RITUXY 500 INJECTION
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RITUXY 500 INJECTION
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RITUXY 500 INJECTION

By GLENMARK PHARMACEUTICALS LIMITED

MRP

₹

43720

₹10605

75.74 % OFF

10

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Medicine Composition Icon

Composition

RITUXIMAB 500 MG

Product DetailsArrow

About RITUXY 500 INJECTION

  • RITUXY 500 INJECTION contains the active ingredient rituximab and is prescribed for various conditions in adults. It is administered alone or in combination with other medications to treat non-Hodgkin's lymphoma, a cancer affecting white blood cells known as B-lymphocytes, and chronic lymphocytic leukemia, a common cancer affecting B-cells. This injection is also used in conjunction with methotrexate to treat moderate-to-severe rheumatoid arthritis, a disease where the immune system mistakenly attacks joint tissues. RITUXY 500 INJECTION is further indicated for treating granulomatosis with polyangiitis and microscopic polyangiitis, conditions causing blood vessel inflammation primarily affecting the lungs and kidneys, in both adults and children aged two years and older. It also addresses moderate to severe pemphigus vulgaris, an autoimmune disorder characterized by painful blisters on the skin, mouth lining, throat, nose, and genitals.
  • RITUXY 500 INJECTION belongs to the anti-CD20 monoclonal antibodies drug class. Avoid this injection if you have a known allergy to rituximab or any of its components, have a weakened immune system, or are currently experiencing a severe active infection. Before starting treatment, inform your doctor about any pre-existing heart conditions, heart failure, or breathing difficulties. It's crucial to discuss any prior hepatitis B infection with your doctor, as rituximab can reactivate the virus in some instances, potentially leading to severe complications. It is generally not recommended to use RITUXY 500 INJECTION during pregnancy or breastfeeding due to potential risks to the fetus or infant.
  • Common side effects associated with RITUXY 500 INJECTION include blood infections, reduced red blood cell count, dizziness, facial and bodily swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (both low and high). If you are capable of becoming pregnant, it's essential to use effective contraception during treatment and for 12 months following the last dose. This medication carries the risk of severe infusion reactions, which may occur during or within 24 hours after administration. Immediately notify your physician or healthcare professional if you experience any signs of an infusion reaction, such as elevated blood pressure, chest pain, headache, breathing problems, vomiting, skin rashes, or throat swelling. Regular monitoring and prompt intervention are crucial to manage any potential adverse effects.
  • RITUXY 500 INJECTION works by targeting a protein called CD20, which is found on B-lymphocytes. By binding to CD20, rituximab helps to eliminate these cells, which are often implicated in autoimmune diseases and certain cancers. The dosage and frequency of administration will depend on the specific condition being treated and the individual's response to the medication. It's important to adhere to the prescribed treatment plan and attend all scheduled appointments for monitoring and evaluation.
  • In addition to its approved uses, RITUXY 500 INJECTION is sometimes used off-label for other conditions where B-cell depletion may be beneficial. The decision to use rituximab in these cases is made by the physician based on their clinical judgment and assessment of the potential risks and benefits. Patients should always discuss the potential risks and benefits of RITUXY 500 INJECTION with their healthcare provider before starting treatment.

Uses of RITUXY 500 INJECTION

  • Non-Hodgkin's lymphoma (NHL) which is a type of cancer that begins in the lymphatic system. This system is part of the immune system, which protects the body from infection and disease.
  • Chronic lymphocytic leukemia (CLL), a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell).
  • Rheumatoid Arthritis, a chronic inflammatory disorder affecting many joints, including those in the hands and feet.
  • Granulomatosis with polyangiitis or microscopic polyangiitis, rare diseases that cause inflammation of blood vessels.
  • Pemphigus vulgaris, a rare autoimmune disease that causes painful blisters on the skin and mucous membranes.

Side Effects of RITUXY 500 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for RITUXY 500 INJECTIONArrow

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Pregnancy

UNSAFE

RITUXY 500 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of RITUXY 500 INJECTIONArrow

  • RITUXY 500 INJECTION must be administered by a trained doctor or nurse. Self-administration is strictly prohibited. Prior to receiving RITUXY 500 INJECTION, you will be given pre-medications to minimize potential side effects. These pre-medications may include antihistamines, pain relievers, and/or corticosteroids, which help to prevent or reduce infusion-related reactions. Your doctor will determine the appropriate dosage and duration of treatment based on the severity of your condition, your overall health, and other individual factors. This ensures that you receive the most effective treatment tailored to your specific needs.
  • RITUXY 500 INJECTION will be administered as an intravenous infusion, allowing the medication to enter your bloodstream directly. During the infusion, you will be closely monitored for any adverse reactions or side effects. The healthcare professionals administering the injection are trained to recognize and manage any potential complications that may arise. Regular monitoring ensures your safety and allows for immediate intervention if necessary.
  • It is crucial to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking before starting treatment with RITUXY 500 INJECTION. This information helps your doctor to assess the risks and benefits of the treatment and to make informed decisions about your care. Your cooperation in providing accurate and complete information is essential for ensuring the safe and effective use of RITUXY 500 INJECTION.

How to store RITUXY 500 INJECTION?Arrow

  • Keep RITUXY 500MG INJ 50ML away from the reach of children and pets.
  • Store RITUXY 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RITUXY 500 INJECTIONArrow

  • RITUXY 500 INJECTION is a targeted medication designed to treat specific conditions by focusing on B-lymphocytes, a type of white blood cell. It contains a monoclonal antibody that zeroes in on the CD20 antigen present on the surface of these cells.
  • In Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), RITUXY 500 INJECTION binds to the B-cells, triggering cell death and helping to reduce the number of cancerous cells. This mechanism of action helps to control the progression of these diseases.
  • The binding action of RITUXY 500 INJECTION also plays a crucial role in preventing cell activation and growth, leading to anticancer effects. By blocking these processes, the medication helps to slow down the spread of cancer.
  • In the context of rheumatoid arthritis, RITUXY 500 INJECTION works by inhibiting rheumatoid factor production, antigen presentation, T-cell activation, and the production of pro-inflammatory cytokines. This helps to reduce inflammation and alleviate symptoms associated with the condition.
  • Overall, RITUXY 500 INJECTION offers a targeted approach to managing conditions affecting B-lymphocytes, whether in the context of cancer or autoimmune disorders, by modulating the activity and quantity of these cells within the body.

How to use RITUXY 500 INJECTIONArrow

  • RITUXY 500 INJECTION should only be administered by a trained doctor or nurse. Self-administration is strictly prohibited. Prior to receiving RITUXY 500 INJECTION, you will be given premedications to help minimize potential side effects. These premedications might include antihistamines or corticosteroids, which help to prevent or lessen infusion reactions.
  • The dosage and duration of your treatment will be determined by your doctor, taking into account the severity of your condition, your overall health, and response to the medication. It's crucial to adhere to the prescribed treatment plan for optimal results.
  • RITUXY 500 INJECTION is administered as an intravenous infusion, meaning it is delivered directly into your vein over a specific period of time. During the infusion, you will be closely monitored by healthcare professionals for any adverse reactions or unwanted side effects. This allows for immediate intervention if any issues arise. The healthcare team will regularly check your vital signs, such as blood pressure, heart rate, and temperature, to ensure your safety and comfort throughout the procedure.
  • It is crucial to inform your doctor about all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, as these may interact with RITUXY 500 INJECTION.

FAQs

What are the special precautions I should be aware of before starting treatment with RITUXY 500 INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are RITUXY 500 INJECTION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering RITUXY 500 INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomiting, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during RITUXY 500 INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the RITUXY 500 INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Does RITUXY 500 INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking RITUXY 500 INJECTION because it may cause drug-induced immunosuppression.

Is weight gain a side effect of RITUXY 500 INJECTION?Arrow

Weight gain has been reported in patients treated with RITUXY 500 INJECTION for non-hodgkin’s lymphoma.

Is there any interaction of RITUXY 500 INJECTION with other drugs?Arrow

There is NULL interaction of RITUXY 500 INJECTION with other drungs

What advice should I take while taking RITUXY 500 INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because RITUXY 500 INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

What molecule/combination is used for making RITUXY 500 INJECTION?Arrow

RITUXIMAB is molecule/combination used for making RITUXY 500 INJECTION.

For which ailments/diseases/conditions RITUXY 500 INJECTION is prescribed?Arrow

RITUXY 500 INJECTION is prescribed for Oncology, Gastroenterology, Rheumatology, Orthopaedics ailments/diseases/conditions.

Is RITUXY 500 INJECTION used for Rheumatology?Arrow

Yes, RITUXY 500 INJECTION is used for Rheumatology.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Nice experience, always!

Ashutosh Buch

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Reviewed on 24-02-2023

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(5/5)

People who works there are just amazing very friendly and supportive

Daxesh Patel

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Reviewed on 15-02-2024

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(5/5)

Visited medkart and it was a great experience with staff and they explains everything about generic medicine. How they r less in cost and both continent and power are same., everyone who buy their monthly medicine from other medicine stores should visit medkart and convert to generic medicine........ Best of luck medkart

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Reviewed on 19-04-2023

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DD Sanghavi

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Reviewed on 14-07-2023

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(3/5)

Best cooperation

Chirag Patel

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Reviewed on 01-02-2024

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(5/5)

Marketer / Manufacturer Details

GLENMARK PHARMACEUTICALS LIMITED

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India

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અસ્વીકરણ

અહીંની કન્ટેન્ટ માત્ર માહિતીના હેતુઓ માટે છે અને વ્યાવસાયિક તબીબી સલાહ, નિદાન અથવા સારવારનો વિકલ્પ બનવાનો હેતુ નથી. તબીબી સ્થિતિને લગતા કોઈપણ પ્રશ્નો માટે કૃપા કરીને ચિકિત્સક અથવા અન્ય યોગ્ય આરોગ્ય પ્રદાતાની સલાહ લો. કોઈપણ માહિતી અને અનુગામી ક્રિયા અથવા નિષ્ક્રિયતા પર મેડકાર્ટ ફક્ત વપરાશકર્તાના જોખમ પર છે, અને અમે તેના માટે કોઈ જવાબદારી લેતા નથી. પ્લેટફોર્મ પરનો કન્ટેન્ટ વ્યાવસાયિક અને યોગ્ય તબીબી સલાહના વિકલ્પ તરીકે ધ્યાનમાં લેવી જોઈએ નહીં અથવા તેનો ઉપયોગ કરવો જોઈએ નહીં.દવાઓ, પરીક્ષણો અને/અથવા રોગોને લગતી કોઈપણ પ્રશ્ન માટે કૃપા કરીને તમારા ડૉક્ટરની સલાહ લો, કારણ કે અમે સમર્થન આપીએ છીએ, અને ડૉક્ટર-દર્દી સંબંધને બદલશો નહીં.

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