DAPLO S 10/100MG TABLET 10'S
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DAPLO S 10/100MG TABLET 10'SDAPLO S 10/100MG TABLET 10'SDAPLO S 10/100MG TABLET 10'S
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DAPLO S 10/100MG TABLET 10'S

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DAPLO S 10/100MG TABLET 10'S

By DR REDDY'S LABORATORIES LIMITED

MRP

198

₹168.3

15 % OFF

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Product DetailsArrow

About DAPLO S 10/100MG TABLET 10'S

  • DAPLO S 10/100MG TABLET 10'S is a combination medicine designed to help manage blood sugar levels in adults with type 2 diabetes. It combines two powerful active ingredients: Dapagliflozin (10mg) and Sitagliptin (100mg). This dual-action approach provides comprehensive glycemic control, working through different mechanisms to lower blood sugar and improve overall metabolic health.
  • Dapagliflozin belongs to a class of medications known as SGLT2 inhibitors (sodium-glucose cotransporter 2 inhibitors). It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated through urine, effectively lowering blood sugar levels. This process also contributes to modest weight loss and blood pressure reduction in some individuals.
  • Sitagliptin, on the other hand, is a DPP-4 inhibitor (dipeptidyl peptidase-4 inhibitor). It works by increasing the levels of incretin hormones in the body. These hormones stimulate the release of insulin from the pancreas when blood sugar is high and reduce the amount of glucose produced by the liver. By enhancing the body's natural ability to regulate blood sugar, Sitagliptin helps to keep glucose levels within a healthy range.
  • DAPLO S 10/100MG TABLET is typically taken once daily, as prescribed by your doctor. It is important to follow your doctor's instructions carefully regarding dosage and timing. This medicine is most effective when used in conjunction with a healthy diet and regular exercise. Common side effects may include urinary tract infections, yeast infections, and changes in urination. Consult your doctor immediately if you experience any severe or persistent side effects.
  • This medication is a prescription drug, and it is essential to consult with a healthcare professional to determine if DAPLO S 10/100MG TABLET 10'S is right for you. They can assess your individual medical history, current medications, and overall health status to ensure that this medicine is safe and effective for your specific needs. Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

Uses of DAPLO S 10/100MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Reducing the risk of heart disease (in patients with type 2 diabetes)
  • Reducing the risk of kidney disease (in patients with type 2 diabetes)
  • Aiding in weight management in obese type 2 diabetes patients
  • Improving insulin sensitivity

How DAPLO S 10/100MG TABLET 10'S Works

  • DAPLO S 10/100MG Tablet is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It contains two active ingredients: Dapagliflozin and Sitagliptin, each working through different mechanisms to achieve better glycemic control.
  • Dapagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin inhibits this protein, preventing the kidneys from reabsorbing glucose. As a result, excess glucose is eliminated from the body through urine, leading to a reduction in blood sugar levels. This process is also associated with a mild diuretic effect, which can help lower blood pressure and potentially contribute to weight loss.
  • Sitagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood sugar levels are high and suppress glucagon secretion (a hormone that raises blood sugar) when blood sugar levels are low.
  • By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This results in enhanced insulin secretion, reduced glucagon secretion, and ultimately, better blood sugar control, particularly after meals. The glucose-dependent action of incretins minimizes the risk of hypoglycemia (low blood sugar).
  • The combination of Dapagliflozin and Sitagliptin provides a dual approach to managing type 2 diabetes. Dapagliflozin reduces glucose reabsorption in the kidneys, while Sitagliptin enhances the body's own ability to regulate blood sugar through incretin hormones. This synergistic effect can lead to significant improvements in HbA1c levels (a measure of average blood sugar over 2-3 months) and overall glycemic control.
  • It's important to note that DAPLO S 10/100MG Tablet is most effective when used in conjunction with lifestyle modifications, such as a healthy diet and regular exercise. It is also crucial to take the medication as prescribed by your doctor and to monitor blood sugar levels regularly to ensure optimal management of diabetes.

Side Effects of DAPLO S 10/100MG TABLET 10'SArrow

DAPLO S 10/100MG TABLET 10'S can cause several side effects, although not everyone experiences them. Common side effects may include: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Hypoglycemia (low blood sugar), Genital infections (both male and female), Urinary tract infections (UTIs), Increased urination, Thirst, Dizziness, Headache, Fatigue. Less common but potentially serious side effects include: Ketoacidosis (increased ketones in blood or urine), Kidney problems, Allergic reactions (rash, itching, swelling), Fournier's gangrene (a rare but serious infection of the genitals), Dehydration, Hypotension (low blood pressure), Increased cholesterol levels. It is important to contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for DAPLO S 10/100MG TABLET 10'SArrow

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Allergies

Allergies

Do not use Daplo S 10/100mg Tablet 10's if you are allergic to it.

Dosage of DAPLO S 10/100MG TABLET 10'SArrow

  • The recommended dosage of 'DAPLO S 10/100MG TABLET 10'S' varies depending on individual patient needs, kidney function, and other medications you may be taking. It is crucial to adhere strictly to your doctor's instructions regarding the dosage and timing of this medication. Typically, 'DAPLO S 10/100MG TABLET 10'S' is administered once daily, preferably in the morning, with or without food. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • Your physician will determine the most appropriate dosage based on your specific condition and response to treatment. Dosage adjustments may be necessary during the course of treatment. Do not alter the dosage yourself without consulting your healthcare provider. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It's important to note that 'DAPLO S 10/100MG TABLET 10'S' should be used as part of a comprehensive treatment plan for diabetes, which includes diet and exercise. Regular monitoring of your blood sugar levels and kidney function is also essential while taking this medication. If you experience any side effects or have any concerns about your dosage, contact your doctor immediately. Take 'DAPLO S 10/100MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of DAPLO S 10/100MG TABLET 10'S?Arrow

  • If you miss a dose of DAPLO S 10/100MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store DAPLO S 10/100MG TABLET 10'S?Arrow

  • Keep DAPLO S 10/100MG TAB 1X10 away from the reach of children and pets.
  • Store DAPLO S 10/100MG TAB 1X10 at room temperature.

Benefits of DAPLO S 10/100MG TABLET 10'SArrow

  • DAPLO S 10/100MG TABLET 10'S offers a dual-action approach to managing type 2 diabetes by combining the strengths of Dapagliflozin and Sitagliptin. This combination therapy works synergistically to improve glycemic control and provide several additional health benefits.
  • Dapagliflozin, an SGLT2 inhibitor, promotes the excretion of excess glucose through urine, effectively lowering blood sugar levels. This mechanism helps in reducing HbA1c levels, a key indicator of long-term blood sugar control. By reducing blood sugar, DAPLO S helps prevent the microvascular complications of diabetes, such as nephropathy (kidney damage), neuropathy (nerve damage), and retinopathy (eye damage).
  • Sitagliptin, a DPP-4 inhibitor, enhances the body's own ability to lower blood sugar by increasing the levels of incretin hormones. These hormones stimulate insulin release and reduce glucagon secretion in a glucose-dependent manner. The combined action of Dapagliflozin and Sitagliptin provides more effective blood sugar control compared to either medication alone.
  • Beyond glycemic control, DAPLO S 10/100MG TABLET 10'S can offer cardiovascular benefits, particularly through Dapagliflozin. Studies have shown that SGLT2 inhibitors can reduce the risk of cardiovascular events such as heart failure and stroke in patients with type 2 diabetes who also have established cardiovascular disease or multiple cardiovascular risk factors. Dapagliflozin also promotes modest weight loss by eliminating calories through urine, which can be beneficial for overweight or obese individuals with type 2 diabetes. This weight management is an added advantage in controlling blood sugar levels and improving overall metabolic health.
  • DAPLO S may help in reducing blood pressure. Dapagliflozin can lead to a slight reduction in systolic blood pressure, contributing to overall cardiovascular health. It is generally well-tolerated, with a lower risk of hypoglycemia (low blood sugar) compared to some other diabetes medications, especially when not used in combination with insulin or sulfonylureas. The convenience of a single tablet containing two medications improves patient compliance and simplifies the treatment regimen. Better adherence to the prescribed medication schedule leads to improved blood sugar control and reduced risk of complications.
  • The use of DAPLO S contributes to improved overall quality of life by effectively managing diabetes, reducing the risk of associated complications, and promoting better metabolic health. Always use under medical supervision.
  • DAPLO S helps to lower the risk of developing serious health issues related to diabetes, enhancing long-term health outcomes.

How to use DAPLO S 10/100MG TABLET 10'SArrow

  • DAPLO S 10/100MG TABLET 10'S should be taken orally, ideally in the morning, with or without food. However, to maintain consistency, it's best to take it at the same time each day. Swallow the tablet whole with a glass of water; do not crush, chew, or break it, as this can affect how the medication is released and absorbed in your body.
  • Before you start taking DAPLO S 10/100MG TABLET 10'S, carefully read the patient information leaflet provided by your pharmacist or doctor. This leaflet contains important information about the medication, including potential side effects and interactions with other drugs. If you have any questions or concerns, don't hesitate to ask your healthcare provider for clarification.
  • The dosage of DAPLO S 10/100MG TABLET 10'S will be determined by your doctor based on your individual needs and response to treatment. It's crucial to follow your doctor's instructions precisely and not to adjust the dosage on your own. Do not stop taking the medication without consulting your doctor, even if you feel better, as abruptly stopping it can lead to a worsening of your condition.
  • While taking DAPLO S 10/100MG TABLET 10'S, it's essential to monitor your blood sugar levels regularly, especially if you are also taking other diabetes medications. Keep a record of your blood sugar readings and share them with your doctor during your check-ups. This will help your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • In addition to taking DAPLO S 10/100MG TABLET 10'S, it's important to adopt a healthy lifestyle to manage your diabetes effectively. This includes following a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. Your doctor or a registered dietitian can provide you with personalized guidance on diet and exercise.
  • Be aware of potential side effects while taking DAPLO S 10/100MG TABLET 10'S. Common side effects may include urinary tract infections, yeast infections, and increased urination. If you experience any persistent or bothersome side effects, contact your doctor promptly. Serious side effects are rare but require immediate medical attention.
  • Store DAPLO S 10/100MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children. If you have any unused medication, dispose of it properly according to the instructions provided by your pharmacist or doctor. Never share your medication with others, even if they have similar symptoms.

Quick Tips for DAPLO S 10/100MG TABLET 10'SArrow

  • Take DAPLO S 10/100MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them, as this could affect your blood sugar levels and overall health. Typically, it's taken once daily, preferably in the morning.
  • DAPLO S 10/100MG TABLET 10'S works best when combined with a healthy lifestyle. This includes a balanced diet, regular exercise, and maintaining a healthy weight. Focus on whole grains, lean proteins, and plenty of fruits and vegetables, while limiting sugary drinks and processed foods. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • Stay well-hydrated while taking DAPLO S 10/100MG TABLET 10'S. Drink plenty of water throughout the day, unless your doctor has advised you otherwise due to other health conditions. Proper hydration supports kidney function and helps manage blood sugar levels effectively.
  • Monitor your blood sugar levels regularly as directed by your doctor. This helps you understand how DAPLO S 10/100MG TABLET 10'S and your lifestyle choices are affecting your glucose levels. Keep a record of your readings and share them with your healthcare provider during your appointments.
  • Be aware of the potential side effects of DAPLO S 10/100MG TABLET 10'S, such as urinary tract infections, yeast infections, and increased urination. If you experience any unusual or bothersome symptoms, contact your doctor promptly. Do not ignore any signs of discomfort, and seek medical advice for appropriate management.

Food Interactions with DAPLO S 10/100MG TABLET 10'SArrow

  • DAPLO S 10/100MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood sugar levels. Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of hypoglycemia (low blood sugar).

FAQs

What is DAPLO S 10/100MG Tablet 10'S and what is it used for?Arrow

DAPLO S 10/100MG Tablet 10'S is a combination of two medicines: Dapagliflozin and Sitagliptin. It is used to control high blood sugar levels in adults with type 2 diabetes.

How does DAPLO S 10/100MG Tablet 10'S work?Arrow

Dapagliflozin prevents glucose from being reabsorbed into your blood by your kidneys, causing more glucose to be excreted through your urine. Sitagliptin works by increasing insulin secretion and decreasing the amount of sugar your body makes.

What are the common side effects of DAPLO S 10/100MG Tablet 10'S?Arrow

The common side effects of DAPLO S 10/100MG Tablet 10'S include nausea, vomiting, diarrhea, stomach pain, headache, and respiratory infection.

Can DAPLO S 10/100MG Tablet 10'S cause kidney problems?Arrow

In rare cases, DAPLO S 10/100MG Tablet 10'S can cause kidney problems. It is important to tell your doctor if you have a history of kidney disease.

Can DAPLO S 10/100MG Tablet 10'S be taken with or without food?Arrow

DAPLO S 10/100MG Tablet 10'S can be taken with or without food, but it is best to take it at the same time each day.

What happens if I miss a dose of DAPLO S 10/100MG Tablet 10'S?Arrow

If you miss a dose of DAPLO S 10/100MG Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Is it safe to drink alcohol while taking DAPLO S 10/100MG Tablet 10'S?Arrow

It is not recommended to drink alcohol while taking DAPLO S 10/100MG Tablet 10'S, as it can increase the risk of low blood sugar.

Is DAPLO S 10/100MG Tablet 10'S safe during pregnancy?Arrow

The safety of DAPLO S 10/100MG Tablet 10'S during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.

Is DAPLO S 10/100MG Tablet 10'S safe during breastfeeding?Arrow

It is not known whether DAPLO S 10/100MG Tablet 10'S passes into breast milk. Consult your doctor before breastfeeding.

Can DAPLO S 10/100MG Tablet 10'S interact with other medications?Arrow

DAPLO S 10/100MG Tablet 10'S can interact with certain other medications, such as insulin and sulfonylureas. It is important to tell your doctor about all the medications you are taking.

How should I store DAPLO S 10/100MG Tablet 10'S?Arrow

Store DAPLO S 10/100MG Tablet 10'S at room temperature, away from heat and moisture.

Can DAPLO S 10/100MG Tablet 10'S cause weight loss?Arrow

DAPLO S 10/100MG Tablet 10'S may cause slight weight loss in some people, but it is not intended for weight loss.

Does DAPLO S 10/100MG Tablet 10'S reduce the risk of heart disease?Arrow

Some studies have shown that DAPLO S 10/100MG Tablet 10'S may reduce the risk of heart disease, but more research is needed to confirm this.

What happens if I overdose on DAPLO S 10/100MG Tablet 10'S?Arrow

If you think you have overdosed on DAPLO S 10/100MG Tablet 10'S, seek medical attention immediately. Symptoms of an overdose may include nausea, vomiting, diarrhea, and abdominal pain.

Can I take other diabetes medications with DAPLO S 10/100MG Tablet 10'S?Arrow

Consult your doctor before taking other diabetes medications with DAPLO S 10/100MG Tablet 10'S. Taking certain medications together can cause your blood sugar levels to drop too low.

References

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FDA - FARXIGA (dapagliflozin) tablets, for oral use. This is the prescribing information for dapagliflozin. It includes details on clinical studies, adverse reactions, and dosage.

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European Medicines Agency - Forxiga. This provides detailed information on Forxiga (dapagliflozin), including its uses, benefits and risks, and why it was authorized in the EU.

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DrugBank - Dapagliflozin. A comprehensive resource providing chemical structure, mechanism of action, uses, and pharmacological properties of dapagliflozin.

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FDA - Dapagliflozin pharmacology review. Pharmacology review of dapagliflozin.

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PMC - Dapagliflozin: a review of its use in the treatment of type 2 diabetes mellitus. A review article discussing the clinical efficacy and safety of dapagliflozin in treating type 2 diabetes.

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अस्वीकरण

यहां दिया गया कंटेंट सूचना के उद्देश्यों के लिए है और इसका उद्देश्य पेशेवर चिकित्सा सलाह, निदान या उपचार का विकल्प नहीं है। चिकित्सा स्थिति के संबंध में अपने किसी भी प्रश्न के लिए कृपया किसी चिकित्सक या अन्य योग्य स्वास्थ्य प्रदाता की सलाह लें। किसी भी जानकारी पर मेडकार्ट और उसके बाद की कार्रवाई या निष्क्रियता पूरी तरह से उपयोगकर्ता के जोखिम पर है, और हम इसके लिए कोई जिम्मेदारी नहीं लेते हैं। प्लेटफ़ॉर्म पर कंटेंट को पेशेवर और योग्य चिकित्सा सलाह के विकल्प के रूप में नहीं माना जाना चाहिए या उसका उपयोग नहीं किया जाना चाहिए। दवाओं, परीक्षणों और/या बीमारियों से संबंधित किसी भी प्रश्न के लिए कृपया अपने चिकित्सक से परामर्श करें, जैसा कि हम समर्थन करते हैं, और डॉक्टर-रोगी संबंध को प्रतिस्थापित न करें।

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