ROSUBEST F TABLET 10'S

How ROSUBEST F TABLET 10'S Works

• ROSUBEST F Tablet is a combination medicine containing Rosuvastatin and Fenofibrate. It's primarily used to manage abnormal lipid levels in the blood, specifically targeting high cholesterol and triglycerides. Understanding how each component works is crucial to appreciating the overall efficacy of ROSUBEST F.
• Rosuvastatin belongs to a class of drugs called statins. Statins primarily work by inhibiting an enzyme called HMG-CoA reductase. This enzyme is crucial in the liver's production of cholesterol. By blocking this enzyme, rosuvastatin reduces the amount of cholesterol the liver produces. This leads to a decrease in LDL cholesterol (the 'bad' cholesterol) in the bloodstream. Additionally, rosuvastatin can modestly increase HDL cholesterol (the 'good' cholesterol) and lower triglycerides. Rosuvastatin also helps the liver remove cholesterol already present in the blood, further contributing to its cholesterol-lowering effects.
• Fenofibrate, on the other hand, belongs to a class of drugs called fibrates. Fenofibrates primarily work by activating a protein called PPARα (peroxisome proliferator-activated receptor alpha). PPARα is found in the liver and other tissues and plays a key role in lipid metabolism. When activated by fenofibrate, PPARα increases the breakdown of triglycerides and promotes the removal of triglyceride-rich lipoproteins from the blood. This leads to a significant reduction in triglyceride levels. Additionally, fenofibrate can also increase HDL cholesterol levels and may have a modest effect on reducing LDL cholesterol.
• In essence, ROSUBEST F combines the cholesterol-lowering action of rosuvastatin with the triglyceride-lowering action of fenofibrate. This dual mechanism of action makes it particularly effective in individuals who have both high cholesterol and high triglycerides. By reducing LDL cholesterol, ROSUBEST F helps to prevent the buildup of plaque in the arteries, reducing the risk of heart attack and stroke. By lowering triglycerides, it reduces the risk of pancreatitis and other complications associated with high triglyceride levels. The combined effect provides a more comprehensive approach to managing dyslipidemia compared to using either drug alone. The synergistic action of these two drugs helps in achieving optimal lipid control and reduces the risk of cardiovascular events more effectively.

Like all medicines, ROSUBEST F TABLET 10'S can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Headache * Muscle pain * Feeling weak * Nausea * Dizziness * Increased blood sugar levels * Diabetes (this is more likely if you have high levels of sugar and fats in your blood, are overweight and have high blood pressure). **Uncommon side effects (may affect up to 1 in 100 people):** * Skin rash, itching, hives * Increased protein in the urine **Rare side effects (may affect up to 1 in 1,000 people):** * Severe allergic reaction – signs include swelling of the face, lips, tongue and/or throat, difficulty swallowing and breathing, and severe skin itching. * Muscle damage – precautions should be taken to recognize muscle damage and consult your doctor immediately. * Inflammation of the pancreas, which causes severe stomach pain. * Liver problems, including increased liver enzymes in the blood. **Very rare side effects (may affect up to 1 in 10,000 people):** * Jaundice (yellowing of the skin and whites of the eyes) * Hepatitis (inflammation of the liver) * Joint pain * Loss of memory * Breast enlargement in men (gynecomastia) **Side effects with unknown frequency (frequency cannot be estimated from the available data):** * Diarrhea * Cough * Shortness of breath (dyspnea) * Edema (swelling) * Sleep disturbances, including insomnia and nightmares * Sexual difficulties * Depression * Peripheral neuropathy (a nerve disorder that can cause pain, numbness, or tingling).

• If you miss a dose of ROSUBEST F TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep ROSUBEST F TAB 1X10 away from the reach of children and pets.
• Store ROSUBEST F TAB 1X10 at room temperature.

• Take ROSUBEST F TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your physician, as this could affect your cholesterol levels and overall health. Regular monitoring is essential to assess the effectiveness of the treatment.
• Maintain a heart-healthy lifestyle while taking ROSUBEST F TABLET 10'S. This includes following a balanced diet low in saturated and trans fats, engaging in regular physical activity (at least 30 minutes of moderate-intensity exercise most days of the week), and quitting smoking. These lifestyle changes can significantly enhance the benefits of the medication.
• Be aware of potential side effects. While ROSUBEST F TABLET 10'S is generally well-tolerated, some individuals may experience muscle pain or weakness (myalgia), which could rarely indicate a more serious condition called rhabdomyolysis. Report any unexplained muscle pain, tenderness, or weakness to your doctor immediately. Other possible side effects include digestive issues, headache, and liver abnormalities. Regular liver function tests may be recommended.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. ROSUBEST F TABLET 10'S can interact with certain drugs, potentially affecting their efficacy or increasing the risk of side effects. Pay particular attention to medications like cyclosporine, fibrates (other cholesterol-lowering drugs), and certain antibiotics or antifungals. A comprehensive review of your medication list will help your doctor ensure safe and effective treatment.
• Store ROSUBEST F TABLET 10'S properly. Keep the medication in its original container, tightly closed, and out of reach of children and pets. Store it at room temperature, away from direct sunlight and moisture. Do not use the medication if it has expired. Proper storage helps maintain the integrity and effectiveness of the drug.
• Attend all scheduled follow-up appointments with your doctor. Regular check-ups are crucial to monitor your cholesterol levels, assess your response to ROSUBEST F TABLET 10'S, and make any necessary adjustments to your treatment plan. These appointments also provide an opportunity to discuss any concerns or side effects you may be experiencing.

• ROSUBEST F TABLET 10'S generally does not have any significant interactions with food. It can be taken with or without food, as directed by your healthcare provider. However, it is advisable to maintain a consistent dietary pattern while taking this medication.