TRAPMOL TABLET 10'S

How TRAPMOL TABLET 10'S Works

• TRAPMOL TABLET 10'S is a combination medication designed to provide effective pain relief and reduce fever. It contains two active ingredients: Tramadol and Paracetamol. Each component works through different mechanisms to achieve its therapeutic effects, and their combined action offers a synergistic approach to pain management.
• Tramadol is a centrally acting analgesic, meaning it works within the central nervous system (brain and spinal cord) to alleviate pain. It has a dual mechanism of action. First, it binds to the μ-opioid receptor, a receptor site in the brain that is also targeted by opioid analgesics. By binding to this receptor, tramadol reduces the perception of pain signals transmitted to the brain. Second, tramadol inhibits the reuptake of norepinephrine and serotonin, two neurotransmitters that play a role in pain modulation. By preventing their reuptake, tramadol increases the levels of these neurotransmitters in the synaptic cleft (the space between nerve cells), which further helps to reduce pain.
• Paracetamol, also known as acetaminophen, is an analgesic and antipyretic (fever-reducing) agent. Its mechanism of action is not fully understood, but it is believed to primarily act by inhibiting prostaglandin synthesis in the brain. Prostaglandins are substances that contribute to pain and inflammation. By reducing prostaglandin production, paracetamol helps to alleviate pain and reduce fever. Paracetamol also affects the thermoregulatory center in the brain, helping to lower body temperature during fever.
• When tramadol and paracetamol are combined in TRAPMOL TABLET 10'S, they provide a more comprehensive approach to pain relief than either medication could achieve alone. Tramadol addresses pain signals centrally through opioid receptor binding and neurotransmitter modulation, while paracetamol reduces pain and fever peripherally by inhibiting prostaglandin synthesis. This synergistic action results in enhanced pain relief and improved patient outcomes, especially in conditions involving moderate to severe pain accompanied by fever.
• In summary, TRAPMOL TABLET 10'S works by utilizing the complementary mechanisms of tramadol and paracetamol. Tramadol modulates pain signals in the central nervous system, while paracetamol reduces pain and fever by inhibiting prostaglandin synthesis. This combined approach provides effective pain relief and fever reduction for various conditions.

Like all medicines, TRAPMOL TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Nausea * Vomiting * Constipation * Headache * Dizziness * Drowsiness * Sweating **Uncommon Side Effects (may affect up to 1 in 100 people):** * Abdominal pain * Dry mouth * Diarrhea * Anxiety * Confusion * Sleep disturbances * Itching * Rash **Rare Side Effects (may affect up to 1 in 1,000 people):** * Allergic reaction (symptoms may include swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing) * Liver problems (symptoms may include yellowing of the skin or eyes, dark urine, abdominal pain) * Kidney problems (symptoms may include changes in urine output, swelling of the ankles or feet) * Seizures * Changes in blood pressure * Hallucinations **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Severe skin reactions (symptoms may include blistering, peeling, or severe rash) * Breathing difficulties * Coma **If you experience any side effects, even those not listed above, talk to your doctor or pharmacist. You can also report side effects directly to the Medicines and Healthcare products Regulatory Agency (MHRA).**

• If you miss a dose of Trapmol Tablet 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep TRAPMOL TAB 1X10 away from the reach of children and pets.
• Store TRAPMOL TAB 1X10 at room temperature.

• **Understand Your Dosage:** Always take TRAPMOL TABLET 10'S exactly as prescribed by your doctor. Never exceed the recommended dose, even if you feel your pain isn't fully controlled. Overdosing can lead to serious liver damage and other adverse effects. If you are unsure about the correct dosage, double-check with your pharmacist or doctor.
• **Be Mindful of Other Medications:** TRAPMOL TABLET 10'S can interact with other medications, including over-the-counter drugs, herbal remedies, and supplements. Inform your doctor about all medications you are currently taking to avoid potential interactions. Special caution is needed if you are taking blood thinners, certain antidepressants, or other pain relievers.
• **Take with or Without Food:** TRAPMOL TABLET 10'S can be taken with or without food. However, if you experience stomach upset, taking it with food may help. If you have any concerns about how food affects the medication, consult your doctor or pharmacist. Consistency in how you take the medicine can help manage your symptoms effectively.
• **Avoid Alcohol Consumption:** Alcohol can significantly increase the risk of liver damage when taken with TRAPMOL TABLET 10'S. It's crucial to avoid alcohol consumption while using this medication. Alcohol can also worsen some of the side effects of TRAPMOL TABLET 10'S, such as drowsiness and dizziness.
• **Report Side Effects Promptly:** While TRAPMOL TABLET 10'S is generally well-tolerated, some people may experience side effects such as nausea, vomiting, or constipation. If you experience any persistent or bothersome side effects, inform your doctor immediately. Serious side effects, such as allergic reactions, jaundice (yellowing of the skin or eyes), or severe abdominal pain, require immediate medical attention.

• TRAPMOL TABLET 10'S can be taken with or without food. However, if you experience stomach upset, taking it with food may help.
• Avoid consuming large amounts of grapefruit juice while taking this medication, as it may increase the drug's concentration in your blood.