DILNIP TM 50 TABLET 10'S

How DILNIP TM 50 TABLET 10'S Works

• DILNIP TM 50 Tablet contains a combination of Cilnidipine and Telmisartan, which work synergistically to effectively lower blood pressure. Cilnidipine is a calcium channel blocker that primarily acts on blood vessels. It inhibits the influx of calcium ions into vascular smooth muscle cells. This calcium influx is essential for the contraction of these cells, leading to vasoconstriction (narrowing of blood vessels). By blocking calcium channels, Cilnidipine causes the smooth muscle cells in the blood vessel walls to relax. This relaxation widens the blood vessels, reducing the resistance against which the heart has to pump, and consequently, lowering blood pressure. Cilnidipine's action is particularly prominent in the arteries, helping to reduce arterial pressure.
• Telmisartan, on the other hand, is an angiotensin II receptor blocker (ARB). Angiotensin II is a potent vasoconstrictor, meaning it causes blood vessels to narrow. It also stimulates the release of aldosterone, a hormone that increases sodium and water retention by the kidneys, further contributing to increased blood pressure. Telmisartan works by selectively blocking the binding of angiotensin II to its receptors, specifically the AT1 receptors, found in various tissues such as the blood vessels, heart, and kidneys. By blocking these receptors, Telmisartan prevents angiotensin II from exerting its vasoconstricting effects and from stimulating aldosterone release.
• The combined action of Cilnidipine and Telmisartan provides a dual mechanism for blood pressure control. Cilnidipine directly relaxes blood vessels by blocking calcium influx, while Telmisartan counteracts the effects of angiotensin II, a key hormone in blood pressure regulation. This combination results in a more effective and sustained reduction in blood pressure compared to using either medication alone. Furthermore, Telmisartan's action on the AT1 receptors also provides benefits beyond blood pressure control, such as protecting the kidneys and heart from damage associated with high blood pressure. The synergistic effect helps to maintain blood pressure within a healthy range, reducing the risk of cardiovascular events such as heart attack, stroke, and kidney problems. Always follow your physician's instructions regarding dosage and usage of this medication.

Common side effects of DILNIP TM 50 Tablet may include headache, flushing (feeling of warmth), nausea, dizziness, and edema (swelling). Less common side effects can be fatigue, palpitations, gastrointestinal disturbances like constipation or diarrhea, skin rash, itching, and muscle cramps. Rare but serious side effects may involve liver problems (e.g., jaundice), changes in heart rhythm (arrhythmias), low blood pressure (hypotension), and allergic reactions.

• If you miss a dose of DILNIP TM 50 TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep DILNIP TM 10/50/40MG TAB 1X10 away from the reach of children and pets.
• Store DILNIP TM 10/50/40MG TAB 1X10 at room temperature.

• DILNIP TM 50 TABLET 10'S can be taken with or without food. However, it is important to take it at the same time each day to maintain consistent blood levels of the medication. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it can increase the level of DILNIP TM 50 TABLET 10'S in your blood and potentially increase the risk of side effects. If you have any concerns about specific food interactions, consult your doctor or pharmacist.