APOTINIB 400 TABLET 10'S
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APOTINIB 400 TABLET 10'S
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APOTINIB 400 TABLET 10'S

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APOTINIB 400 TABLET 10'S

By BDR PHARMACEUTICALS INTERNATIONALS PVT LTD

MRP

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1869.32

₹598

68.01 % OFF

₹59.8 Only /

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About APOTINIB 400 TABLET 10'S

  • APOTINIB 400 TABLET 10'S contains the active substance imatinib, an antineoplastic drug belonging to the tyrosine kinase inhibitor class. It is prescribed for adults and children with chronic myeloid leukemia (CML), a type of leukemia where abnormal white blood cells proliferate uncontrollably. It is also used in treating Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL) and certain types of gastrointestinal stromal tumors (GIST), which are tumors developing in the digestive tract walls that may metastasize.
  • APOTINIB 400 TABLET 10'S is further indicated for myelodysplastic/myeloproliferative diseases (MDS/MPD), a group of blood disorders characterized by uncontrolled blood cell growth. It also treats hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukemia (CEL), blood diseases involving uncontrolled eosinophil proliferation. Additionally, this medication is used for dermatofibrosarcoma protuberans (DFSP), a skin tissue cancer marked by abnormal cell growth. It functions by suppressing the growth of these aberrant blood cells.
  • Before taking APOTINIB 400 TABLET 10'S, inform your doctor if you are allergic to imatinib or any of its components. Disclose any existing kidney, heart, liver, or thyroid problems, or if your thyroid gland has been removed. Report any history of hepatitis B infection, as this medication can reactivate the virus. Be vigilant for symptoms like bruising, bleeding, fever, fatigue, and confusion while on this medication. This medicine may impair fertility. If you experience any persistent or worsening side effects, seek immediate medical attention. Regular monitoring by your healthcare provider is crucial during treatment with this medication to assess its effectiveness and manage any potential complications. Always follow your doctor's instructions regarding dosage and duration of treatment.

Uses of APOTINIB 400 TABLET 10'S

  • Chronic myeloid leukemia (CML), a type of cancer that affects the blood and bone marrow, characterized by the overproduction of white blood cells.
  • Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL), a specific subtype of acute lymphoblastic leukemia associated with the presence of the Philadelphia chromosome.
  • Myelodysplastic/myeloproliferative diseases (MDS/MPD), a group of clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis and a propensity to transform into acute myeloid leukemia.
  • Hypereosinophilic syndrome (HES), a rare disorder characterized by a persistently elevated eosinophil count in the blood, leading to organ damage.
  • Chronic eosinophilic leukemia (CEL), a myeloproliferative neoplasm characterized by a sustained increase in eosinophils in the blood and bone marrow.
  • Dermatofibrosarcoma protuberans (DFSP), a rare type of skin cancer that grows slowly and can recur after treatment. APOTINIB 400 TABLET 10'S may be used in its treatment.
  • Gastrointestinal stromal tumors (GIST), tumors that occur in the digestive tract; APOTINIB 400 TABLET 10'S might be used for treating it.

Side Effects of APOTINIB 400 TABLET 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. APOTINIB 400 TABLET 10'S can cause the following side effects:

  • Swelling in the face, legs, ankles, and feet
  • Nausea, vomiting
  • Muscle cramps and pain
  • Diarrhea
  • Skin rash, night sweats
  • Tiredness, dizziness
  • Abdominal pain
  • Increased weight
  • Decreased RBC and WBC cells
  • Headache
  • Cough, Inflammation in the nose
  • Fever, lack of sleep
  • Heart failure
  • GI disorders
  • Hypothyroidism
  • Liver failure
  • Swelling in the body

Safety Advice for APOTINIB 400 TABLET 10'SArrow

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Pregnancy

UNSAFE

APOTINIB 400 TABLET 10'S is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 15 days after your last dose is necessary.

Dosage of APOTINIB 400 TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with APOTINIB 400 TABLET 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to adhere strictly to your doctor's instructions regarding the dosage and timing of the medication.
  • Administer APOTINIB 400 TABLET 10'S orally, exactly as prescribed. Do not alter the form of the tablet by breaking, crushing, or chewing it. These actions can affect how the medication is absorbed and could potentially reduce its effectiveness or increase the risk of side effects. Instead, swallow the tablet whole with a full glass of water.
  • Taking APOTINIB 400 TABLET 10'S with a meal is generally recommended to minimize the possibility of stomach upset or gastrointestinal discomfort. Food can help to buffer the medication and reduce irritation to the stomach lining. However, if you experience persistent stomach problems despite taking the medication with food, consult your doctor.
  • If you have difficulty swallowing tablets, discuss alternative administration methods with your doctor. In some cases, it may be possible to dissolve the tablet in water or another suitable liquid. Always follow your doctor's specific instructions for dissolving and taking the medication to ensure that you receive the correct dose and that the medication remains effective.

How to store APOTINIB 400 TABLET 10'S?Arrow

  • Keep APOTINIB 400MG TAB 1X10 away from the reach of children and pets.
  • Store APOTINIB 400MG TAB 1X10 at room temperature.

Benefits of APOTINIB 400 TABLET 10'SArrow

  • APOTINIB 400 TABLET 10'S is a targeted cancer therapy that belongs to a class of drugs called protein-tyrosine kinase inhibitors. It works by specifically targeting and blocking the activity of abnormal proteins, particularly those created due to chromosomal abnormalities, that drive the uncontrolled growth and division of cancer cells. By inhibiting these proteins, APOTINIB 400 TABLET 10'S effectively disrupts the signaling pathways that fuel cancer cell proliferation.
  • This targeted action not only slows down the multiplication of cancerous cells but also promotes cell death (apoptosis) in these abnormal cells. APOTINIB 400 TABLET 10'S is designed to selectively target cancer cells, minimizing damage to healthy cells in the body, which can lead to fewer side effects compared to traditional chemotherapy.
  • APOTINIB 400 TABLET 10'S is typically prescribed for specific types of cancer where the abnormal protein targeted by the drug is present. Treatment with APOTINIB 400 TABLET 10'S can help manage the disease, improve quality of life, and potentially extend survival in patients with these cancers. It's crucial to use this medication under the guidance of an oncologist who can monitor its effectiveness and manage any potential side effects.

How to use APOTINIB 400 TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with APOTINIB 400 TABLET 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to adhere strictly to your doctor's prescribed dosage and schedule.
  • Administer APOTINIB 400 TABLET 10'S orally, following your doctor's instructions precisely. Avoid altering the tablet in any way; do not break, crush, or chew it. Swallow the tablet whole with a full glass of water to ensure proper absorption and prevent any potential irritation to your throat.
  • To minimize the risk of stomach upset or other gastrointestinal issues, it is generally recommended to take APOTINIB 400 TABLET 10'S with a meal. This can help buffer the medication's effects on your digestive system. If you experience persistent stomach problems, consult your doctor for further guidance.
  • In cases where swallowing the tablets whole poses a challenge, consult your doctor for alternative methods of administration. They may advise dissolving the tablet in water or another suitable liquid. Follow their specific instructions carefully to ensure you receive the correct dosage and maintain the medication's effectiveness.

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ONTINIB 400MG TAB 1X10ZEE LABORATORIES LTD102362.52362.50
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IMANEX 400MG TAB 1X10METTA LIFE SCIENCES PVT LTD102362.549978.88
IMANIB 400MG TAB 1X10INTAS PHARMACEUTICALS LIMITED102132.4589957.84
IBATKIN 400MG TAB 1X10ZUVENTUS HEALTHCARE LIMITED102265.74193314.69
GLIVEC 400MG TAB 1X10NOVARTIS INDIA LIMITED102274.542274.540

FAQs

How to use APOTINIB 400 TABLET 10'S?Arrow

APOTINIB 400 TABLET 10'S is administered orally, in the form of a tablet or capsule, and the dose depends on several factors, including the condition being treated, the weight of the patient, the particular regimen being used, and the overall health of the patient. It should be taken with food and a large glass of water to minimize gastrointestinal irritation.

Ever since I started using APOTINIB 400 TABLET 10'S, I have noticed rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?Arrow

This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness, or severe sunburn. When you are outdoors, wear protective clothing and use sunscreen with an SPF. Consult your doctor before taking necessary precautions.

Can APOTINIB 400 TABLET 10'S cause kidney damage?Arrow

Yes, when taken for a longer period the medicine may cause damage to your kidneys. Your doctors may recommend you take a routine blood tests to assess your kidney function.

When is the best time to take APOTINIB 400 TABLET 10'S?Arrow

Take the tablet as prescribed by your doctor. Take APOTINIB 400 TABLET 10'S at the same time every day. It is usually taken with a meal and a large glass of water to avoid stomach problems.

Does APOTINIB 400 TABLET 10'S affect memory?Arrow

Memory impairments have been only reported in limited studies. Consult your doctor immediately if you have any trouble in concentrating.

Does APOTINIB 400 TABLET 10'S interact with other drugs?Arrow

There are no known interactions of APOTINIB 400 TABLET 10'S with other drugs.

What precautions should I take while taking APOTINIB 400 TABLET 10'S?Arrow

You may become more sensitive to the sun while taking APOTINIB 400 TABLET 10'S. It is important to cover sun-exposed areas of skin and use sunscreen with a high sun protection factor after consulting with your doctor. The medicine should be administered cautiously in patients with kidney problems. This tablet may cause your body to retain water, inform your physician if you put on weight very quickly after the therapy. Your doctor will regularly do lab tests to check whether the medicine works. Do not breastfeed during the treatment with this medicine and for 15 days after your last dose.

What is APOTINIB 400 TABLET 10'S made of?Arrow

IMATINIB is the molecule/combination used for making APOTINIB 400 TABLET 10'S.

For which ailments/diseases/conditions is APOTINIB 400 TABLET 10'S prescribed?Arrow

APOTINIB 400 TABLET 10'S is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Imatinib 400mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk.

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Marketer / Manufacturer Details

BDR PHARMACEUTICALS INTERNATIONALS PVT LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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