SITAXA M XR 100MG/1000MG TABLET 10'S

How SITAXA M XR 100MG/1000MG TABLET 10'S Works

• SITAXA M XR 100MG/1000MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: sitagliptin and metformin hydrochloride. Each component works through distinct yet complementary mechanisms to achieve optimal glycemic control.
• Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood glucose levels are high and suppress glucagon secretion, which reduces glucose production by the liver. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones in the body. This results in enhanced insulin secretion in response to meals and decreased glucagon secretion, leading to lower post-meal blood glucose spikes and improved overall glycemic control. Sitagliptin's action is glucose-dependent, meaning it primarily works when blood sugar is elevated, reducing the risk of hypoglycemia (low blood sugar).
• Metformin hydrochloride, on the other hand, is a biguanide. Its primary mechanism of action is to decrease glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Additionally, metformin improves insulin sensitivity in peripheral tissues, such as muscle and fat, allowing these tissues to utilize glucose more effectively. This enhanced glucose uptake further contributes to lower blood sugar levels. Metformin also slows down the absorption of glucose from the intestines, which helps to reduce post-meal glucose surges. Unlike some other diabetes medications, metformin does not directly stimulate insulin release, minimizing the risk of hypoglycemia when used alone. The 'XR' in SITAXA M XR stands for extended-release, meaning the medication is released slowly into the body over a longer period. This helps to maintain more consistent blood sugar control throughout the day and often reduces the frequency of dosing compared to immediate-release formulations.
• In combination, sitagliptin and metformin address multiple aspects of glucose regulation. Sitagliptin enhances insulin secretion and reduces glucagon, while metformin reduces hepatic glucose production, improves insulin sensitivity, and slows intestinal glucose absorption. This synergistic effect leads to more effective blood sugar control than either medication could achieve alone. The extended-release formulation of SITAXA M XR provides convenient once-daily dosing for many patients, improving adherence to the treatment plan and contributing to better long-term outcomes in managing type 2 diabetes. Always take SITAXA M XR as prescribed by your doctor, and follow their recommendations regarding diet and exercise for optimal management of your diabetes.

Common side effects of SITAXA M XR 100MG/1000MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are headache, dizziness, constipation, upper respiratory tract infection, and back pain. Less common but potentially serious side effects include pancreatitis, severe allergic reactions (rash, itching, swelling), lactic acidosis, and liver problems. Contact your doctor immediately if you experience persistent or severe side effects.

• If you miss a dose of SITAXA M XR, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for the missed one.

• Keep SITAXA M XR 100/1000MG TAB 1X10 away from the reach of children and pets.
• Store SITAXA M XR 100/1000MG TAB 1X10 at room temperature.

• **Take with Food:** To minimize stomach upset, always take SITAXA M XR with a meal. This helps your body absorb the medication effectively and reduces the risk of nausea or digestive discomfort. Consistent timing with meals is key for optimal results.
• **Follow Dosage Instructions Precisely:** Adhere strictly to your doctor's prescribed dosage and timing. Do not crush, chew, or break the tablet. Swallow it whole with water. Altering the tablet's form can affect how the medication is released into your system, potentially leading to inconsistent blood sugar control. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose; in that case, skip the missed dose and continue with your regular schedule. Never double your dose to compensate for a missed one.
• **Monitor Blood Sugar Regularly:** Regularly monitor your blood sugar levels as directed by your healthcare provider. Keep a log of your readings and share it with your doctor during check-ups. This helps them assess the effectiveness of the medication and make any necessary adjustments to your treatment plan. Understanding how SITAXA M XR affects your blood sugar levels empowers you to manage your diabetes more effectively.
• **Stay Hydrated:** Drink plenty of water throughout the day. Staying hydrated is crucial for overall health and helps your kidneys function properly, especially when taking medications like SITAXA M XR. Adequate hydration aids in flushing out waste products and maintaining healthy blood sugar levels.
• **Inform Your Doctor About Other Medications:** Before starting SITAXA M XR, inform your doctor about all other medications, supplements, and herbal remedies you are taking. Certain medications can interact with SITAXA M XR, affecting its efficacy or increasing the risk of side effects. Your doctor needs a complete picture of your medication regimen to ensure your safety and optimize your treatment.
• **Be Aware of Hypoglycemia Symptoms:** SITAXA M XR can sometimes cause hypoglycemia (low blood sugar). Be aware of the symptoms, which may include shakiness, sweating, dizziness, confusion, rapid heartbeat, and hunger. If you experience these symptoms, consume a fast-acting source of sugar, such as fruit juice, glucose tablets, or hard candy, and check your blood sugar levels. Consult your doctor if you experience frequent or severe episodes of hypoglycemia.
• **Maintain a Healthy Lifestyle:** SITAXA M XR works best when combined with a healthy lifestyle. Follow a balanced diet, engage in regular physical activity, and maintain a healthy weight. These lifestyle modifications can significantly improve your blood sugar control and overall health. Consult with a registered dietitian or certified diabetes educator for personalized guidance on diet and exercise.