ADRIPEG 20 INJECTION
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ADRIPEG 20 INJECTION
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ADRIPEG 20 INJECTION

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ADRIPEG 20 INJECTION

By HALSTED PHARMA PVT LTD

MRP

₹

4800

₹2601

45.81 % OFF

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Product DetailsArrow

About ADRIPEG 20 INJECTION

  • ADRIPEG 20 INJECTION is an anticancer medication belonging to the anthracycline topoisomerase inhibitor class. Its active ingredient, doxorubicin, is encapsulated within a liposome (a closed lipid sphere), which is further coated with polyethylene glycol (PEG). This PEG coating enhances the drug's circulation time in the bloodstream, facilitating its targeted delivery to cancerous cells while minimizing exposure to healthy tissues. It is used as a single therapy for metastatic breast cancer patients with increased cardiac risk associated with conventional doxorubicin. It is also prescribed for ovarian cancer and AIDS-related Kaposi’s sarcoma. Additionally, it is used in combination therapy for multiple myeloma (cancer of plasma cells, a type of white blood cell).
  • ADRIPEG 20 INJECTION's targeted delivery mechanism helps to reduce the side effects often associated with traditional chemotherapy, making it a valuable option for patients who may be more vulnerable to these effects. The liposomal encapsulation protects the doxorubicin, preventing it from being immediately released into the body and allowing it to accumulate in tumor tissues, where blood vessels tend to be leakier. This targeted accumulation maximizes the drug's effectiveness against cancer cells while sparing healthy cells.
  • This medication is generally not recommended for individuals with allergies to pegylated liposomal doxorubicin or any of its components. It is also contraindicated in those with allergies to products containing pea or soy. The safety and efficacy of ADRIPEG 20 INJECTION have not been established in children and adolescents under 18 years of age. Geriatric patients may use it, but dosage adjustments may be necessary based on age and body weight. Use of this medicine is not recommended if you are pregnant or breastfeeding. It is crucial to use effective birth control methods during treatment and for at least six months after the final dose. ADRIPEG 20 INJECTION can potentially cause heart problems, and therefore, caution is advised in patients with a history of cardiovascular disease. Regular monitoring of cardiac function is essential during therapy.
  • Before starting treatment with ADRIPEG 20 INJECTION, inform your doctor about any existing heart or liver conditions, diabetes, Kaposi’s sarcoma, or oral health problems. Disclose all medications you are currently taking, including prescription drugs, over-the-counter medications, herbal remedies, and dietary supplements. Regular monitoring by your healthcare provider is important to assess the drug's effectiveness and manage any potential side effects.

Uses of ADRIPEG 20 INJECTION

  • Metastatic Breast Cancer: ADRIPEG 20 INJECTION is often used in the treatment of metastatic breast cancer, where the cancer has spread from the breast to other parts of the body. It helps to slow down the growth and spread of cancer cells, improving the patient's overall quality of life and potentially extending their lifespan.
  • Ovarian Cancer: ADRIPEG 20 INJECTION is a valuable treatment option for ovarian cancer, particularly in cases where other chemotherapy drugs have not been effective. It targets and destroys cancer cells within the ovaries, helping to manage the disease and improve patient outcomes.
  • Multiple Myeloma: ADRIPEG 20 INJECTION is used in the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. It helps to control the growth of these abnormal cells, alleviating symptoms and improving the patient's prognosis.
  • AIDS-related Kaposi’s Sarcoma: ADRIPEG 20 INJECTION plays a significant role in treating Kaposi's sarcoma, a cancer that develops in people with AIDS (Acquired Immunodeficiency Syndrome). It helps to reduce the size and spread of Kaposi's sarcoma lesions, improving the patient's comfort and overall health.

Side Effects of ADRIPEG 20 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. ADRIPEG 20 INJECTION can cause both serious and common side effects.

  • Severe diarrhea, sores in mouth, nausea, vomiting
  • Hand foot syndrome
  • Lung infections, shortness of breath
  • Severe stomach pain
  • Seizures
  • Severe weakness
  • Tachycardia
  • Low blood cell counts
  • Hair loss
  • Decreased appetite
  • Skin rashes
  • Pain in the muscles and joints
  • Constipation
  • Conjunctivitis
  • Feeling confused, difficulty sleeping
  • Headache, dizziness, sleepiness
  • Change in taste
  • High or low blood pressure
  • Excessive sweating
  • Pain when passing urine
  • Weight loss
  • Muscle spasms

Safety Advice for ADRIPEG 20 INJECTIONArrow

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Pregnancy

UNSAFE

ADRIPEG 20 INJECTION may harm the unborn baby and may cause foetal abnormalities. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medicine.

Dosage of ADRIPEG 20 INJECTIONArrow

  • ADRIPEG 20 INJECTION will be administered to you by a healthcare professional via intravenous infusion, meaning it's delivered directly into a vein. This process, often referred to as a drip, can take anywhere from 30 minutes to over an hour. The exact duration depends on several factors, including the prescribed dosage and the specific condition being treated. Your doctor will carefully determine the appropriate dosage and frequency of ADRIPEG 20 INJECTION based on a thorough assessment of your individual needs.
  • Factors considered by your physician when determining the correct dosage and administration schedule include the severity of your condition, your overall health, and any other medications you may be taking. It's crucial to follow your doctor's instructions precisely regarding the frequency and duration of treatment. This medication is always administered under the supervision of trained medical personnel. Self-administration is strictly prohibited to ensure your safety and the effectiveness of the treatment. You will be closely monitored during the infusion for any potential side effects or complications.
  • The healthcare professional administering ADRIPEG 20 INJECTION will have the expertise to manage any adverse reactions that may occur during the infusion. They will also be able to answer any questions or address any concerns you may have about the treatment. Remember to inform your doctor about all your medical conditions and medications to ensure the safe and effective use of ADRIPEG 20 INJECTION.

How to store ADRIPEG 20 INJECTION?Arrow

  • Keep ADRIPEG 20MG INJ 10ML away from the reach of children and pets.
  • Store ADRIPEG 20MG INJ 10ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ADRIPEG 20 INJECTIONArrow

  • ADRIPEG 20 INJECTION utilizes liposomes coated with polyethylene glycol (PEG) to precisely target tumors, ensuring selective drug release directly into cancer cells. This targeted approach minimizes exposure to healthy tissues, reducing potential side effects. Once inside the cancer cells, doxorubicin, the active ingredient, disrupts the very core of cancer cell function.
  • Doxorubicin works by integrating itself into the DNA strands of cancer cells, effectively blocking transcription and DNA replication – processes vital for cell growth and division. Furthermore, it interferes with topoisomerase II enzymes, which play a critical role in DNA repair. By disrupting these functions, ADRIPEG 20 INJECTION triggers apoptosis (programmed cell death), cell cycle arrest (stopping cell division), and significant DNA damage in cancer cells.
  • In addition to these direct effects on DNA, doxorubicin also generates reactive oxygen species (ROS). These ROS amplify oxidative stress within the cancer cells, overwhelming their defenses and accelerating their demise. This multi-pronged attack makes ADRIPEG 20 INJECTION a powerful tool in cancer treatment.
  • The liposomal formulation of ADRIPEG 20 INJECTION is specifically designed to extend the drug's circulation time in the bloodstream. This prolonged circulation allows more of the drug to reach the tumor site. The liposomes also facilitate the preferential delivery of doxorubicin to cancerous tissues over healthy tissues, maximizing its effectiveness while minimizing harm to the body.

How to use ADRIPEG 20 INJECTIONArrow

  • ADRIPEG 20 INJECTION will be administered to you by a healthcare professional via an intravenous infusion (drip) directly into a vein. The duration of the infusion can vary, typically ranging from 30 minutes to over an hour, depending on several factors including the specific dosage prescribed and your individual medical condition. The precise dosage and the frequency with which you receive ADRIPEG 20 INJECTION will be carefully determined by your physician, taking into account the nature and severity of your disease, as well as other relevant health considerations. It is crucial to understand that ADRIPEG 20 INJECTION must be administered by a trained healthcare provider. Self-administration is strictly prohibited.
  • During the infusion, you will be closely monitored for any potential side effects or adverse reactions. Your healthcare team will be equipped to manage any complications that may arise. It is important to inform your doctor about any existing medical conditions you have, as well as any medications you are currently taking, including over-the-counter drugs and herbal supplements. This information will help your doctor determine the most appropriate dosage and administration schedule for you. The aim of ADRIPEG 20 INJECTION treatment is to effectively manage your condition while minimizing any potential risks.

FAQs

Doxorubicin or pegylated liposomal doxorubicin: which is superior?Arrow

Doxorubicin functions by inhibiting topoisomerase 2, an enzyme required by cancer cells for growth and division. Liposomal doxorubicin is doxorubicin that has been encapsulated in small particles known as pegylated liposomes that makes more doxorubicin reach the cancer cells because these spheres prolong the drug's half-life in the circulation.

What is the use of ADRIPEG 20 INJECTION?Arrow

This medication is used to treat breast cancer, ovarian cancer, multiple myeloma (cancer of white blood cells called plasma cells) and AIDS-related Kaposi’s sarcoma.

Is it safe to use ADRIPEG 20 INJECTION while driving?Arrow

No, it is unsafe to use this medication while driving and handling heavy machinery as it causes lack of concentration and alertness.

What are the side effects of ADRIPEG 20 INJECTION?Arrow

The common side effects of these medications are nausea, vomiting, rash, weakness, low blood platelets, fatigue, fever, loss of appetite, anaemia, and constipation.

Is it safe to use ADRIPEG 20 INJECTION during pregnancy?Arrow

It is unsafe to use this medication in patients planning for pregnancy or during pregnancy and breastfeeding mothers as it causes harmful effects for the baby.

What should I have to monitor while taking ADRIPEG 20 INJECTION?Arrow

Your healthcare professional may monitor you for infusion reactions while administering the drug. Regular monitoring of blood counts and cardiac function is necessary.

NULL interaction of ADRIPEG 20 INJECTION with other drungsArrow

NULL

What is an advice related to ADRIPEG 20 INJECTION?Arrow

It is not recommended to use this drug if you are allergic to the active compound pegylated liposomal doxorubicin and its components. It is also not recommended for use if you are allergic to products like pea and soy. Blood glucose levels, blood pressure, and liver and kidney function should be monitored regularly while taking this medication. Don't stop this medication without the proper advice of the doctor. It is recommended to monitor your liver, heart and lung functions during the treatment course. Avoid making plans for pregnancy or during pregnancy, as this medication can cause harmful effects on the developing baby. It is recommended to use effective contraceptive measures during the treatment and up to 8 months after the treatment has been withdrawn. Avoid driving after taking this medication because it causes dizziness and lack of concentration. The drug may cause decreased bone marrow activity. Monitoring complete blood counts regularly during therapy and watching for infections is advisable.To manage the treatment related to diarrhoea it is recommended to drink at least 3 litres of water and it is advised to wear masks and stay indoors as this medication lowers the blood cell count that may decrease the immunity.

What molecule/combination is used for making ADRIPEG 20 INJECTION?Arrow

PEGYLATED LIPOSOMAL DOXORUBICIN is molecule/combination used for making ADRIPEG 20 INJECTION.

For which ailments/diseases/conditions ADRIPEG 20 INJECTION is prescribed?Arrow

ADRIPEG 20 INJECTION is prescribed for Oncology.

References

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Baxter

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Baxter Healthcare Limited, Electronic medicines compendium (EMC)

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Baxter Healthcare Corporations, US Food and Drug Administration

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Ratings & Review

Good series, satisfied customer

Sameer Jadhav

•

Reviewed on 06-01-2024

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(5/5)

Excellent 👍👍👍

ashok badhala

•

Reviewed on 26-11-2022

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(5/5)

Very good place for medicine allmost all the medicine are available at discounted rate.

Sachin Dodhiwala

•

Reviewed on 10-03-2024

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(5/5)

Very good service and discount

Yatin Patel

•

Reviewed on 13-01-2024

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(5/5)

Staf behaviour and madicine knowledge was good.

Ranjana Bhati

•

Reviewed on 13-01-2024

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(5/5)

Marketer / Manufacturer Details

HALSTED PHARMA PVT LTD

Country of Origin -

India

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ADRIPEG 20 INJECTION

ADRIPEG 20 INJECTION

MRP

₹

4800

₹2601

45.81 % OFF

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