BENDAMAX 100 INJECTION
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BENDAMAX 100 INJECTION
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BENDAMAX 100 INJECTION

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BENDAMAX 100 INJECTION

By GLS PHARMA LIMITED

MRP

₹

2267

₹1465

35.38 % OFF

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Product DetailsArrow

About BENDAMAX 100 INJECTION

  • BENDAMAX 100 INJECTION is an antineoplastic drug belonging to the class of alkylating agents, containing the active ingredient Bendamustine. It is used to prevent and treat chronic lymphocytic leukaemia (cancer of blood and bone marrow), non-Hodgkin’s lymphomas (cancer that forms in the lymph system, part of the immune system), and multiple myelomas (cancer of plasma cells, a type of white blood cell). This medication works by slowing or stopping the growth of cancer cells in the body. It disrupts the DNA and RNA of cancer cells, ultimately leading to their death.
  • The common side effects that are likely to occur with this medicine are headache, insomnia, fatigue, loss of appetite, and rashes. Some serious side effects also include bone marrow suppression, tumor lysis syndrome, and Hepatotoxicity. Inform your healthcare provider if these side effects concern you or persist for longer than usual. It is often combined with rituximab, an immunotherapy drug, to treat various subtypes of non-Hodgkin's lymphoma, including follicular lymphoma, and mantle cell lymphoma. There may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine. Consult your doctor immediately for more advice. Regular monitoring by your healthcare provider is crucial while on this medication to manage and mitigate potential side effects.
  • Treatment should not be started if your white blood cells (leukocytes) have fallen to counts below determined levels. Your doctor will determine these values at regular intervals. This medicine should not be used if you are allergic to this drug. If you are a man wanting to father a child, you should discuss the treatment with your physician, as taking this injection may reduce sperm production in men. This drug is typically given as an intravenous infusion over a period of 30-60 minutes. It is usually administered once every three to four weeks. Tell your physician about all the medications you have been taking recently, including herbal medicines and supplements, before taking BENDAMAX 100 INJECTION. It's essential to maintain open communication with your doctor regarding your medical history and any concerns you may have during the treatment. This ensures the safe and effective use of the medication.

Uses of BENDAMAX 100 INJECTION

  • Chronic lymphocytic leukemia, a type of cancer that affects the blood and bone marrow, characterized by the gradual increase of abnormal lymphocytes.
  • Non-Hodgkin's lymphomas, a diverse group of blood cancers that develop from lymphocytes, which are a type of white blood cell, and can occur at any age.
  • Multiple myeloma, a cancer that forms in plasma cells, a type of white blood cell responsible for producing antibodies, leading to weakened bones and immune system problems.

Side Effects of BENDAMAX 100 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. BENDAMAX 100 INJECTION can cause both serious and common side effects.

  • Severe allergic reactions
  • Bone marrow suppression
  • Abnormal liver function
  • Tumor lysis syndrome
  • Infection, fever
  • Low blood cell count
  • Headache, dizziness
  • Nausea, vomiting
  • Increased blood level of creatinine and urea (chemical waste products)
  • Mucosal inflammation, sore mouth
  • Insomnia, fatigue
  • Hair loss, itching, rash
  • Diarrhea, constipation
  • Missed periods
  • Dehydration, loss of appetite
  • Low or high blood pressure

Safety Advice for BENDAMAX 100 INJECTIONArrow

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Pregnancy

UNSAFE

BENDAMAX 100 INJECTION is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of BENDAMAX 100 INJECTIONArrow

  • BENDAMAX 100 INJECTION will be administered by a healthcare professional in a hospital or clinical setting, ensuring proper monitoring and management of any potential side effects. This medication is delivered intravenously, meaning it's injected directly into a vein, typically in your arm or hand. It is crucial that you do not attempt to self-administer this medicine.
  • Your doctor will determine the appropriate dosage of BENDAMAX 100 INJECTION based on several factors, including your specific medical condition, overall health, and any other medications you may be taking. This personalized approach ensures the medication is both safe and effective for you.
  • BENDAMAX 100 INJECTION is commonly administered approximately 30 minutes before chemotherapy to help mitigate potential side effects of the anti-cancer treatment. It may also be given right before anesthesia for surgery. This timing is carefully planned to optimize its therapeutic benefits.
  • During the infusion process, you will be closely monitored by medical staff to detect any adverse reactions or side effects. This vigilant observation allows for immediate intervention if needed, ensuring your comfort and safety. The infusion typically takes several hours, and the complete treatment plan may involve multiple infusions scheduled over several weeks, depending on your individual needs and treatment goals.

How to store BENDAMAX 100 INJECTION?Arrow

  • Keep BENDAMAX 100MG INJ away from the reach of children and pets.
  • Store BENDAMAX 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of BENDAMAX 100 INJECTIONArrow

  • BENDAMAX 100 INJECTION is a chemotherapy medication classified as an alkylating agent. This means it fights cancer by directly damaging the DNA within cancer cells. This damage is crucial because DNA is the blueprint for cell growth and division. By disrupting the DNA, BENDAMAX 100 INJECTION interferes with the cell's ability to replicate, ultimately leading to its death.
  • The mechanism of action involves the formation of strong, irreversible links (covalent bonds) with the DNA strands. These bonds prevent the DNA from unwinding and replicating properly. Furthermore, BENDAMAX 100 INJECTION can hinder the function of DNA repair enzymes, making it difficult for the cancer cells to fix the damage caused by the drug.
  • By interfering with DNA replication and repair, BENDAMAX 100 INJECTION effectively halts the cell cycle, the series of steps a cell goes through to divide. Cancer cells, which are characterized by uncontrolled growth and division, are particularly vulnerable to this disruption. The cytotoxic effect of BENDAMAX 100 INJECTION selectively targets these rapidly dividing cancer cells, helping to reduce the tumor size and control the spread of the disease.
  • In essence, BENDAMAX 100 INJECTION is a powerful tool in cancer treatment, acting as a cytotoxic agent to eliminate cancer cells by disrupting their DNA and inhibiting their cell cycle progression. This targeted approach helps to minimize the impact on healthy cells, although some side effects are still possible.

How to use BENDAMAX 100 INJECTIONArrow

  • BENDAMAX 100 INJECTION will be administered to you by a trained healthcare professional in a hospital or clinical setting. This medication is given intravenously, meaning it's injected directly into a vein, usually in your arm or hand. It is crucial that you do not attempt to self-administer this medicine under any circumstances.
  • The precise dosage of BENDAMAX 100 INJECTION will be determined by your doctor, taking into account your specific medical condition, overall health, and other relevant factors. Your doctor will tailor the dosage to achieve the best possible outcome for you.
  • Typically, BENDAMAX 100 INJECTION is administered approximately 30 minutes before you receive your anti-cancer medicine (chemotherapy) or immediately prior to anaesthesia for a surgical procedure. This timing is carefully chosen to optimize the medication's effects.
  • Throughout the infusion process, you will be closely monitored by healthcare staff for any potential side effects or adverse reactions to the medication. Your comfort and safety are of utmost importance.
  • The infusion process can take several hours to complete. Depending on your treatment plan, you may need to receive multiple infusions over a period of several weeks. Your doctor will determine the appropriate schedule for your infusions based on your individual needs and response to the treatment.

FAQs

What is BENDAMAX 100 INJECTION used for?Arrow

BENDAMAX 100 INJECTION is a chemotherapy drug used to treat various types of cancers, including non-Hodgkin's lymphoma, chronic lymphocytic leukaemia, and multiple myeloma.

How will I receive BENDAMAX 100 INJECTION?Arrow

BENDAMAX 100 INJECTION is administered into a vein as a short-term infusion over 30 – 60 minutes.

How does BENDAMAX 100 INJECTION work to treat cancer?Arrow

BENDAMAX 100 INJECTION works by damaging the DNA in cancer cells, preventing them from multiplying and spreading.

Can BENDAMAX 100 INJECTION be used in combination with other drugs?Arrow

Yes, BENDAMAX 100 INJECTION is often used in combination with other chemotherapy drugs to improve treatment outcomes.

Whether BENDAMAX 100 INJECTION is safe to use during pregnancy?Arrow

BENDAMAX 100 INJECTION is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.

Who should not take BENDAMAX 100 INJECTION?Arrow

BENDAMAX 100 INJECTION should not be taken by individuals who are allergic to it or its ingredients.

Does BENDAMAX 100 INJECTION interact with other drugs?Arrow

There are no known negative interactions of BENDAMAX 100 INJECTION with other drugs.

What precautions should I take while using BENDAMAX 100 INJECTION?Arrow

BENDAMAX 100 INJECTION can cause harm to a developing fetus or nursing baby, so it is important to discuss contraception options and the need to avoid breastfeeding during treatment. This drug causes fatigue, so encourage the patient to take enough rest and self-care during treatment. This medicine increases the risk of bleeding and bruising, so it is important to be careful when using sharp objects or participating in activities that may result in injury.

What molecule/combination is used for making BENDAMAX 100 INJECTION?Arrow

Bendamustine is the molecule/combination used for making BENDAMAX 100 INJECTION.

For which ailments/diseases/conditions is BENDAMAX 100 INJECTION prescribed?Arrow

BENDAMAX 100 INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

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Zentiva Pharma UK Limited, Electronic medicines compendium (emc)

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Teva Pharmaceuticals USA, Inc, US Food and Drug Administration

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Bendamustine 25mg how to store Bendamustine Powder

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WHO GMP certified generic medicines at affordable prices are available

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Reviewed on 17-07-2023

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Marketer / Manufacturer Details

GLS PHARMA LIMITED

Country of Origin -

India

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BENDAMAX 100 INJECTION

BENDAMAX 100 INJECTION

MRP

₹

2267

₹1465

35.38 % OFF

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