GENMUS 100 INJECTION
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GENMUS 100 INJECTION
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GENMUS 100 INJECTION

By BDR PHARMACEUTICALS INTERNATIONALS PVT LTD

MRP

2214.52

₹1364

38.41 % OFF

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Product DetailsArrow

About GENMUS 100 INJECTION

  • GENMUS 100 INJECTION is an antineoplastic drug belonging to the class of alkylating agents, containing the active ingredient Bendamustine. It is used to prevent and treat chronic lymphocytic leukaemia (cancer of blood and bone marrow), non-Hodgkin’s lymphomas (cancer that forms in the lymph system, part of the immune system), and multiple myelomas (cancer of plasma cells, a type of white blood cell).
  • The common side effects that are likely to occur with this medicine are headache, insomnia, fatigue, loss of appetite, and rashes. Some serious side effects also include bone marrow suppression, tumor lysis syndrome, and Hepatotoxicity. It is crucial to inform your healthcare provider if these side effects concern you or persist for longer than usual. This medication is often combined with rituximab, an immunotherapy drug, to treat various subtypes of non-Hodgkin's lymphoma, including follicular lymphoma and mantle cell lymphoma. There may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine. Consult your doctor immediately for more advice and guidance.
  • Before starting treatment with GENMUS 100 INJECTION, it is important to ensure that your white blood cell (leukocyte) counts are above a determined level. Your doctor will monitor these values at regular intervals to ensure your safety. This medicine should not be used if you have a known allergy to Bendamustine or any of the other ingredients in the injection. If you are a man planning to father a child, it is essential to discuss the potential impact of this treatment with your physician, as GENMUS 100 INJECTION may reduce sperm production in men. The drug is typically administered as an intravenous infusion over 30-60 minutes, usually once every three to four weeks. Make sure to inform your physician about all the medications you are currently taking, including herbal medicines and supplements, to avoid any potential drug interactions.
  • Furthermore, patients with pre-existing liver or kidney conditions should exercise caution and inform their healthcare provider before initiating GENMUS 100 INJECTION treatment, as dosage adjustments may be necessary. Regular monitoring of liver and kidney function is advisable during the course of treatment. It is also important to maintain adequate hydration while receiving this medication, as it can help to prevent kidney problems. Patients should promptly report any signs of infection, such as fever, cough, or sore throat, to their doctor.

Uses of GENMUS 100 INJECTION

  • Chronic lymphocytic leukemia, a type of cancer that affects the blood and bone marrow, characterized by a gradual increase in abnormal lymphocytes.
  • Non-Hodgkin’s lymphomas, which encompass a diverse group of blood cancers affecting lymphocytes, potentially originating in lymph nodes throughout the body.
  • Multiple myeloma, a cancer of plasma cells that are found in the bone marrow and produce abnormal antibodies, leading to various complications.

Side Effects of GENMUS 100 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, although not everyone experiences them. GENMUS 100 INJECTION can cause both serious and common side effects.

  • Severe allergic reactions
  • Bone marrow suppression
  • Abnormal liver function
  • Tumor lysis syndrome
  • Infection, fever
  • Low blood cell count
  • Headache, dizziness
  • Nausea, vomiting
  • Increased blood level of creatinine and urea (chemical waste products)
  • Mucosal inflammation, sore mouth
  • Insomnia, fatigue
  • Hair loss, itching, rash
  • Diarrhea, constipation
  • Missed periods
  • Dehydration, loss of appetite
  • Low or high blood pressure

Safety Advice for GENMUS 100 INJECTIONArrow

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Pregnancy

UNSAFE

GENMUS 100 INJECTION is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of GENMUS 100 INJECTIONArrow

  • GENMUS 100 INJECTION will be given to you by a trained healthcare professional while you are in the hospital. It is administered intravenously, meaning it's injected directly into a vein, usually in your arm or hand. It is crucial that you do not attempt to administer this medication to yourself.
  • Your doctor will determine the precise dosage based on your specific medical condition, your overall health, and other relevant factors. Typically, this injection is given approximately 30 minutes prior to your chemotherapy treatment or immediately before you receive anesthesia for a surgical procedure. This timing allows the medication to take effect and provide the necessary protection.
  • During the infusion process, the healthcare team will closely monitor you for any potential side effects or adverse reactions to the medication. This vigilance ensures your safety and allows for immediate intervention if needed. The infusion process can take several hours, and you may require multiple infusions spaced out over several weeks, depending on your treatment plan and the severity of your condition. It's important to adhere to the prescribed schedule for optimal results.

How to store GENMUS 100 INJECTION?Arrow

  • Keep GENMUS 100MG INJ away from the reach of children and pets.
  • Store GENMUS 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of GENMUS 100 INJECTIONArrow

  • GENMUS 100 INJECTION is a powerful chemotherapy medication that belongs to a class of drugs known as alkylating agents. Its primary mechanism of action involves targeting the DNA of cancer cells. The drug works by forming strong, irreversible bonds with the DNA strands, which causes significant damage. This damage disrupts the normal functioning of the cell and interferes with its ability to replicate and divide.
  • By creating these covalent bonds, GENMUS 100 INJECTION effectively inhibits the DNA repair enzymes that cancer cells rely on to fix any errors or damage to their genetic material. This further exacerbates the damage and prevents the cancer cells from repairing themselves.
  • Moreover, GENMUS 100 INJECTION also blocks the cell cycle progression. The cell cycle is a tightly regulated process that controls the growth and division of cells. By interfering with this cycle, GENMUS 100 INJECTION prevents cancer cells from multiplying uncontrollably. Ultimately, the combined effect of DNA damage, inhibition of DNA repair, and cell cycle arrest leads to the death of cancer cells. This cytotoxic effect makes GENMUS 100 INJECTION a valuable tool in the treatment of various types of cancer.

How to use GENMUS 100 INJECTIONArrow

  • GENMUS 100 INJECTION will be administered to you by a healthcare professional in a hospital or clinic setting. It is crucial that you do not attempt to self-administer this medication.
  • The injection will be given intravenously, which means it will be delivered directly into a vein in your arm or hand through a needle. The specific dosage and frequency of GENMUS 100 INJECTION will be determined by your doctor, taking into account your individual disease condition, overall health, and response to treatment.
  • Typically, this injection is administered approximately 30 minutes prior to receiving anti-cancer medicine (chemotherapy) or immediately before the administration of anesthesia for a surgical procedure. The timing is carefully coordinated to maximize the effectiveness of the medication.
  • During the infusion process, you will be closely monitored by healthcare professionals for any potential side effects or adverse reactions to the medication. This allows for immediate intervention if any issues arise.
  • The infusion process usually takes several hours to complete, and you may require multiple infusions spread out over the course of several weeks, depending on your treatment plan. Adhering to the prescribed schedule is essential for optimal results.

FAQs

What is GENMUS 100 INJECTION used for?Arrow

GENMUS 100 INJECTION is a chemotherapy drug used to treat various types of cancers, including non-Hodgkin's lymphoma, chronic lymphocytic leukaemia, and multiple myeloma.

How will I receive GENMUS 100 INJECTION?Arrow

GENMUS 100 INJECTION is administered into a vein as a short-term infusion over 30 – 60 minutes.

How does GENMUS 100 INJECTION work to treat cancer?Arrow

GENMUS 100 INJECTION works by damaging the DNA in cancer cells, preventing them from multiplying and spreading.

Can GENMUS 100 INJECTION be used in combination with other drugs?Arrow

Yes, GENMUS 100 INJECTION is often used in combination with other chemotherapy drugs to improve treatment outcomes.

Whether GENMUS 100 INJECTION is safe to use during pregnancy?Arrow

GENMUS 100 INJECTION is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.

Who should not take GENMUS 100 INJECTION?Arrow

GENMUS 100 INJECTION should not be taken by individuals who are allergic to it or its ingredients.

Does GENMUS 100 INJECTION interact with other drugs?Arrow

There are no known significant interactions of GENMUS 100 INJECTION with other drugs.

What advice should I follow while taking GENMUS 100 INJECTION?Arrow

GENMUS 100 INJECTION can cause harm to a developing fetus or nursing baby, so it is important to discuss contraception options and the need to avoid breastfeeding during treatment. This drug causes fatigue, so encourage the patient to take enough rest and self-care during treatment. This injection increases the risk of bleeding and bruising, so it is important to be careful when using sharp objects or participating in activities that may result in injury.

What is GENMUS 100 INJECTION made of?Arrow

GENMUS 100 INJECTION is made from a molecule/combination called Bendamustine.

For what ailments/diseases/conditions is GENMUS 100 INJECTION prescribed?Arrow

GENMUS 100 INJECTION is primarily prescribed for ailments related to Oncology (Cancer).

References

Book Icon

Zentiva Pharma UK Limited, Electronic medicines compendium (emc)

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Teva Pharmaceuticals USA, Inc, US Food and Drug Administration

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Bendamustine 25mg how to store Bendamustine Powder

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Nice experience, always!

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(5/5)

Well satisfying products. Generic medicines are way cheaper and of very good quality. Staff is well behaved and knowledgeable.

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Reviewed on 08-09-2023

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(5/5)


Marketer / Manufacturer Details

BDR PHARMACEUTICALS INTERNATIONALS PVT LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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