TRAJENTA DUO 2.5/500MG TABLET 10'S

How TRAJENTA DUO 2.5/500MG TABLET 10'S Works

• TRAJENTA DUO 2.5/500MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines two active ingredients, linagliptin and metformin, each working through different mechanisms to lower blood glucose levels. Linagliptin belongs to a class of drugs called DPP-4 inhibitors, while metformin is a biguanide.
• Linagliptin works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). DPP-4 breaks down incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These incretin hormones play a crucial role in regulating blood sugar levels. GLP-1, for example, stimulates insulin release from the pancreas when blood glucose levels are high and reduces glucagon secretion from the pancreas, which prevents the liver from releasing stored glucose. By inhibiting DPP-4, linagliptin increases the levels of active incretin hormones in the body. This results in enhanced insulin secretion in response to meals and decreased glucagon secretion, both of which help lower blood sugar levels.
• Metformin, on the other hand, primarily works by decreasing glucose production in the liver. It reduces hepatic glucose output by suppressing gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, metformin improves insulin sensitivity in peripheral tissues such as muscle, allowing cells to utilize glucose more effectively. It also slows down the absorption of glucose from the intestines after a meal. Unlike some other diabetes medications, metformin does not typically cause weight gain and may even lead to modest weight loss in some individuals.
• When linagliptin and metformin are combined in TRAJENTA DUO, they provide complementary effects that help to control blood glucose levels more effectively than either drug alone. Linagliptin enhances insulin secretion and reduces glucagon secretion, while metformin reduces glucose production in the liver and improves insulin sensitivity. This dual mechanism of action helps to address the multiple factors that contribute to high blood sugar levels in type 2 diabetes. TRAJENTA DUO is typically taken with meals to maximize its effectiveness and minimize potential gastrointestinal side effects associated with metformin.
• In summary, TRAJENTA DUO 2.5/500MG TABLET 10'S helps to lower blood sugar levels by increasing insulin release, decreasing glucagon secretion, reducing glucose production in the liver, and improving insulin sensitivity. This comprehensive approach makes it a valuable option for managing type 2 diabetes.

TRAJENTA DUO 2.5/500MG TABLET 10'S can cause several side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and metallic taste. Some patients may experience hypoglycemia (low blood sugar), especially when taken with other diabetes medications like sulfonylureas or insulin. Symptoms of hypoglycemia include shakiness, sweating, anxiety, blurred vision, rapid heartbeat, and confusion. Less common but potentially serious side effects include pancreatitis (inflammation of the pancreas), which can cause severe abdominal pain, and allergic reactions, such as rash, itching, swelling, or difficulty breathing. In rare cases, lactic acidosis (a buildup of lactic acid in the blood) can occur, presenting symptoms like weakness, muscle pain, trouble breathing, stomach pain, and dizziness. Upper respiratory tract infections and headache have also been reported. It's important to contact your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of TRAJENTA DUO 2.5/500MG TABLET 10'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep TRAJENTA DUO 2.5/500MG TAB 1X10 away from the reach of children and pets.
• Store TRAJENTA DUO 2.5/500MG TAB 1X10 at room temperature.

• Take TRAJENTA DUO 2.5/500MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or discontinue the medication without consulting them, as this can affect your blood sugar control.
• Administer TRAJENTA DUO 2.5/500MG TABLET 10'S with food to minimize potential gastrointestinal discomfort, such as nausea or stomach upset. Consistency in timing with meals each day is helpful.
• Monitor your blood sugar levels regularly, as directed by your healthcare provider, while taking TRAJENTA DUO 2.5/500MG TABLET 10'S. Keep a log of your readings to share with your doctor during follow-up appointments. This will help to see how well the medicine is working.
• Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. These habits, combined with TRAJENTA DUO 2.5/500MG TABLET 10'S, can significantly improve your blood sugar control and overall health. Discuss specific dietary and exercise plans with your doctor or a registered dietitian.
• Stay hydrated by drinking plenty of water throughout the day while taking TRAJENTA DUO 2.5/500MG TABLET 10'S. Adequate hydration supports kidney function, which is important for processing the medication and maintaining overall health. Dehydration can also affect blood sugar levels.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times in case you experience these symptoms. Inform your family and friends about how to help you if your blood sugar gets too low.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting TRAJENTA DUO 2.5/500MG TABLET 10'S. Drug interactions can affect how the medication works and increase the risk of side effects. This includes over-the-counter medicines.
• Store TRAJENTA DUO 2.5/500MG TABLET 10'S at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Proper storage helps ensure that the medication remains effective.
• If you experience any persistent or bothersome side effects, such as severe stomach pain, nausea, or skin rash, contact your doctor promptly. Do not ignore these symptoms, as they could indicate a serious problem.
• Attend all scheduled follow-up appointments with your doctor to monitor your progress and adjust your treatment plan as needed. Regular check-ups are essential for managing your diabetes effectively and preventing complications.