AMPHONAT 50MG INJECTION
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AMPHONAT 50MG INJECTION
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AMPHONAT 50MG INJECTION

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AMPHONAT 50MG INJECTION

By NATCO PHARMA LIMITED

MRP

7142.86

₹6132

14.15 % OFF

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Product DetailsArrow

About AMPHONAT 50MG INJECTION

  • AMPHONAT 50MG INJECTION contains the active substance Liposomal Amphotericin B, an antifungal antibiotic used to treat fungal infections affecting deep body organs. It is also prescribed for patients with a high temperature and neutropenia (a reduced number of white blood cells) when a fungal infection is suspected. Additionally, it is used in the treatment of visceral leishmaniasis, a parasitic disease affecting certain individuals.
  • Prior to your first treatment, your doctor may administer a small dose of AMPHONAT 50MG INJECTION to assess for potential allergic reactions. It's crucial to inform your doctor if you are allergic to amphotericin B or any other ingredients in this medication. Disclose any history of severe allergic reactions, kidney or liver problems, or if you are currently undergoing dialysis. Also, inform your doctor if you have low potassium levels, as this medication can further affect potassium balance. Regular monitoring of kidney and liver function is essential during treatment with this medicine.
  • Each vial of this medicine contains sugar; therefore, it's imperative to inform your doctor if you have diabetes. Discuss any existing medical conditions and all medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before starting this treatment. The most common side effects include skin rash, low potassium levels, diarrhea, anemia, insomnia, and shortness of breath. This medicine is generally not recommended for babies under 1 month old due to the lack of sufficient safety data in this age group. Report any unusual or severe side effects to your doctor immediately. It's important to adhere to the prescribed dosage and treatment duration for optimal results and to minimize the risk of resistance development.
  • Furthermore, patients should be aware of the potential for infusion-related reactions, such as fever, chills, and nausea. These reactions can often be managed with premedication or by slowing the infusion rate. Staying well-hydrated during treatment can also help to minimize kidney-related side effects. Regular blood tests will be conducted to monitor your overall health and the effectiveness of the treatment.

Uses of AMPHONAT 50MG INJECTION

  • Fungal infections affecting one or more deep-seated organs within the body.
  • In cases of suspected fungal infections requiring diagnostic evaluation and treatment.
  • Treatment for visceral leishmaniasis, a parasitic disease affecting internal organs.

Side Effects of AMPHONAT 50MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Skin rash
  • Increased blood sugar levels
  • Decreased potassium levels
  • Diarrhea
  • Nausea, vomiting
  • Anemia
  • Insomnia
  • Shortness of breath
  • Fever, chills or shivering
  • Cardiac arrest
  • GI bleeding
  • Severe skin reactions
  • Acute kidney injury

Safety Advice for AMPHONAT 50MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant before receiving AMPHONAT 50MG INJECTION.

Dosage of AMPHONAT 50MG INJECTIONArrow

  • AMPHONAT 50MG INJECTION will be administered to you by a healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. The medication is delivered via intravenous infusion, which means it is slowly dripped into your vein. It is crucial that you do not attempt to self-administer this injection. The appropriate dosage and duration of your treatment will be determined by your doctor, taking into account several factors.
  • These factors include the severity of your condition, your body weight, and any other relevant medical considerations. Your doctor will carefully assess your individual needs to ensure you receive the most effective and safe treatment regimen. It is important to follow your doctor's instructions precisely regarding the frequency and timing of your infusions.
  • If you have any questions or concerns about your treatment plan, do not hesitate to discuss them with your doctor or nurse. They can provide you with additional information and address any anxieties you may have. Remember, open communication with your healthcare team is essential for a successful treatment outcome.

How to store AMPHONAT 50MG INJECTION?Arrow

  • Keep AMPHONAT 50MG INJ away from the reach of children and pets.
  • Store AMPHONAT 50MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of AMPHONAT 50MG INJECTIONArrow

  • AMPHONAT 50MG INJECTION is an antifungal medication that works by targeting the cell membranes of susceptible fungi. Its active ingredient binds specifically to ergosterol, a crucial component of fungal cell membranes. This binding disrupts the integrity of the membrane, leading to increased permeability. As a result, essential intracellular components leak out of the fungal cell, ultimately causing cell death. The medication's mechanism of action effectively eliminates the fungal infection by compromising the structural integrity and function of the fungal cells.
  • By selectively targeting ergosterol, AMPHONAT 50MG INJECTION minimizes harm to human cells, which do not contain this sterol. This selective action contributes to the drug's effectiveness in treating fungal infections while reducing the risk of significant side effects. The disruption of the fungal cell membrane is a critical step in eradicating the infection, making AMPHONAT 50MG INJECTION a valuable tool in antifungal therapy.
  • The effectiveness of AMPHONAT 50MG INJECTION relies on its ability to induce these membrane permeability changes and subsequent leakage, leading to fungal cell death. This targeted approach is essential for clearing fungal infections and restoring the patient's health.

How to use AMPHONAT 50MG INJECTIONArrow

  • AMPHONAT 50MG INJECTION is administered by a trained healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. It is delivered intravenously, meaning it is given through a drip directly into your vein. It is crucial that you do not attempt to self-administer this injection.
  • The dosage and duration of your treatment will be determined by your doctor. They will carefully consider several factors, including the severity of your condition, your body weight, and other relevant medical considerations. This ensures that you receive the most appropriate and effective treatment plan tailored to your individual needs.
  • During the intravenous infusion, the healthcare professional will closely monitor your condition for any potential side effects or complications. If you experience any discomfort or have any concerns during the infusion, it is important to inform them immediately. They are equipped to manage any issues that may arise and ensure your safety and well-being throughout the treatment process.
  • Following the administration of AMPHONAT 50MG INJECTION, your doctor will continue to monitor your progress and adjust the treatment plan as necessary. It is important to attend all scheduled follow-up appointments and communicate any changes in your condition or any new symptoms to your healthcare provider.

FAQs

What is AMPHONAT 50MG INJECTION?Arrow

AMPHONAT 50MG INJECTION is a medication used to treat severe fungal infections, such as invasive or systemic fungal infections. It is a lipid-based formulation of Amphotericin B, designed to enhance drug delivery and minimize side effects.

What are the possible side effects of AMPHONAT 50MG INJECTION?Arrow

While AMPHONAT 50MG INJECTION is generally well-tolerated, it can still have side effects. Common side effects may include fever, chills, headache, nausea, vomiting, increased blood sugar levels, muscle or joint pain, and infusion-related reactions. In rare cases, it may cause more serious side effects such as cardiac arrest, kidney damage or allergic reactions.

Can AMPHONAT 50MG INJECTION be used in pediatric patients?Arrow

AMPHONAT 50MG INJECTION can be used in babies more than 1 years old, but the dosage and administration may vary depending on the child's age, weight, and specific medical condition. It is crucial to follow the healthcare provider's instructions and closely monitor the child's response to treatment.

Why is AMPHONAT 50MG INJECTION less toxic?Arrow

AMPHONAT 50MG INJECTION is less toxic because it is less nephrotoxic. Low toxicity of this medicine may be due to the small number of binding receptors in the drug.

What are the advantages of using AMPHONAT 50MG INJECTION over other antifungal medications?Arrow

One of the key advantages of AMPHONAT 50MG INJECTION is its lower toxicity compared to conventional Amphotericin B. This makes it a preferred choice, especially for patients more susceptible to antifungal medications' side effects. Additionally, AMPHONAT 50MG INJECTION has a prolonged circulation time in the body, allowing for less frequent dosing.

Does AMPHONAT 50MG INJECTION interact with other drugs?Arrow

There is no known interaction of AMPHONAT 50MG INJECTION with other drugs.

What is the advice for using AMPHONAT 50MG INJECTION?Arrow

This medicine may cause damage to the kidney. Inform your doctor if you have kidney problems. This injection may cause severe infusion reactions such as flushing, itching, sickness, swelling of the face, mouth, tongue and airways, difficulty breathing. Inform your physician immediately if you face any of these symptoms. It may be necessary to continue this medication for several weeks to several months in order to treat certain infections. Stopping the medication too early may result in a return of the infection.Tell your doctor if your condition lasts or gets worse.

What is Liposomal Amphotericin B and how is it used to make AMPHONAT 50MG INJECTION?Arrow

Liposomal Amphotericin B is a type of Amphotericin B that is encapsulated in small, fat-like particles called liposomes. This helps to deliver the drug more effectively in the body and reduces side effects. AMPHONAT 50MG INJECTION is made using Liposomal Amphotericin B.

What types of infectious diseases are treated with AMPHONAT 50MG INJECTION?Arrow

AMPHONAT 50MG INJECTION is used to treat various types of infectious diseases.

References

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Gilead Sciences International Ltd, Electronic medicines compendium (emc)

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Gilead Sciences, Inc, US Food and Drug Administration

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(5/5)


Marketer / Manufacturer Details

NATCO PHARMA LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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