ZAVAMET SR 1000 TABLET 10'S
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ZAVAMET SR 1000 TABLET 10'SZAVAMET SR 1000 TABLET 10'SZAVAMET SR 1000 TABLET 10'S
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ZAVAMET SR 1000 TABLET 10'S

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ZAVAMET SR 1000 TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

MRP

104.5

₹88.82

15 % OFF

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About ZAVAMET SR 1000 TABLET 10'S

  • ZAVAMET SR 1000 Tablet is a medication primarily used to manage blood sugar levels in individuals with type 2 diabetes. It belongs to the class of drugs known as biguanides, with its active ingredient being metformin. This sustained-release formulation ensures a gradual release of the medication, providing prolonged blood sugar control throughout the day and reducing the frequency of dosages.
  • Metformin, the key component of ZAVAMET SR 1000, works by improving the body's response to insulin, a natural hormone that regulates glucose levels. It achieves this by decreasing glucose production in the liver and enhancing insulin sensitivity in the muscles, enabling better glucose uptake and utilization. Additionally, metformin slows down the absorption of glucose from the intestines, further contributing to its blood sugar-lowering effects.
  • ZAVAMET SR 1000 is typically prescribed in conjunction with a healthy diet and regular exercise to achieve optimal glycemic control. Adhering to these lifestyle modifications is crucial for maximizing the benefits of the medication and improving overall health outcomes. The dosage of ZAVAMET SR 1000 is individualized based on the patient's blood sugar levels, kidney function, and other factors, as determined by their healthcare provider.
  • Patients taking ZAVAMET SR 1000 should be aware of potential side effects, which may include gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort. These side effects are usually mild and temporary, often subsiding as the body adjusts to the medication. However, in rare cases, metformin can cause a more serious condition called lactic acidosis, characterized by a buildup of lactic acid in the blood. Individuals with kidney problems, liver disease, or heart failure are at higher risk and should discuss this with their doctor. Regular monitoring of kidney function is recommended while taking this medicine.
  • ZAVAMET SR 1000 offers a convenient and effective way to manage type 2 diabetes, helping patients maintain stable blood sugar levels and reduce the risk of long-term complications associated with uncontrolled diabetes. It is essential to use this medicine under the guidance of a healthcare professional, who can provide personalized advice and monitor its effectiveness and safety.

Uses of ZAVAMET SR 1000 TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Management of polycystic ovary syndrome (PCOS)
  • Improving insulin sensitivity
  • Reducing the risk of heart disease (especially in patients with type 2 diabetes)
  • Aiding in weight management (in some patients)
  • Preventing the progression of prediabetes to type 2 diabetes

How ZAVAMET SR 1000 TABLET 10'S Works

  • ZAVAMET SR 1000 Tablet contains Metformin, a well-established medication used to manage blood sugar levels in individuals with type 2 diabetes. It belongs to a class of drugs called biguanides and works primarily by addressing insulin resistance and reducing glucose production in the liver.
  • Here's a detailed breakdown of how Metformin works: * **Reduces Hepatic Glucose Production:** The liver is a key player in glucose metabolism. It can produce glucose (sugar) and release it into the bloodstream, especially during fasting or between meals. Metformin acts on the liver to decrease the amount of glucose it produces. It achieves this by inhibiting gluconeogenesis (the process of creating glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen, a stored form of glucose). By reducing glucose production in the liver, Metformin helps lower fasting blood sugar levels.
  • * **Improves Insulin Sensitivity:** In type 2 diabetes, cells become resistant to the effects of insulin. This means that insulin, a hormone that helps glucose enter cells for energy, is less effective at lowering blood sugar levels. Metformin improves insulin sensitivity, allowing cells to respond more effectively to insulin. This enables glucose to enter cells more readily, lowering blood sugar levels after meals.
  • * **Slows Down Glucose Absorption in the Intestines:** Metformin can also slow down the absorption of glucose from the intestines into the bloodstream after a meal. This helps to prevent rapid spikes in blood sugar levels following food intake.
  • * **Other Potential Mechanisms:** While the above are the primary mechanisms, Metformin may also have other beneficial effects, such as improving lipid profiles (cholesterol and triglycerides) and promoting weight loss in some individuals. However, these effects are generally considered secondary to its blood sugar-lowering effects.
  • In summary, ZAVAMET SR 1000 Tablet works through multiple pathways to control blood sugar levels in type 2 diabetes. By reducing glucose production in the liver, improving insulin sensitivity, and slowing down glucose absorption, it helps to maintain stable blood sugar levels throughout the day. The 'SR' in ZAVAMET SR 1000 stands for Sustained Release, meaning the medication is released slowly into the body over an extended period. This helps to maintain a consistent level of the drug in the bloodstream and reduces the frequency of dosing, typically taken once or twice daily with meals, as directed by your doctor.
  • It's important to remember that ZAVAMET SR 1000 Tablet is most effective when used in conjunction with lifestyle modifications such as diet and exercise. It is also crucial to take the medication exactly as prescribed by your healthcare provider and to attend regular check-ups to monitor blood sugar levels and overall health.

Side Effects of ZAVAMET SR 1000 TABLET 10'SArrow

ZAVAMET SR 1000 TABLET 10'S can cause side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Some people may also experience a metallic taste in their mouth. Less common but potentially serious side effects include lactic acidosis (symptoms may include feeling very weak, tired or uncomfortable, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat), liver problems (symptoms may include yellowing of the skin or eyes), and vitamin B12 deficiency (symptoms may include fatigue, sore tongue, numbness/tingling in hands/feet). Allergic reactions such as rash, itching, or swelling are also possible. If you experience any unusual or severe side effects, it is important to contact your doctor immediately.

Safety Advice for ZAVAMET SR 1000 TABLET 10'SArrow

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Allergies

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Do not use ZAVAMET SR 1000 TABLET 10'S if you are allergic to it.

Dosage of ZAVAMET SR 1000 TABLET 10'SArrow

  • The recommended starting dosage of 'ZAVAMET SR 1000 TABLET 10'S' is typically one tablet (1000mg) once daily. This is usually taken with the evening meal to minimize gastrointestinal side effects. However, your doctor will determine the appropriate starting dose based on your individual needs and medical condition.
  • The dosage may be gradually increased by 500mg per day every week or two, up to a maximum of 2000mg per day, divided into two doses. The goal is to find the lowest dose that effectively controls your blood sugar levels without causing unacceptable side effects. It is crucial to follow your doctor’s instructions precisely regarding dosage adjustments.
  • For some individuals, a higher dosage may be necessary to achieve adequate glycemic control. In such cases, the maximum recommended daily dose is 3000mg, divided into three doses. However, this higher dosage should only be used under close medical supervision due to the increased risk of side effects.
  • It is vital to take 'ZAVAMET SR 1000 TABLET 10'S' with food to help prevent stomach upset. Swallow the tablets whole; do not crush or chew them. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Regular monitoring of your blood sugar levels is essential while taking 'ZAVAMET SR 1000 TABLET 10'S'. Your doctor may also recommend periodic blood tests to assess your kidney function, as 'ZAVAMET SR 1000 TABLET 10'S' is primarily eliminated by the kidneys. Inform your doctor about any other medications you are taking, as drug interactions can occur.
  • Take 'ZAVAMET SR 1000 TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of ZAVAMET SR 1000 TABLET 10'S?Arrow

  • If you miss a dose of ZAVAMET SR 1000 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store ZAVAMET SR 1000 TABLET 10'S?Arrow

  • Keep ZAVAMET SR 50/1000MG TAB 1X10 away from the reach of children and pets.
  • Store ZAVAMET SR 50/1000MG TAB 1X10 at room temperature.

Benefits of ZAVAMET SR 1000 TABLET 10'SArrow

  • ZAVAMET SR 1000 Tablet 10'S is primarily used to manage type 2 diabetes mellitus, a condition where the body doesn't use insulin properly, leading to elevated blood sugar levels. It helps improve glycemic control by reducing glucose production in the liver and enhancing insulin sensitivity in peripheral tissues. This dual action allows the body to utilize insulin more effectively, lowering blood sugar levels after meals and during fasting periods.
  • One of the key benefits of ZAVAMET SR 1000 is its ability to lower HbA1c levels. HbA1c provides an average measure of blood sugar control over the past 2-3 months. By consistently reducing blood glucose, ZAVAMET SR 1000 contributes to better long-term diabetes management and reduces the risk of diabetes-related complications.
  • ZAVAMET SR 1000 also helps in reducing the risk of cardiovascular events associated with diabetes. High blood sugar can damage blood vessels and increase the risk of heart disease, stroke, and peripheral artery disease. By maintaining healthy blood sugar levels, ZAVAMET SR 1000 aids in protecting the cardiovascular system.
  • Unlike some other diabetes medications, ZAVAMET SR 1000 generally does not cause weight gain. This is a significant advantage for individuals with type 2 diabetes who are often overweight or obese. Maintaining a healthy weight is crucial for managing diabetes and overall health.
  • ZAVAMET SR 1000 is often prescribed as a first-line treatment for type 2 diabetes due to its effectiveness and relatively low risk of side effects. It can be used alone or in combination with other diabetes medications to achieve optimal blood sugar control. Its extended-release formulation allows for once-daily dosing, improving patient compliance and convenience.
  • The medication also plays a role in preventing the progression of prediabetes to type 2 diabetes. For individuals with impaired glucose tolerance, ZAVAMET SR 1000 can help improve insulin sensitivity and reduce the likelihood of developing full-blown diabetes.
  • Furthermore, ZAVAMET SR 1000 has been shown to have positive effects on lipid profiles. It can help lower triglyceride levels and increase HDL (good) cholesterol levels, further contributing to cardiovascular health. These benefits make it a valuable component of a comprehensive diabetes management plan that includes diet, exercise, and regular monitoring.
  • ZAVAMET SR 1000's ability to improve insulin sensitivity means that the body's cells are more responsive to insulin's signal to absorb glucose from the bloodstream. This improved sensitivity helps to regulate blood sugar levels more effectively and reduces the strain on the pancreas to produce excessive amounts of insulin.
  • Another significant advantage is its impact on reducing the risk of diabetic nephropathy, or kidney damage caused by high blood sugar levels. By keeping blood glucose within a healthy range, ZAVAMET SR 1000 helps protect the kidneys from long-term damage and dysfunction.
  • ZAVAMET SR 1000 is a well-established and trusted medication with a proven track record in managing type 2 diabetes. Its multiple benefits, including blood sugar control, cardiovascular protection, and prevention of diabetes complications, make it an essential tool in the fight against this chronic condition.

How to use ZAVAMET SR 1000 TABLET 10'SArrow

  • ZAVAMET SR 1000 Tablet is a medication primarily used to manage blood sugar levels in individuals with type 2 diabetes. It's crucial to use this medication as directed by your healthcare provider. Typically, it's taken orally with meals to minimize gastrointestinal side effects. The 'SR' in the name stands for sustained-release, meaning the medication is released slowly into your system throughout the day.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can disrupt the sustained-release mechanism and potentially lead to a rapid and dangerous release of the drug. It's best to take ZAVAMET SR 1000 at the same time each day to maintain consistent blood sugar control.
  • The dosage is determined by your doctor based on your blood sugar levels, kidney function, and other medications you may be taking. It's important to adhere to the prescribed dosage and not to adjust it without consulting your doctor. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • During the course of taking ZAVAMET SR 1000, it's essential to monitor your blood sugar levels regularly as advised by your healthcare provider. This helps to ensure the medication is working effectively and allows for dosage adjustments if needed. You should also maintain a healthy diet and exercise regularly to optimize blood sugar control. Be aware of potential side effects such as nausea, diarrhea, or abdominal discomfort, and report any persistent or severe side effects to your doctor. Regular kidney function tests are also important while taking this medication.

Quick Tips for ZAVAMET SR 1000 TABLET 10'SArrow

  • Take ZAVAMET SR 1000 Tablet as prescribed by your doctor, usually once daily with your evening meal. This helps to minimize potential stomach upset and maximize the medication's effectiveness by ensuring a steady release of metformin throughout the night, controlling blood sugar levels while you sleep.
  • Maintain a consistent diet and exercise routine while taking ZAVAMET SR 1000 Tablet. Metformin works best when combined with lifestyle changes. Focus on incorporating regular physical activity, such as brisk walking or cycling, and a balanced diet rich in fiber, fruits, and vegetables. Avoid excessive consumption of sugary and processed foods.
  • Stay well-hydrated throughout the day. Drink plenty of water, as dehydration can sometimes mimic symptoms of high blood sugar. Adequate hydration also supports kidney function, which is important when taking metformin.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Keep a log of your blood sugar readings to share with your doctor during appointments.
  • Be aware of the potential side effects, such as nausea, diarrhea, or stomach discomfort, especially when starting ZAVAMET SR 1000 Tablet. These side effects are usually temporary and can be minimized by taking the medication with food. If side effects persist or worsen, consult your doctor. Report any unusual or severe symptoms immediately, especially signs of lactic acidosis (e.g., rapid breathing, severe muscle pain, unusual tiredness).
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Metformin can interact with other drugs, affecting its efficacy or increasing the risk of side effects. It's crucial to provide a complete list of all substances you are consuming to ensure your doctor can manage your treatment safely and effectively.
  • If you are scheduled for any surgery or medical procedure involving contrast dye, inform your doctor that you are taking ZAVAMET SR 1000 Tablet. You may need to temporarily discontinue the medication before the procedure to protect your kidneys.

Food Interactions with ZAVAMET SR 1000 TABLET 10'SArrow

  • ZAVAMET SR 1000 TABLET 10'S should be taken with food to decrease the chance of stomach upset.
  • Avoid excessive alcohol consumption while taking this medicine, as it can increase the risk of lactic acidosis, a serious side effect.
  • There are no specific foods that need to be avoided while taking ZAVAMET SR 1000 TABLET 10'S, but maintaining a balanced diet is always recommended.

FAQs

What is ZAVAMET SR 1000 Tablet used for?Arrow

ZAVAMET SR 1000 Tablet is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

How does ZAVAMET SR 1000 Tablet work?Arrow

ZAVAMET SR 1000 Tablet works by decreasing the amount of glucose produced by the liver, slowing down the absorption of glucose from the intestines, and improving the body's sensitivity to insulin.

What are the common side effects of ZAVAMET SR 1000 Tablet?Arrow

Common side effects of ZAVAMET SR 1000 Tablet include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is ZAVAMET SR 1000 Tablet safe for patients with kidney disease?Arrow

ZAVAMET SR 1000 Tablet should be used with caution in patients with kidney disease, as it may increase the risk of lactic acidosis. Consult your doctor for dose adjustments or consider an alternative medication.

Should ZAVAMET SR 1000 Tablet be taken with food?Arrow

ZAVAMET SR 1000 Tablet is generally recommended to be taken with food to minimize gastrointestinal side effects.

What to do if a dose of ZAVAMET SR 1000 Tablet is missed?Arrow

If you miss a dose of ZAVAMET SR 1000 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Is ZAVAMET SR 1000 Tablet safe during pregnancy?Arrow

The safety of ZAVAMET SR 1000 Tablet during pregnancy has not been established. It should only be used if the potential benefit outweighs the risk to the fetus. Consult your doctor.

How to store ZAVAMET SR 1000 Tablet?Arrow

Store ZAVAMET SR 1000 Tablet at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

Can ZAVAMET SR 1000 Tablet be taken with other medications?Arrow

ZAVAMET SR 1000 Tablet can interact with other medications. Tell your doctor about all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements.

What are the symptoms of an overdose of ZAVAMET SR 1000 Tablet?Arrow

Symptoms of an overdose of ZAVAMET SR 1000 Tablet may include nausea, vomiting, abdominal pain, fatigue, difficulty breathing, and lactic acidosis. Seek immediate medical attention if you suspect an overdose.

Does ZAVAMET SR 1000 Tablet cause weight gain?Arrow

ZAVAMET SR 1000 Tablet does not typically cause weight gain. In fact, some people may experience slight weight loss with it.

Can ZAVAMET SR 1000 Tablet be taken with alcohol?Arrow

Alcohol should be avoided while taking ZAVAMET SR 1000 Tablet, as it may increase the risk of lactic acidosis.

Is Metformin (the active ingredient in ZAVAMET SR 1000 Tablet) available under other brand names?Arrow

Yes, Metformin is available under various brand names. Some common brand names include Glucophage, Glucophage XR, and Fortamet.

How long does it take for ZAVAMET SR 1000 Tablet to start working?Arrow

It may take a few days for ZAVAMET SR 1000 Tablet to start lowering blood sugar levels. However, it may take several weeks to see the full effect of the medication.

Can ZAVAMET SR 1000 Tablet treat type 1 diabetes?Arrow

No, ZAVAMET SR 1000 Tablet is not used to treat type 1 diabetes. This medication is only for type 2 diabetes.

References

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FDA label for Metformin Hydrochloride Extended-Release Tablets. This document provides detailed information on the drug, including its uses, dosage, side effects, and interactions.

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DrugBank entry for Metformin. Comprehensive information on metformin's mechanism of action, pharmacokinetics, and therapeutic uses.

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Study on bioavailability of metformin from extended-release tablets under different food conditions

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European Medicines Agency (EMA) information on metformin-containing medicinal products. Provides regulatory information and scientific assessments.

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