IMATINATE 400 CAPSULE 30'S
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IMATINATE 400 CAPSULE 30'S
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IMATINATE 400 CAPSULE 30'S

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IMATINATE 400 CAPSULE 30'S

By KHANDELWAL LABORATORIES PRIVATE LIMITED

MRP

₹

8305.69

₹1500

81.94 % OFF

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CAPSULE

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About IMATINATE 400 CAPSULE 30'S

  • IMATINATE 400 CAPSULE 30'S contains the active substance imatinib, an antineoplastic drug belonging to the tyrosine kinase inhibitor class. This medication is prescribed for adults and children diagnosed with chronic myeloid leukemia (CML), a type of leukemia characterized by the uncontrolled growth of abnormal white blood cells. It is also used in the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL). Additionally, IMATINATE 400 CAPSULE 30'S is effective against certain gastrointestinal stromal tumors (GIST), which are tumors that develop in the digestive tract walls and may spread throughout the body.
  • IMATINATE 400 CAPSULE 30'S is also indicated for myelodysplastic/myeloproliferative diseases (MDS/MPD), a group of blood disorders marked by the excessive growth of certain blood cells. Furthermore, it treats hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukemia (CEL), blood disorders involving the uncontrolled growth of eosinophils (a type of white blood cell). This medicine is also used to treat dermatofibrosarcoma protuberans (DFSP), a type of cancer affecting the tissue under the skin, characterized by abnormal cell growth. Imatinib works by inhibiting the growth and spread of these abnormal cells, effectively targeting the underlying cause of these conditions. Regular monitoring and adherence to the prescribed dosage are crucial for optimal therapeutic outcomes.
  • Before starting treatment with IMATINATE 400 CAPSULE 30'S, inform your doctor if you have any allergies to imatinib or any other components of the medication. Disclose any pre-existing kidney, heart, liver, or thyroid problems, including if your thyroid gland has been removed. It's vital to notify your doctor if you have a history of hepatitis B infection, as this medication can reactivate the virus. Be vigilant for symptoms like bruising, bleeding, fever, fatigue, and confusion, and report them to your doctor immediately. This medicine may impair fertility. It is important for patients to openly communicate with their healthcare provider about their medical history and any concerns they may have regarding treatment. Open communication ensures patient safety and allows for personalized adjustments to the treatment plan.
  • It is important to note that grapefruit and grapefruit juice should be avoided while taking this medication as they can interact with imatinib and potentially alter its effects. Also, be sure to discuss all other medications, supplements, and herbal remedies you are currently taking with your doctor, as drug interactions can occur. Consistent monitoring of blood counts and liver function is usually performed during treatment with IMATINATE 400 CAPSULE 30'S to check its effectiveness and identify any potential side effects early on.

Uses of IMATINATE 400 CAPSULE 30'S

  • Chronic myeloid leukemia (CML) is a type of cancer that affects the blood and bone marrow. It's characterized by the overproduction of white blood cells.
  • Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL) is a specific subtype of ALL where the leukemia cells have an abnormal chromosome called the Philadelphia chromosome.
  • Myelodysplastic/myeloproliferative diseases (MDS/MPN) are a group of disorders where the bone marrow doesn't produce enough healthy blood cells, and there may be an overproduction of certain blood cells.
  • Hypereosinophilic syndrome (HES) is a rare disorder characterized by a persistently elevated number of eosinophils (a type of white blood cell) in the blood.
  • Chronic eosinophilic leukemia (CEL) is a type of blood cancer where there is a persistent increase in eosinophils in the bone marrow and blood.
  • Dermatofibrosarcoma protuberans (DFSP) is a rare type of skin cancer that grows slowly and can recur after treatment.
  • Gastrointestinal stromal tumors (GISTs) are tumors that occur in the digestive tract. These tumors start in specialized cells in the wall of the gastrointestinal tract.

Side Effects of IMATINATE 400 CAPSULE 30'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common side effects may include swelling in the face, legs, ankles, and feet, nausea, vomiting, muscle cramps and pain, diarrhea, skin rash, night sweats, tiredness, dizziness, abdominal pain, increased weight, decreased RBC and WBC cells, headache, cough, inflammation in the nose, fever, and lack of sleep. Serious side effects may include heart failure, GI disorders, hypothyroidism, and liver failure, swelling in the body.

  • Swelling in the face, legs, ankles, and feet
  • Nausea, vomiting
  • Muscle cramps and pain
  • Diarrhea
  • Skin rash, night sweats
  • Tiredness, dizziness
  • Abdominal pain
  • Increased weight
  • Decreased RBC and WBC cells
  • Headache
  • Cough, Inflammation in the nose
  • Fever, lack of sleep
  • Heart failure
  • GI disorders
  • Hypothyroidism
  • Liver failure
  • Swelling in the body

Safety Advice for IMATINATE 400 CAPSULE 30'SArrow

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Pregnancy

UNSAFE

IMATINATE 400 CAPSULE 30'S is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 15 days after your last dose is necessary.

Dosage of IMATINATE 400 CAPSULE 30'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with IMATINATE 400 CAPSULE 30'S based on your specific medical condition, its severity, and other individual factors. It is crucial to strictly adhere to your doctor's prescribed instructions regarding the medication. These tablets should be taken exactly as directed by your healthcare provider.
  • To ensure optimal absorption and minimize potential gastrointestinal discomfort, it is generally recommended to take IMATINATE 400 CAPSULE 30'S with a meal. This can help to reduce the likelihood of experiencing stomach upset or other digestive issues. If you have a sensitive stomach, this is particularly important.
  • Do not break, crush, or chew the tablets. These tablets are designed to be swallowed whole to ensure the medication is released properly within your body. Breaking or altering the tablet can affect how the medication is absorbed and may reduce its effectiveness. Swallow the tablet whole with a full glass of water to aid in swallowing and ensure proper delivery to the stomach.
  • If you experience difficulty swallowing the tablets whole, consult your doctor or pharmacist for alternative administration methods. In some cases, your doctor may advise dissolving the tablets in water or another suitable liquid. However, it's essential to follow your doctor's specific instructions for dissolving the tablets, as this can affect the medication's effectiveness.

How to store IMATINATE 400 CAPSULE 30'S?Arrow

  • Keep IMATINATE 400MG CAP 1X30 away from the reach of children and pets.
  • Store IMATINATE 400MG CAP 1X30 at room temperature.

Benefits of IMATINATE 400 CAPSULE 30'SArrow

  • IMATINATE 400 CAPSULE 30'S is a targeted therapy medication that belongs to a class of drugs known as protein-tyrosine kinase inhibitors. It works by specifically blocking the activity of an abnormal protein, often resulting from a chromosomal abnormality, that drives the uncontrolled growth of cancer cells. This targeted action helps to slow down or stop the proliferation of these cells.
  • By inhibiting this specific protein, IMATINATE 400 CAPSULE 30'S effectively disrupts the signaling pathways that promote cancer cell division and survival. This targeted approach minimizes damage to healthy cells, reducing the severity of side effects often associated with traditional chemotherapy.
  • The medication not only inhibits the multiplication of abnormal cancer cells but also induces apoptosis, or programmed cell death, in these cells. This dual action helps to reduce the overall cancer burden and prevent the disease from progressing. Regular monitoring and consultation with a healthcare professional are essential to ensure the safe and effective use of this medication.

How to use IMATINATE 400 CAPSULE 30'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with IMATINATE 400 CAPSULE 30'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to strictly adhere to your doctor's instructions regarding the use of this medication. Do not alter the dosage or frequency of administration without consulting your healthcare provider.
  • Administer IMATINATE 400 CAPSULE 30'S exactly as prescribed by your doctor. These tablets should be swallowed whole with a full glass of water. Avoid breaking, crushing, or chewing the tablets, as this can affect how the medication is absorbed and works in your body. Maintaining the integrity of the tablet ensures you receive the correct dose.
  • To minimize the risk of stomach upset or other gastrointestinal issues, it is recommended to take IMATINATE 400 CAPSULE 30'S with a meal. Food can help to buffer the medication and reduce potential irritation to the stomach lining. If you consistently experience stomach problems despite taking it with food, inform your doctor.
  • If you have difficulty swallowing the tablets whole, consult your doctor or pharmacist for alternative methods of administration. In some cases, the tablets may be dissolved in water as per your doctor's specific directions. However, do not attempt to dissolve the tablets without professional guidance, as this could affect their effectiveness.

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FAQs

How to use IMATINATE 400 CAPSULE 30'S?Arrow

IMATINATE 400 CAPSULE 30'S is administered orally, in the form of a tablet or capsule, and the dose depends on several factors, including the condition being treated, the weight of the patient, the particular regimen being used, and the overall health of the patient. It should be taken with food and a large glass of water to minimize gastrointestinal irritation.

Ever since I started using IMATINATE 400 CAPSULE 30'S, I have noticed rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?Arrow

This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness, or severe sunburn. When you are outdoors, wear protective clothing and use sunscreen with an SPF. Consult your doctor before taking necessary precautions.

Can IMATINATE 400 CAPSULE 30'S cause kidney damage?Arrow

Yes, when taken for a longer period the medicine may cause damage to your kidneys. Your doctors may recommend you take a routine blood tests to assess your kidney function.

When is the best time to take IMATINATE 400 CAPSULE 30'S?Arrow

Take the tablet as prescribed by your doctor. Take IMATINATE 400 CAPSULE 30'S at the same time every day. It is usually taken with a meal and a large glass of water to avoid stomach problems.

Does IMATINATE 400 CAPSULE 30'S affect memory?Arrow

Memory impairments have been only reported in limited studies. Consult your doctor immediately if you have any trouble in concentrating.

Does IMATINATE 400 CAPSULE 30'S interact with other drugs?Arrow

NULL interaction of IMATINATE 400 CAPSULE 30'S with other drungs

What precautions should I take while taking IMATINATE 400 CAPSULE 30'S?Arrow

You may become more sensitive to the sun while taking IMATINATE 400 CAPSULE 30'S. It is important to cover sun-exposed areas of skin and use sunscreen with a high sun protection factor after consulting with your doctor. The medicine should be administered cautiously in patients with kidney problems. This tablet may cause your body to retain water, inform your physician if you put on weight very quickly after the therapy. Your doctor will regularly do lab tests to check whether the medicine works. Do not breastfeed during the treatment with this medicine and for 15 days after your last dose.

What is IMATINATE 400 CAPSULE 30'S made of?Arrow

IMATINIB is molecule/combination used for making IMATINATE 400 CAPSULE 30'S.

What conditions is IMATINATE 400 CAPSULE 30'S prescribed for?Arrow

IMATINATE 400 CAPSULE 30'S is prescribed for Oncology.

Is IMATINATE 400 CAPSULE 30'S used in Oncology?Arrow

Yes, IMATINATE 400 CAPSULE 30'S is used in Oncology.

References

Book Icon

Imatinib 400mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk.

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Marketer / Manufacturer Details

KHANDELWAL LABORATORIES PRIVATE LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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