ARBITEL AM TABLET 15'S

How ARBITEL AM TABLET 15'S Works

• ARBITEL AM TABLET 15'S is a combination medication designed to manage hypertension (high blood pressure) effectively. It combines the actions of two active ingredients: Amlodipine and Telmisartan. Understanding how each component works is crucial to appreciating the overall therapeutic effect of ARBITEL AM.
• Telmisartan belongs to a class of drugs called angiotensin II receptor blockers (ARBs). Angiotensin II is a hormone that causes blood vessels to constrict, leading to increased blood pressure. Telmisartan works by blocking the effects of angiotensin II. Specifically, it binds to the angiotensin II receptors located in the smooth muscle of blood vessels and in the adrenal gland. By blocking these receptors, telmisartan prevents angiotensin II from constricting the blood vessels. This allows the blood vessels to relax and widen, which in turn lowers blood pressure. Additionally, telmisartan reduces the release of aldosterone, a hormone that causes the kidneys to retain sodium and water. By reducing aldosterone levels, telmisartan promotes the excretion of sodium and water, further contributing to lower blood pressure. The overall effect of telmisartan is a reduction in systemic vascular resistance, leading to a sustained decrease in blood pressure.
• Amlodipine, on the other hand, is a calcium channel blocker. Calcium plays a vital role in muscle contraction, including the muscles in the walls of blood vessels. Amlodipine works by blocking calcium from entering these muscle cells. This blockage reduces the contraction of the blood vessels, causing them to relax and widen. Specifically, amlodipine inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle cells. By reducing calcium influx, amlodipine causes vasodilation (widening of blood vessels), which lowers blood pressure. Amlodipine primarily affects the arteries, reducing the afterload on the heart. Afterload is the resistance the heart must overcome to pump blood into the arteries. By reducing afterload, amlodipine makes it easier for the heart to pump blood, reducing the workload on the heart and improving cardiac function.
• In summary, ARBITEL AM TABLET 15'S combines the blood pressure-lowering effects of telmisartan and amlodipine. Telmisartan blocks the effects of angiotensin II, preventing blood vessel constriction, while amlodipine blocks calcium channels, causing blood vessels to relax. Together, these mechanisms work synergistically to lower blood pressure more effectively than either drug alone. This combination helps to reduce the risk of cardiovascular events, such as heart attack and stroke, in patients with hypertension. Regular monitoring of blood pressure and adherence to the prescribed dosage are essential for optimal management of hypertension with ARBITEL AM.
• The synergistic effect of these two medications ensures a comprehensive approach to managing hypertension, addressing both the hormonal and muscular aspects of blood pressure regulation.

Common side effects of Arbitel AM Tablet may include headache, dizziness, lightheadedness, flushing (sense of warmth in the face, ears, neck, and trunk), ankle swelling, fatigue, palpitations, and nausea. Less common side effects can include orthostatic hypotension (low blood pressure when standing up), cough, diarrhea, constipation, dyspepsia (indigestion), muscle cramps, back pain, joint pain, and changes in heart rate. Rare but potentially serious side effects include allergic reactions (rash, itching, swelling), angioedema (swelling of the face, lips, tongue, or throat), and severe hypotension. Patients should consult their doctor if they experience any persistent or severe side effects.

• If you miss a dose of ARBITEL AM TABLET 15'S, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep ARBITEL AM TAB 1X15 away from the reach of children and pets.
• Store ARBITEL AM TAB 1X15 at room temperature.

• Take ARBITEL AM TABLET 15'S exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting your physician, as this could lead to uncontrolled blood pressure and potential health risks. It's typically taken once daily, with or without food, but consistency is key for optimal results.
• ARBITEL AM TABLET 15'S contains two medications: Amlodipine and Telmisartan. Amlodipine can sometimes cause swelling in the ankles and feet. If you experience this, try elevating your legs while sitting or lying down. If the swelling becomes severe or uncomfortable, inform your doctor.
• Monitor your blood pressure regularly while taking ARBITEL AM TABLET 15'S. Keep a log of your readings and share it with your doctor during your check-ups. This helps your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Aim for readings within the target range set by your healthcare provider.
• Avoid consuming grapefruit or grapefruit juice while taking ARBITEL AM TABLET 15'S, as it can interact with Amlodipine, potentially increasing the levels of the drug in your body and leading to increased side effects. Check all your juice products and foods before consumption.
• Be mindful of potential side effects, such as dizziness, lightheadedness, or headache. These are more likely to occur when you first start taking ARBITEL AM TABLET 15'S or when your dosage is increased. If you experience any of these, stand up slowly from a sitting or lying position to avoid falls. If side effects persist or worsen, contact your doctor immediately. It is important to also be cautious while driving or doing activities that require full concentration.