ABHAYRAB INJECTION 0.5 ML

How ABHAYRAB INJECTION 0.5 ML Works

• ABHAYRAB INJECTION 0.5 ML is a rabies vaccine that works by stimulating the body's immune system to produce antibodies against the rabies virus. These antibodies neutralize the virus, preventing it from infecting cells and causing disease. The vaccine contains inactivated rabies virus, which means the virus has been treated so that it cannot cause infection but can still trigger an immune response.
• Upon injection, the inactivated rabies virus is recognized as a foreign substance by the immune system. This recognition triggers a series of events involving various immune cells, including macrophages, dendritic cells, and lymphocytes (B cells and T cells). Macrophages and dendritic cells engulf and process the inactivated virus, presenting viral antigens (specific proteins of the virus) to T helper cells.
• T helper cells then activate B cells, which are responsible for producing antibodies. These antibodies are specifically designed to bind to the rabies virus. When the rabies virus enters the body after a potential exposure (e.g., through a bite from a rabid animal), these pre-existing antibodies bind to the virus, preventing it from attaching to and entering nerve cells. This neutralization process is crucial in preventing the virus from traveling to the brain and causing the severe neurological symptoms associated with rabies.
• In addition to antibody production, the vaccine also stimulates the development of memory B cells and T cells. These memory cells provide long-term immunity, meaning that if the individual is exposed to the rabies virus again in the future, the immune system will be able to mount a rapid and effective response, quickly producing antibodies and preventing the disease. The development of both antibodies and cellular immunity is essential for the overall protection provided by the ABHAYRAB INJECTION 0.5 ML.
• The typical immunization schedule involves multiple doses of the vaccine to ensure a strong and lasting immune response. Post-exposure prophylaxis (PEP), which includes the rabies vaccine and rabies immunoglobulin (RIG), is crucial in preventing the development of rabies after a potential exposure. RIG provides immediate, passive immunity by directly injecting antibodies into the wound site, while the vaccine stimulates the body to actively produce its own antibodies for long-term protection. The combination of RIG and the vaccine offers the best chance of preventing rabies in individuals exposed to the virus. The vaccine's effectiveness relies on the body's ability to mount an immune response, which can be influenced by factors such as the individual's health status and immune system function.

Like all medicines, Abhayrab injection can cause side effects, although not everybody gets them. **Common Side Effects:** * Pain, redness, swelling, or itching at the injection site * Headache * Muscle aches (myalgia) * Joint pain (arthralgia) * Fatigue * Fever * Nausea * Dizziness **Uncommon Side Effects:** * Hives (urticaria) * Swelling of the face or throat (angioedema) * Difficulty breathing * Vomiting * Abdominal pain * Swollen glands (lymphadenopathy) **Rare Side Effects:** * Guillain-Barré syndrome (a rare autoimmune disorder that affects the nerves) * Encephalitis (inflammation of the brain) * Nerve disorders (such as neuritis) **If you experience any of the following serious side effects, seek immediate medical attention:** * Severe allergic reaction (anaphylaxis) with symptoms such as difficulty breathing, swelling of the face or throat, and a sudden drop in blood pressure * Neurological symptoms such as numbness, tingling, muscle weakness, vision changes, or seizures

• If you miss a dose of Abhayrab Injection 0.5 ml, please consult your doctor immediately to determine the appropriate course of action. Do not delay, as timely administration is crucial for effective rabies prevention. Your doctor will advise you on when to receive the next dose and how to proceed with the vaccination schedule.

• Keep ABHAYRAB VACCINE 0.5ML away from the reach of children and pets.
• Store ABHAYRAB VACCINE 0.5ML in a refrigerator (2 - 8°C). Do not freeze.

• **Complete the Full Vaccination Course:** Abhayrab injection is most effective when administered as a complete post-exposure prophylaxis (PEP) or pre-exposure prophylaxis (PrEP) course as determined by your healthcare provider. Do not skip any scheduled doses, even if you feel well or the animal bite seems minor. Adhering to the prescribed schedule is crucial for developing adequate immunity against rabies.
• **Seek Immediate Medical Attention After a Potential Exposure:** If you are bitten, scratched, or have come into contact with the saliva of a potentially rabid animal, wash the wound thoroughly with soap and water for at least 15 minutes and seek immediate medical attention. Abhayrab is most effective when administered promptly after exposure. Delaying treatment can significantly reduce its effectiveness.
• **Understand the Difference Between PEP and PrEP:** Post-exposure prophylaxis (PEP) is given after a potential exposure to rabies, while pre-exposure prophylaxis (PrEP) is given to individuals at high risk of exposure, such as veterinarians, animal handlers, and travelers to rabies-prone areas. Discuss with your doctor which regimen is appropriate for you based on your risk factors. Note that even with PrEP, PEP might be needed if an exposure happens.
• **Report Animal Bites:** In many jurisdictions, animal bites are required to be reported to local health authorities. Reporting helps track potential rabies cases and allows for appropriate public health interventions. Ensure you are aware of and comply with local reporting requirements after any animal bite.
• **Be Aware of Potential Side Effects and When to Seek Help:** Like all medications, Abhayrab can cause side effects. Common side effects include pain, redness, or swelling at the injection site, headache, muscle aches, and fatigue. While most side effects are mild, seek immediate medical attention if you experience severe allergic reactions such as difficulty breathing, hives, or swelling of the face, lips, tongue, or throat. Contact your doctor if you have any concerns about side effects or if they worsen over time.
• **Inform Your Doctor of Other Medications and Medical Conditions:** Before receiving Abhayrab, inform your doctor about any other medications you are taking, including over-the-counter drugs and supplements, as well as any underlying medical conditions you have, such as immune system disorders. Certain medications or conditions may affect the effectiveness of Abhayrab or increase the risk of side effects. This information will help your doctor determine the best course of treatment for you.

• ABHAYRAB INJECTION 0.5 ML does not have any known interactions with food. It can be administered without regard to food intake.