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ZILDA D 10/100MG TABLET 10'S

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ZILDA D 10/100MG TABLET 10'S

By APRICA PHARMACEUTICALS PRIVATE LIMITED

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Content Reviewed By:

Dr. Rajesh Sharma

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About ZILDA D 10/100MG TABLET 10'S

  • ZILDA D 10/100MG TABLET is a powerful and effective medication designed to help manage Type 2 Diabetes Mellitus in adults. This innovative combination therapy aims to provide comprehensive blood sugar control, going beyond just lowering glucose levels to also support overall metabolic health. Tailored for individuals who require more intensive management of their blood sugar, ZILDA D 10/100MG helps to bring your glucose levels within a healthy range, reducing the risk of long-term diabetes complications. Its convenient formulation makes it an important tool in your diabetes care plan, working synergistically to deliver superior glycemic control.
  • The strength of ZILDA D 10/100MG lies in its dual-action formula, combining two distinct yet complementary active ingredients: Dapagliflozin (10mg) and Vildagliptin (100mg). Dapagliflozin belongs to a class of medications called SGLT2 inhibitors. It works by helping your kidneys remove excess glucose from your body through urine, effectively lowering blood sugar levels independently of insulin. This mechanism also offers additional benefits such as weight reduction and blood pressure management. Vildagliptin, a DPP-4 inhibitor, works differently by increasing the levels of natural hormones called incretins in your body. Incretins help to increase insulin production from the pancreas when blood sugar levels are high and decrease the amount of sugar the liver makes. By combining these two powerful mechanisms, ZILDA D 10/100MG provides a robust approach to managing your blood glucose, ensuring more consistent and effective control throughout the day.
  • ZILDA D 10/100MG TABLET is particularly beneficial for adults with Type 2 Diabetes who haven't achieved adequate blood sugar control with a single medication or who require the combined benefits of these two advanced therapies. Beyond significant reductions in HbA1c, this medication may also contribute to a healthy weight profile and support cardiovascular and renal health, which are crucial considerations for diabetes patients. Always remember to use ZILDA D 10/100MG TABLET as prescribed by your healthcare professional, alongside a balanced diet and regular exercise, to achieve the best possible outcomes in your diabetes management journey. Consult your doctor to understand if ZILDA D 10/100MG is the right choice for your specific health needs and to discuss any potential side effects.

Uses of ZILDA D 10/100MG TABLET 10'S

  • Type 2 Diabetes Management
  • Blood Sugar Control
  • Lowering High Blood Glucose
  • Preventing Diabetes Complications
  • Improving Glycemic Control
  • Adjunct to Diet and Exercise for Diabetes
  • Reducing HbA1c Levels

How ZILDA D 10/100MG TABLET 10'S Works

  • ZILDA D 10/100MG TABLET is a powerful medication designed to help individuals with Type 2 Diabetes manage their blood sugar levels effectively. It combines two advanced ingredients, Dapagliflozin (10mg) and Vildagliptin (100mg), each working through a unique mechanism to provide comprehensive glucose control. This dual-action approach targets different aspects of glucose regulation, offering a more robust solution for diabetes management.
  • Dapagliflozin, one of the key components, belongs to a class of medicines called SGLT2 inhibitors. Your kidneys naturally reabsorb sugar back into your bloodstream. Dapagliflozin works by blocking a specific protein in the kidneys called SGLT2 (Sodium-Glucose Co-Transporter 2). By inhibiting SGLT2, it prevents the kidneys from reabsorbing too much glucose. Instead, more glucose is expelled from your body through urine. This process helps to lower your blood sugar levels independently of insulin, making it a valuable mechanism, especially when insulin production might be impaired or insulin resistance is high. It also has the added benefit of promoting some weight loss due to the calorie loss from excreted glucose, and has shown positive effects on cardiovascular and renal health in studies for certain patient populations.
  • Vildagliptin, the second active ingredient, is a DPP-4 inhibitor. In your body, there are natural hormones called incretins (like GLP-1 and GIP) that play a crucial role in regulating blood sugar. These incretins are released after you eat and signal your pancreas to produce more insulin when blood sugar levels are high, and less glucagon (a hormone that raises blood sugar). Normally, an enzyme called DPP-4 quickly breaks down these beneficial incretin hormones. Vildagliptin works by blocking this DPP-4 enzyme, allowing incretin hormones to stay active longer in your system. This extended activity means your pancreas can produce more insulin in a glucose-dependent manner (only when blood sugar is high), and simultaneously reduce the release of glucagon, leading to a more controlled and stable blood sugar level.
  • The true power of ZILDA D 10/100MG TABLET lies in the synergy between Dapagliflozin and Vildagliptin. While Dapagliflozin works on the kidneys to remove excess sugar from the body, Vildagliptin works on the pancreas to optimize insulin production and suppress glucagon. This multi-pronged approach addresses the complexities of Type 2 Diabetes from different angles. By improving both glucose excretion and insulin sensitivity/production, ZILDA D helps achieve more consistent and significant reductions in HbA1c (a measure of long-term blood sugar control). This comprehensive action not only aids in better blood sugar management but also contributes to improved overall well-being for individuals living with Type 2 Diabetes. Always use ZILDA D as prescribed by your healthcare professional for optimal results.

Side Effects of ZILDA D 10/100MG TABLET 10'SArrow

ZILDA D 10/100MG TABLET is a medication primarily used to manage Type 2 Diabetes Mellitus. Like all medicines, it can cause side effects, though not everyone experiences them. It's important to be aware of these. **Common Side Effects (usually mild and transient):** * Nausea, vomiting, diarrhea, abdominal pain, indigestion, or a metallic taste in the mouth (especially common with Metformin component and often improve over time). * Headache, dizziness. * Stuffy or runny nose, sore throat (nasopharyngitis). **Less Common Side Effects:** * Tremors (shaking, especially if used with other diabetes medications like sulfonylureas). * Joint pain (arthralgia). * Swelling of hands, ankles, or feet (edema). * Skin rash or itching. **Rare but Serious Side Effects (seek immediate medical attention if you experience any of these):** * **Pancreatitis:** Severe and persistent stomach pain that may radiate to your back, with or without vomiting. * **Lactic Acidosis (Metformin related):** A very rare but serious metabolic complication, symptoms include unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or a slow heart rate. It is more likely in patients with kidney problems, liver disease, or severe dehydration. * **Liver Problems:** Symptoms like yellowing of the skin or eyes (jaundice), dark urine, pale stools, or unexplained tiredness. * **Severe Allergic Reactions:** Swelling of the face, lips, tongue, or throat, which may cause difficulty breathing or swallowing. * **Vitamin B12 Deficiency:** Long-term use of Metformin can lead to reduced Vitamin B12 levels, causing symptoms like fatigue, weakness, numbness or tingling in hands and feet (peripheral neuropathy). Always consult your doctor or pharmacist if any side effect bothers you or does not go away, or if you experience any serious symptoms.

Safety Advice for ZILDA D 10/100MG TABLET 10'SArrow

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Allergies

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Do not take Zilda D if you are allergic to any of its components (Vildagliptin, Metformin or other excipients). Seek immediate medical attention if you experience symptoms of an allergic reaction.

Dosage of ZILDA D 10/100MG TABLET 10'SArrow

  • ZILDA D 10/100MG TABLET 10'S is a medication commonly prescribed for the management of type 2 diabetes mellitus. It combines two active ingredients, Dapagliflozin (10mg) and Vildagliptin (100mg), which work through different mechanisms to help control blood sugar levels. Dapagliflozin belongs to the SGLT2 inhibitor class, promoting the removal of excess glucose through urine, while Vildagliptin is a DPP-4 inhibitor, increasing insulin release and decreasing glucagon levels. Understanding the recommended dosage is crucial for effective treatment and patient safety.
  • Typically, the recommended dosage for ZILDA D 10/100MG TABLET 10'S is one tablet taken orally once daily. This should ideally be taken in the morning, with or without food, as per your doctor's instructions. Consistency in taking the medication at the same time each day can help maintain stable blood sugar levels. It is vital not to exceed the prescribed dose or alter the frequency of administration without consulting your healthcare provider. This combination therapy offers a comprehensive approach to blood glucose control, often used when monotherapy is insufficient.
  • Patients should always adhere strictly to their physician's guidance regarding ZILDA D 10/100MG TABLET 10'S. Your doctor will determine the most appropriate dosage based on your individual medical condition, existing kidney function, liver function, and response to treatment. Regular monitoring of blood sugar levels and kidney function is essential while on this medication. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose; in that case, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. Always store the tablets at room temperature, away from direct light and moisture, and out of reach of children.
  • Take 'ZILDA D 10/100MG TABLET 10'S' only as per the prescription by your physician only. This medication is part of a broader diabetes management plan that includes diet modifications, regular exercise, and possibly other medications. It is not intended for type 1 diabetes or for treating diabetic ketoacidosis. Any side effects or concerns should be promptly reported to your doctor for guidance and adjustment if necessary. Always consult your healthcare provider for personalized advice regarding ZILDA D 10/100MG TABLET 10'S.

What if I miss my dose of ZILDA D 10/100MG TABLET 10'S?Arrow

  • If you miss a dose of ZILDA D 10/100MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a forgotten one. If you are unsure, please consult your doctor or pharmacist for advice.

How to store ZILDA D 10/100MG TABLET 10'S?Arrow

  • Keep ZILDA D 10/100MG TAB 1X10 away from the reach of children and pets.
  • Store ZILDA D 10/100MG TAB 1X10 at room temperature.

Benefits of ZILDA D 10/100MG TABLET 10'SArrow

  • ZILDA D 10/100MG TABLET 10'S stands as a groundbreaking solution in the comprehensive management of Type 2 Diabetes Mellitus. This innovative combination medicine brings together two highly effective active ingredients, Dapagliflozin (10mg) and Vildagliptin (100mg), each working through distinct yet complementary mechanisms to offer unparalleled benefits. Designed to provide robust blood sugar control, ZILDA D goes beyond simply lowering glucose levels; it offers a multi-faceted approach to improve overall metabolic health and reduce the risk of diabetes-related complications. For individuals seeking a powerful, convenient, and holistic approach to managing their Type 2 Diabetes, ZILDA D represents a significant step forward, aiming to enhance quality of life and promote long-term well-being.
  • One of the primary and most significant benefits of ZILDA D is its Superior Blood Sugar Control. Dapagliflozin, an SGLT2 inhibitor, works by enabling the kidneys to remove excess glucose from the body through urine, effectively lowering blood sugar levels independently of insulin. Simultaneously, Vildagliptin, a DPP-4 inhibitor, boosts the body's natural ability to produce more insulin when needed and reduces the amount of glucose produced by the liver, especially after meals. This dual action results in significant reductions in HbA1c (a key measure of long-term blood sugar control), helping patients achieve and maintain target glucose levels more effectively than with single-agent therapies. This synergistic effect ensures consistent and stable glycemic control throughout the day, mitigating the risks associated with high blood sugar fluctuations.
  • Beyond its exceptional glycemic control, ZILDA D offers notable advantages in Weight Management Support. The Dapagliflozin component contributes to modest weight loss by promoting the excretion of glucose (which contains calories) through urine. For many individuals with Type 2 Diabetes, managing weight is a crucial aspect of their health journey. This beneficial side effect can significantly contribute to a healthier body mass index, which in turn can improve insulin sensitivity and further aid in diabetes management. This makes ZILDA D a particularly attractive option for patients who may also be struggling with weight issues or are looking for a medication that supports their weight management goals.
  • Crucially, ZILDA D extends its benefits to Cardiovascular Protection. Clinical studies have demonstrated that Dapagliflozin provides significant heart health advantages, notably reducing the risk of hospitalization for heart failure and lowering the incidence of major adverse cardiovascular events (MACE) in patients with Type 2 Diabetes, especially those with established cardiovascular disease or multiple cardiovascular risk factors. This protective effect on the heart is a game-changer, addressing one of the most serious and common complications of diabetes. By safeguarding your cardiovascular system, ZILDA D helps you live a healthier, more active life, reducing the burden of heart-related conditions.
  • Furthermore, ZILDA D offers Kidney Health Support, a vital aspect often overlooked in diabetes management. The Dapagliflozin component has been shown to slow the progression of chronic kidney disease (CKD) in patients with Type 2 Diabetes, regardless of their history of cardiovascular disease. By reducing the workload on the kidneys and protecting their function, ZILDA D plays a critical role in preserving renal health, thereby preventing or delaying the onset of serious kidney complications that are frequently associated with long-term diabetes. This comprehensive protection underscores its value as a proactive therapy.
  • The convenience of ZILDA D cannot be overstated. By combining two powerful medications into a single tablet, it simplifies daily medication routines, significantly improving Patient Adherence and Convenience. Instead of taking multiple pills, patients can achieve comprehensive diabetes management with just one dose, making it easier to stick to their treatment plan. This streamlined approach not only enhances compliance but also reduces the pill burden, contributing to a more positive and manageable experience for individuals living with Type 2 Diabetes. This ease of use is a key factor in consistent treatment and better long-term outcomes.
  • In summary, ZILDA D 10/100MG TABLET 10'S is more than just a blood sugar lowering medication; it's a comprehensive diabetes management solution. Its combined mechanism of action provides superior glycemic control, offers significant weight management benefits, and delivers crucial cardiovascular and renal protection. By addressing multiple facets of Type 2 Diabetes, ZILDA D empowers patients to take proactive steps towards a healthier future, reducing the risk of debilitating complications and significantly improving their overall quality of life. Consult your healthcare professional to see if ZILDA D is the right choice for your diabetes management journey.

How to use ZILDA D 10/100MG TABLET 10'SArrow

  • Understanding how to properly use ZILDA D 10/100MG Tablet 10's is crucial for managing your blood sugar effectively. ZILDA D is a medication prescribed to help control high blood sugar levels in individuals with Type 2 Diabetes Mellitus. It's essential to follow your doctor's instructions precisely regarding its usage. This tablet is an oral medication, meaning it should be swallowed whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect its intended release and efficacy. Consistency is key when taking ZILDA D. Try to take your medicine at the same time each day to maintain a stable level of the drug in your body, which helps in better blood sugar control throughout the day and night.
  • ZILDA D 10/100MG Tablet is generally recommended to be taken with food. Taking it during or immediately after a meal can help reduce the chances of stomach upset, which some people might experience. Your doctor will determine the correct dosage and frequency for you, based on your medical condition, response to treatment, and other medications you might be taking. Never alter your dose or stop taking ZILDA D without consulting your healthcare provider, even if you feel well. Suddenly stopping the medication can lead to a dangerous rise in blood sugar levels, increasing your risk of serious complications like kidney damage, nerve problems, or vision loss. Regular monitoring of your blood sugar levels as advised by your doctor is also an integral part of your treatment plan while on ZILDA D.
  • If you happen to miss a dose of ZILDA D 10/100MG Tablet, take it as soon as you remember, provided it's not too close to the time for your next scheduled dose. If it's almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects. Always inform your doctor about all other medications, supplements, or herbal products you are currently using, as they might interact with ZILDA D. Furthermore, maintaining a healthy lifestyle, including a balanced diet and regular exercise, is vital in conjunction with your ZILDA D medication to achieve optimal blood sugar management. Store ZILDA D in a cool, dry place, away from direct sunlight and moisture, and keep it out of reach of children.

Quick Tips for ZILDA D 10/100MG TABLET 10'SArrow

  • Always take ZILDA D 10/100MG TABLET exactly as prescribed by your doctor. Do not alter the dose or stop the medication without consulting them, even if you feel better. Consistency is key for effective blood sugar management. Your doctor will advise on the best time to take it, often with meals, to optimize its effects and minimize potential side effects. Missing doses or taking extra can disrupt your blood sugar control and lead to complications.
  • Remember, ZILDA D works best when combined with a healthy lifestyle. This includes a balanced diet low in sugary foods and refined carbohydrates, regular physical activity, and maintaining a healthy weight. These lifestyle changes are crucial for managing Type 2 Diabetes and enhance the effectiveness of ZILDA D, helping you achieve better long-term blood sugar control and overall well-being. Consult a dietician for personalized meal plans.
  • Regularly monitor your blood sugar levels as advised by your doctor. This helps you and your doctor understand how ZILDA D is working and if any adjustments are needed. Keep a log of your readings and share it during your follow-up appointments. Be aware of symptoms of both high (hyperglycemia) and low (hypoglycemia) blood sugar. If you experience symptoms of hypoglycemia (dizziness, sweating, confusion), consume a quick source of sugar like glucose tablets or fruit juice immediately and inform your doctor.
  • Stay well-hydrated throughout the day, especially while taking ZILDA D, as some components might increase urination. Be aware of potential side effects, such as urinary tract infections (UTIs) or yeast infections (genital thrush), which can be more common with certain diabetes medications. Report any unusual symptoms, persistent discomfort, or signs of infection (e.g., burning sensation during urination, itching, discharge) to your doctor promptly. Early detection and treatment are important.
  • Always inform your doctor and pharmacist about all other medications, herbal supplements, and over-the-counter drugs you are currently taking or plan to take. This includes vitamins and traditional remedies. Some medications can interact with ZILDA D, potentially affecting its efficacy or increasing the risk of side effects. This comprehensive disclosure helps your healthcare team ensure your treatment plan is safe and effective, preventing unwanted drug interactions.
  • Know when to seek immediate medical attention. While ZILDA D is generally well-tolerated, rare but serious side effects can occur. Be vigilant for signs of diabetic ketoacidosis (DKA) or Fournier's gangrene, though extremely rare. Symptoms like nausea, vomiting, abdominal pain, excessive thirst, fruity breath, or severe pain/redness/swelling in the genital or perineal area warrant immediate medical consultation. Prompt action can be life-saving.

FAQs

What is ZILDA D 10/100MG Tablet used for?Arrow

ZILDA D 10/100MG Tablet is primarily used to treat Type 2 Diabetes Mellitus in adults. It helps to lower high blood sugar levels when diet and exercise alone are not enough.

What are the active ingredients in ZILDA D 10/100MG Tablet?Arrow

ZILDA D 10/100MG Tablet contains two active ingredients: Vildagliptin (10mg) and Metformin Hydrochloride (100mg).

How does ZILDA D 10/100MG Tablet work?Arrow

Vildagliptin works by increasing the levels of certain natural substances (incretins) that help control blood sugar. Metformin reduces glucose production in the liver, decreases glucose absorption from the intestines, and improves insulin sensitivity in the body. Together, they effectively lower blood sugar.

What is the recommended dosage of ZILDA D 10/100MG Tablet?Arrow

The dosage of ZILDA D 10/100MG Tablet is determined by your doctor based on your blood sugar control and medical condition. It's crucial to follow your doctor's instructions regarding dose and frequency.

Can ZILDA D 10/100MG Tablet be taken with food?Arrow

It is generally recommended to take ZILDA D 10/100MG Tablet with food to reduce gastrointestinal side effects, especially those associated with Metformin.

What are the common side effects of ZILDA D 10/100MG Tablet?Arrow

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste in the mouth, headache, and dizziness. These often improve over time.

Are there any serious side effects of ZILDA D 10/100MG Tablet?Arrow

Serious but rare side effects can include lactic acidosis (a serious build-up of lactic acid, primarily due to Metformin), pancreatitis, liver problems, and severe allergic reactions. Seek immediate medical attention if you experience symptoms like severe abdominal pain, persistent vomiting, yellowing of skin/eyes, or severe rash.

Who should not take ZILDA D 10/100MG Tablet?Arrow

ZILDA D 10/100MG Tablet should not be taken by patients with severe kidney disease, liver disease, severe heart failure, or those with a history of lactic acidosis. It's also contraindicated in patients with Type 1 Diabetes or diabetic ketoacidosis.

What should I do if I miss a dose of ZILDA D 10/100MG Tablet?Arrow

If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double the dose to compensate.

What happens if I overdose on ZILDA D 10/100MG Tablet?Arrow

Overdosing on ZILDA D 10/100MG Tablet can lead to severe hypoglycemia (very low blood sugar) or lactic acidosis. Symptoms of overdose may include extreme weakness, confusion, severe nausea/vomiting, rapid breathing, and muscle pain. Seek immediate medical help.

Can ZILDA D 10/100MG Tablet cause weight loss or gain?Arrow

Metformin, one of the components, is generally associated with stable weight or modest weight loss. Vildagliptin is usually weight-neutral. Significant weight changes are not typically expected with ZILDA D 10/100MG Tablet.

Is ZILDA D 10/100MG Tablet safe during pregnancy or breastfeeding?Arrow

ZILDA D 10/100MG Tablet is generally not recommended during pregnancy or breastfeeding unless strictly advised by a doctor, as there is limited data on its safety in these populations. Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Does ZILDA D 10/100MG Tablet interact with other medications?Arrow

Yes, it can interact with certain medications like diuretics, corticosteroids, thyroid hormones, certain anti-hypertensives, and alcohol. Always inform your doctor about all medications, supplements, and herbal products you are taking.

How should ZILDA D 10/100MG Tablet be stored?Arrow

Store ZILDA D 10/100MG Tablet at room temperature, away from moisture and direct heat. Keep it out of reach of children and pets. Do not freeze.

Can ZILDA D 10/100MG Tablet be used for Type 1 Diabetes?Arrow

No, ZILDA D 10/100MG Tablet is specifically indicated for Type 2 Diabetes Mellitus and is not effective for treating Type 1 Diabetes, where the body produces little to no insulin.

What lifestyle changes are recommended while taking ZILDA D 10/100MG Tablet?Arrow

To maximize the benefits of ZILDA D 10/100MG Tablet, it's crucial to maintain a healthy diet, engage in regular physical activity, and monitor your blood sugar levels as advised by your doctor. These lifestyle changes are integral to diabetes management.

Are there other brands with Vildagliptin and Metformin combination?Arrow

Yes, Vildagliptin and Metformin are combined in various other brands marketed by different manufacturers, such as Galvus Met (Novartis), Jalra M (USV), Zomelis Met (Abbott), and Gliptamet (Sun Pharma). The dosages might vary.

Can ZILDA D 10/100MG Tablet affect my kidney or liver function?Arrow

Yes, Metformin, one of its components, is primarily cleared by the kidneys, and its accumulation can cause lactic acidosis in patients with impaired kidney function. Vildagliptin is primarily metabolized by the kidneys too. Both components can rarely affect liver function. Regular monitoring of kidney and liver function tests may be required by your doctor.

Is ZILDA D 10/100MG Tablet a cure for diabetes?Arrow

No, ZILDA D 10/100MG Tablet is not a cure for Type 2 Diabetes. It is an anti-diabetic medication that helps manage blood sugar levels and control the disease. Long-term management involves medication, diet, exercise, and regular medical check-ups.

References

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FARXIGA (dapagliflozin) tablets, for oral use. Full Prescribing Information from U.S. Food and Drug Administration (FDA).

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GALVUS (vildagliptin) Summary of Product Characteristics (SmPC) from European Medicines Agency (EMA).

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Dapagliflozin in Patients with Heart Failure and Preserved Ejection Fraction. New England Journal of Medicine (NEJM).

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Vildagliptin for the treatment of type 2 diabetes mellitus: a review of the clinical evidence. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.

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Efficacy and safety of dapagliflozin and vildagliptin combination therapy in type 2 diabetes: A systematic review and meta-analysis. Diabetes, Obesity and Metabolism.

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Dapagliflozin: A Review of its Use in the Management of Type 2 Diabetes Mellitus. Drugs Journal.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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