SITARA DM 10/100/1000MG TABLET 10'S

How SITARA DM 10/100/1000MG TABLET 10'S Works

• SITARA DM 10/100/1000MG TABLET 10'S is a combination medication designed to manage diabetes mellitus effectively. It leverages the synergistic action of three key ingredients: Sitagliptin, Metformin, and Vitamin D3 (Cholecalciferol). Understanding how each component works is crucial to appreciating the overall therapeutic benefit of this medication.
• **Sitagliptin (10mg):** Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 enzymes break down incretin hormones in the body. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a vital role in regulating blood sugar levels. They stimulate insulin release from the pancreas when blood glucose is high and suppress glucagon secretion (a hormone that raises blood sugar) from the pancreas when blood glucose is low. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This leads to improved insulin secretion in response to meals and reduced glucagon secretion, ultimately helping to lower blood sugar levels, particularly after eating.
• **Metformin (100mg):** Metformin is a biguanide antihyperglycemic agent. It works primarily by reducing glucose production in the liver (hepatic gluconeogenesis). It achieves this by activating an enzyme called AMPK (AMP-activated protein kinase), which plays a key role in cellular energy metabolism. By activating AMPK, metformin inhibits the liver's ability to produce glucose. Additionally, Metformin improves insulin sensitivity in peripheral tissues (such as muscles), allowing them to utilize glucose more effectively. It also slows down the absorption of glucose from the intestines. Unlike some other diabetes medications, metformin, when used alone, does not typically cause hypoglycemia (low blood sugar).
• **Vitamin D3 (Cholecalciferol 1000mg):** Vitamin D3, also known as cholecalciferol, is a fat-soluble vitamin that plays a crucial role in calcium and phosphate metabolism, promoting bone health. Emerging research suggests that Vitamin D3 may also play a role in insulin sensitivity and glucose metabolism. Vitamin D deficiency has been linked to an increased risk of insulin resistance and type 2 diabetes. Vitamin D3 helps to improve insulin sensitivity and glycemic control.
• In summary, SITARA DM 10/100/1000MG TABLET 10'S works through a multi-pronged approach: Sitagliptin enhances incretin activity to boost insulin release and reduce glucagon secretion; Metformin reduces liver glucose production, improves insulin sensitivity, and reduces intestinal glucose absorption; and Vitamin D3 potentially helps with insulin sensitivity and glucose metabolism. This combination helps to regulate blood sugar levels effectively in patients with type 2 diabetes mellitus, particularly when diet and exercise alone are not sufficient. Always take SITARA DM 10/100/1000MG TABLET 10'S exactly as prescribed by your doctor, and be aware of potential side effects and interactions with other medications.

Common side effects of SITARA DM may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and skin rash. Less common but potentially serious side effects include lactic acidosis (symptoms: weakness, muscle pain, trouble breathing, stomach pain), hypoglycemia (symptoms: sweating, shaking, anxiety, blurred vision), and liver problems (symptoms: yellowing of skin/eyes, dark urine, persistent nausea). Allergic reactions (rash, itching, swelling), vitamin B12 deficiency (symptoms: numbness, tingling, sore tongue), and rarely, blood disorders may also occur. Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of SITARA DM 10/100/1000MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITARA DM 10/100/1000MG TAB 1X10 away from the reach of children and pets.
• Store SITARA DM 10/100/1000MG TAB 1X10 at room temperature.

• Take SITARA DM 10/100/1000MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. Consistent adherence to the prescribed regimen optimizes its effectiveness in managing your condition.
• Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed in your body, potentially altering its efficacy.
• Maintain a consistent daily schedule for taking SITARA DM 10/100/1000MG TABLET 10'S. Taking it at the same time each day helps maintain a steady level of medication in your bloodstream, maximizing its therapeutic benefits. You can set a daily alarm to remind you.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking. Drug interactions can occur, potentially affecting how SITARA DM 10/100/1000MG TABLET 10'S works or increasing the risk of side effects. This includes both prescription and over-the-counter products.
• Monitor your blood sugar levels regularly as directed by your healthcare provider. SITARA DM 10/100/1000MG TABLET 10'S helps manage blood sugar, and regular monitoring allows you to track your progress and make necessary adjustments to your diet and exercise routine, in consultation with your doctor.
• Be aware of potential side effects, such as nausea, diarrhea, or headache. While not everyone experiences these, knowing them allows you to address them promptly. Contact your doctor if you experience any severe or persistent side effects. Mild side effects often resolve on their own as your body adjusts to the medication.
• Store SITARA DM 10/100/1000MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Proper storage helps maintain the integrity and effectiveness of the medication. Keep it out of reach of children and pets to prevent accidental ingestion.
• Follow a healthy diet and exercise regularly while taking SITARA DM 10/100/1000MG TABLET 10'S. Medication works best when combined with lifestyle modifications. A balanced diet and regular physical activity can significantly improve your overall health and help manage your condition more effectively.
• Attend all scheduled follow-up appointments with your doctor. These appointments are crucial for monitoring your progress, adjusting your treatment plan if necessary, and addressing any concerns or questions you may have. Regular check-ups ensure that you receive the best possible care.
• If you miss a dose of SITARA DM 10/100/1000MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• SITARA DM 10/100/1000MG TABLET 10'S can generally be taken with or without food, but it's best to take it at the same time each day to maintain consistent blood sugar levels. However, if you experience stomach upset, taking it with food may help. Avoid excessive alcohol consumption as it can interfere with blood sugar control and increase the risk of side effects.