ENDAMUST 100MG INJECTION
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ENDAMUST 100MG INJECTION
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ENDAMUST 100MG INJECTION

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ENDAMUST 100MG INJECTION

By AUREATE HEALTHCARE PRIVATE LIMITED

MRP

6900

₹1923

72.13 % OFF

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Product DetailsArrow

About ENDAMUST 100MG INJECTION

  • ENDAMUST 100MG INJECTION is an antineoplastic drug that belongs to the class of alkylating agents and contains the active ingredient Bendamustine. It plays a crucial role in preventing and treating several types of cancers, including chronic lymphocytic leukaemia (a cancer affecting the blood and bone marrow), non-Hodgkin’s lymphomas (cancers originating in the lymph system, a vital part of the immune system), and multiple myelomas (a cancer of plasma cells, a specific type of white blood cell).
  • Common side effects associated with this medication include headache, insomnia, fatigue, loss of appetite, and skin rashes. More serious side effects can also occur, such as bone marrow suppression (a decrease in the production of blood cells), tumor lysis syndrome (a condition caused by the rapid breakdown of cancer cells), and hepatotoxicity (liver damage). It's essential to inform your healthcare provider if these side effects become bothersome or persist for an extended period. This injection is often used in combination with rituximab, an immunotherapy drug, to enhance its effectiveness in treating various subtypes of non-Hodgkin's lymphoma, like follicular lymphoma and mantle cell lymphoma. Patients should be aware of a potentially increased risk of certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine, and consulting a doctor immediately is recommended for personalized advice.
  • Treatment with ENDAMUST 100MG INJECTION should not be initiated if your white blood cell count (leukocytes) falls below a certain level, as determined by your doctor through regular monitoring. It is contraindicated if you have a known allergy to Bendamustine. Men who are considering fathering a child should discuss the potential impact of this medication with their physician, as it may reduce sperm production. The drug is typically administered as an intravenous infusion over 30 to 60 minutes, usually once every three to four weeks. Before starting ENDAMUST 100MG INJECTION, inform your physician about all medications you are currently taking, including herbal remedies and supplements, to avoid any potential drug interactions. Regular monitoring and open communication with your healthcare team are key to ensuring safe and effective treatment.
  • It's important to maintain good hydration during the treatment period and to report any unusual symptoms to your healthcare provider promptly. Dosage adjustments may be necessary based on individual response and tolerance to the medication. Long-term follow-up is recommended to monitor for any delayed side effects or complications. The information provided here is for general knowledge and does not substitute professional medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment of any medical condition.

Uses of ENDAMUST 100MG INJECTION

  • Chronic lymphocytic leukemia, a type of cancer affecting the blood and bone marrow, characterized by the gradual increase of abnormal lymphocytes.
  • Non-Hodgkin's lymphomas, a diverse group of blood cancers that develop from lymphocytes, differing from Hodgkin's lymphoma in specific cell characteristics and disease progression.
  • Multiple myeloma, a cancer of plasma cells in the bone marrow that leads to the overproduction of abnormal antibodies and can cause bone damage, kidney problems, and other complications.

Side Effects of ENDAMUST 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Serious side effects include severe allergic reactions, bone marrow suppression, abnormal liver function, and tumor lysis syndrome. Common side effects include infection, fever, low blood cell count, headache, dizziness, nausea, vomiting, increased blood levels of creatinine and urea (chemical waste products), mucosal inflammation, sore mouth, insomnia, fatigue, hair loss, itching, rash, diarrhea, constipation, missed periods, dehydration, loss of appetite, and low or high blood pressure.

  • Severe allergic reactions
  • Bone marrow suppression
  • Abnormal liver function
  • Tumor lysis syndrome
  • Infection, fever
  • Low blood cell count
  • Headache, dizziness
  • Nausea, vomiting
  • Increased blood level of creatinine and urea (chemical waste products)
  • Mucosal inflammation, sore mouth
  • Insomnia, fatigue
  • Hair loss, itching, rash
  • Diarrhea, constipation
  • Missed periods
  • Dehydration, loss of appetite
  • Low or high blood pressure

Safety Advice for ENDAMUST 100MG INJECTIONArrow

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Pregnancy

UNSAFE

ENDAMUST 100MG INJECTION is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of ENDAMUST 100MG INJECTIONArrow

  • ENDAMUST 100MG INJECTION will be administered by a healthcare professional in a hospital setting to ensure proper monitoring and immediate management of any potential side effects. This medication is given intravenously, meaning it will be injected directly into a vein in your arm or hand. It is crucial that you do not attempt to self-administer this medicine.
  • Your doctor will determine the precise dose of ENDAMUST 100MG INJECTION based on several factors, including your specific disease condition, overall health, and other medications you may be taking. This personalized approach ensures the medication is tailored to your individual needs.
  • Typically, ENDAMUST 100MG INJECTION is administered approximately 30 minutes before you receive your anti-cancer medicine (chemotherapy) or immediately before anesthesia for surgery. This timing is important for maximizing the medication's effectiveness and minimizing potential complications.
  • During the infusion process, you will be closely monitored by healthcare professionals for any adverse reactions or side effects. The infusion can take several hours to complete, and depending on your treatment plan, you may need to receive multiple infusions over several weeks. This extended treatment period allows for sustained therapeutic benefits.
  • It is important to communicate any concerns or discomfort you experience during the infusion to your healthcare provider immediately. They are equipped to manage any issues that may arise and ensure your safety and comfort throughout the treatment.

How to store ENDAMUST 100MG INJECTION?Arrow

  • Keep ENDAMUST 100MG INJ away from the reach of children and pets.
  • Store ENDAMUST 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ENDAMUST 100MG INJECTIONArrow

  • ENDAMUST 100MG INJECTION is a powerful chemotherapy medication that belongs to the class of alkylating agents. Its primary mechanism of action involves targeting the DNA of cancer cells. By forming covalent bonds with DNA, ENDAMUST 100MG INJECTION disrupts the normal DNA structure and function, which is essential for cell survival and replication.
  • This disruption leads to a cascade of effects within the cancer cells. Firstly, it inhibits the activity of DNA repair enzymes, preventing the cells from repairing the damage caused by the drug. Secondly, it blocks the progression of the cell cycle, halting the cells from dividing and multiplying. Ultimately, these combined effects lead to cancer cell death.
  • ENDAMUST 100MG INJECTION is a cytotoxic drug, meaning it is toxic to cells, particularly cancer cells. It works by directly interfering with the DNA and cell cycle processes that are crucial for cancer cell growth and spread. This makes it an effective treatment option for various types of cancer, as it can selectively target and eliminate cancerous cells while minimizing damage to healthy cells.

How to use ENDAMUST 100MG INJECTIONArrow

  • ENDAMUST 100MG INJECTION will be administered to you by a healthcare professional in a hospital or clinic setting. It is not intended for self-administration. The medication will be given intravenously, directly into a vein in your arm or hand.
  • The precise dosage and frequency of ENDAMUST 100MG INJECTION will be determined by your doctor, taking into account your specific medical condition, overall health, and other relevant factors. It's crucial to adhere to the prescribed dosage for optimal results.
  • Typically, this injection is administered approximately 30 minutes before you receive your anti-cancer medicine (chemotherapy) or immediately before anaesthesia for a surgical procedure. This timing is crucial for the drug's effectiveness.
  • Throughout the infusion process, you will be carefully monitored by medical personnel for any potential side effects or adverse reactions to ENDAMUST 100MG INJECTION. This ensures your safety and allows for immediate intervention if needed.
  • The infusion process can take several hours to complete, and you might need to receive multiple infusions over a period of several weeks, as determined by your healthcare provider. Regular follow-up appointments are important to assess your progress and manage any potential side effects.

FAQs

What is ENDAMUST 100MG INJECTION used for?Arrow

ENDAMUST 100MG INJECTION is a chemotherapy drug used to treat various types of cancers, including non-Hodgkin's lymphoma, chronic lymphocytic leukaemia, and multiple myeloma.

How will I receive ENDAMUST 100MG INJECTION?Arrow

ENDAMUST 100MG INJECTION is administered into a vein as a short-term infusion over 30 – 60 minutes.

How does ENDAMUST 100MG INJECTION work to treat cancer?Arrow

ENDAMUST 100MG INJECTION works by damaging the DNA in cancer cells, preventing them from multiplying and spreading.

Can ENDAMUST 100MG INJECTION be used in combination with other drugs?Arrow

Yes, ENDAMUST 100MG INJECTION is often used in combination with other chemotherapy drugs to improve treatment outcomes.

Whether ENDAMUST 100MG INJECTION is safe to use during pregnancy?Arrow

ENDAMUST 100MG INJECTION is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.

Who should not take ENDAMUST 100MG INJECTION?Arrow

ENDAMUST 100MG INJECTION should not be taken by individuals who are allergic to it or its ingredients.

Does ENDAMUST 100MG INJECTION interact with other drugs?Arrow

There are no known significant interactions of ENDAMUST 100MG INJECTION with other drugs.

What precautions should I take while taking ENDAMUST 100MG INJECTION?Arrow

ENDAMUST 100MG INJECTION can cause harm to a developing fetus or nursing baby, so it is important to discuss contraception options and the need to avoid breastfeeding during treatment. This drug causes fatigue, so encourage the patient to take enough rest and self-care during treatment. This injection increases the risk of bleeding and bruising, so it is important to be careful when using sharp objects or participating in activities that may result in injury.

What molecule/combination is used for making ENDAMUST 100MG INJECTION?Arrow

BENDAMUSTINE is molecule/combination used for making ENDAMUST 100MG INJECTION.

For what type of cancer is ENDAMUST 100MG INJECTION prescribed?Arrow

ENDAMUST 100MG INJECTION is prescribed for Oncology.

References

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Zentiva Pharma UK Limited, Electronic medicines compendium (emc)

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Teva Pharmaceuticals USA, Inc, US Food and Drug Administration

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Bendamustine 25mg how to store Bendamustine Powder

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Marketer / Manufacturer Details

AUREATE HEALTHCARE PRIVATE LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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