GUFISOME 50MG INJECTION
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GUFISOME 50MG INJECTION
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GUFISOME 50MG INJECTION

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GUFISOME 50MG INJECTION

By GUFIC BIOSCIENCE LIMITED

MRP

7443.81

₹4900

34.17 % OFF

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Product DetailsArrow

About GUFISOME 50MG INJECTION

  • GUFISOME 50MG INJECTION contains liposomal amphotericin B as its active ingredient, an antifungal antibiotic crucial for combating severe fungal infections. It is prescribed to treat fungal infections affecting deep body organs, ensuring targeted action against the infection. This injection is also valuable for individuals with a high fever and neutropenia (a reduced count of white blood cells), where a fungal infection is suspected.
  • Furthermore, GUFISOME 50MG INJECTION is effective in treating visceral leishmaniasis, a parasitic disease prevalent in certain populations. This demonstrates the injection’s versatility in addressing different types of infections. Prior to the commencement of treatment, your healthcare provider may administer a small dose of GUFISOME 50MG INJECTION to monitor for potential allergic reactions. It is crucial to inform your doctor if you are allergic to amphotericin B or any other components of this medication.
  • Inform your healthcare provider about any pre-existing conditions, such as severe allergic reactions, kidney or liver issues, or if you are undergoing dialysis. This information helps in tailoring the treatment plan to your specific needs. It's also important to disclose if you have low potassium levels. Since this medicine contains sugar, diabetic patients should exercise caution and inform their doctor. Discuss your pregnancy or breastfeeding status with your physician before starting GUFISOME 50MG INJECTION treatment.
  • Potential side effects of GUFISOME 50MG INJECTION may include skin rash, reduced potassium levels, diarrhea, anemia, insomnia, and shortness of breath. It is essential to be aware of these potential effects and report any concerns to your healthcare provider promptly. This medicine is generally not recommended for infants under the age of 1 month due to potential risks.

Uses of GUFISOME 50MG INJECTION

  • Fungal infections affecting one or more deep-seated organs within the body, potentially causing severe health complications.
  • Suspected fungal infections requiring thorough investigation and potentially treatment with GUFISOME 50MG INJECTION.
  • Visceral leishmaniasis, a parasitic disease affecting internal organs, may necessitate treatment.

Side Effects of GUFISOME 50MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. Common side effects include skin rash, increased blood sugar levels, decreased potassium levels, diarrhea, nausea and vomiting, anemia, insomnia, shortness of breath, and fever, chills, or shivering. Serious side effects may include cardiac arrest, GI bleeding, severe skin reactions, and acute kidney injury.

  • Skin rash
  • Increased blood sugar levels
  • Decreased potassium levels
  • Diarrhea
  • Nausea, vomiting
  • Anemia
  • Insomnia
  • Shortness of breath
  • Fever, chills or shivering
  • Cardia arrest
  • GI bleeding
  • Severe skin reactions
  • Acute kidney injury

Safety Advice for GUFISOME 50MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant before receiving GUFISOME 50MG INJECTION.

Dosage of GUFISOME 50MG INJECTIONArrow

  • GUFISOME 50MG INJECTION will be administered to you by a healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. It is delivered directly into your bloodstream through an intravenous infusion drip. It is crucial that you do not attempt to self-administer this injection.
  • The specific dosage and duration of your treatment will be determined by your doctor. They will carefully consider several factors, including the severity of your condition, your body weight, and other relevant health considerations. This ensures that you receive the most appropriate and effective treatment plan tailored to your individual needs.
  • It's important to adhere to the prescribed dosage and schedule provided by your doctor. If you have any questions or concerns about your treatment, don't hesitate to discuss them with your healthcare provider. They can provide further clarification and address any anxieties you may have.

How to store GUFISOME 50MG INJECTION?Arrow

  • Keep GUFISOME 50MG INJ away from the reach of children and pets.
  • Store GUFISOME 50MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of GUFISOME 50MG INJECTIONArrow

  • GUFISOME 50MG INJECTION is an antifungal medication that exerts its therapeutic effect by targeting ergosterol, a vital component of fungal cell membranes. Upon administration, the injection's active ingredient selectively binds to ergosterol within the membranes of susceptible fungi. This interaction disrupts the integrity and normal function of the cell membrane, leading to alterations in its permeability.
  • These permeability changes compromise the cell's ability to regulate the passage of substances in and out. Essential intracellular components, such as ions, proteins, and other vital molecules, begin to leak out of the fungal cell. This leakage disrupts the cell's internal environment, leading to a cascade of events that ultimately result in cell death.
  • The mechanism of action of GUFISOME 50MG INJECTION is crucial for its effectiveness in treating various fungal infections. By specifically targeting ergosterol, it minimizes the impact on human cells, which do not contain this compound. This targeted approach allows for the selective elimination of fungal pathogens while sparing healthy host cells.

How to use GUFISOME 50MG INJECTIONArrow

  • GUFISOME 50MG INJECTION is administered by a qualified healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. It is delivered intravenously through an infusion drip directly into your vein. It is crucial not to attempt self-administration of this medication.
  • The dosage and duration of treatment with GUFISOME 50MG INJECTION will be determined by your doctor, who will consider several factors. These include the severity of your condition, your body weight, and other relevant health considerations. They will carefully assess your individual needs to establish the most appropriate treatment plan for you.
  • During the infusion, your healthcare provider will closely monitor your response to the medication. This allows them to make any necessary adjustments to the infusion rate or dosage to ensure optimal effectiveness and minimize potential side effects. It's important to communicate any discomfort or concerns you may have during the process to your healthcare team.
  • Following the infusion, your doctor will evaluate the treatment's impact and decide on any further steps. Adhering to your doctor's instructions and attending all scheduled appointments is crucial for successful treatment outcomes. Remember, consistency in following the prescribed treatment plan is essential for achieving the best possible results.

FAQs

What is GUFISOME 50MG INJECTION?Arrow

GUFISOME 50MG INJECTION is a medication used to treat severe fungal infections, such as invasive or systemic fungal infections. It is a lipid-based formulation of Amphotericin B, designed to enhance drug delivery and minimize side effects.

What are the possible side effects of GUFISOME 50MG INJECTION?Arrow

While GUFISOME 50MG INJECTION is generally well-tolerated, it can still have side effects. Common side effects may include fever, chills, headache, nausea, vomiting, increased blood sugar levels, muscle or joint pain, and infusion-related reactions. In rare cases, it may cause more serious side effects such as cardiac arrest, kidney damage or allergic reactions.

Can GUFISOME 50MG INJECTION be used in pediatric patients?Arrow

GUFISOME 50MG INJECTION can be used in babies more than 1 years old, but the dosage and administration may vary depending on the child's age, weight, and specific medical condition. It is crucial to follow the healthcare provider's instructions and closely monitor the child's response to treatment.

Why is GUFISOME 50MG INJECTION less toxic?Arrow

GUFISOME 50MG INJECTION is less toxic because it is less nephrotoxic. Low toxicity of this medicine may be due to the small number of binding receptors in the drug.

What are the advantages of using GUFISOME 50MG INJECTION over other antifungal medications?Arrow

One of the key advantages of GUFISOME 50MG INJECTION is its lower toxicity compared to conventional Amphotericin B. This makes it a preferred choice, especially for patients more susceptible to antifungal medications' side effects. Additionally, GUFISOME 50MG INJECTION has a prolonged circulation time in the body, allowing for less frequent dosing.

Does GUFISOME 50MG INJECTION interact with other drugs?Arrow

There is no known interaction of GUFISOME 50MG INJECTION with other drugs.

What advice should I follow regarding the use of GUFISOME 50MG INJECTION?Arrow

This medicine may cause damage to the kidney. Inform your doctor if you have kidney problems. This injection may cause severe infusion reactions such as flushing, itching, sickness, swelling of the face, mouth, tongue and airways, difficulty breathing. Inform your physician immediately if you face any of these symptoms. It may be necessary to continue this medication for several weeks to several months in order to treat certain infections. Stopping the medication too early may result in a return of the infection.Tell your doctor if your condition lasts or gets worse.

What molecule/combination is used for making GUFISOME 50MG INJECTION?Arrow

LIPOSOMAL AMPHOTERICIN B is the molecule/combination used for making GUFISOME 50MG INJECTION.

For which ailments/diseases/conditions is GUFISOME 50MG INJECTION prescribed?Arrow

GUFISOME 50MG INJECTION is prescribed for Infectious Diseases.

References

Book Icon

Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Chemotherapy of protozoal infections, 12th edition, 2011, 1424.

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KD Tripathi, Essentials of Medical Pharmacology, Antifungal drugs, 7th edition, 2013, 787-788.

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Gilead Sciences International Ltd, Electronic medicines compendium (emc),

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Gilead Sciences, Inc, US Food and Drug Administration,

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GUFIC BIOSCIENCE LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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