TRAJENTA DUO 2.5/1000MG TABLET 10'S
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TRAJENTA DUO 2.5/1000MG TABLET 10'S
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TRAJENTA DUO 2.5/1000MG TABLET 10'S

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TRAJENTA DUO 2.5/1000MG TABLET 10'S

By BOEHRINGER INGELHEIM INDIA PVT LTD

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204

₹173.4

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About TRAJENTA DUO 2.5/1000MG TABLET 10'S

  • TRAJENTA DUO 2.5/1000MG TABLET is a combination medicine designed to help adults manage their type 2 diabetes. It contains two active ingredients: linagliptin and metformin hydrochloride. Linagliptin belongs to a class of drugs called DPP-4 inhibitors, which work by increasing the amount of insulin your body produces after eating and decreasing the amount of glucose your liver makes. Metformin, on the other hand, is a biguanide that reduces glucose production in the liver and improves your body's sensitivity to insulin.
  • This dual-action approach helps to effectively lower blood sugar levels in individuals with type 2 diabetes, especially when diet and exercise alone are not sufficient. TRAJENTA DUO is typically prescribed as part of a comprehensive diabetes management plan that includes lifestyle modifications such as a healthy diet, regular physical activity, and weight management.
  • The 2.5/1000mg strength indicates that each tablet contains 2.5mg of linagliptin and 1000mg of metformin hydrochloride. It is crucial to take this medication exactly as prescribed by your doctor. The usual dosage is one tablet taken orally, once or twice daily, with meals to help reduce stomach upset from metformin. Swallow the tablet whole with a glass of water and do not crush or chew it.
  • Before starting TRAJENTA DUO, inform your doctor about any other medical conditions you may have, especially kidney or liver problems, heart failure, or a history of pancreatitis. Also, disclose all other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with this medicine. Common side effects of TRAJENTA DUO may include diarrhea, nausea, vomiting, and abdominal pain. If you experience any severe or persistent side effects, seek medical attention immediately.
  • TRAJENTA DUO 2.5/1000MG TABLET is a prescription medication and should only be used under the guidance of a healthcare professional. Regular monitoring of blood sugar levels and kidney function is essential while taking this medicine to ensure its effectiveness and safety. This medication helps improve glycemic control in conjunction with a proper diet and exercise program for better diabetes management.

Uses of TRAJENTA DUO 2.5/1000MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control when used along with diet and exercise
  • Management of type 2 diabetes in adults

Side Effects of TRAJENTA DUO 2.5/1000MG TABLET 10'SArrow

Possible side effects of TRAJENTA DUO 2.5/1000MG TABLET may include: * **Common Side Effects:** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Headache * Upper respiratory tract infection symptoms (e.g., runny nose, sore throat) * Hypoglycemia (low blood sugar) when used with other diabetes medications like sulfonylureas or insulin. * **Uncommon Side Effects:** * Skin rash or itching * Urticaria (hives) * Constipation * Flatulence * Heartburn * Edema (swelling, especially in the ankles and feet) * Joint pain (arthralgia) * Muscle pain (myalgia) * Pancreatitis (inflammation of the pancreas) - seek immediate medical attention if you experience severe abdominal pain, possibly radiating to the back, with or without vomiting. * Bullous Pemphigoid (a serious skin condition that causes blisters) * Vitamin B12 deficiency (long-term use of metformin can interfere with B12 absorption) * **Rare Side Effects:** * Lactic acidosis (a serious metabolic complication due to metformin accumulation) - seek immediate medical attention if you experience symptoms like weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, or stomach pain. * Severe allergic reactions (anaphylaxis) - seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face, lips, tongue, or throat, or rash. This is not an exhaustive list. Inform your doctor if you experience any unusual or bothersome symptoms while taking TRAJENTA DUO.

Safety Advice for TRAJENTA DUO 2.5/1000MG TABLET 10'SArrow

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Allergies

Allergies

Inform your doctor if you are allergic to any of the ingredients present in TRAJENTA DUO 2.5/1000MG TABLET 10'S.

Dosage of TRAJENTA DUO 2.5/1000MG TABLET 10'SArrow

  • The recommended dosage of TRAJENTA DUO 2.5/1000MG TABLET 10'S varies depending on individual patient needs, existing treatments, and kidney function. It is crucial to adhere strictly to your doctor's instructions regarding dosage and timing.
  • Typically, the starting dose for patients not currently on metformin is 2.5mg of linagliptin/500mg of metformin hydrochloride twice daily. For patients already taking metformin, the starting dose should provide linagliptin 2.5mg plus the current dose of metformin.
  • The maximum recommended daily dose of linagliptin is 5mg. The dosage of metformin should be titrated gradually to the lowest effective dose to minimize gastrointestinal side effects. Dosage adjustments should be made based on individual glycemic control and tolerability, up to a maximum daily dose of 2000mg of metformin.
  • TRAJENTA DUO 2.5/1000MG TABLET 10'S should be taken with meals to reduce gastrointestinal side effects associated with metformin. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • Patients with renal impairment may require dosage adjustments. Regular monitoring of kidney function is essential, especially in elderly patients, as metformin is primarily eliminated by the kidneys. Your doctor will determine the appropriate dosage based on your kidney function test results. If you have severe kidney disease, TRAJENTA DUO 2.5/1000MG TABLET 10'S is contraindicated.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Take 'TRAJENTA DUO 2.5/1000MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of TRAJENTA DUO 2.5/1000MG TABLET 10'S?Arrow

  • If you miss a dose of TRAJENTA DUO, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store TRAJENTA DUO 2.5/1000MG TABLET 10'S?Arrow

  • Keep TRAJENTA DUO 2.5/1000MG TAB 1X10 away from the reach of children and pets.
  • Store TRAJENTA DUO 2.5/1000MG TAB 1X10 at room temperature.

Benefits of TRAJENTA DUO 2.5/1000MG TABLET 10'SArrow

  • TRAJENTA DUO 2.5/1000MG TABLET 10'S is a combination medicine designed to effectively manage blood sugar levels in adults with type 2 diabetes mellitus. It combines two powerful active ingredients: linagliptin and metformin, each working through different mechanisms to provide comprehensive glycemic control. This dual-action approach makes it a valuable tool in diabetes management.
  • One of the primary benefits of TRAJENTA DUO is its ability to improve glycemic control. Linagliptin, a DPP-4 inhibitor, enhances the levels of incretin hormones in the body. These hormones stimulate insulin release and reduce glucagon secretion in a glucose-dependent manner. This means that linagliptin helps the pancreas produce more insulin when blood sugar is high and reduces the liver's production of glucose, contributing to better blood sugar regulation throughout the day.
  • Metformin, the other key ingredient, primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It also reduces the absorption of glucose from the intestines. By addressing multiple pathways of glucose dysregulation, TRAJENTA DUO offers a more robust approach to managing blood sugar compared to using either medication alone.
  • TRAJENTA DUO has been shown to significantly reduce HbA1c levels, a measure of average blood sugar over the past 2-3 months. Lowering HbA1c is crucial for reducing the risk of long-term complications associated with diabetes, such as heart disease, kidney disease, nerve damage, and eye problems. Consistent use of TRAJENTA DUO, as prescribed by a healthcare provider, can lead to better overall health outcomes.
  • Another significant advantage of TRAJENTA DUO is its convenience. As a combination tablet, it simplifies the medication regimen by combining two medications into a single dose. This can improve adherence to treatment, as patients are more likely to take their medication as prescribed when it's easier to manage. Improved adherence leads to better blood sugar control and reduces the risk of complications.
  • TRAJENTA DUO is generally well-tolerated. Linagliptin has a low risk of causing hypoglycemia (low blood sugar) when used alone, and metformin, while it can sometimes cause gastrointestinal side effects, is generally safe for most people. The combination of these two medications can provide effective blood sugar control with a manageable side effect profile.
  • Beyond glycemic control, TRAJENTA DUO may offer additional benefits. Some studies suggest that linagliptin may have a protective effect on the kidneys and cardiovascular system. Metformin has also been associated with modest weight loss or weight stabilization, which can be beneficial for overweight or obese individuals with type 2 diabetes. These additional benefits contribute to the overall value of TRAJENTA DUO in managing diabetes and promoting overall health.
  • TRAJENTA DUO is an effective and convenient option for managing type 2 diabetes, offering improved glycemic control, reduced risk of complications, and potential additional benefits for kidney and cardiovascular health. Its dual-action mechanism and simplified dosing make it a valuable tool in the comprehensive management of type 2 diabetes mellitus.
  • It is crucial to use TRAJENTA DUO as part of a comprehensive diabetes management plan, which includes lifestyle modifications such as diet and exercise. Regular monitoring of blood sugar levels and close communication with a healthcare provider are also essential for optimizing treatment and preventing complications.

How to use TRAJENTA DUO 2.5/1000MG TABLET 10'SArrow

  • TRAJENTA DUO 2.5/1000MG TABLET 10'S is an oral medication used to manage type 2 diabetes. It combines two active ingredients: linagliptin and metformin. Linagliptin belongs to a class of drugs called DPP-4 inhibitors, which work by increasing the amount of incretin hormones in the body. These hormones help to stimulate insulin release and decrease glucagon secretion, both of which lower blood sugar levels. Metformin, on the other hand, is a biguanide that works by decreasing glucose production in the liver and improving insulin sensitivity.
  • To use TRAJENTA DUO effectively, it is crucial to follow your doctor's instructions carefully. The usual starting dose is one tablet once or twice daily, taken with meals to reduce the risk of stomach upset. The specific dosage and frequency will depend on your individual needs and response to the medication. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. It is best to take it at the same time(s) each day to maintain a consistent level of medication in your body.
  • Consistency is key when taking TRAJENTA DUO. Missing doses can lead to fluctuations in blood sugar levels, making it harder to manage your diabetes. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • TRAJENTA DUO is most effective when combined with a healthy diet and regular exercise. Work with your doctor or a registered dietitian to develop a meal plan that is appropriate for your needs. Engage in regular physical activity, such as brisk walking, jogging, or swimming, for at least 30 minutes most days of the week. Regular monitoring of your blood sugar levels is also important to assess how well the medication is working and to make any necessary adjustments to your treatment plan.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with TRAJENTA DUO. Pay attention to any potential side effects, such as nausea, vomiting, diarrhea, or abdominal pain. If you experience any persistent or bothersome side effects, consult your doctor. In rare cases, metformin can cause a serious side effect called lactic acidosis, which requires immediate medical attention. Symptoms of lactic acidosis include weakness, muscle pain, trouble breathing, stomach pain with nausea and vomiting, dizziness, feeling cold, and slow or irregular heartbeat. If you experience any of these symptoms, seek emergency medical help immediately.

Quick Tips for TRAJENTA DUO 2.5/1000MG TABLET 10'SArrow

  • Take TRAJENTA DUO 2.5/1000MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them, as this could affect your blood sugar levels and overall health. It is typically taken twice daily with meals to help manage blood sugar levels effectively.
  • To maximize the benefits of TRAJENTA DUO, maintain a consistent meal schedule and a balanced diet. Focus on incorporating fiber-rich foods, lean proteins, and healthy fats into your meals. Avoid excessive amounts of sugary foods and beverages, as these can counteract the effects of the medication. Regular physical activity is also essential for managing blood sugar levels.
  • Be aware of the potential side effects of TRAJENTA DUO, such as gastrointestinal issues like nausea, diarrhea, or stomach upset. If you experience any persistent or severe side effects, inform your doctor promptly. Also, watch out for signs of hypoglycemia (low blood sugar), such as sweating, shakiness, confusion, or dizziness. Keep a source of fast-acting sugar (e.g., glucose tablets, juice) readily available to treat hypoglycemia if it occurs. Report any unusual symptoms to your healthcare provider.
  • Regularly monitor your blood sugar levels as directed by your doctor. Keeping track of your blood sugar readings helps you and your doctor assess how well TRAJENTA DUO is working and make any necessary adjustments to your treatment plan. Bring your blood sugar log to your doctor's appointments for review. Also, make sure to attend all scheduled check-ups with your doctor and eye doctor to monitor your overall health and detect any potential complications early.
  • Store TRAJENTA DUO 2.5/1000MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Check the expiration date on the packaging and do not use the medication if it has expired. If you have any unused or expired medication, dispose of it properly according to your local regulations. Always consult with your pharmacist or doctor if you have any questions about storing or disposing of your medication.
  • Ensure adequate hydration throughout the day by drinking plenty of water. Proper hydration supports overall health and can also help manage blood sugar levels. Avoid sugary drinks, as they can negatively impact your blood sugar. Also, inform your doctor about any other medications, supplements, or herbal products you are taking, as they may interact with TRAJENTA DUO. It's crucial for your doctor to have a complete picture of your health and medications to ensure safe and effective treatment.

Food Interactions with TRAJENTA DUO 2.5/1000MG TABLET 10'SArrow

  • TRAJENTA DUO 2.5/1000MG TABLET 10'S can be taken with or without food. However, it is advisable to take it with meals to reduce the risk of gastrointestinal side effects such as nausea or stomach upset. Consistent timing of administration, relative to meals, is recommended to maintain stable blood sugar levels. Consult your doctor for personalized advice.

FAQs

What is the use of Trajenta Duo 2.5/1000mg Tablet 10's?Arrow

Trajenta Duo 2.5/1000mg Tablet 10's is used to treat type 2 diabetes mellitus. It helps control blood sugar levels.

What are the common side effects of Trajenta Duo 2.5/1000mg Tablet 10's?Arrow

Common side effects of Trajenta Duo 2.5/1000mg Tablet 10's include nausea, vomiting, diarrhea, and stomach pain.

How should Trajenta Duo 2.5/1000mg Tablet 10's be stored?Arrow

Trajenta Duo 2.5/1000mg Tablet 10's should be stored at room temperature, away from moisture and direct sunlight.

Is Trajenta Duo 2.5/1000mg Tablet 10's safe during pregnancy?Arrow

There is limited information regarding the safety of Trajenta Duo 2.5/1000mg Tablet 10's during pregnancy. Therefore, it is important to consult a doctor before taking it.

Is Trajenta Duo 2.5/1000mg Tablet 10's safe for breastfeeding women?Arrow

There is limited information regarding the safety of Trajenta Duo 2.5/1000mg Tablet 10's for breastfeeding women. Therefore, it is important to consult a doctor before taking it.

What is the dosage of Trajenta Duo 2.5/1000mg Tablet 10's?Arrow

The dosage of Trajenta Duo 2.5/1000mg Tablet 10's is determined by the doctor. The dosage depends on the individual's condition and response to treatment.

What happens if I miss a dose of Trajenta Duo 2.5/1000mg Tablet 10's?Arrow

If you miss a dose of Trajenta Duo 2.5/1000mg Tablet 10's, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Is it safe to drink alcohol with Trajenta Duo 2.5/1000mg Tablet 10's?Arrow

Drinking alcohol with Trajenta Duo 2.5/1000mg Tablet 10's can lower blood sugar levels. Therefore, it is important to consult a doctor before taking it.

Does Trajenta Duo 2.5/1000mg Tablet 10's interact with other medications?Arrow

Trajenta Duo 2.5/1000mg Tablet 10's can interact with certain medications. Therefore, it is important to tell your doctor about all your medications before taking it.

How does Trajenta Duo 2.5/1000mg Tablet 10's work?Arrow

Trajenta Duo 2.5/1000mg Tablet 10's is a combination of two medicines: linagliptin and metformin. Linagliptin belongs to a class of medications called DPP-4 inhibitors. It works by increasing the release of insulin and decreasing the secretion of glucagon. Metformin belongs to a class of medications called biguanides. It works by decreasing the amount of glucose produced by the liver and increasing the body's sensitivity to insulin.

Does Trajenta Duo 2.5/1000mg Tablet 10's cause weight gain?Arrow

Trajenta Duo 2.5/1000mg Tablet 10's does not usually cause weight gain. However, some people may experience it.

Is Trajenta Duo 2.5/1000mg Tablet 10's safe for people with kidney problems?Arrow

People with kidney problems should consult a doctor before taking Trajenta Duo 2.5/1000mg Tablet 10's, as it may worsen their condition.

Can I take Trajenta Duo 2.5/1000mg Tablet 10's with other diabetes medications?Arrow

It is important to consult a doctor before taking Trajenta Duo 2.5/1000mg Tablet 10's with other diabetes medications, as it may cause blood sugar levels to drop too low.

How long does it take for Trajenta Duo 2.5/1000mg Tablet 10's to work?Arrow

It may take a few days for Trajenta Duo 2.5/1000mg Tablet 10's to start working.

What are some other medications containing Metformin?Arrow

Some other medications containing Metformin include Glucophage, Glucophage XR, Fortamet, Riomet, and Metformin ER.

What are some other medications containing Linagliptin?Arrow

Trajenta is another medication containing Linagliptin.

References

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Kombiglyze XR (metformin hydrochloride and saxagliptin hydrochloride) extended-release tablets. U.S. Food and Drug Administration. Label.

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Trajenta (linagliptin). European Medicines Agency. EPAR.

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Linagliptin. DrugBank.

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Metformin. DrugBank.

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Linagliptin: a novel DPP-4 inhibitor with favorable properties.

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Efficacy and safety of linagliptin added to metformin in patients with type 2 diabetes inadequately controlled with metformin alone: a 24-week, randomised, double-blind, placebo-controlled study.

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Linagliptin as add-on to metformin in patients with type 2 diabetes: a double-blind randomized controlled trial.

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FDA Pharmacology Review for Tradjenta (linagliptin).

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TRAJENTA DUO 2.5/1000MG TABLET 10'S

TRAJENTA DUO 2.5/1000MG TABLET 10'S

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