NEBILONG AM TABLET 15'S

How NEBILONG AM TABLET 15'S Works

• NEBILONG AM TABLET 15'S is a combination medication containing Nebivolol and Amlodipine, designed to manage hypertension (high blood pressure). Each component contributes uniquely to lowering blood pressure, offering a synergistic effect for enhanced efficacy.
• Nebivolol is a beta-blocker that works primarily by selectively blocking beta-1 adrenergic receptors in the heart. This action reduces the heart rate and the force of heart muscle contraction, leading to a decrease in cardiac output and blood pressure. Additionally, Nebivolol stimulates the release of nitric oxide (NO) from the endothelial cells lining the blood vessels. Nitric oxide is a potent vasodilator, meaning it widens the blood vessels. This vasodilation further contributes to lowering blood pressure and improving blood flow.
• Amlodipine, on the other hand, is a calcium channel blocker. It works by inhibiting the influx of calcium ions into vascular smooth muscle cells and cardiac muscle cells. By blocking calcium channels in the smooth muscle of blood vessels, Amlodipine causes the blood vessels to relax and widen (vasodilation). This reduces peripheral vascular resistance, the resistance the heart has to pump against, ultimately lowering blood pressure. The relaxation of cardiac muscle cells also contributes to a reduction in blood pressure.
• The combination of Nebivolol and Amlodipine in NEBILONG AM TABLET 15'S provides a dual mechanism for blood pressure control. Nebivolol reduces cardiac output and increases vasodilation via nitric oxide, while Amlodipine directly vasodilates blood vessels by blocking calcium channels. This combined action effectively lowers blood pressure, making it easier for the heart to pump blood and reducing the workload on the cardiovascular system.
• Furthermore, by managing hypertension effectively, NEBILONG AM TABLET 15'S helps reduce the risk of serious complications associated with high blood pressure, such as stroke, heart attack, kidney problems, and other cardiovascular diseases. Regular use as prescribed by a healthcare professional, along with lifestyle modifications such as a healthy diet and regular exercise, is crucial for optimal blood pressure management and overall cardiovascular health.

Like all medicines, Nebilong AM Tablet can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Headache * Dizziness * Swelling of the ankles, feet, or fingers (edema) * Fatigue * Slow heart rate (bradycardia) * Diarrhea * Constipation **Uncommon side effects (may affect up to 1 in 100 people):** * Low blood pressure (hypotension) * Worsening of heart failure * Disturbed vision * Muscle cramps * Nausea * Indigestion * Skin rash or itching * Difficulty breathing (dyspnea) * Heart rhythm disturbances * Fluid retention * Weakness * Depression * Sleep disturbances **Rare side effects (may affect up to 1 in 1,000 people):** * Fainting * Worsening of psoriasis * Confusion **Very rare side effects (may affect up to 1 in 10,000 people):** * Angina pectoris **Other possible side effects (frequency not known):** * Allergic reactions (such as skin rash, itching, hives, swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing) * Erectile dysfunction * Dry mouth * Hair loss

• If you miss a dose of NEBILONG AM Tablet, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep NEBILONG AM TAB 1X15 away from the reach of children and pets.
• Store NEBILONG AM TAB 1X15 at room temperature.

• Take NEBILONG AM TABLET 15'S exactly as prescribed by your doctor. Do not exceed the recommended dosage or duration, as this can increase the risk of side effects. Typically, it is taken once daily, but your doctor will determine the most suitable schedule based on your specific needs and condition. Consistency is key; try to take it at the same time each day to maintain a steady level of medication in your system. This ensures optimal effectiveness in managing your blood pressure.
• NEBILONG AM TABLET 15'S is often more effective when combined with lifestyle modifications. These include adopting a heart-healthy diet that is low in sodium and saturated fats, engaging in regular physical activity such as brisk walking or cycling for at least 30 minutes most days of the week, and maintaining a healthy weight. It's also important to limit alcohol consumption and avoid smoking, as these can negatively impact your blood pressure and overall cardiovascular health. Regular monitoring of your blood pressure at home can help you and your doctor track your progress and make any necessary adjustments to your treatment plan.
• Be aware of potential side effects while taking NEBILONG AM TABLET 15'S. Common side effects may include dizziness, fatigue, headache, and swelling in the ankles or feet. Some individuals may also experience a slow heart rate or low blood pressure. If you experience any severe or persistent side effects, it's important to contact your doctor immediately. Do not discontinue the medication abruptly without consulting your healthcare provider, as this can lead to a sudden increase in blood pressure and other adverse effects. Your doctor can provide guidance on how to safely manage any side effects and make any necessary adjustments to your medication.
• Before starting NEBILONG AM TABLET 15'S, inform your doctor about any other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications can interact with NEBILONG AM TABLET 15'S, potentially affecting its effectiveness or increasing the risk of side effects. It's also important to disclose any underlying medical conditions you have, such as heart problems, kidney disease, or liver disease, as these may influence how your doctor prescribes the medication. Women who are pregnant or breastfeeding should also consult with their doctor before taking NEBILONG AM TABLET 15'S.
• Store NEBILONG AM TABLET 15'S in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. It's also important to check the expiration date on the packaging before taking the medication. If the medication has expired, do not use it and dispose of it properly according to local regulations. If you have any questions or concerns about how to store or dispose of NEBILONG AM TABLET 15'S, consult with your pharmacist or healthcare provider. Proper storage ensures the medication remains effective and safe for use.

• NEBILONG AM TABLET 15'S can be taken with or without food, but it is important to take it at the same time each day to maintain consistent blood levels of the medication. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medication, as it can increase the levels of amlodipine in your blood, potentially leading to increased side effects. If you have any specific dietary concerns or restrictions, discuss them with your doctor or pharmacist.