THIODOC ET TABLET 10'S

How THIODOC ET TABLET 10'S Works

• THIODOC ET Tablet is a combination medication designed to alleviate pain and inflammation associated with musculoskeletal conditions. It contains two active ingredients: etoricoxib and thiocolchicoside. Each component works through a different mechanism to provide synergistic relief.
• Etoricoxib belongs to a class of drugs known as selective cyclooxygenase-2 (COX-2) inhibitors. COX-2 is an enzyme responsible for producing prostaglandins, which are substances that contribute to pain, inflammation, and fever. By selectively inhibiting COX-2, etoricoxib reduces the production of prostaglandins at the site of inflammation. This targeted action helps to alleviate pain and reduce swelling with potentially fewer gastrointestinal side effects compared to non-selective NSAIDs (non-steroidal anti-inflammatory drugs). The reduced prostaglandin production translates to decreased sensitivity of pain receptors and a blunted inflammatory response.
• Thiocolchicoside, on the other hand, is a muscle relaxant. It works by acting on the gamma-aminobutyric acid (GABA) receptors in the central nervous system. GABA is an inhibitory neurotransmitter, meaning it helps to calm down nerve activity. Thiocolchicoside is believed to enhance GABAergic inhibition, which reduces muscle spasms and promotes muscle relaxation. It's also proposed to have some anti-inflammatory and analgesic (pain-relieving) effects through other mechanisms, contributing to its overall therapeutic benefit. Essentially, it helps break the cycle of pain and muscle spasm, allowing for improved mobility and reduced discomfort.
• In summary, THIODOC ET Tablet provides comprehensive relief by addressing both the inflammatory component of pain and the associated muscle spasms. Etoricoxib targets the source of inflammation by inhibiting COX-2, thereby reducing prostaglandin production. Thiocolchicoside acts as a muscle relaxant, reducing muscle spasms by working on GABA receptors in the central nervous system. The combination of these two drugs provides a synergistic effect, offering effective pain relief and improved muscle relaxation compared to using either medication alone. This allows for a more comfortable and functional recovery for patients suffering from musculoskeletal pain and stiffness.

Common side effects of THIODOC ET Tablet may include nausea, vomiting, stomach pain, heartburn, loss of appetite, diarrhea, constipation, drowsiness, dizziness, headache, and skin rash. Less common but potentially serious side effects can include allergic reactions (such as swelling of the face, lips, or tongue; difficulty breathing), liver problems (such as jaundice, dark urine, persistent fatigue), kidney problems (such as changes in urine output, swelling of ankles/feet), gastrointestinal bleeding (such as black, tarry stools; bloody vomit), and cardiovascular issues (such as chest pain, irregular heartbeat). Muscle weakness or pain can also occur. This is not an exhaustive list, and other side effects may occur. Consult your doctor if you experience any unusual or bothersome symptoms while taking THIODOC ET Tablet.

• If you miss a dose of Thiodoc ET Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep THIODOC ET TAB 1X10 away from the reach of children and pets.
• Store THIODOC ET TAB 1X10 at room temperature.

• While taking THIODOC ET TABLET 10'S, there are no specific food restrictions. It can be taken with or without food. However, if you experience any stomach upset, taking it with food may help.