AMTAS LP TABLET 10'S

How AMTAS LP TABLET 10'S Works

• AMTAS LP TABLET 10'S is a combination medication designed to manage hypertension (high blood pressure) and reduce the risk of cardiovascular events. It combines amlodipine, losartan, and hydrochlorothiazide, each working through different mechanisms to achieve a comprehensive effect.
• Amlodipine, a calcium channel blocker, primarily targets the blood vessels. It inhibits the influx of calcium ions into vascular smooth muscle cells and cardiac muscle cells. This inhibition causes the smooth muscles of the blood vessels to relax, leading to vasodilation (widening of blood vessels). By reducing the constriction of blood vessels, amlodipine decreases peripheral vascular resistance, which in turn lowers blood pressure. Amlodipine's effects are gradual and sustained, providing consistent blood pressure control throughout the day. It also reduces the workload on the heart, making it easier for the heart to pump blood.
• Losartan, an angiotensin II receptor blocker (ARB), focuses on the renin-angiotensin-aldosterone system (RAAS). Angiotensin II is a potent vasoconstrictor that also stimulates the release of aldosterone, which promotes sodium and water retention. Losartan blocks the angiotensin II receptors, preventing angiotensin II from exerting its effects. This results in vasodilation, reduced aldosterone release, and decreased sodium and water reabsorption by the kidneys. By blocking the RAAS, losartan effectively lowers blood pressure and provides renal protection, making it particularly beneficial for patients with hypertension and kidney disease.
• Hydrochlorothiazide, a thiazide diuretic, acts on the kidneys to increase the excretion of sodium and water. It inhibits the sodium-chloride symporter in the distal convoluted tubule of the nephron, reducing sodium reabsorption. As sodium is excreted, water follows, leading to a decrease in blood volume. This reduction in blood volume contributes to lowering blood pressure. Over time, hydrochlorothiazide also causes vasodilation, further aiding in blood pressure control. Its diuretic effect helps to remove excess fluid from the body, alleviating symptoms of fluid overload often associated with hypertension.
• The synergistic action of these three components allows AMTAS LP TABLET 10'S to provide effective and comprehensive blood pressure management. Amlodipine relaxes blood vessels, losartan blocks the effects of angiotensin II, and hydrochlorothiazide reduces blood volume. This multi-pronged approach helps to achieve optimal blood pressure control, reduce the risk of stroke, heart attack, and kidney damage, and improve overall cardiovascular health. The combination is particularly useful for individuals who require multiple medications to manage their hypertension effectively.

Common side effects of AMTAS LP Tablet may include nausea, vomiting, stomach pain, heartburn, diarrhea, constipation, loss of appetite, dizziness, headache, fatigue, and swelling in the ankles or feet. Less common side effects could be skin rash, itching, difficulty breathing, changes in liver function tests, increased heart rate, palpitations, muscle cramps, and sleep disturbances. Rare but serious side effects include liver damage, allergic reactions (anaphylaxis), and gastrointestinal bleeding. Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of AMTAS LP TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep AMTAS LP TAB 1X10 away from the reach of children and pets.
• Store AMTAS LP TAB 1X10 at room temperature.

• Take AMTAS LP Tablet 10'S exactly as prescribed by your doctor. Do not self-medicate or change the dosage without consulting your healthcare provider. Consistent timing is key for optimal results.
• AMTAS LP Tablet 10'S is often prescribed to manage conditions like hypertension and/or angina. Regularly monitor your blood pressure and follow your doctor's advice on diet and exercise to maximize the medicine's effectiveness. Keep a record of your readings to share with your doctor.
• Be aware of potential side effects such as dizziness, lightheadedness, or swelling in the ankles and feet. If these symptoms become bothersome or severe, contact your doctor immediately. Do not abruptly stop taking AMTAS LP Tablet 10'S, as this can cause serious health issues.
• Store AMTAS LP Tablet 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children. Check the expiration date before using and properly dispose of any expired medication.
• Inform your doctor about all other medications, supplements, or herbal remedies you are currently taking before starting AMTAS LP Tablet 10'S. This helps prevent potential drug interactions and ensures your doctor can provide the safest and most effective treatment plan. Especially, mention if you are taking any other blood pressure medications.

• AMTAS LP TABLET 10'S can be taken with or without food. However, it is important to take the medicine at the same time each day to maintain consistent blood levels. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medication, as it may increase the blood levels of amlodipine and potentially increase side effects. If you have any specific dietary concerns, consult your doctor or pharmacist.