TOFE 10MG TABLET 10'S
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TOFE 10MG TABLET 10'S
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TOFE 10MG TABLET 10'S

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TOFE 10MG TABLET 10'S

By ALKEM LABORATORIES LIMITED

MRP

402.19

₹341.86

15 % OFF

₹34.19 Only /

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About TOFE 10MG TABLET 10'S

  • TOFE 10MG TABLET 10'S contains tofacitinib as its active ingredient. It belongs to a class of drugs called disease-modifying anti-rheumatic drugs (DMARDs), specifically immunomodulators. This medication is prescribed, either alone or in combination with other drugs, for the treatment of rheumatoid arthritis in adults who haven't responded well to other treatments or are unable to take them. Rheumatoid arthritis is an autoimmune condition where the body's immune system mistakenly attacks the joints, leading to pain, swelling, and impaired function. It is also indicated for treating psoriatic arthritis, a condition characterized by joint pain and swelling accompanied by skin scales. TOFE 10MG TABLET 10'S is further used in treating adult patients suffering from moderately to severely active ulcerative colitis, a chronic inflammatory bowel disease affecting the colon.
  • Furthermore, TOFE 10MG TABLET 10'S has applications in managing ankylosing spondylitis, a type of inflammatory disease affecting the spine. It's also utilized in treating active polyarticular juvenile idiopathic arthritis, a chronic condition predominantly causing pain and swelling in the joints of patients aged 2 years and older. Tofacitinib functions by modulating the immune system, reducing its activity to alleviate inflammation and prevent further joint damage. It's crucial to inform your doctor if you have a severe blood infection, active tuberculosis, or any liver problems before starting this medication. Additionally, notify your doctor if you have a history of hepatitis B infection, as this medicine could potentially reactivate the virus.
  • Before taking TOFE 10MG TABLET 10'S, make sure to inform your doctor if you are allergic to tofacitinib or any other ingredients in the medicine. If you experience any signs of infection, such as fever, sweating, chills, muscle aches, cough, shortness of breath, weight loss, skin sores, difficulty swallowing, diarrhea, or stomach pain, promptly inform your healthcare provider. Before starting treatment with this medicine, disclose to your doctor if you have any existing kidney, heart, lung, or liver issues, a past history of tuberculosis, high blood pressure, or high cholesterol levels. Also, inform them if you are a current smoker or have a history of smoking. This information is essential for your doctor to assess the suitability and safety of the treatment for you.

Uses of TOFE 10MG TABLET 10'S

  • Rheumatoid arthritis, a chronic inflammatory disorder affecting many joints, causing pain, swelling, and stiffness.
  • Psoriatic arthritis, a type of arthritis that affects people with psoriasis, causing joint pain, stiffness, and swelling, along with skin symptoms.
  • Ankylosing spondylitis, an inflammatory disease that, over time, can cause some of the vertebrae in your spine to fuse, leading to chronic pain and stiffness.
  • Ulcerative colitis, an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in your digestive tract.
  • Polyarticular juvenile idiopathic arthritis, a type of arthritis that affects multiple joints in children, causing pain, swelling, and stiffness.
  • Juvenile psoriatic arthritis, a type of arthritis that affects children who have psoriasis or a family history of psoriasis, leading to joint pain, swelling, and stiffness.

Side Effects of TOFE 10MG TABLET 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Increased cholesterol levels
  • Headache
  • Painful urination
  • Inflammation of the nose
  • Cough
  • Shortness of breath
  • Diarrhea
  • Skin rashes
  • Lung cancer
  • White blood cell cancer
  • Heart attack
  • Fever and chills
  • Blood in the stool
  • Stomach pain or abdominal pain
  • Skin blisters

Safety Advice for TOFE 10MG TABLET 10'SArrow

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Pregnancy

UNSAFE

TOFE 10MG TABLET 10'S is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 4 weeks after your last dose is necessary.

Dosage of TOFE 10MG TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with TOFE 10MG TABLET 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to adhere strictly to your doctor's instructions regarding the use of this medication.
  • Always take TOFE 10MG TABLET 10'S exactly as prescribed. Do not alter the dosage or frequency of administration without consulting your physician. Doing so may affect the effectiveness of the treatment or increase the risk of side effects.
  • These tablets should be swallowed whole with a full glass of water. Avoid breaking, crushing, or chewing them, as this could interfere with the way the medication is released into your system. The tablets can be taken either with or without food, but maintaining a consistent routine can help you remember to take your dose regularly.

How to store TOFE 10MG TABLET 10'S?Arrow

  • Keep TOFE 10MG TAB 1X10 away from the reach of children and pets.
  • Store TOFE 10MG TAB 1X10 at room temperature.

Benefits of TOFE 10MG TABLET 10'SArrow

  • TOFE 10MG TABLET 10'S is classified as a disease-modifying anti-rheumatic drug (DMARD) and belongs to the Janus Kinase Inhibitors category. This medication plays a crucial role in managing autoimmune conditions by targeting specific enzymes within the body.
  • Janus kinases are enzymes, specifically tyrosine kinases, that participate in cytokine receptor signaling pathways. Cytokines are signaling molecules that regulate immune responses and inflammation. By inhibiting Janus kinases, TOFE 10MG TABLET 10'S effectively modulates these signaling pathways.
  • TOFE 10MG TABLET 10'S interferes with the transcription of genes responsible for cell growth and differentiation. This action helps to control the overactive immune response seen in autoimmune diseases, thereby reducing inflammation and preventing further joint damage.
  • The mechanism of action of TOFE 10MG TABLET 10'S makes it effective in treating conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. By targeting the underlying inflammatory pathways, it helps to alleviate symptoms and improve the overall quality of life for patients.

How to use TOFE 10MG TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other relevant individual factors. It is crucial to adhere strictly to your doctor's prescribed instructions regarding the intake of TOFE 10MG TABLET 10'S.
  • Avoid altering the tablet in any way before consumption. Do not break, crush, or chew the tablets. These tablets are designed to be swallowed whole to ensure proper release of the medication within your system. Doing so might affect the way the medication works.
  • For optimal absorption and effectiveness, swallow the tablet whole with a full glass of water. This aids in the tablet's journey down your esophagus and into your stomach, where it can dissolve properly.
  • TOFE 10MG TABLET 10'S can be taken either with or without food, as directed by your healthcare provider. If you experience any stomach upset, taking it with food might be beneficial. However, always follow your doctor's specific recommendations.

FAQs

What are the cautions of TOFE 10MG TABLET 10'S?Arrow

Tell your doctor immediately if you start to have swelling of your face, lips, tongue, throat, arms, or legs or if you are having trouble swallowing or breathing. TOFE 10MG TABLET 10'S can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection.

Does TOFE 10MG TABLET 10'S cause high cholesterol?Arrow

Increased cholesterol levels are one of the side effects of TOFE 10MG TABLET 10'S, your doctor may take regular blood tests to check for serious side effects.

Can TOFE 10MG TABLET 10'S cause depression?Arrow

No, TOFE 10MG TABLET 10'S does not cause depression. However, many people who have autoimmune conditions also have symptoms of depression. If you're having symptoms of depression, see your doctor right away.

Does TOFE 10MG TABLET 10'S cause blood clots?Arrow

Yes, blood clots are reported in patients using TOFE 10MG TABLET 10'S for a longer period. Inform your physician if you face any symptoms of a blood clot.

How long does it take TOFE 10MG TABLET 10'S to work?Arrow

TOFE 10MG TABLET 10'S is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.

NULL interaction of TOFE 10MG TABLET 10'S with other drungsArrow

There are no known significant interactions of TOFE 10MG TABLET 10'S with other drugs. Always tell your doctor about all the medications you are taking.

What advice should I follow while taking TOFE 10MG TABLET 10'S?Arrow

This medicine may interfere with vaccines, inform your physician about all your vaccination history. This medicine may impair fertility; talk to your doctor before taking this medicine. Your doctor will regularly do lab tests to check whether the medicine is working. Do not breastfeed during the treatment with this medicine and for at least 36 hours after your last dose. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.

What molecule/combination is used for making TOFE 10MG TABLET 10'S?Arrow

TOFACITINIB is molecule/combination used for making TOFE 10MG TABLET 10'S.

For what ailments/diseases/conditions is TOFE 10MG TABLET 10'S prescribed?Arrow

TOFE 10MG TABLET 10'S is prescribed for ailments/diseases/conditions related to Rheumatology and Orthopaedics.

References

Book Icon

XELJANZ 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk.

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HIGHLIGHTS OF PRESCRIBING INFORMATION - Tofacitinib.

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Annex I summary of product characteristics - Tofacitinib.

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Ratings & Review

Good service , great discount, I am regular customer

Gohil Aadityaraj

Reviewed on 27-07-2023

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(5/5)

Good service and affordable price I think best in medical

Pradeep Singh Rathore

Reviewed on 05-11-2022

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(5/5)

One stop solution for medicine

Chintan Joshi

Reviewed on 16-01-2024

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(5/5)

Nice service All required drugs are available 😊

Meet Dobariya

Reviewed on 13-01-2024

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(5/5)

Value for money I got a good discount on medicines

shilpa purohit

Reviewed on 04-09-2023

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(5/5)


Marketer / Manufacturer Details

ALKEM LABORATORIES LIMITED

Country of Origin -

India

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TOFE 10MG TABLET 10'S

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MRP

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₹341.86

15 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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