ONTINIB 400 TABLET 10'S
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ONTINIB 400 TABLET 10'S
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ONTINIB 400 TABLET 10'S

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ONTINIB 400 TABLET 10'S

By ZEE LABORATORIES LTD

MRP

2520

₹2520

₹252 Only /

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10

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Product DetailsArrow

About ONTINIB 400 TABLET 10'S

  • ONTINIB 400 TABLET 10'S contains the active substance imatinib, an antineoplastic drug belonging to the tyrosine kinase inhibitor class. It is prescribed for adults and children with chronic myeloid leukemia (CML), a leukemia characterized by uncontrolled growth of abnormal white blood cells. It also treats Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL) and certain gastrointestinal stromal tumors (GIST), tumors in the digestive tract walls that can spread.
  • ONTINIB 400 TABLET 10'S is also indicated for myelodysplastic/myeloproliferative diseases (MDS/MPD), a group of blood disorders causing abnormal blood cell growth. Additionally, it treats hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukemia (CEL), blood diseases marked by uncontrolled eosinophil growth. This medication is also used for dermatofibrosarcoma protuberans (DFSP), a skin tissue cancer with abnormal cell growth. Imatinib inhibits the proliferation of these abnormal blood cells, helping to manage these conditions.
  • Before starting ONTINIB 400 TABLET 10'S, inform your doctor if you have kidney, heart, liver, or thyroid problems, including thyroid gland removal. Disclose any past or present hepatitis B infection, as this medication can reactivate the virus. Immediately report symptoms like bruising, bleeding, fever, fatigue, or confusion. This medicine may impair fertility, so discuss family planning with your doctor. Regular monitoring and adherence to your doctor's instructions are crucial for successful treatment.
  • It is crucial to adhere to the prescribed dosage and schedule provided by your healthcare provider. Do not abruptly stop taking this medication without consulting your doctor, as this could lead to a relapse of your condition. Regular blood tests and check-ups will be necessary to monitor your body's response to ONTINIB 400 TABLET 10'S and to identify any potential side effects early on. Report any unusual symptoms or side effects to your doctor promptly.

Uses of ONTINIB 400 TABLET 10'S

  • Chronic myeloid leukemia (CML) is a type of cancer that starts in the blood-forming cells of the bone marrow and then invades the blood.
  • Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL) is a type of acute leukemia where the leukemia cells contain an abnormal chromosome called the Philadelphia chromosome.
  • Myelodysplastic/myeloproliferative diseases (MDS/MPD) are a group of blood cancers in which the bone marrow makes too many abnormal blood cells.
  • Hypereosinophilic syndrome (HES) is a group of disorders characterized by a persistently elevated number of eosinophils in the blood, which can damage various organs.
  • Chronic eosinophilic leukemia (CEL) is a rare type of blood cancer in which there is an overproduction of eosinophils, leading to organ damage and other complications.
  • Dermatofibrosarcoma protuberans (DFSP) is a rare type of skin cancer that grows slowly and can recur even after treatment.
  • Gastrointestinal stromal tumors (GISTs) are tumors that occur in the digestive tract. ONTINIB 400 TABLET 10'S may be used in treating such conditions.

Side Effects of ONTINIB 400 TABLET 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the face, legs, ankles, and feet
  • Nausea, vomiting
  • Muscle cramps and pain
  • Diarrhea
  • Skin rash, night sweats
  • Tiredness, dizziness
  • Abdominal pain
  • Increased weight
  • Decreased RBC and WBC cells
  • Headache
  • Cough, Inflammation in the nose
  • Fever, lack of sleep
  • Heart failure
  • GI disorders
  • Hypothyroidism
  • Liver failure
  • Swelling in the body

Safety Advice for ONTINIB 400 TABLET 10'SArrow

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Pregnancy

UNSAFE

ONTINIB 400 TABLET 10'S is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 15 days after your last dose is necessary.

Dosage of ONTINIB 400 TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with ONTINIB 400 TABLET 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to adhere strictly to your doctor's instructions regarding the intake of these tablets.
  • Administer ONTINIB 400 TABLET 10'S exactly as prescribed by your healthcare provider. Avoid breaking, crushing, or chewing the tablets, as this could affect the way the medication is absorbed and utilized by your body. The tablets should be swallowed whole with a sufficient amount of water.
  • To minimize the risk of stomach upset or irritation, it is generally recommended to take ONTINIB 400 TABLET 10'S with a meal. This can help to buffer the medication and reduce potential gastrointestinal side effects.
  • If you experience difficulty swallowing the tablets whole, consult with your doctor. They may provide guidance on alternative methods of administration, such as dissolving the tablet in water, if appropriate for this medication. Follow their specific instructions carefully.

How to store ONTINIB 400 TABLET 10'S?Arrow

  • Keep ONTINIB 400MG TAB 1X10 away from the reach of children and pets.
  • Store ONTINIB 400MG TAB 1X10 at room temperature.

Benefits of ONTINIB 400 TABLET 10'SArrow

  • ONTINIB 400 TABLET 10'S is a targeted cancer therapy that specifically inhibits the activity of a protein called tyrosine kinase. This protein plays a crucial role in the growth and spread of certain types of cancer cells. By blocking tyrosine kinase, ONTINIB 400 TABLET 10'S effectively disrupts the signaling pathways that fuel cancer cell proliferation.
  • This medication works by targeting an abnormal protein produced due to a chromosomal abnormality found in some cancer cells. This abnormal protein sends signals that tell the cancer cells to multiply uncontrollably. ONTINIB 400 TABLET 10'S directly interferes with this signal, preventing the cancer cells from receiving the instructions to divide and grow.
  • ONTINIB 400 TABLET 10'S not only inhibits the multiplication of abnormal cancer cells but also promotes their death. By disrupting the cellular processes necessary for survival, this medication encourages the cancer cells to undergo programmed cell death, also known as apoptosis. This dual action helps to reduce the number of cancerous cells in the body and slow down the progression of the disease.
  • Essentially, ONTINIB 400 TABLET 10'S acts as a precise inhibitor, selectively targeting and neutralizing the specific protein responsible for driving the uncontrolled growth of cancer cells. This targeted approach minimizes harm to healthy cells, reducing the potential for severe side effects often associated with traditional chemotherapy.

How to use ONTINIB 400 TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration of ONTINIB 400 TABLET 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to adhere strictly to your doctor's prescription regarding the dosage and timing of the medication.
  • Administer ONTINIB 400 TABLET 10'S exactly as prescribed by your healthcare provider. To ensure proper absorption and effectiveness, do not break, crush, or chew the tablets. Instead, swallow the tablet whole with a full glass of water.
  • To minimize the risk of stomach upset or gastrointestinal discomfort, it is advisable to take ONTINIB 400 TABLET 10'S with a meal. This helps to buffer the medication and promote better tolerance.
  • If you experience difficulty swallowing the tablets whole, consult your doctor for alternative administration methods. In some cases, your doctor may advise you to dissolve the tablet in water or another suitable liquid. Follow your doctor's specific instructions carefully for dissolving and taking the medication.
  • Consistent and correct usage of ONTINIB 400 TABLET 10'S as directed by your physician is essential for achieving the best possible therapeutic outcome. Do not alter the dosage or discontinue the medication without first consulting your doctor.

FAQs

How to use ONTINIB 400 TABLET 10'S?Arrow

ONTINIB 400 TABLET 10'S is administered orally, in the form of a tablet or capsule, and the dose depends on several factors, including the condition being treated, the weight of the patient, the particular regimen being used, and the overall health of the patient. It should be taken with food and a large glass of water to minimize gastrointestinal irritation.

Ever since I started using ONTINIB 400 TABLET 10'S, I have noticed rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?Arrow

This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness, or severe sunburn. When you are outdoors, wear protective clothing and use sunscreen with an SPF. Consult your doctor before taking necessary precautions.

Can ONTINIB 400 TABLET 10'S cause kidney damage?Arrow

Yes, when taken for a longer period the medicine may cause damage to your kidneys. Your doctors may recommend you take a routine blood tests to assess your kidney function.

When is the best time to take ONTINIB 400 TABLET 10'S?Arrow

Take the tablet as prescribed by your doctor. Take ONTINIB 400 TABLET 10'S at the same time every day. It is usually taken with a meal and a large glass of water to avoid stomach problems.

Does ONTINIB 400 TABLET 10'S affect memory?Arrow

Memory impairments have been only reported in limited studies. Consult your doctor immediately if you have any trouble in concentrating.

Does ONTINIB 400 TABLET 10'S interact with other drugs?Arrow

NULL interaction of ONTINIB 400 TABLET 10'S with other drugs

What advice should I follow while taking ONTINIB 400 TABLET 10'S?Arrow

You may become more sensitive to the sun while taking ONTINIB 400 TABLET 10'S. It is important to cover sun-exposed areas of skin and use sunscreen with a high sun protection factor after consulting with your doctor. The medicine should be administered cautiously in patients with kidney problems. This tablet may cause your body to retain water, inform your physician if you put on weight very quickly after the therapy. Your doctor will regularly do lab tests to check whether the medicine works. Do not breastfeed during the treatment with this medicine and for 15 days after your last dose.

What is ONTINIB 400 TABLET 10'S made of?Arrow

IMATINIB is molecule/combination used for making ONTINIB 400 TABLET 10'S.

For what type of cancer is ONTINIB 400 TABLET 10'S prescribed?Arrow

ONTINIB 400 TABLET 10'S is prescribed for Oncology ailments/diseases/conditions.

Is ONTINIB 400 TABLET 10'S a chemotherapy drug?Arrow

ONTINIB 400 TABLET 10'S is a targeted therapy, which is different from chemotherapy. It works by targeting cancer cells.

References

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Imatinib 400mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk.

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HIGHLIGHTS OF PRESCRIBING INFORMATION.

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Marketer / Manufacturer Details

ZEE LABORATORIES LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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