SITAZIT DM 10/100/1000 TABLET 10'S

How SITAZIT DM 10/100/1000 TABLET 10'S Works

• SITAZIT DM 10/100/1000 Tablet is a combination medication designed to manage type 2 diabetes mellitus. It combines three active ingredients: Sitagliptin, Metformin, and a third component that varies depending on the specific strength (either another dose of Metformin or a different drug class). Understanding how each component works is crucial to appreciating the overall effectiveness of SITAZIT DM.
• **Sitagliptin:** Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a vital role in regulating blood sugar levels. They stimulate the release of insulin from the pancreas when blood sugar is high and suppress the release of glucagon, a hormone that raises blood sugar levels. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones. This, in turn, enhances insulin secretion in response to high blood sugar and reduces glucagon secretion, leading to better blood sugar control.
• **Metformin:** Metformin is a biguanide that works primarily by reducing glucose production in the liver. It also improves insulin sensitivity in the body's tissues, allowing cells to use glucose more effectively. Specifically, Metformin: * Decreases hepatic glucose production: Metformin reduces the amount of glucose produced by the liver, which is a major source of glucose in the body, especially during fasting. * Increases insulin sensitivity: Metformin makes the body's cells more responsive to insulin, allowing them to take up glucose from the bloodstream more efficiently. * Decreases intestinal glucose absorption: Metformin may also slightly reduce the absorption of glucose from the intestines after a meal.
• **Combined Action:** The combined action of Sitagliptin and Metformin provides a multi-pronged approach to managing blood sugar levels in type 2 diabetes. Sitagliptin enhances insulin secretion and reduces glucagon levels, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This synergistic effect helps to lower both fasting and post-meal blood sugar levels more effectively than either drug alone.
• In the case of SITAZIT DM 10/100/1000, the '10', '100', and '1000' likely refer to the dosages (in milligrams) of Sitagliptin and Metformin respectively along with its modified form. For example, '10/100/1000' could mean 10mg of Sitagliptin, 100mg of immediate-release Metformin, and 1000mg of extended-release Metformin. The extended-release (ER) formulation of Metformin provides a more gradual release of the drug into the bloodstream, which can help to reduce gastrointestinal side effects and provide more consistent blood sugar control throughout the day.
• By combining these medications into a single tablet, SITAZIT DM simplifies the treatment regimen for patients with type 2 diabetes, improving adherence and ultimately leading to better blood sugar control. It is important to take SITAZIT DM as prescribed by your doctor and to follow their recommendations for diet, exercise, and blood sugar monitoring.

Common side effects of SITAZIT DM 10/100/1000 Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are headache, dizziness, constipation, upper respiratory tract infection, sore throat, and skin reactions like rash or itching. Less common but potentially serious side effects include pancreatitis, severe allergic reactions (anaphylaxis), kidney problems, and liver problems. In rare cases, lactic acidosis (a buildup of lactic acid in the blood) can occur, especially in patients with kidney problems. Swelling of the face, lips, tongue, or throat (angioedema) is also a rare but serious side effect requiring immediate medical attention. Changes in blood counts, such as decreased white blood cells or platelets, have also been reported.

• If you miss a dose of SITAZIT DM 10/100/1000 TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep SITAZIT DM 10/100/1000MG TAB 1X10 away from the reach of children and pets.
• Store SITAZIT DM 10/100/1000MG TAB 1X10 at room temperature.

• Take SITAZIT DM 10/100/1000 Tablet as prescribed by your doctor. It's crucial to follow their instructions regarding dosage and timing to manage your blood sugar effectively. Consistency is key for optimal results.
• SITAZIT DM combines multiple medications into one tablet. Be aware of the potential side effects of each component (Sitagliptin, Metformin, and a third medication, dosage of which is 1000mg as per the drug name). Common side effects may include nausea, diarrhea, or stomach upset. If side effects persist or worsen, consult your doctor immediately.
• To minimize gastrointestinal discomfort, take SITAZIT DM with food. This helps your body better tolerate the medication and reduces the likelihood of nausea or diarrhea. Avoid taking it on an empty stomach.
• Regularly monitor your blood sugar levels as directed by your healthcare provider. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Keep a log of your readings to share with your doctor.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Drug interactions can occur and affect how SITAZIT DM works. This includes over-the-counter medications as well. A comprehensive list ensures your doctor can provide the safest and most effective treatment.
• Stay hydrated by drinking plenty of water throughout the day. This is especially important when taking Metformin, one of the components of SITAZIT DM, as it can sometimes cause dehydration. Water also aids in overall metabolic function.
• Adhere to a healthy diet and exercise regularly. SITAZIT DM is most effective when combined with lifestyle modifications. A balanced diet low in processed foods and regular physical activity can significantly improve blood sugar control.
• Be aware of the symptoms of hypoglycemia (low blood sugar), such as sweating, shakiness, dizziness, and confusion. If you experience these symptoms, consume a quick source of sugar, such as glucose tablets or fruit juice, and inform your doctor.
• Store SITAZIT DM in a cool, dry place away from direct sunlight and moisture. Proper storage ensures the medication remains effective. Keep it out of reach of children and pets.
• Attend all scheduled appointments with your doctor and other healthcare providers. Regular check-ups allow your doctor to monitor your progress, adjust your medication if needed, and address any concerns you may have. Don't hesitate to ask questions about your treatment plan.

• SITAZIT DM 10/100/1000 TABLET 10'S can be taken with or without food. However, it is recommended to take it at the same time each day to maintain consistent blood sugar levels. Consult your doctor for specific dietary advice while taking this medication.