TELKAV AM TABLET 15'S

How TELKAV AM TABLET 15'S Works

• TELKAV AM TABLET 15'S is a combination medication designed to manage hypertension (high blood pressure) effectively. It combines the power of two active ingredients: Telmisartan and Amlodipine, each working through distinct mechanisms to lower blood pressure.
• Telmisartan belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). Angiotensin II is a naturally occurring hormone in the body that causes blood vessels to constrict, leading to increased blood pressure. Telmisartan works by blocking the action of angiotensin II. By preventing angiotensin II from binding to its receptors in blood vessel walls, Telmisartan allows the blood vessels to relax and widen. This vasodilation reduces the resistance against which the heart has to pump, thereby lowering blood pressure. Furthermore, Telmisartan helps to reduce the release of aldosterone, a hormone that causes the kidneys to retain sodium and water, further contributing to blood pressure reduction. The overall effect is a sustained and controlled lowering of blood pressure.
• Amlodipine, on the other hand, is a calcium channel blocker. Calcium plays a crucial role in muscle contraction, including the muscles in the walls of blood vessels. Amlodipine works by blocking calcium from entering these muscle cells. This blockage prevents the muscles from contracting, causing the blood vessels to relax and widen. By relaxing the blood vessels, Amlodipine decreases the resistance to blood flow, which in turn lowers blood pressure. Amlodipine primarily affects the arteries and arterioles, the smaller blood vessels, and its effects are more pronounced in these vessels. This targeted action helps to reduce the workload on the heart and improve blood flow throughout the body.
• The combination of Telmisartan and Amlodipine in TELKAV AM TABLET 15'S provides a synergistic effect, meaning that the two drugs work together to lower blood pressure more effectively than either drug would alone. Telmisartan addresses the hormonal component of blood pressure regulation by blocking angiotensin II, while Amlodipine tackles the calcium-dependent muscle contraction in blood vessel walls. This dual-action approach allows for comprehensive blood pressure control, reducing the risk of cardiovascular complications associated with hypertension, such as heart attack, stroke, and kidney disease. The combined action provides smoother and more consistent blood pressure control throughout the day, which is essential for managing hypertension effectively. Regular monitoring of blood pressure and adherence to the prescribed dosage are important for optimal therapeutic outcomes.
• In summary, TELKAV AM TABLET 15'S effectively lowers blood pressure by combining Telmisartan's action of blocking angiotensin II receptors, leading to vasodilation and reduced aldosterone release, with Amlodipine's action of blocking calcium channels in blood vessel walls, causing relaxation and widening of the vessels. This dual mechanism provides comprehensive and sustained blood pressure control, reducing the risk of cardiovascular events associated with hypertension.

Common side effects of Telkav AM Tablet may include headache, dizziness, fatigue, sleepiness, nausea, flushing (sense of warmth in the face, ears, neck and trunk), palpitations, ankle swelling, and abdominal pain. Less common but potentially serious side effects include: hypotension (low blood pressure), increased heart rate, muscle cramps or weakness, allergic reactions (rash, itching, swelling), and changes in liver function tests. Rare side effects may involve: mood changes, tremors, difficulty breathing, severe skin reactions, and chest pain. This is not an exhaustive list. If you experience any unusual symptoms while taking Telkav AM Tablet, consult your doctor immediately.

• If you miss a dose of TELKAV AM TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep TELKAV AM TAB 1X15 away from the reach of children and pets.
• Store TELKAV AM TAB 1X15 at room temperature.

• TELKAV AM TABLET 15'S does not have any known significant interactions with food. It can be taken with or without food. However, it is advisable to take it at the same time each day to maintain consistent blood levels of the medication.
• Avoid grapefruit and grapefruit juice while taking this medicine, as it can increase the levels of amlodipine in your blood, potentially leading to increased side effects.