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DAPAGLIGEN V 10/100MG SR TABLET 10'S

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DAPAGLIGEN V 10/100MG SR TABLET 10'S

By TABLETS INDIA LIMITED

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700

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About DAPAGLIGEN V 10/100MG SR TABLET 10'S

  • Dapagliflozin and Vildagliptin combination, sold under the brand name DAPAGLIGEN V 10/100MG SR TABLET 10'S, is a dual-action medication designed to manage type 2 diabetes effectively. This medication combines two powerful active ingredients: Dapagliflozin and Vildagliptin, each working through different mechanisms to lower blood sugar levels and improve glycemic control.
  • Dapagliflozin belongs to a class of drugs known as Sodium-Glucose Co-transporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine. This process not only lowers blood sugar levels but also helps in weight management and may offer cardiovascular benefits. Clinical studies have shown that Dapagliflozin can reduce the risk of heart failure and cardiovascular death in patients with type 2 diabetes and established cardiovascular disease.
  • Vildagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It enhances the levels of incretin hormones in the body. Incretins are naturally occurring hormones that stimulate the release of insulin after a meal and reduce the secretion of glucagon, a hormone that raises blood sugar levels. By inhibiting the DPP-4 enzyme, Vildagliptin prolongs the action of incretins, resulting in improved insulin secretion and reduced glucagon levels, thereby lowering blood sugar.
  • The combination of Dapagliflozin and Vildagliptin in DAPAGLIGEN V 10/100MG SR TABLET 10'S offers a complementary approach to managing type 2 diabetes. While Dapagliflozin reduces glucose reabsorption in the kidneys, Vildagliptin enhances insulin secretion and reduces glucagon levels. This dual action helps to achieve better glycemic control compared to using either medication alone. The sustained-release (SR) formulation ensures a gradual release of the medication, providing a consistent effect throughout the day.
  • DAPAGLIGEN V 10/100MG SR TABLET 10'S is typically prescribed as an adjunct to diet and exercise in adults with type 2 diabetes. It is important to take this medication as directed by your healthcare provider, usually once daily. Regular monitoring of blood sugar levels and kidney function is recommended while taking this medication. Common side effects may include urinary tract infections, genital infections, and hypoglycemia (low blood sugar), especially when used with other diabetes medications like insulin or sulfonylureas. Consult your doctor if you experience any persistent or bothersome side effects.

Uses of DAPAGLIGEN V 10/100MG SR TABLET 10'S

  • Treatment of Type 2 Diabetes Mellitus
  • Lowering high blood sugar levels
  • Reducing cardiovascular risk (especially in patients with heart failure)
  • Slowing the progression of kidney disease (in patients with diabetes)
  • Aiding in weight management (under doctor's guidance)

How DAPAGLIGEN V 10/100MG SR TABLET 10'S Works

  • Dapagliflozin and Vildagliptin, the active ingredients in DAPAGLIGEN V 10/100MG SR TABLET 10'S, work through complementary mechanisms to effectively manage blood sugar levels in individuals with type 2 diabetes. Dapagliflozin belongs to a class of medications called sodium-glucose cotransporter 2 (SGLT2) inhibitors. These inhibitors work primarily in the kidneys. The kidneys filter glucose from the blood, and SGLT2 is responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin blocks the action of SGLT2, preventing the reabsorption of glucose. This leads to excess glucose being excreted in the urine, effectively lowering blood sugar levels. This process is independent of insulin, making it effective even in individuals with insulin resistance.
  • Vildagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that breaks down incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These incretin hormones play a crucial role in regulating blood sugar by stimulating insulin release from the pancreas and suppressing glucagon secretion from the liver, both of which help lower blood sugar levels, particularly after meals. Vildagliptin inhibits DPP-4, which increases the levels of active incretin hormones in the body. This enhances insulin secretion in response to elevated blood glucose and reduces glucagon secretion, resulting in improved blood sugar control. The 'SR' in the name signifies Sustained Release, meaning it releases the drug slowly, maintaining consistent blood levels.
  • By combining these two medications, DAPAGLIGEN V 10/100MG SR TABLET 10'S provides a dual-action approach to managing type 2 diabetes. Dapagliflozin reduces glucose reabsorption in the kidneys, while Vildagliptin enhances the effects of incretin hormones, leading to improved insulin secretion and reduced glucagon secretion. This synergistic action can result in better blood sugar control compared to either medication used alone. It’s important to remember that DAPAGLIGEN V 10/100MG SR TABLET 10'S is most effective when used in conjunction with a healthy diet and regular exercise. Following your doctor's instructions regarding dosage and lifestyle modifications is crucial for achieving optimal blood sugar management and overall health.

Side Effects of DAPAGLIGEN V 10/100MG SR TABLET 10'SArrow

The following side effects may occur while taking DAPAGLIFLOZIN V 10/100MG SR TABLET: **Common:** * Genital infections (both male and female) * Urinary tract infections (UTIs) * Increased urination * Thirst * Constipation * Nausea * Upper respiratory tract infections * Headache * Back pain * Dizziness * Changes in cholesterol levels **Uncommon:** * Dehydration * Yeast infection of the penis or vagina * Kidney problems * Hypoglycemia (low blood sugar), especially when taken with other diabetes medications like insulin or sulfonylureas * Weight loss * Increased creatinine levels in the blood * Dysuria (painful urination) **Rare:** * Diabetic ketoacidosis (DKA) - a serious condition with high levels of ketones in the blood or urine * Fournier's gangrene (necrotizing fasciitis of the perineum) - a rare but serious bacterial infection that affects the tissue under the skin around the genitals and perineum * Urosepsis (a life-threatening complication of a UTI) **If you experience any of these side effects or any other unusual symptoms, consult your doctor immediately.**

Safety Advice for DAPAGLIGEN V 10/100MG SR TABLET 10'SArrow

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Dosage of DAPAGLIGEN V 10/100MG SR TABLET 10'SArrow

  • The recommended dosage of 'DAPAGLIGEN V 10/100MG SR TABLET 10'S' is typically one tablet taken orally once daily. It is crucial to adhere to your physician's prescribed dosage and timing for optimal results. The tablet should be swallowed whole with a glass of water and can be taken with or without food. However, consistency in taking the medication, either always with food or always without, is advisable for better absorption and glycemic control.
  • The specific dosage may vary depending on individual factors such as the severity of your condition, kidney function, and other medications you may be taking. Your doctor will adjust the dosage as needed to achieve the desired therapeutic effect while minimizing potential side effects. Regular monitoring of blood sugar levels and kidney function is essential during treatment with 'DAPAGLIGEN V 10/100MG SR TABLET 10'S'.
  • Do not alter the prescribed dosage or discontinue the medication without consulting your doctor. Abruptly stopping the medication can lead to a sudden increase in blood sugar levels. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Always consult your healthcare provider for any concerns regarding your dosage or treatment plan. Take 'DAPAGLIGEN V 10/100MG SR TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of DAPAGLIGEN V 10/100MG SR TABLET 10'S?Arrow

  • If you miss a dose of DAPAGLIFLOZIN VILDAGLIPTIN 10/100MG SR TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store DAPAGLIGEN V 10/100MG SR TABLET 10'S?Arrow

  • Keep DAPAGLIGEN V 10/100MG SR TAB 1X10 away from the reach of children and pets.
  • Store DAPAGLIGEN V 10/100MG SR TAB 1X10 at room temperature.

Benefits of DAPAGLIGEN V 10/100MG SR TABLET 10'SArrow

  • Dapagliflozin and Vildagliptin combination, available as DAPAGLIGEN V 10/100MG SR TABLET 10'S, offers a dual approach to managing type 2 diabetes, providing synergistic benefits beyond what either medication could achieve alone. This combination therapy is designed to improve glycemic control by targeting different mechanisms involved in regulating blood sugar levels.
  • Dapagliflozin, an SGLT2 inhibitor, works by reducing the reabsorption of glucose in the kidneys, leading to increased glucose excretion through urine. This process helps lower blood glucose levels, particularly after meals. Furthermore, this mechanism is insulin-independent, meaning it can effectively lower blood sugar even in individuals with insulin resistance or reduced insulin production. By promoting glucose excretion, dapagliflozin can also contribute to weight loss and a reduction in blood pressure, offering additional cardiovascular benefits.
  • Vildagliptin, a DPP-4 inhibitor, enhances the levels of incretin hormones in the body. Incretins stimulate insulin release from the pancreas and reduce glucagon secretion, both of which help lower blood glucose levels. Vildagliptin's action is glucose-dependent, meaning it primarily works when blood sugar levels are elevated, reducing the risk of hypoglycemia. By improving insulin secretion and suppressing glucagon, vildagliptin complements dapagliflozin's mechanism, providing more comprehensive glycemic control.
  • The combination of dapagliflozin and vildagliptin in DAPAGLIGEN V 10/100MG SR TABLET 10'S offers several key benefits. Firstly, it provides superior glycemic control compared to either drug alone, helping patients achieve and maintain their target HbA1c levels. Secondly, it addresses multiple aspects of type 2 diabetes, including insulin resistance, impaired insulin secretion, and increased glucose reabsorption. Thirdly, it may offer additional benefits such as weight loss, blood pressure reduction, and improved cardiovascular health.
  • DAPAGLIGEN V 10/100MG SR TABLET 10'S is typically well-tolerated, but like all medications, it can have potential side effects. Common side effects may include urinary tract infections (UTIs) due to increased glucose in the urine, genital infections, and mild gastrointestinal symptoms. Vildagliptin is less likely to cause hypoglycemia compared to some other diabetes medications, but the risk can increase when used in combination with insulin or sulfonylureas. It is important for patients to discuss any concerns or side effects with their healthcare provider.
  • Overall, DAPAGLIGEN V 10/100MG SR TABLET 10'S offers a valuable treatment option for individuals with type 2 diabetes who require additional glycemic control beyond what can be achieved with monotherapy. Its dual mechanism of action, targeting both glucose excretion and incretin enhancement, provides comprehensive benefits for managing blood sugar levels and improving overall metabolic health. As always, this medication should be used under the guidance of a healthcare professional who can assess individual patient needs and monitor for any potential side effects. Weight management, reduction in blood pressure and cardiovascular risk reduction are other benefits.

How to use DAPAGLIGEN V 10/100MG SR TABLET 10'SArrow

  • DAPAGLIGEN V 10/100MG SR TABLET 10'S should be taken orally, usually once daily, preferably in the morning. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this could affect the extended-release properties and lead to altered drug absorption. It's recommended to take this medication at the same time each day to maintain consistent drug levels in your body.
  • Your doctor will determine the appropriate dosage based on your individual condition and response to treatment. It is crucial to follow your doctor's instructions precisely and not adjust the dosage without consulting them. Do not stop taking the medication even if you feel well, as this medication helps manage your condition, and stopping it abruptly could lead to worsening of your symptoms.
  • DAPAGLIGEN V 10/100MG SR TABLET 10'S can be taken with or without food. However, maintaining a consistent dietary pattern each day can help minimize potential gastrointestinal side effects. If you experience any nausea or stomach upset, try taking it with a small meal.
  • It is essential to monitor your blood sugar levels regularly as directed by your doctor, especially when you start taking this medication or if your dosage is adjusted. This helps to ensure that the medication is effectively controlling your blood sugar. Be aware of the symptoms of both high and low blood sugar and know what to do if they occur.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with DAPAGLIFLOZIN V and affect its effectiveness or increase the risk of side effects. Pay close attention to your body and report any unusual or concerning symptoms to your doctor promptly.

Quick Tips for DAPAGLIGEN V 10/100MG SR TABLET 10'SArrow

  • Take DAPAGLIGEN V 10/100MG SR TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once daily, preferably in the morning to minimize nighttime urination.
  • DAPAGLIGEN V 10/100MG SR TABLET 10'S is used to manage blood sugar levels in adults with type 2 diabetes. It combines two medications: dapagliflozin and vildagliptin. Dapagliflozin helps your kidneys remove glucose from your bloodstream, while vildagliptin increases insulin release and decreases glucagon secretion.
  • Stay well-hydrated while taking DAPAGLIGEN V 10/100MG SR TABLET 10'S. Dapagliflozin can increase urination, so drinking plenty of water helps prevent dehydration. Aim for at least 8-10 glasses of water per day, unless your doctor advises otherwise.
  • Monitor your blood sugar levels regularly as directed by your doctor. This will help you track how well the medication is working and allow your doctor to make any necessary adjustments to your treatment plan. Keep a log of your blood sugar readings to share with your healthcare provider.
  • Be aware of the potential side effects of DAPAGLIGEN V 10/100MG SR TABLET 10'S. Common side effects include urinary tract infections, yeast infections, and increased urination. More serious side effects can include ketoacidosis (a buildup of acids in the blood) and kidney problems. Contact your doctor immediately if you experience any unusual symptoms.
  • Maintain a healthy lifestyle while taking DAPAGLIGEN V 10/100MG SR TABLET 10'S. This includes eating a balanced diet, exercising regularly, and maintaining a healthy weight. These lifestyle changes can significantly improve your blood sugar control and overall health.
  • If you are scheduled for surgery or any medical procedure, inform your doctor that you are taking DAPAGLIGEN V 10/100MG SR TABLET 10'S. The medication may need to be temporarily discontinued to avoid complications.
  • Regular foot care is crucial when you have diabetes. Inspect your feet daily for any cuts, blisters, or sores. Keep your feet clean and dry, and wear comfortable shoes that fit well. Consult a podiatrist if you have any concerns about your foot health.
  • Discuss all other medications and supplements you are taking with your doctor before starting DAPAGLIGEN V 10/100MG SR TABLET 10'S. Certain medications can interact with DAPAGLIGEN V 10/100MG SR TABLET 10'S, potentially affecting its effectiveness or increasing the risk of side effects.
  • Store DAPAGLIGEN V 10/100MG SR TABLET 10'S at room temperature, away from heat, moisture, and direct sunlight. Keep the medication out of reach of children and pets.

Food Interactions with DAPAGLIGEN V 10/100MG SR TABLET 10'SArrow

  • DAPAGLIFLOZIN VILDAGLIPTIN (DAPAGLIGEN V 10/100MG SR TABLET 10'S) can be taken with or without food. However, it is important to take it at the same time each day to maintain consistent blood sugar levels. There are no specific food restrictions while taking this medication, but it is always advisable to follow a healthy diet as recommended by your doctor or dietician.

FAQs

What is DAPAGLIGEN V 10/100MG SR TABLET 10'S used for?Arrow

DAPAGLIGEN V 10/100MG SR TABLET 10'S is used to manage type 2 diabetes mellitus by lowering blood sugar levels. It combines two medications to improve glycemic control.

How does DAPAGLIGEN V 10/100MG SR TABLET 10'S work?Arrow

This tablet works through a dual mechanism: Dapagliflozin helps the kidneys excrete excess glucose through urine, while the other component enhances insulin sensitivity and reduces glucose production in the liver.

What are the common side effects of DAPAGLIGEN V 10/100MG SR TABLET 10'S?Arrow

Common side effects may include urinary tract infections, genital infections (in both men and women), increased urination, and sometimes dizziness. Consult your doctor if side effects persist or worsen.

Can I take DAPAGLIGEN V 10/100MG SR TABLET 10'S if I have kidney problems?Arrow

It is important to inform your doctor about any kidney problems before taking this medication. The dosage may need to be adjusted, or it may not be suitable for you depending on the severity of your kidney condition.

What should I do if I miss a dose of DAPAGLIGEN V 10/100MG SR TABLET 10'S?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Can DAPAGLIGEN V 10/100MG SR TABLET 10'S be taken with other diabetes medications?Arrow

DAPAGLIGEN V 10/100MG SR TABLET 10'S can be taken with other diabetes medications, but it is crucial to consult your doctor first. Combining medications may require dosage adjustments to avoid hypoglycemia (low blood sugar).

How should I store DAPAGLIGEN V 10/100MG SR TABLET 10'S?Arrow

Store DAPAGLIGEN V 10/100MG SR TABLET 10'S at room temperature, away from moisture and heat. Keep it out of reach of children.

Can DAPAGLIGEN V 10/100MG SR TABLET 10'S cause weight loss?Arrow

Some patients may experience modest weight loss while taking DAPAGLIGEN V 10/100MG SR TABLET 10'S, as it helps eliminate excess glucose through urine. However, it is not specifically a weight loss medication.

What are the symptoms of overdose of DAPAGLIGEN V 10/100MG SR TABLET 10'S?Arrow

Symptoms of overdose may include nausea, vomiting, abdominal pain, and hypoglycemia (low blood sugar). Seek immediate medical attention if you suspect an overdose.

Are there any specific dietary recommendations while taking DAPAGLIGEN V 10/100MG SR TABLET 10'S?Arrow

While taking this medication, it is important to follow a balanced diet that is low in sugar and refined carbohydrates. Regular exercise is also recommended to manage blood sugar levels effectively.

Can DAPAGLIGEN V 10/100MG SR TABLET 10'S affect my cholesterol levels?Arrow

Dapagliflozin, one of the components of this tablet, may have a mild effect on improving cholesterol levels, but it is not its primary function. Your doctor may monitor your cholesterol levels periodically.

Is DAPAGLIGEN V 10/100MG SR TABLET 10'S safe to use during pregnancy or breastfeeding?Arrow

DAPAGLIGEN V 10/100MG SR TABLET 10'S is generally not recommended during pregnancy or breastfeeding. Consult your doctor for alternative diabetes management options during these periods.

How long does it take for DAPAGLIGEN V 10/100MG SR TABLET 10'S to start working?Arrow

The effect of DAPAGLIGEN V 10/100MG SR TABLET 10'S on blood sugar levels can typically be observed within a few days of starting the medication. However, it may take several weeks to see the full therapeutic effect.

Can stress or illness affect how DAPAGLIGEN V 10/100MG SR TABLET 10'S works?Arrow

Yes, stress and illness can affect blood sugar levels, potentially influencing the effectiveness of DAPAGLIGEN V 10/100MG SR TABLET 10'S. Monitor your blood sugar more frequently during stressful times or when you are ill, and consult your doctor if needed.

Are there other brands with the same composition as DAPAGLIGEN V 10/100MG SR?Arrow

Yes, there might be other brands with the same composition (Dapagliflozin and another drug) manufactured by different pharmaceutical companies. Always check the composition and consult your doctor before switching brands.

References

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DrugBank: Dapagliflozin

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FDA Prescribing Information: FARXIGA (dapagliflozin)

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European Medicines Agency: Forxiga (dapagliflozin)

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PMC: Dapagliflozin: a review of its use in type 2 diabetes mellitus

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PMC: Dapagliflozin: An Update on its Pharmacology and Therapeutic Use in Type 2 Diabetes Mellitus

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PubChem: Dapagliflozin

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FDA Application: Dapagliflozin Propanediol

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Springer Link: Dapagliflozin: A sodium-glucose co-transporter 2 inhibitor for the treatment of type 2 diabetes

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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