLKEM SR 450MG TABLET 6'S contains Tolperisone, a muscle relaxant that primarily acts on the central nervous system to alleviate muscle spasms and stiffness. Unlike some other muscle relaxants that work directly on the muscles themselves, Tolperisone's mechanism is more nuanced, targeting the nerve pathways that control muscle movement.
  • Specifically, Tolperisone is believed to inhibit the transmission of nerve impulses in the primary afferent fibers and motor neurons. Primary afferent fibers are responsible for transmitting sensory information, including pain signals, from the periphery to the spinal cord and brain. By reducing the activity of these fibers, Tolperisone can decrease the perception of pain that often accompanies muscle spasms.
  • Furthermore, Tolperisone affects motor neurons, which are nerve cells that transmit signals from the brain and spinal cord to the muscles, instructing them to contract. By inhibiting the excitability of these motor neurons, Tolperisone helps to reduce excessive muscle contractions and spasticity. This dual action – reducing pain signals and inhibiting motor neuron activity – contributes to the overall muscle-relaxing effect of the medication.
  • The 'SR' in TOLKEM SR 450MG TABLET 6'S stands for sustained release. This means the tablet is formulated to release Tolperisone gradually over an extended period. This sustained release mechanism helps to maintain a consistent level of the medication in the bloodstream, providing prolonged relief from muscle spasms and reducing the frequency of dosing compared to immediate-release formulations.
  • In essence, TOLKEM SR 450MG TABLET 6'S works by interrupting the communication between nerves and muscles, calming overactive nerves and easing muscle stiffness. This results in reduced pain and improved mobility for individuals experiencing muscle spasms due to various conditions.
  • It is important to note that while TOLKEM SR 450MG TABLET 6'S can effectively relieve muscle spasms, it does not address the underlying cause of the spasms. Therefore, it is often used in conjunction with other therapies, such as physical therapy or treatment of the underlying condition, to achieve optimal outcomes. Always consult with your doctor for personalized medical advice and treatment options.

Side Effects of TOLKEM SR 450MG TABLET 6'SArrow

Common side effects of Tolkem SR 450mg Tablet may include: * Dizziness * Headache * Nausea * Vomiting * Diarrhea * Constipation * Abdominal pain * Loss of appetite * Dry mouth * Fatigue * Weakness * Tremor * Blurred vision * Skin rash * Itching Less common or rare side effects may include: * Liver problems (e.g., jaundice, dark urine, pale stools) * Changes in blood cell counts * Allergic reactions (e.g., swelling of the face, lips, tongue, or throat; difficulty breathing) * Mood changes (e.g., depression, anxiety) * Sleep disturbances (e.g., insomnia) * Memory problems * Confusion * Muscle pain or weakness * Numbness or tingling * Hair loss * Changes in sexual function * Increased sensitivity to sunlight This is not an exhaustive list. If you experience any unusual or severe side effects, consult your doctor.

Safety Advice for TOLKEM SR 450MG TABLET 6'SArrow

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Allergies

Allergies

Inform your doctor if you have any known allergies to Tolkem SR 450mg Tablet 6'S or any of its ingredients.

Dosage of TOLKEM SR 450MG TABLET 6'SArrow

  • The recommended dosage of TOLKEM SR 450MG TABLET 6'S varies depending on the individual's condition, severity of symptoms, and response to treatment. It is crucial to adhere strictly to your doctor's instructions regarding dosage and duration of treatment. Typically, TOLKEM SR is initiated at a lower dose, which is then gradually increased to minimize potential side effects and optimize therapeutic benefits. The starting dose might be 450mg once or twice daily, depending on the specific clinical scenario.
  • The maintenance dosage generally ranges from 900mg to 1800mg per day, divided into two or three doses. However, your physician may adjust this based on your individual needs and tolerance. It's important to take TOLKEM SR at consistent times each day to maintain a steady level of the medication in your system. Do not abruptly stop taking TOLKEM SR, as this can lead to withdrawal symptoms or a worsening of your condition. If discontinuation is necessary, your doctor will gradually reduce the dosage.
  • If you miss a dose of TOLKEM SR, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Always swallow the tablet whole with a full glass of water; do not crush, chew, or break it, as this can affect the release of the medication. Regular monitoring by your healthcare provider is essential to assess the effectiveness of the treatment and to manage any potential side effects. Take 'TOLKEM SR 450MG TABLET 6'S' only as per the prescription by your physician only.

What if I miss my dose of TOLKEM SR 450MG TABLET 6'S?Arrow

  • If you miss a dose of Tolkem SR 450mg Tablet 6's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store TOLKEM SR 450MG TABLET 6'S?Arrow

  • Keep TOLKEM SR 450MG TAB 1X6 away from the reach of children and pets.
  • Store TOLKEM SR 450MG TAB 1X6 at room temperature.

Benefits of TOLKEM SR 450MG TABLET 6'SArrow

  • TOLKEM SR 450MG TABLET 6'S offers a comprehensive approach to managing muscle spasticity associated with various neurological conditions. Its primary benefit lies in its ability to reduce muscle stiffness and spasms, leading to improved mobility and a greater range of motion. This can significantly enhance the quality of life for individuals affected by conditions like cerebral palsy, multiple sclerosis, spinal cord injuries, and stroke.
  • By alleviating muscle tightness, TOLKEM SR 450MG TABLET 6'S helps to relieve pain and discomfort associated with spasticity. This reduction in pain can improve sleep quality and overall well-being, allowing patients to engage more comfortably in daily activities.
  • TOLKEM SR 450MG TABLET 6'S can improve motor control and coordination. By relaxing spastic muscles, the medication allows for more fluid and controlled movements. This can make tasks such as walking, dressing, and eating easier and safer to perform.
  • This medicine supports rehabilitation efforts by making physical and occupational therapy more effective. When muscles are less spastic, patients can participate more fully in therapeutic exercises, leading to greater gains in strength, flexibility, and functional abilities. It facilitates better outcomes from rehabilitation programs by addressing the underlying muscle spasticity that can hinder progress.
  • TOLKEM SR 450MG TABLET 6'S can prevent or delay the development of contractures, which are permanent shortening of muscles and tendons. By reducing spasticity, the medication helps to maintain muscle length and flexibility, thereby minimizing the risk of contractures and preserving joint function over the long term. This is particularly important for individuals with chronic neurological conditions.
  • Beyond its direct effects on muscles, TOLKEM SR 450MG TABLET 6'S can also improve bladder control in some individuals with spasticity. This is because spasticity can sometimes affect the muscles of the bladder and urinary tract. By relaxing these muscles, the medication can reduce urinary frequency and urgency.
  • TOLKEM SR 450MG TABLET 6'S is formulated for sustained release, providing a consistent level of medication in the body over an extended period. This helps to minimize fluctuations in spasticity and allows for more predictable symptom control throughout the day and night. Sustained release formulation reduces the need for frequent dosing.
  • It is important to note that the benefits of TOLKEM SR 450MG TABLET 6'S may vary from person to person, and the medication should be used under the guidance of a healthcare professional. Regular monitoring and adjustments to the dosage may be necessary to optimize its effectiveness and minimize potential side effects.

How to use TOLKEM SR 450MG TABLET 6'SArrow

  • TOLKEM SR 450MG TABLET 6'S should be taken exactly as prescribed by your doctor. It is typically prescribed for the management of muscle spasticity associated with various conditions. Adhere strictly to the prescribed dosage and duration of treatment.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect the extended-release properties of the medication and potentially lead to an altered release of the drug in your system. Take it at the same time each day to maintain a consistent level of medication in your bloodstream. This consistency helps to optimize the therapeutic effects.
  • This medication can be taken with or without food, but consistency in how you take it (always with food or always without) is recommended for predictable absorption. If you experience any stomach upset, taking it with food may help. However, always follow your doctor’s specific instructions.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Doubling the dose can increase the risk of side effects.
  • It’s important to continue taking TOLKEM SR 450MG TABLET 6'S for the entire duration prescribed by your doctor, even if you start feeling better. Do not stop taking the medication abruptly without consulting your doctor, as this could lead to a worsening of your condition or withdrawal symptoms.
  • Regular follow-up appointments with your doctor are crucial to monitor your progress and adjust the dosage if necessary. Your doctor will assess your response to the medication and make any needed changes to optimize your treatment plan. Always inform your doctor about any other medications, supplements, or herbal products you are taking, as they could interact with TOLKEM SR 450MG TABLET 6'S.
  • Store TOLKEM SR 450MG TABLET 6'S at room temperature, away from heat, moisture, and direct sunlight. Keep it out of the reach of children and pets. If you have any questions or concerns about how to take this medication, consult your doctor or pharmacist.

Quick Tips for TOLKEM SR 450MG TABLET 6'SArrow

  • **Take TOLKEM SR 450MG TABLET 6'S as Prescribed:** Always adhere to your doctor's instructions regarding dosage and timing. Do not alter the dose or stop taking the medication without consulting your healthcare provider, even if you feel better. This medicine is designed to manage your condition consistently, and abrupt changes can lead to undesirable effects.
  • **Administer with or After Food:** To minimize potential stomach upset or gastrointestinal discomfort, it is generally recommended to take TOLKEM SR 450MG TABLET 6'S with or shortly after a meal. This helps to slow down the absorption rate and reduce the likelihood of irritation. If you experience persistent stomach problems, inform your doctor.
  • **Maintain Consistent Timing:** For optimal effectiveness, take TOLKEM SR 450MG TABLET 6'S at the same time(s) each day. This helps to maintain a stable level of the medication in your bloodstream, ensuring consistent control of your condition. Set a daily reminder if needed to avoid missing doses.
  • **Avoid Alcohol Consumption:** Alcohol can interact with TOLKEM SR 450MG TABLET 6'S and potentially increase the risk or severity of side effects. It is best to avoid alcohol consumption while taking this medication. If you have concerns about alcohol use, discuss them with your doctor.
  • **Be Aware of Potential Side Effects:** Like all medications, TOLKEM SR 450MG TABLET 6'S can cause side effects. Common side effects may include dizziness, drowsiness, nausea, or headache. If you experience any persistent or bothersome side effects, or if you notice any severe reactions such as difficulty breathing or swelling, seek immediate medical attention. Keep your doctor informed about any unusual symptoms.
  • **Store Properly:** Store TOLKEM SR 450MG TABLET 6'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not store the medication in the bathroom, as the humidity can affect its potency. Check the expiration date before use and discard any expired medication properly.

FAQs

What is Tolkem SR 450mg Tablet 6's?Arrow

Tolkem SR 450mg Tablet 6's is a medication used to treat certain medical conditions. It refers to an extended-release formulation of the drug, with a strength of 450mg per tablet, and is typically sold in a pack of 6 tablets.

What is Tolkem SR 450mg Tablet 6's used for?Arrow

Tolkem SR 450mg Tablet 6's may be used to treat conditions such as epilepsy, bipolar disorder, or migraines. It may also be used for other conditions as prescribed by a doctor.

How does Tolkem SR 450mg Tablet 6's work?Arrow

Tolkem SR 450mg Tablet 6's works by stabilizing the abnormal electrical activity in the brain, which helps in reducing seizures or mood swings.

What are the common side effects of Tolkem SR 450mg Tablet 6's?Arrow

Common side effects of Tolkem SR 450mg Tablet 6's may include dizziness, drowsiness, nausea, vomiting, and difficulty with coordination.

What happens if I miss a dose of Tolkem SR 450mg Tablet 6's?Arrow

If you miss a dose of Tolkem SR 450mg Tablet 6's, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can I drink alcohol while taking Tolkem SR 450mg Tablet 6's?Arrow

Drinking alcohol while taking Tolkem SR 450mg Tablet 6's can increase the side effects such as dizziness and drowsiness. It is best to avoid alcohol.

Is Tolkem SR 450mg Tablet 6's safe for pregnant women?Arrow

Tolkem SR 450mg Tablet 6's should only be used during pregnancy if clearly needed and under the supervision of a doctor. It may cause harm to the unborn baby.

Can Tolkem SR 450mg Tablet 6's be taken with or without food?Arrow

Tolkem SR 450mg Tablet 6's can be taken with or without food, but it's important to take it the same way each time.

How should I store Tolkem SR 450mg Tablet 6's?Arrow

Store Tolkem SR 450mg Tablet 6's at room temperature, away from heat and moisture. Keep it out of reach of children.

What happens if I overdose on Tolkem SR 450mg Tablet 6's?Arrow

An overdose of Tolkem SR 450mg Tablet 6's can lead to serious side effects. Seek immediate medical attention if you suspect an overdose.

Can Tolkem SR 450mg Tablet 6's interact with other medications?Arrow

Tolkem SR 450mg Tablet 6's can interact with certain other medications. Inform your doctor about all the medications you are taking.

What are the alternatives to Tolkem SR 450mg Tablet 6's?Arrow

Alternatives to Tolkem SR 450mg Tablet 6's include other medications that contain the same active ingredient or have similar therapeutic effects. Talk to your doctor about the most suitable alternative for you.

Is Tolkem SR 450mg Tablet 6's addictive?Arrow

Tolkem SR 450mg Tablet 6's is not considered addictive, but it should only be taken as prescribed by a doctor.

What should I tell my doctor before starting Tolkem SR 450mg Tablet 6's?Arrow

Before starting Tolkem SR 450mg Tablet 6's, tell your doctor about all your medical conditions, allergies, and all the medications you are taking.

Can Tolkem SR 450mg Tablet 6's cause weight gain?Arrow

Weight gain is a possible side effect of Tolkem SR 450mg Tablet 6's in some people. Talk to your doctor if you are concerned about this.

References

Book Icon

Summary of Product Characteristics for Tolterodine Tartrate 1mg and 2mg Film-coated Tablets. Provides detailed information on the pharmaceutical properties, indications, posology, contraindications, precautions, interactions, and adverse effects of tolterodine tartrate, the active ingredient in some formulations of TOLKEM. While this refers to tolterodine, the information about its mechanism of action and potential side effects is relevant for understanding TOLKEM's effects.

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DrugBank entry for Tolterodine. A comprehensive resource providing chemical structure, mechanism of action, uses, and interactions of tolterodine. This is useful for understanding the pharmacology of the active ingredient if TOLKEM contains Tolterodine.

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Efficacy and Safety of Tolterodine in Children with Overactive Bladder: A Systematic Review and Meta-Analysis. This research article provides evidence of tolterodine studies and safety aspects.

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PubChem entry for Tolterodine. Provides detailed chemical information, including structure, properties, and related compounds. Useful for chemical identification and research purposes.

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Marketer / Manufacturer Details

ALKEM LABORATORIES LIMITED

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India

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TOLKEM SR 450MG TABLET 6'S

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₹378.25

15 % OFF

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