DAPLO V TABLET 10'S

How DAPLO V TABLET 10'S Works

• DAPLO V TABLET 10'S is a combination medicine designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients, Dapagliflozin and Vildagliptin, each working through distinct mechanisms to achieve optimal glycemic control.
• **Dapagliflozin's Mechanism:** Dapagliflozin belongs to a class of medications called Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. The kidneys play a vital role in filtering glucose from the blood. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin selectively inhibits SGLT2, preventing the kidneys from reabsorbing glucose. As a result, excess glucose is excreted through urine, leading to a reduction in blood sugar levels. This process is also associated with a mild caloric loss, potentially aiding in weight management. Additionally, Dapagliflozin may contribute to modest reductions in blood pressure.
• **Vildagliptin's Mechanism:** Vildagliptin is a Dipeptidyl Peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as Glucagon-Like Peptide-1 (GLP-1) and Glucose-dependent Insulinotropic Polypeptide (GIP), are released from the gut in response to food intake. These hormones stimulate insulin release from the pancreas and suppress glucagon secretion from the liver, both of which help lower blood sugar levels. Vildagliptin inhibits DPP-4, prolonging the action of incretin hormones. This results in increased insulin secretion (in a glucose-dependent manner) and decreased glucagon secretion, ultimately leading to improved blood sugar control.
• **Synergistic Action:** The combination of Dapagliflozin and Vildagliptin offers a dual-pronged approach to managing blood sugar. Dapagliflozin reduces glucose reabsorption in the kidneys, while Vildagliptin enhances the effects of incretin hormones. This synergistic action can lead to better glycemic control compared to either medication used alone. By targeting different pathways involved in glucose regulation, DAPLO V TABLET 10'S helps to effectively lower blood sugar levels, particularly after meals.
• It is crucial to remember that DAPLO V TABLET 10'S is most effective when used in conjunction with a healthy diet and regular exercise. It is not a substitute for lifestyle modifications, but rather a tool to help manage blood sugar levels effectively. Always follow your doctor's instructions regarding dosage and usage.

Common side effects of Daplo V Tablet may include: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Hypoglycemia (low blood sugar), Genital infections (both male and female), Urinary tract infections (UTIs), Increased urination, Thirst, Constipation, Headache, Dizziness, Fatigue, Back pain, Joint pain. Less common but potentially serious side effects include: Diabetic ketoacidosis (DKA), Fournier's gangrene (a rare but serious infection of the genitals), Kidney problems, Allergic reactions (rash, itching, swelling), Increased cholesterol levels. This is not an exhaustive list, and it's important to consult with your doctor or pharmacist if you experience any unusual or concerning symptoms while taking Daplo V Tablet.

• If you miss a dose of DAPLO V TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep DAPLO V TAB 1X10 away from the reach of children and pets.
• Store DAPLO V TAB 1X10 at room temperature.

• Take DAPLO V exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Adherence to the prescribed regimen is crucial for managing your blood sugar and blood pressure effectively. Consistency in timing is also important; try to take it at the same time each day to maintain stable levels of the medication in your body.
• DAPLO V can cause dehydration, so drink plenty of water throughout the day, especially if you are physically active or in a hot environment. Staying hydrated helps your kidneys function properly and can reduce the risk of side effects like dizziness or lightheadedness. Monitor your urine color and frequency to ensure you are adequately hydrated.
• Monitor your blood sugar and blood pressure regularly, as directed by your doctor. Keep a log of your readings and share it with your healthcare provider during your appointments. This information helps them assess how well the medication is working and make any necessary adjustments to your treatment plan. Knowing your numbers empowers you to take control of your health.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, dizziness, and confusion. Carry a source of fast-acting sugar with you, such as glucose tablets or a small juice box, in case your blood sugar drops too low. If you experience these symptoms, check your blood sugar and take immediate action to raise it to a safe level. Inform your family and friends about the signs of hypoglycemia and how they can help you if needed.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking, as they may interact with DAPLO V. Certain medications can increase or decrease the effectiveness of DAPLO V, or increase your risk of side effects. Your doctor needs a complete picture of your medication regimen to ensure your safety and optimize your treatment. This includes over-the-counter drugs and any alternative therapies you are using.
• Pay attention to your diet. Make sure you are eating balanced meals with the right portions. A healthy diet helps the medicine work better.
• Be careful when driving or using machines, especially when you start taking DAPLO V. This medicine can affect your blood sugar and blood pressure, which may make you feel dizzy.
• If you notice any new or unusual symptoms, tell your doctor right away. This helps them find any problems early and take care of them.
• Always bring DAPLO V with you when you travel, and keep a note from your doctor about why you need the medicine. This is helpful in case of any emergencies.
• Store DAPLO V in a cool, dry place away from sunlight and moisture. Keeping your medicine in the right conditions helps it stay effective.

• DAPLO V TABLET 10'S can be taken with or without food. Its absorption is not significantly affected by food intake. However, it is generally recommended to take it at a consistent time each day to maintain stable blood sugar levels and to adhere to any dietary recommendations provided by your healthcare provider for managing diabetes.