RITULASTA 500MG/50ML INJECTION
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RITULASTA 500MG/50ML INJECTION
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RITULASTA 500MG/50ML INJECTION

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RITULASTA 500MG/50ML INJECTION

By PLASMAGEN BIOSCIENCES PVT LTD

MRP

₹

14253

₹14253

10

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Composition

RITUXIMAB 500 MG

Product DetailsArrow

About RITULASTA 500MG/50ML INJECTION

  • Ritulasta 100mg injection contains the active ingredient rituximab and is prescribed for various conditions in adults. It is administered alone or alongside other medications for treating non-Hodgkin's lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, a common B-cell cancer. This injection is also indicated, in conjunction with methotrexate, for moderate-to-severe rheumatoid arthritis, where the immune system mistakenly attacks the body's joints. Furthermore, it is used in the treatment of granulomatosis with polyangiitis or microscopic polyangiitis, conditions characterized by blood vessel inflammation primarily affecting the lungs and kidneys in both adults and children aged 2 years and older. It also helps in treating moderate to severe pemphigus vulgaris, an autoimmune condition causing painful blisters on the skin, mouth, throat, nose, and genitals. RITULASTA 500MG/50ML INJECTION is a type of medication called anti-CD20 monoclonal antibodies. It works by targeting specific proteins on the surface of B-cells, which helps to reduce the activity of the immune system in autoimmune diseases and to eliminate cancerous B-cells in lymphoma and leukemia.
  • Do not use RITULASTA 500MG/50ML INJECTION if you have a known allergy to rituximab or any of the other ingredients in the injection. Avoid its use if you have a weakened immune system or a severe active infection. Before starting treatment, inform your doctor if you have any pre-existing heart conditions, heart failure, or breathing difficulties. It is crucial to discuss any prior history of hepatitis B infection with your doctor, as rituximab can sometimes reactivate the virus, potentially leading to severe complications. The use of this injection is generally not recommended during pregnancy and breastfeeding. Women of childbearing potential should use highly effective methods of contraception during treatment and for 12 months after the last dose to avoid pregnancy.
  • Common side effects of RITULASTA 500MG/50ML INJECTION may include blood infections, reduced red blood cell count, dizziness, facial and bodily swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (either low or high). It's important to use effective contraception during treatment and for 12 months after the last dose if you are able to become pregnant. This medicine may cause severe infusion reactions during or within 24 hours after administration. Immediately inform your doctor or healthcare professional if you experience any infusion-related reactions, such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling. The healthcare team will closely monitor you during and after the infusion to manage any potential reactions effectively. Remember to always consult with your doctor or healthcare provider for any concerns regarding your health or medication.

Uses of RITULASTA 500MG/50ML INJECTION

  • Non-Hodgkin's Lymphoma (NHL): A type of cancer that begins in the lymphatic system, affecting white blood cells called lymphocytes. RITULASTA 500MG/50ML INJECTION is used in its treatment.
  • Chronic Lymphocytic Leukemia (CLL): A type of cancer of the blood and bone marrow. RITULASTA 500MG/50ML INJECTION can be part of the treatment plan.
  • Rheumatoid Arthritis: An autoimmune disorder causing chronic inflammation of the joints. RITULASTA 500MG/50ML INJECTION may be prescribed to help manage symptoms and reduce inflammation.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: These are rare autoimmune diseases that cause inflammation of blood vessels. RITULASTA 500MG/50ML INJECTION is used to treat these conditions by suppressing the immune system.
  • Pemphigus Vulgaris: A rare autoimmune disease that causes blistering of the skin and mucous membranes. RITULASTA 500MG/50ML INJECTION is used to manage this condition by targeting the immune cells that cause the blistering.

Side Effects of RITULASTA 500MG/50ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, although not everyone experiences them. RITULASTA 500MG/50ML INJECTION can cause both common and serious side effects.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for RITULASTA 500MG/50ML INJECTIONArrow

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Pregnancy

UNSAFE

RITULASTA 500MG/50ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of RITULASTA 500MG/50ML INJECTIONArrow

  • RITULASTA 500MG/50ML INJECTION is a medication that must be administered exclusively by a qualified healthcare professional, such as a trained doctor or nurse. Self-administration is strictly prohibited. Prior to receiving RITULASTA 500MG/50ML INJECTION, you will be administered premedications to mitigate potential side effects and ensure your comfort during the infusion.
  • The dosage and duration of your treatment will be determined by your doctor, taking into account the severity of your condition and other relevant health factors. This personalized approach ensures that you receive the most effective treatment tailored to your specific needs.
  • RITULASTA 500MG/50ML INJECTION will be administered as an intravenous infusion, allowing the medication to be delivered directly into your bloodstream for optimal absorption and efficacy. Throughout the infusion process, you will be under close observation by medical personnel to monitor for any adverse reactions or unwanted side effects. This vigilant monitoring ensures your safety and well-being during the treatment.

How to store RITULASTA 500MG/50ML INJECTION?Arrow

  • Keep RITULASTA 500MG INJ 50ML away from the reach of children and pets.
  • Store RITULASTA 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RITULASTA 500MG/50ML INJECTIONArrow

  • RITULASTA 500MG/50ML INJECTION is a specialized medication containing a monoclonal antibody designed to target the CD20 antigen found on the surface of B-lymphocytes, which are a type of white blood cell. In the context of Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), this injection works by attaching itself to these B-cells and triggering cell death, effectively reducing the population of cancerous cells. This targeted action is crucial in managing these conditions. The binding mechanism also plays a role in preventing B-cell activation and growth, leading to significant anticancer effects, further inhibiting the progression of NHL and CLL.
  • In addition to its use in cancer treatment, RITULASTA 500MG/50ML INJECTION demonstrates efficacy in managing rheumatoid arthritis. It achieves this by inhibiting several key processes involved in the disease's pathology. These include the reduction of rheumatoid factor production, hindering antigen presentation, suppressing T-cell activation, and decreasing the production of pro-inflammatory cytokines. By modulating these immune responses, the injection helps alleviate the symptoms and slow the progression of rheumatoid arthritis, providing relief to patients suffering from this chronic condition.
  • The dual action of RITULASTA 500MG/50ML INJECTION, targeting both cancerous B-cells in NHL and CLL and modulating immune responses in rheumatoid arthritis, underscores its versatility and importance in treating these distinct yet debilitating conditions. Its ability to selectively induce cell death in cancerous lymphocytes and dampen the inflammatory cascade in autoimmune disorders makes it a valuable therapeutic option for patients. Always consult with your healthcare provider.

How to use RITULASTA 500MG/50ML INJECTIONArrow

  • RITULASTA 500MG/50ML INJECTION administration should strictly be performed by a qualified healthcare professional, such as a trained doctor or nurse. Self-administration is strictly prohibited. Prior to receiving RITULASTA 500MG/50ML INJECTION, it is common practice to administer pre-medications to mitigate potential side effects. These pre-medications help to prepare your body for the infusion and reduce the likelihood of adverse reactions.
  • The dosage and duration of your treatment will be determined by your doctor, taking into account the severity of your condition and other relevant individual factors. It is crucial to adhere to the prescribed dosage and treatment schedule for optimal results.
  • RITULASTA 500MG/50ML INJECTION is administered as an intravenous infusion, meaning it is delivered directly into your vein. During the infusion process, you will be under close observation by healthcare professionals who will monitor you carefully for any signs of unwanted side effects or adverse reactions. This close monitoring ensures your safety and allows for prompt intervention if needed. This meticulous approach ensures that you receive the medication safely and effectively, maximizing its therapeutic benefits while minimizing potential risks.

FAQs

What are the special precautions I should be aware of before starting treatment with RITULASTA 100MG/50ML INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are RITULASTA 100MG/50ML INFUSION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering RITULASTA 100MG/50ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during RITULASTA 100MG/50ML INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the RITULASTA 100MG/50ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of RITULASTA 100MG/50ML INJECTION?Arrow

Weight gain has been reported in patients treated with RITULASTA 100MG/50ML INJECTION for non-hodgkin’s lymphoma.

Does RITULASTA 100MG/50ML INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking RITULASTA 100MG/50ML INJECTION because it may cause drug-induced immunosuppression.

Are there any interactions of RITULASTA 500MG/50ML INJECTION with other drugs?Arrow

NULL interaction of RITULASTA 500MG/50ML INJECTION with other drungs

What advice should I follow while taking RITULASTA 500MG/50ML INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because RITULASTA 100MG/50ML INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making RITULASTA 500MG/50ML INJECTION?Arrow

RITUXIMAB is molecule/combination used for making RITULASTA 500MG/50ML INJECTION.

For which ailments/diseases/conditions is RITULASTA 500MG/50ML INJECTION prescribed?Arrow

RITULASTA 500MG/50ML INJECTION is prescribed for ailments related to Oncology, Gastroenterology, Rheumatology, and Orthopaedics.

Is RITULASTA 500MG/50ML INJECTION prescribed for Rheumatoid Arthritis?Arrow

Yes, RITULASTA 500MG/50ML INJECTION is prescribed for treating Rheumatoid Arthritis as it falls under Rheumatology.

References

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HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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અસ્વીકરણ

અહીંની કન્ટેન્ટ માત્ર માહિતીના હેતુઓ માટે છે અને વ્યાવસાયિક તબીબી સલાહ, નિદાન અથવા સારવારનો વિકલ્પ બનવાનો હેતુ નથી. તબીબી સ્થિતિને લગતા કોઈપણ પ્રશ્નો માટે કૃપા કરીને ચિકિત્સક અથવા અન્ય યોગ્ય આરોગ્ય પ્રદાતાની સલાહ લો. કોઈપણ માહિતી અને અનુગામી ક્રિયા અથવા નિષ્ક્રિયતા પર મેડકાર્ટ ફક્ત વપરાશકર્તાના જોખમ પર છે, અને અમે તેના માટે કોઈ જવાબદારી લેતા નથી. પ્લેટફોર્મ પરનો કન્ટેન્ટ વ્યાવસાયિક અને યોગ્ય તબીબી સલાહના વિકલ્પ તરીકે ધ્યાનમાં લેવી જોઈએ નહીં અથવા તેનો ઉપયોગ કરવો જોઈએ નહીં.દવાઓ, પરીક્ષણો અને/અથવા રોગોને લગતી કોઈપણ પ્રશ્ન માટે કૃપા કરીને તમારા ડૉક્ટરની સલાહ લો, કારણ કે અમે સમર્થન આપીએ છીએ, અને ડૉક્ટર-દર્દી સંબંધને બદલશો નહીં.

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