PEGADRIA 20 INJECTION
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PEGADRIA 20 INJECTION
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PEGADRIA 20 INJECTION

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PEGADRIA 20 INJECTION

By INTAS PHARMACEUTICALS LIMITED

MRP

3169

₹2557

19.31 % OFF

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Product DetailsArrow

About PEGADRIA 20 INJECTION

  • PEGADRIA 20 INJECTION is an anticancer medication containing doxorubicin, an active ingredient carefully enclosed within a lipid sphere called a liposome. This targeted delivery system helps to maximize the drug's effectiveness while potentially reducing side effects. Cancer is characterized by the unchecked and abnormal proliferation of cells, leading to various health complications.
  • This medication is indicated for the treatment of several types of cancers, including breast cancer, ovarian cancer, multiple myeloma (a cancer affecting plasma cells, a type of white blood cell), and AIDS-related Kaposi’s sarcoma. Kaposi’s sarcoma, a cancer that develops in the lining of lymph and blood vessels, poses a significant risk to individuals with HIV infection. PEGADRIA 20 INJECTION can be administered as a standalone treatment or in conjunction with other anticancer medications, depending on the specific type and stage of cancer.
  • It is generally not recommended for use in adolescents and children due to potential risks and the need for further research in these age groups. If you are undergoing treatment with PEGADRIA 20 INJECTION, it is crucial to use effective birth control methods during the treatment period and for at least six months after the final dose to prevent potential harm to a developing fetus.
  • Before starting PEGADRIA 20 INJECTION, inform your doctor about any allergies you may have, especially to peanuts or soya, as these components might be present in the medication's formulation. It is also essential to disclose if you are currently taking any medications for heart or liver disorders, or if you have a history of diabetes, Kaposi’s sarcoma, or any oral health issues. This information will help your doctor assess the potential risks and benefits of the treatment and make informed decisions regarding your care.

Uses of PEGADRIA 20 INJECTION

  • Breast cancer: This injection helps in the treatment of breast cancer.
  • Ovarian cancer: This injection is given to treat ovarian cancer.
  • Multiple myeloma: This injection assists in the treatment of multiple myeloma.
  • AIDS-related Kaposi’s sarcoma: This injection is used for treating AIDS-related Kaposi’s sarcoma.

Side Effects of PEGADRIA 20 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

  • Fever, tiredness, bruising or bleeding
  • Severe diarrhea, sores in mouth, nausea, vomiting
  • Lung infections, shortness of breath
  • Severe stomach pain
  • Severe weakness
  • Low blood cell counts
  • Hair loss
  • Decreased appetite
  • Skin rashes
  • Pain in the muscles and joints
  • Constipation
  • Feeling confused, difficulty sleeping
  • Headache, dizziness, sleepiness
  • Change in taste
  • High or low blood pressure
  • Excessive sweating
  • Pain when passing urine
  • Weight loss
  • Muscle spasms
  • Fast heartbeat

Safety Advice for PEGADRIA 20 INJECTIONArrow

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Pregnancy

UNSAFE

PEGADRIA 20 INJECTION may harm the unborn baby. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medicine.

Dosage of PEGADRIA 20 INJECTIONArrow

  • The appropriate dosage and how often you receive PEGADRIA 20 INJECTION will be determined by your doctor. This decision will be based on your specific medical condition, its severity, and other individual factors relevant to your health profile. This medication will be administered to you by a qualified healthcare professional in a clinical setting. It is crucial that you do not attempt to self-administer this injection.
  • Self-administration can lead to improper technique, incorrect dosage, and potential complications. Your healthcare provider is trained to administer PEGADRIA 20 INJECTION safely and effectively, ensuring you receive the maximum benefit from the treatment.
  • Adhering to the prescribed dosage and administration schedule is vital for optimal results. If you have any questions or concerns about your treatment plan, please discuss them with your physician or healthcare team. They can provide personalized guidance and address any anxieties you may have.

How to store PEGADRIA 20 INJECTION?Arrow

  • Keep PEGADRIA 20MG INJ 10ML away from the reach of children and pets.
  • Store PEGADRIA 20MG INJ 10ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of PEGADRIA 20 INJECTIONArrow

  • PEGADRIA 20 INJECTION utilizes a novel drug delivery system involving liposomes, which are microscopic vesicles designed to encapsulate and transport the active ingredient, doxorubicin HCl. This targeted approach enhances the drug's effectiveness and minimizes its impact on healthy cells.
  • The primary mechanism of action of doxorubicin HCl centers around its interaction with DNA, the genetic material within cells. By binding to DNA, doxorubicin HCl disrupts the process of nucleic acid synthesis, which is essential for cell replication and growth. This interference ultimately inhibits cell division and leads to cell death, particularly in rapidly dividing cancer cells.
  • Research indicates that doxorubicin HCl exhibits rapid cellular uptake, allowing it to quickly reach its target within the cell. Once inside, it binds to specific proteins associated with DNA, further disrupting DNA's function and stability. This multi-faceted approach ensures a potent anti-cancer effect.
  • The liposomal formulation of PEGADRIA 20 INJECTION contributes to improved drug distribution within the body, potentially leading to higher concentrations of the drug at the tumor site. This enhanced targeting can improve treatment outcomes and reduce systemic toxicity.
  • PEGADRIA 20 INJECTION offers a targeted therapy approach by inhibiting cell division and nucleic acid synthesis, crucial for cancerous cell growth.

How to use PEGADRIA 20 INJECTIONArrow

  • Your doctor will determine the appropriate dose and how often you receive PEGADRIA 20 INJECTION based on your specific medical condition and other individual factors. This medication will be administered to you by a qualified healthcare professional. It is crucial that you do not attempt to self-administer this injection.
  • The dosage schedule is carefully tailored to your needs to ensure the best possible outcome. Factors such as the severity of your condition, your overall health, and any other medications you are taking will all be considered when determining the right dose for you.
  • Administering this injection requires specialized training and knowledge, which is why it must be performed by a healthcare professional. They will know the correct technique and can monitor you for any potential side effects during and after the injection. Always follow your healthcare provider's instructions precisely for optimal results and to minimize the risk of complications.

FAQs

What is the use of PEGADRIA 20 INJECTION?Arrow

This medication is used to treat breast cancer, ovarian cancer, multiple myeloma (cancer of white blood cells called plasma cells) and AIDS-related Kaposi’s sarcoma.

Is it safe to use PEGADRIA 20 INJECTION while driving?Arrow

No, it is unsafe to use this medication while driving and handling heavy machinery as it causes lack of concentration and alertness.

How does PEGADRIA 20 INJECTION work?Arrow

It damages the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

What are the side effects of PEGADRIA 20 INJECTION?Arrow

The common side effects of these medications are nausea, vomiting, rash, weakness, low blood platelets, Fatigue, Fever, Loss of appetite, Anemia, and Constipation.

Is it safe to use PEGADRIA 20 INJECTION during pregnancy?Arrow

It is unsafe to use this medication in patients planning for pregnancy or during pregnancy and breastfeeding mothers as it causes harmful effects for the baby.

Does PEGADRIA 20 INJECTION interact with other drugs?Arrow

No known interactions of PEGADRIA 20 INJECTION with other drugs.

What precautions should I take while using PEGADRIA 20 INJECTION?Arrow

Avoid prolonged sun exposure and unnecessary heat exposure (such as hot dishwater and long hot baths). Avoid pressure on elbows, knees, and soles of feet (such as leaning on elbows, kneeling, and long walks). Wear loose clothing. Keep this medicine out of sight and reach of children. Store the tablets at room temperature. Avoid keeping the tablet in direct sunlight or excessive moisture. Pegylated liposomal doxorubicin may cause dizziness. If you are affected by this side effect, do not drive, use machinery, or do anything that needs alert until you can do it safely.

What molecule/combination is used for making PEGADRIA 20 INJECTION?Arrow

PEGYLATED LIPOSOMAL DOXORUBICIN is molecule/combination used for making PEGADRIA 20 INJECTION.

For what ailments/diseases/conditions is PEGADRIA 20 INJECTION prescribed?Arrow

PEGADRIA 20 INJECTION is prescribed for Oncology related ailments.

References

Book Icon

Baxter Holding BV, European medicines agency (ema), https://www.ema.europa.eu/en/documents/product-information/caelyx-pegylated-liposomal-epar-product-information_en.pdf

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Ben Venue Laboratories, Inc, US Food and Drug Administration, https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050718s029lbl.pdf

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Good representation and good communication to the cx very helpfull

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Best place for generic medicine at the cheapest rate

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Reviewed on 03-04-2022

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Good discounts available for all medicine.

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Reviewed on 01-12-2023

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(4/5)

Discount on medicine is good But OTC discount is zero and very low

Abhishek Solanki

Reviewed on 05-12-2022

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(3/5)


Marketer / Manufacturer Details

INTAS PHARMACEUTICALS LIMITED

Country of Origin -

India

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MRP

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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