XPRAB INJECTION 1'S

How XPRAB INJECTION 1'S Works

• XPRAB INJECTION 1'S contains Rabeprazole as its active ingredient. Rabeprazole belongs to a class of drugs called proton pump inhibitors (PPIs). It primarily works by reducing the amount of acid produced in the stomach. To understand how it works, it's important to understand the acid production process in the stomach. The cells in the lining of the stomach, called parietal cells, contain a proton pump (H+/K+ ATPase enzyme). This pump is responsible for secreting hydrogen ions (H+) into the stomach lumen, which is a crucial step in the production of hydrochloric acid (HCl), the main acid in the stomach.
• Rabeprazole inhibits this proton pump in the parietal cells. By blocking the action of this pump, Rabeprazole effectively reduces the secretion of hydrogen ions into the stomach. This, in turn, leads to a decrease in the production of hydrochloric acid. The reduction in stomach acid helps to relieve symptoms associated with acid-related conditions such as heartburn, acid reflux, and ulcers. It also creates an environment that promotes the healing of damaged tissue in the esophagus and stomach.
• Specifically, Rabeprazole is a prodrug, meaning it's administered in an inactive form and is converted to its active form within the body. After intravenous administration, Rabeprazole is rapidly converted to its active form, a sulfenamide derivative, within the parietal cells of the stomach. This active form then binds irreversibly to the H+/K+ ATPase enzyme (the proton pump), effectively shutting it down. The irreversible binding means that the enzyme needs to be newly synthesized for acid production to resume, providing a prolonged duration of action.
• Furthermore, XPRAB INJECTION 1'S (Rabeprazole) can be particularly useful in situations where oral administration is not feasible or when a rapid onset of action is required. Intravenous administration allows for direct delivery of the drug into the bloodstream, bypassing the need for absorption through the gastrointestinal tract. This can be advantageous in critically ill patients or those with severe nausea and vomiting. Its action helps to alleviate discomfort, prevent further esophageal damage, and promote healing in patients suffering from acid-related gastrointestinal disorders. Overall, Rabeprazole offers a targeted approach to managing acid production, making it a valuable tool in the treatment of various gastrointestinal conditions.

Like all medicines, XPRAB INJECTION 1'S can cause side effects, although not everybody gets them. **Common Side Effects:** * Injection site reactions (pain, swelling, redness) * Nausea * Headache * Dizziness * Abdominal pain * Diarrhea * Flatulence **Uncommon Side Effects:** * Vomiting * Dry mouth * Increased sweating * Fatigue * Weakness * Skin rash * Itching * Sleep disturbances (insomnia) **Rare Side Effects:** * Hypersensitivity reactions (allergic reactions, including rash, itching, swelling, difficulty breathing) * Changes in liver function tests * Thrombophlebitis (inflammation of a vein with blood clot formation) at the injection site **Very Rare Side Effects:** * Anaphylactic shock (severe allergic reaction) * Blood disorders (changes in blood cell counts) **If you experience any of these side effects or any other unusual symptoms, stop taking XPRAB INJECTION 1'S and consult your doctor immediately.**

• If you miss a dose of XPRAB INJECTION 1'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
• Contact your doctor if you have concerns about missed doses.

• Keep XPRAB INJ 0.5ML away from the reach of children and pets.
• Store XPRAB INJ 0.5ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand the Purpose:** XPRAB INJECTION 1'S is typically used to treat or prevent infections caused by susceptible bacteria. Your doctor will determine if it's the right medication for your specific condition. Do not self-medicate. Only use if prescribed by a registered medical practitioner.
• **Administration:** XPRAB INJECTION 1'S should be administered by a healthcare professional. It is usually given intravenously (into a vein) or intramuscularly (into a muscle). Do not attempt to administer the injection yourself unless you are properly trained and have been instructed to do so by your doctor.
• **Dosage and Schedule:** Strictly adhere to the dosage and schedule prescribed by your doctor. Do not skip doses or discontinue treatment prematurely, even if you start feeling better. Completing the full course of treatment is crucial to eradicate the infection completely and prevent antibiotic resistance.
• **Potential Side Effects:** Be aware of the potential side effects of XPRAB INJECTION 1'S. Common side effects may include pain or irritation at the injection site, nausea, vomiting, or diarrhea. More serious side effects are rare but can occur. If you experience any unusual or severe symptoms, such as difficulty breathing, swelling of the face or throat, rash, or severe abdominal pain, seek immediate medical attention.
• **Drug Interactions:** Inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. XPRAB INJECTION 1'S can interact with certain medications, potentially affecting its effectiveness or increasing the risk of side effects. A comprehensive list of all medications helps your doctor to manage the treatment more effectively.
• **Storage:** While you likely won't be storing this medication at home, if you do receive instructions for storage, carefully follow them. Improper storage can affect the drug's effectiveness. Typically, it needs to be kept in a cool, dry place away from direct sunlight and out of reach of children.
• **Allergies:** Inform your healthcare provider of any known allergies, especially to other antibiotics. Allergic reactions to XPRAB INJECTION 1'S can be severe.
• **Pregnancy and Breastfeeding:** If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of XPRAB INJECTION 1'S with your doctor before starting treatment. It's important to make an informed decision about medication use during these periods.
• **Monitoring:** Your doctor may order blood tests or other monitoring tests to assess your response to XPRAB INJECTION 1'S and to check for any potential side effects. Attend all scheduled appointments and follow your doctor's instructions carefully.

• While XPRAB INJECTION 1'S is administered by a healthcare professional, specific food interactions are not generally a concern. It is typically given intravenously, bypassing the digestive system. However, it's always advisable to inform your doctor about your diet and any existing medical conditions.