SITAHENZ M OD TABLET 10'S

How SITAHENZ M OD TABLET 10'S Works

• SITAHEZ M OD Tablet 10's is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Sitagliptin and Metformin Hydrochloride. Each component works through distinct mechanisms to improve glycemic control.
• **Sitagliptin's Mechanism:** Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood glucose levels are high and suppress glucagon secretion from the pancreas when blood glucose levels are low. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones in the body. This leads to enhanced insulin secretion (in a glucose-dependent manner), reduced glucagon secretion, and ultimately, lower blood sugar levels after meals.
• **Metformin's Mechanism:** Metformin is a biguanide that primarily works by reducing glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process by which the liver generates glucose from non-carbohydrate sources. Additionally, metformin enhances insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. Metformin may also slightly slow down the absorption of glucose from the intestines. Unlike some other diabetes medications, metformin does not typically cause hypoglycemia (low blood sugar) when used alone because it doesn't directly stimulate insulin release.
• **Synergistic Action:** The combination of sitagliptin and metformin offers a synergistic approach to managing blood sugar. Sitagliptin enhances insulin secretion and suppresses glucagon, while metformin reduces glucose production and improves insulin sensitivity. Together, they provide more comprehensive glycemic control than either drug could achieve alone. The 'OD' in the name stands for Once Daily, hence promoting convenience and compliance.
• In summary, SITAHEZ M OD Tablet 10's helps to regulate blood sugar levels by improving insulin secretion, suppressing glucagon release, reducing glucose production in the liver, and enhancing insulin sensitivity in peripheral tissues. This multi-pronged approach makes it an effective treatment option for managing type 2 diabetes, when used in conjunction with diet and exercise.

Common side effects of SITAHENZ M OD Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are headache, dizziness, constipation, upper respiratory tract infection, and skin reactions like rash or itching. Uncommon but potentially serious side effects could involve pancreatitis, severe allergic reactions (anaphylaxis), liver problems (hepatitis), kidney problems, lactic acidosis (build-up of lactic acid in the blood), and vitamin B12 deficiency with long-term use. If you experience any persistent or severe side effects, discontinue use and consult your doctor immediately.

• If you miss a dose of SITAHENZ M OD TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITAHENZ M OD TAB 1X10 away from the reach of children and pets.
• Store SITAHENZ M OD TAB 1X10 at room temperature.

• Take SITAHENZ M OD TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting them, as this could affect your blood sugar levels.
• SITAHENZ M OD TABLET 10'S is usually taken once daily, preferably with your evening meal. This helps to maximize its effectiveness in controlling blood sugar levels throughout the night and morning.
• Monitor your blood sugar levels regularly as directed by your healthcare provider. Keep a record of your readings and share it with your doctor during your appointments. This helps in assessing how well the medication is working for you and if any adjustments are needed. Regular blood sugar monitoring is crucial for managing diabetes effectively and preventing complications. Discuss any unusual or concerning blood sugar readings with your doctor promptly. Make sure that you also monitor HbA1c regularly as prescribed by your doctor for better management
• Follow a balanced diet and exercise regularly while taking SITAHENZ M OD TABLET 10'S. Combining medication with lifestyle changes significantly improves blood sugar control and overall health. A diet rich in fiber, whole grains, and lean protein, along with regular physical activity, can enhance the effectiveness of the medication and help you maintain a healthy weight. Consult with a registered dietitian or certified diabetes educator for personalized guidance on diet and exercise plans tailored to your specific needs.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or juice, with you at all times. If you experience these symptoms, consume the fast-acting sugar immediately and check your blood sugar levels. If your blood sugar remains low, seek medical attention promptly. It's also important to inform your family and friends about the signs of hypoglycemia and how to assist you in case of an emergency. Always consult your doctor, if you experience any side effects after taking the medicine.

• SITAHENZ M OD TABLET 10'S is generally safe to take with food. However, it is important to follow your doctor's instructions regarding diet and meal timings while taking this medication. Consistent meal timings can help maintain stable blood sugar levels. If you experience any stomach upset, taking it with food might help.