AMLOVAS L TABLET 15'S

How AMLOVAS L TABLET 15'S Works

• AMLOVAS L Tablet 15'S is a combination medication designed to manage hypertension (high blood pressure) effectively. It combines Amlodipine and Lisinopril, each contributing uniquely to lowering blood pressure.
• Amlodipine is a calcium channel blocker. It works by relaxing and widening blood vessels, allowing blood to flow more easily. Specifically, it inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle. By blocking calcium entry, Amlodipine reduces the contraction of these muscles, leading to vasodilation (widening of blood vessels). This vasodilation decreases peripheral vascular resistance, reducing the workload on the heart and lowering blood pressure. Amlodipine primarily affects arterial smooth muscle, making it effective in reducing afterload (the resistance the heart pumps against).
• Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking the production of angiotensin II, a powerful vasoconstrictor (a substance that narrows blood vessels). ACE inhibitors prevent the conversion of angiotensin I to angiotensin II. By reducing angiotensin II levels, Lisinopril promotes vasodilation, which lowers blood pressure. Additionally, angiotensin II stimulates the release of aldosterone, a hormone that causes the kidneys to retain sodium and water. By inhibiting angiotensin II, Lisinopril reduces aldosterone levels, leading to increased sodium and water excretion, further contributing to lower blood pressure. Lisinopril also has beneficial effects on the heart, particularly in heart failure, by reducing preload (the volume of blood in the heart at the end of diastole) and afterload.
• The combined effect of Amlodipine and Lisinopril provides a synergistic approach to blood pressure management. Amlodipine's vasodilation complements Lisinopril's reduction of angiotensin II and aldosterone levels. This combination is particularly useful for patients who require more than one medication to control their hypertension. The complementary mechanisms of action help to achieve better blood pressure control compared to using either medication alone.
• In summary, AMLOVAS L Tablet 15'S works by Amlodipine relaxing blood vessels and Lisinopril preventing the formation of a substance that narrows blood vessels and causes salt and water retention. This dual action effectively lowers blood pressure and reduces the strain on the heart, making it a valuable treatment option for hypertension.

Common side effects of AMLOVAS L Tablet may include: Dizziness, Headache, Fatigue, Sleepiness, Palpitations, Flushing (sense of warmth in the face, ears, neck and trunk), Ankle swelling, Abdominal pain, Nausea, Edema (swelling), Increased heart rate, Muscle pain, Orthostatic hypotension (sudden lowering of blood pressure on standing), Visual disturbance. Less common or rare side effects may include: Mood changes, Anxiety, Depression, Tremor, Taste changes, Numbness or tingling sensation, Dry mouth, Increased sweating, Skin rash, Hair loss, Impotence, Gynecomastia (enlargement of breasts in men), Allergic reactions, Liver problems, Changes in blood counts.

• If you miss a dose of AMLOVAS L Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep AMLOVAS L TAB 1X15 away from the reach of children and pets.
• Store AMLOVAS L TAB 1X15 at room temperature.

• Take AMLOVAS L TABLET 15'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking it without consulting your physician, as this could lead to serious health complications. Consistency is key for managing your blood pressure and cholesterol levels effectively.
• AMLOVAS L TABLET 15'S is often most effective when taken at the same time each day. Choose a time that fits easily into your daily routine to help you remember to take it regularly. This helps maintain a stable level of medication in your body.
• Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking. AMLOVAS L TABLET 15'S can interact with other substances, potentially reducing its effectiveness or increasing the risk of side effects. Be transparent about your complete medication list.
• Follow a heart-healthy lifestyle while taking AMLOVAS L TABLET 15'S. This includes a balanced diet low in saturated fats, cholesterol, and sodium, regular exercise, and avoiding smoking. These lifestyle changes can significantly enhance the benefits of the medication.
• Be aware of potential side effects such as dizziness, lightheadedness, or swelling in your ankles or feet. If you experience any persistent or bothersome side effects, contact your doctor promptly. They can provide guidance on managing these effects or adjusting your treatment plan if necessary.

• AMLOVAS L TABLET 15'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent drug levels in the body.
• Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medication, as it may increase the levels of amlodipine in your blood and potentially increase side effects.