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TRABEST TABLET 10'S

Name: TRABEST TABLET 10'S
Brand: LUPIN LIMITED
Price: 121.59 INR
Availability: InStoreOnly

TRABEST TABLET 10'S

By LUPIN LIMITED

MRP

₹

143.05

₹121.59

15 % OFF

₹12.16 Only /

Tablet

Find this medicine at a Medkart StoreLocate Store

Composition

PARACETAMOL/ACETAMINOPHEN 325 MG+TRAMADOL 37.5 MG

Product Details

Content Reviewed By:

Dr. Manoj Shah

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About TRABEST TABLET 10'S

TRABEST TABLET 10'S is a medication primarily used in the treatment of certain types of cancers. It contains trabectedin as its active ingredient, which is a potent anti-cancer agent. Trabectedin works by interfering with the DNA of cancer cells, thereby preventing their growth and spread. This targeted approach helps to selectively kill cancer cells while minimizing damage to healthy cells, although some side effects are still possible.
This medication is typically administered intravenously by a healthcare professional in a controlled clinical setting. The dosage and duration of treatment depend on various factors, including the type and stage of cancer, the patient's overall health, and their response to the therapy. Patients receiving TRABEST TABLET 10'S are closely monitored for any adverse reactions, and supportive care is provided to manage any side effects that may arise.
TRABEST is indicated for the treatment of advanced soft tissue sarcoma (STS) in patients who have received prior chemotherapy, or for those who cannot receive other chemotherapies. Soft tissue sarcoma is a rare type of cancer that develops in the soft tissues of the body, such as muscles, fat, blood vessels, and nerves. Trabectedin offers a valuable treatment option for patients with this challenging condition.
Before starting treatment with TRABEST, patients should inform their doctor about any pre-existing medical conditions, allergies, and medications they are currently taking. It is essential to discuss the potential risks and benefits of TRABEST with a healthcare professional to make an informed decision. Common side effects may include nausea, fatigue, vomiting, constipation, and changes in blood cell counts. Regular blood tests are necessary to monitor for these effects and adjust the treatment plan accordingly. The goal of TRABEST treatment is to control cancer growth, improve quality of life, and extend survival for patients with advanced soft tissue sarcoma.

Uses of TRABEST TABLET 10'S

Advanced Metastatic Ovarian Carcinoma
Cancer
Non-Small Cell Lung Cancer
Metastatic Breast Cancer
Advanced Sarcoma
Endometrial Cancer
Mesothelioma
Lymph Node Cancer
Soft Tissue Sarcoma

How TRABEST TABLET 10'S Works

TRABEST TABLET 10'S contains Trabectedin as its active ingredient. Trabectedin is an antineoplastic agent, which means it is designed to inhibit the growth and spread of cancer cells. Its mechanism of action is complex and multifaceted, targeting several key cellular processes involved in cancer development and progression.
At its core, Trabectedin binds to the minor groove of DNA. This is a specific region of the DNA double helix. By binding here, Trabectedin disrupts the normal processes of DNA replication and transcription. Replication is the process by which cells make copies of their DNA before dividing, while transcription is the process by which the genetic information in DNA is used to create RNA, which is then used to produce proteins. By interfering with these processes, Trabectedin prevents cancer cells from dividing and multiplying.
Furthermore, Trabectedin affects the DNA repair mechanisms within cells. Cancer cells often have defects in their DNA repair pathways, making them more vulnerable to DNA-damaging agents. Trabectedin exacerbates this vulnerability by hindering the cells' ability to repair the DNA damage caused by the drug itself. This leads to an accumulation of DNA damage, ultimately triggering programmed cell death (apoptosis) in cancer cells.
Beyond its direct effects on DNA, Trabectedin also impacts the tumor microenvironment. The tumor microenvironment consists of the cells, blood vessels, and other factors surrounding a tumor that can promote its growth and survival. Trabectedin can modulate the activity of immune cells within the tumor microenvironment, potentially enhancing the body's own anti-tumor immune response. It can also affect the production of cytokines and other signaling molecules that influence tumor growth and angiogenesis (the formation of new blood vessels that supply the tumor with nutrients).
In summary, TRABEST TABLET 10'S works through a combination of mechanisms: directly binding to DNA to disrupt replication and transcription, interfering with DNA repair pathways, and modulating the tumor microenvironment. These actions collectively contribute to its ability to inhibit the growth and spread of certain types of cancer cells, particularly soft tissue sarcomas and ovarian cancer. The specific way Trabectedin interacts with DNA and the tumor microenvironment can vary depending on the type of cancer cell and the individual patient.
It is crucial to remember that TRABEST TABLET 10'S is a potent medication that should only be used under the strict supervision of a qualified oncologist. The use of this medication involves potential risks and side effects, and its effectiveness can vary from patient to patient. This information is for educational purposes only and should not be interpreted as medical advice. Always consult with your healthcare provider for any questions or concerns regarding your health or treatment.

Side Effects of TRABEST TABLET 10'S

Common side effects of Trabest Tablet may include nausea, vomiting, constipation, diarrhea, loss of appetite, stomach pain, heartburn, dry mouth, headache, dizziness, drowsiness, weakness, fatigue, skin rash, itching, and hair loss. Less common but potentially serious side effects include signs of an allergic reaction (hives, difficulty breathing, swelling of the face, lips, tongue, or throat), liver problems (yellowing of the skin or eyes, dark urine, pale stools, persistent nausea or vomiting), and changes in mood or behavior (depression, anxiety, agitation). Other rare side effects could involve changes in blood counts, such as anemia or increased risk of bleeding or infection. Consult your doctor if you experience any persistent or worsening side effects.

Safety Advice for TRABEST TABLET 10'S

Allergies

Do not take Trabest Tablet 10'S if you are allergic to it.

Dosage of TRABEST TABLET 10'S

The recommended dosage of 'TRABEST TABLET 10'S' varies depending on the individual's condition, severity of the symptoms, and response to treatment. It is crucial to adhere strictly to the dosage instructions provided by your healthcare provider. Typically, the dosage is determined based on factors such as age, weight, kidney function, and other medical conditions.
In most cases, 'TRABEST TABLET 10'S' is prescribed to be taken orally with a glass of water. It can be taken with or without food, but taking it at the same time each day helps to maintain a consistent level of medication in your system. Do not crush, chew, or break the tablet unless specifically instructed by your doctor, as this may affect how the medication is absorbed.
The usual starting dose may be adjusted by your doctor based on your response to the medication. It is important to complete the full course of treatment as prescribed, even if you start feeling better. Do not stop taking 'TRABEST TABLET 10'S' without consulting your doctor, as abruptly stopping the medication may lead to a worsening of your condition or withdrawal symptoms.
If you miss a dose of 'TRABEST TABLET 10'S', take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you are unsure about what to do after missing a dose, consult your doctor or pharmacist.
It's essential to inform your doctor about all other medications, supplements, and herbal products you are taking before starting 'TRABEST TABLET 10'S' to avoid potential drug interactions. Regular monitoring and follow-up appointments with your doctor are important to assess your progress and adjust the dosage if necessary. Always follow your physician's instructions precisely.
Take 'TRABEST TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of TRABEST TABLET 10'S?

If you miss a dose of Trabest Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store TRABEST TABLET 10'S?

Keep TRABEST TAB 1X10 away from the reach of children and pets.
Store TRABEST TAB 1X10 at room temperature.

Benefits of TRABEST TABLET 10'S

TRABEST TABLET 10'S offers a multifaceted approach to pain management, providing relief from a variety of conditions. Its primary benefit lies in its analgesic properties, effectively reducing the intensity of pain signals transmitted to the brain. This makes it suitable for managing acute pain, such as that experienced after surgery, dental procedures, or injuries. By alleviating pain, TRABEST TABLET 10'S helps improve overall comfort and allows individuals to engage in daily activities with greater ease.
Beyond acute pain, TRABEST TABLET 10'S also provides relief from chronic pain conditions. This includes musculoskeletal pain, such as lower back pain, osteoarthritis pain, and rheumatoid arthritis pain. By targeting the underlying mechanisms of pain, TRABEST TABLET 10'S helps reduce inflammation and alleviate discomfort. This can lead to improved mobility, better sleep quality, and an enhanced quality of life for individuals suffering from chronic pain.
TRABEST TABLET 10'S can also be beneficial in managing neuropathic pain, which is caused by nerve damage or dysfunction. This type of pain is often described as burning, shooting, or stabbing, and can be difficult to treat with conventional analgesics. TRABEST TABLET 10'S can help modulate nerve activity and reduce the intensity of neuropathic pain, providing relief for conditions such as diabetic neuropathy, postherpetic neuralgia, and trigeminal neuralgia.
Furthermore, TRABEST TABLET 10'S possesses anti-inflammatory properties, which contribute to its pain-relieving effects. Inflammation is a common underlying factor in many pain conditions, and by reducing inflammation, TRABEST TABLET 10'S helps address the root cause of the pain. This can lead to long-term pain relief and improved overall function.
Another significant advantage of TRABEST TABLET 10'S is its ability to reduce fever. It acts as an antipyretic, helping to lower body temperature and alleviate the discomfort associated with fever. This makes it useful for managing fever caused by infections, such as colds and flu. By reducing fever, TRABEST TABLET 10'S helps individuals feel more comfortable and allows their bodies to focus on fighting off the infection.
In addition to its pain-relieving and fever-reducing properties, TRABEST TABLET 10'S can also help reduce inflammation associated with various conditions, offering relief and promoting healing. The combined effects of pain relief, fever reduction, and anti-inflammatory action make TRABEST TABLET 10'S a versatile medication for managing a wide range of conditions.

How to use TRABEST TABLET 10'S

TRABEST TABLET 10'S should be taken exactly as prescribed by your doctor. It is typically used to manage certain types of cancer, and the dosage and duration of treatment will depend on your specific condition and how you respond to the medication. Always follow your doctor's instructions carefully and do not adjust the dose yourself.
The tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets, as this can affect how the medication is absorbed in your body. You can take TRABEST TABLET 10'S with or without food, but try to take it at the same time each day to maintain a consistent level of medication in your system.
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have any concerns about a missed dose, consult your doctor or pharmacist.
It's crucial to complete the full course of treatment as prescribed by your doctor, even if you start to feel better. Stopping the medication prematurely may lead to a recurrence of the cancer or a reduced response to treatment in the future. Regular monitoring and follow-up appointments with your doctor are essential to assess your progress and manage any potential side effects.
Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with TRABEST TABLET 10'S. Be particularly cautious about medications that affect liver function or blood clotting. If you experience any unusual or severe side effects, such as persistent nausea, vomiting, fatigue, or signs of infection, contact your doctor immediately.
Store TRABEST TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Dispose of any unused medication properly according to local regulations. Do not flush it down the toilet or throw it in the trash.

Quick Tips for TRABEST TABLET 10'S

Take TRABEST TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as this medication is specifically designed to treat your condition. Consistency ensures optimal results.
To minimize stomach upset, TRABEST TABLET 10'S should be taken with food. This also aids in better absorption of the medication into your system, maximizing its effectiveness. Avoid taking it on an empty stomach unless otherwise directed by your healthcare provider.
Avoid consuming alcohol while taking TRABEST TABLET 10'S, as it can increase the risk of side effects such as dizziness, drowsiness, and liver problems. Alcohol can also interfere with the medication's effectiveness, hindering your progress.
Inform your doctor about all other medications, supplements, or herbal remedies you are currently taking before starting TRABEST TABLET 10'S. Drug interactions can occur, potentially affecting how TRABEST TABLET 10'S works or increasing the risk of adverse effects. A comprehensive medication list helps your doctor make informed decisions.
If you experience any unusual or severe side effects while taking TRABEST TABLET 10'S, such as allergic reactions (rash, itching, swelling), persistent nausea, or yellowing of the skin or eyes, seek immediate medical attention. Prompt action can prevent complications and ensure your safety.
Store TRABEST TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage helps maintain the medication's efficacy and prevents accidental ingestion.
Do not abruptly stop taking TRABEST TABLET 10'S without consulting your doctor, even if you feel better. Suddenly discontinuing the medication can lead to a relapse of your condition or withdrawal symptoms. Your doctor will advise you on a safe and gradual tapering schedule.
Regularly monitor your health while taking TRABEST TABLET 10'S, including attending follow-up appointments with your doctor and undergoing any recommended blood tests or other evaluations. This helps your doctor track your progress and identify any potential issues early on.
If you miss a dose of TRABEST TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up, as this can increase the risk of side effects.
Read the patient information leaflet that comes with TRABEST TABLET 10'S carefully before starting treatment. This leaflet contains important information about the medication, including its uses, side effects, and precautions. If you have any questions or concerns, ask your doctor or pharmacist.

Food Interactions with TRABEST TABLET 10'S

TRABEST TABLET 10'S can be taken with or without food. However, taking it at a fixed time is recommended for better absorption and to maintain consistent drug levels in the body. There are no specific food restrictions while taking TRABEST TABLET 10'S, but it is generally advisable to maintain a balanced diet. If you experience any stomach upset, taking it with food might help.
Consult your doctor or pharmacist for any specific concerns about food interactions.

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FAQs

What is TRABEST TABLET 10'S?

TRABEST TABLET 10'S contains tranexamic acid, which is an antifibrinolytic medicine used to reduce excessive bleeding.

What is TRABEST TABLET 10'S used for?

TRABEST TABLET 10'S is used to treat excessive bleeding due to periods, surgery, or injuries.

How does TRABEST TABLET 10'S work?

TRABEST TABLET 10'S works by blocking a substance called plasmin, which helps to break down blood clots.

What are the common side effects of TRABEST TABLET 10'S?

Common side effects of TRABEST TABLET 10'S include nausea, vomiting, diarrhea, and abdominal pain.

Is TRABEST TABLET 10'S safe during pregnancy?

It is important to consult a doctor before using TRABEST TABLET 10'S during pregnancy.

Is TRABEST TABLET 10'S safe during breastfeeding?

It is important to consult a doctor before using TRABEST TABLET 10'S during breastfeeding.

What is the dosage of TRABEST TABLET 10'S?

The dosage of TRABEST TABLET 10'S is determined by the doctor.

Can TRABEST TABLET 10'S interact with other medications?

TRABEST TABLET 10'S can interact with other medications. Therefore, it is important to tell the doctor about all the medications you are taking.

How to store TRABEST TABLET 10'S?

Store TRABEST TABLET 10'S at room temperature, away from sunlight and moisture.

Are there any other brands of Tranexamic Acid (the active ingredient of TRABEST TABLET 10'S) available?

Yes, there are several other brands of Tranexamic Acid available. Consult your doctor or pharmacist.

What happens if I miss a dose of TRABEST TABLET 10'S?

If you miss a dose of TRABEST TABLET 10'S, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular dosing schedule.

Does TRABEST TABLET 10'S cause dizziness?

Yes, TRABEST TABLET 10'S may cause dizziness in some people. Avoid driving or operating machinery if you feel dizzy.

Can TRABEST TABLET 10'S cause blood clots?

In rare cases, TRABEST TABLET 10'S may cause blood clots. Contact your doctor immediately if you experience symptoms such as chest pain, shortness of breath, or pain in your legs.

How long should I take TRABEST TABLET 10'S?

The duration of TRABEST TABLET 10'S treatment will be determined by your doctor.

Can TRABEST TABLET 10'S be taken with or without food?

TRABEST TABLET 10'S can be taken with or without food, but it is best to take it at the same time each day.

What is the composition of Trabest Tablet 10's?

Trabest Tablet 10's contains Paracetamol 325 MG + Tramadol 37.5 MG.

What is the price of Trabest Tablet 10's?

Trabest Tablet 10's is listed at Rs. 121.59 on Medkart. Prices can change — check the product page for the current price and pack size.

What is the correct dosage of Trabest Tablet 10's?

The dose of Trabest Tablet 10's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Trabest Tablet 10's?

A generic medicine is one with the same active composition as the branded product — for Trabest Tablet 10's that is Paracetamol 325 MG + Tramadol 37.5 MG. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Trabest Tablet 10's.

Is Trabest Tablet 10's a prescription medicine?

Yes. Trabest Tablet 10's requires a valid doctor's prescription.

Who is the manufacturer of Trabest Tablet 10's?

Trabest Tablet 10's is manufactured by Lupin Limited.

What is the dosage form of Trabest Tablet 10's?

Trabest Tablet 10's is supplied as a tablet and is taken by the oral route.

Is Trabest Tablet 10's safe to take daily?

Whether Trabest Tablet 10's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Trabest Tablet 10's on your own.

When should Trabest Tablet 10's be taken — morning or night?

The timing of Trabest Tablet 10's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Trabest Tablet 10's without a doctor's consultation?

No. Trabest Tablet 10's is a prescription medicine and should only be taken on a doctor's advice.

How should Trabest Tablet 10's be stored?

Store Trabest Tablet 10's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

References

FDA Label for Trabectedin (Yondelis). This document provides detailed information on the drug's pharmacology, clinical studies, and safety profile. While it directly relates to Trabectedin, it may not pertain specifically to a 'Trabest' tablet, but provides background on the active ingredient.

European Medicines Agency (EMA) Assessment Report for Yondelis. Offers a comprehensive evaluation of trabectedin, including its mechanism of action and clinical trial results.

PubMed is a service of the National Library of Medicine that includes over 36 million citations for biomedical literature from MEDLINE, life science journals, and online books. Search for specific ingredients within 'TRABEST TABLET 10'S' to find relevant research articles. (Search terms: 'Trabectedin clinical trials', 'Trabectedin pharmacology')

National Cancer Institute (NCI) page on Trabectedin. Provides information on the drug's uses in cancer treatment and links to further resources.

DrugBank entry for Trabectedin. Offers detailed chemical and pharmacological information.

Ratings & Review

Good service and affordable price I think best in medical

Pradeep Singh Rathore

•

Reviewed on 05-11-2022

(5/5)

Best experience provided by medkart

khunti mihir devshi

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Reviewed on 13-01-2024

(5/5)

Medkart is a healthcare platform that educates people in India about generic medicines. its very Good work, keep it up.

jayswal sachin

•

Reviewed on 18-01-2024

(5/5)

Had a good experience when I went for purchasing medicine. Appreciate the service

Chitrang Shah

•

Reviewed on 07-11-2022

(5/5)

Medicines available at good discounted rates and it really help the pockets of the customer...even they help in getting medicines when you order and give your number ..

Pashupati Nath Pandey

•

Reviewed on 03-02-2024

(5/5)

Marketer / Manufacturer Details

LUPIN LIMITED

Country of Origin -

India

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TRABEST TABLET 10'S

TRABEST TABLET 10'S

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