AMFOEVA 50MG INJECTION
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AMFOEVA 50MG INJECTION
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AMFOEVA 50MG INJECTION

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AMFOEVA 50MG INJECTION

By CONCORD BIOTECH LTD

MRP

3696

₹2956.8

20 % OFF

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Product DetailsArrow

About AMFOEVA 50MG INJECTION

  • AMFOEVA 50MG INJECTION contains liposomal amphotericin B as its active ingredient, an antifungal antibiotic crucial in combating severe fungal infections. This medication is primarily administered to treat systemic fungal infections affecting one or more deep-seated organs within the body. It is also a key treatment option for individuals suspected of having fungal infections, particularly when they present with a high fever and neutropenia, a condition characterized by a significantly reduced count of white blood cells, which are essential for fighting off infections.
  • Furthermore, AMFOEVA 50MG INJECTION is indicated for the treatment of visceral leishmaniasis, a parasitic disease prevalent in certain regions and transmitted by sandflies. This condition affects the internal organs, particularly the spleen, liver, and bone marrow, causing a range of symptoms and potentially severe complications if left untreated.
  • Before your first treatment with AMFOEVA 50MG INJECTION, your healthcare provider may administer a small test dose to monitor for any potential allergic reactions. It is imperative to inform your physician if you have any known allergies to amphotericin B or any other components of the injection. You should also disclose any pre-existing medical conditions, such as severe allergic reactions, kidney or liver issues, or if you are currently undergoing dialysis. Additionally, it is crucial to inform your doctor if you have low potassium levels, as this medication can further affect potassium balance.
  • Each vial of AMFOEVA 50MG INJECTION contains sugar; therefore, individuals with diabetes must inform their physician to ensure proper management and monitoring of blood sugar levels during treatment. If you are pregnant, planning to become pregnant, or breastfeeding, it is essential to discuss the potential risks and benefits of using this medication with your doctor.
  • Common side effects associated with AMFOEVA 50MG INJECTION may include skin rash, low potassium levels, diarrhea, anemia, insomnia, and shortness of breath. This medication is generally not recommended for use in infants under one month of age due to potential risks. Always consult with your healthcare provider for detailed information and guidance regarding the use of AMFOEVA 50MG INJECTION.

Uses of AMFOEVA 50MG INJECTION

  • Fungal infections affecting one or multiple deep-seated organs within the body.
  • In cases of suspected fungal infections where diagnosis is underway.
  • Treatment for visceral leishmaniasis, also known as Kala-azar, a parasitic disease.

Side Effects of AMFOEVA 50MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. AMFOEVA 50MG INJECTION can cause side effects, ranging from common to serious.

  • Skin rash
  • Increased blood sugar levels
  • Decreased potassium levels
  • Diarrhea
  • Nausea, vomiting
  • Anemia
  • Insomnia
  • Shortness of breath
  • Fever, chills or shivering
  • Cardiac arrest
  • GI bleeding
  • Severe skin reactions
  • Acute kidney injury

Safety Advice for AMFOEVA 50MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant before receiving AMFOEVA 50MG INJECTION.

Dosage of AMFOEVA 50MG INJECTIONArrow

  • AMFOEVA 50MG INJECTION is administered by a healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. The medication is delivered intravenously through an infusion drip directly into your vein. It is crucial to understand that this injection should never be self-administered.
  • The dosage and duration of your treatment with AMFOEVA 50MG INJECTION will be determined by your doctor. They will carefully consider several factors, including the severity of your condition, your body weight, and other relevant health considerations to establish the most appropriate treatment plan for you. It is vital to adhere to the prescribed dosage and schedule to ensure the medication's effectiveness and minimize the risk of potential side effects.
  • Following your doctor's instructions closely is essential for achieving the best possible outcome from your treatment with AMFOEVA 50MG INJECTION. If you have any questions or concerns about the administration or dosage, do not hesitate to discuss them with your healthcare provider. They can provide clarification and address any anxieties you may have.

How to store AMFOEVA 50MG INJECTION?Arrow

  • Keep AMFOEVA 50MG INJ away from the reach of children and pets.
  • Store AMFOEVA 50MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of AMFOEVA 50MG INJECTIONArrow

  • AMFOEVA 50MG INJECTION is an antifungal medication that works by targeting a crucial component of fungal cell membranes called ergosterol. Ergosterol is essential for maintaining the integrity and proper function of these membranes. AMFOEVA 50MG INJECTION binds specifically to ergosterol, disrupting the fungal cell membrane's structure. This interaction leads to increased permeability, essentially creating pores or channels in the membrane. As a result, vital intracellular contents, such as ions, proteins, and other essential molecules, leak out of the fungal cell. This leakage disrupts the cell's normal function and ultimately leads to cell death. By targeting ergosterol, AMFOEVA 50MG INJECTION effectively eliminates the fungal infection, helping to restore the body's natural balance.
  • The drug's mechanism of action makes it effective against a broad spectrum of fungal infections. The disruption of the cell membrane is a critical point of attack, and because it directly compromises the physical integrity of the fungus, resistance is less likely to develop compared to drugs that target metabolic processes. This direct action on the membrane ensures that the fungal cell cannot maintain its internal environment, leading to its demise. This makes AMFOEVA 50MG INJECTION a powerful tool in combating various fungal infections, particularly in cases where other treatments may not be effective or tolerated.
  • Furthermore, the binding affinity of AMFOEVA 50MG INJECTION to ergosterol ensures that it selectively targets fungal cells, minimizing harm to human cells, which do not contain ergosterol. This selectivity is crucial for reducing potential side effects and improving the overall safety profile of the medication.

How to use AMFOEVA 50MG INJECTIONArrow

  • AMFOEVA 50MG INJECTION is administered by a healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. The medication is delivered intravenously, meaning it's given through a drip directly into your vein. It is crucial not to attempt self-administration of this injection. The dosage and the length of the treatment are carefully determined by your doctor.
  • Several factors influence the doctor's decision regarding the appropriate dosage and duration of treatment. These include the severity of your condition, your body weight, and other relevant medical considerations. Your doctor will continuously monitor your response to AMFOEVA 50MG INJECTION and may adjust the dosage accordingly to achieve the best possible outcome.
  • The healthcare professional will closely monitor you during and after the AMFOEVA 50MG INJECTION infusion to watch for any potential side effects or complications. It is important to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking before starting the treatment. This information will help your doctor make informed decisions about your care and minimize the risk of adverse reactions.

FAQs

What is AMFOEVA 50MG INJECTION?Arrow

AMFOEVA 50MG INJECTION is a medication used to treat severe fungal infections, such as invasive or systemic fungal infections. It is a lipid-based formulation of Amphotericin B, designed to enhance drug delivery and minimize side effects.

What are the possible side effects of AMFOEVA 50MG INJECTION?Arrow

While AMFOEVA 50MG INJECTION is generally well-tolerated, it can still have side effects. Common side effects may include fever, chills, headache, nausea, vomiting, increased blood sugar levels, muscle or joint pain, and infusion-related reactions. In rare cases, it may cause more serious side effects such as cardiac arrest, kidney damage or allergic reactions.

Can AMFOEVA 50MG INJECTION be used in pediatric patients?Arrow

AMFOEVA 50MG INJECTION can be used in babies more than 1 years old, but the dosage and administration may vary depending on the child's age, weight, and specific medical condition. It is crucial to follow the healthcare provider's instructions and closely monitor the child's response to treatment.

Why is AMFOEVA 50MG INJECTION less toxic?Arrow

AMFOEVA 50MG INJECTION is less toxic because it is less nephrotoxic. Low toxicity of this medicine may be due to the small number of binding receptors in the drug.

What are the advantages of using AMFOEVA 50MG INJECTION over other antifungal medications?Arrow

One of the key advantages of AMFOEVA 50MG INJECTION is its lower toxicity compared to conventional Amphotericin B. This makes it a preferred choice, especially for patients more susceptible to antifungal medications' side effects. Additionally, AMFOEVA 50MG INJECTION has a prolonged circulation time in the body, allowing for less frequent dosi

Does AMFOEVA 50MG INJECTION interact with other drugs?Arrow

No known negative interactions of AMFOEVA 50MG INJECTION with other drugs.

What advice should I be given regarding the use of AMFOEVA 50MG INJECTION?Arrow

This medicine may cause damage to the kidney. Inform your doctor if you have kidney problems. This injection may cause severe infusion reactions such as flushing, itching, sickness, swelling of the face, mouth, tongue and airways, difficulty breathing. Inform your physician immediately if you face any of these symptoms. It may be necessary to continue this medication for several weeks to several months in order to treat certain infections. Stopping the medication too early may result in a return of the infection.Tell your doctor if your condition lasts or gets worse.

What molecule/combination is used for making AMFOEVA 50MG INJECTION?Arrow

LIPOSOMAL AMPHOTERICIN B is molecule/combination used for making AMFOEVA 50MG INJECTION.

For what ailments/diseases/conditions is AMFOEVA 50MG INJECTION prescribed?Arrow

AMFOEVA 50MG INJECTION is prescribed for various fungal infections.

References

Book Icon

Gilead Sciences International Ltd, Electronic medicines compendium (emc), <a href="https://www.medicines.org.uk/emc/files/pil.1022.pdf"><u>https://www.medicines.org.uk/emc/files/pil.1022.pdf</u></a>

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Gilead Sciences, Inc, US Food and Drug Administration, <a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050740s016lbl.pdf"><u>https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050740s016lbl.pdf</u></a>

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Ratings & Review

Good. Provides medicines at reasonable rates.

Jiji Varughese

Reviewed on 08-02-2024

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(4/5)

Good representation and good communication to the cx very helpfull

Sunny Mack

Reviewed on 02-02-2024

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(5/5)

Reliable and accessible pharmacy. Courteous and helpful people.

Jigar Jani

Reviewed on 29-08-2023

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(5/5)

Excellent 👍👍👍

ashok badhala

Reviewed on 26-11-2022

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(5/5)

Best medicines, Timing and behaviour is very good for human beings

Gyan Rathore

Reviewed on 07-08-2023

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(5/5)


Marketer / Manufacturer Details

CONCORD BIOTECH LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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