ESOMEFA DSR CAPSULE 10'S

How ESOMEFA DSR CAPSULE 10'S Works

• ESOMEFA DSR CAPSULE 10'S is a combination medication designed to treat gastroesophageal reflux disease (GERD) and peptic ulcers. It works through a dual mechanism, addressing both acid production and the motility of the gastrointestinal tract. The key ingredients are Esomeprazole and Domperidone, each playing a crucial role in alleviating symptoms and promoting healing.
• Esomeprazole, a proton pump inhibitor (PPI), is the primary component responsible for reducing acid secretion in the stomach. Parietal cells in the stomach lining contain proton pumps (H+/K+ ATPase) that are responsible for pumping hydrogen ions into the stomach lumen, which lowers the pH, making it acidic. Esomeprazole works by irreversibly binding to these proton pumps and inhibiting their function. This reduces the amount of acid produced, relieving symptoms such as heartburn, acid regurgitation, and indigestion. By reducing the acidity in the stomach, Esomeprazole also promotes the healing of ulcers and prevents further damage to the esophageal lining in GERD.
• Domperidone, on the other hand, is a dopamine antagonist that primarily affects the upper gastrointestinal tract. It enhances gastric motility by increasing the frequency and amplitude of gastric contractions, thereby accelerating gastric emptying. Dopamine typically inhibits acetylcholine release, which in turn reduces gastrointestinal motility. Domperidone blocks dopamine receptors, which facilitates acetylcholine release, leading to enhanced peristalsis. This action helps to prevent acid reflux by reducing the amount of time food and acid remain in the stomach. Additionally, Domperidone helps to alleviate nausea and vomiting often associated with GERD and peptic ulcers.
• The combined action of Esomeprazole and Domperidone in ESOMEFA DSR CAPSULE 10'S provides a synergistic effect. Esomeprazole reduces acid production, while Domperidone promotes faster gastric emptying and reduces the likelihood of acid reflux. This dual approach not only provides symptomatic relief but also addresses the underlying causes of GERD and peptic ulcers. The sustained-release (DSR) formulation ensures that the medication is released gradually, providing prolonged relief and maintaining therapeutic levels throughout the day. Patients taking ESOMEFA DSR CAPSULE 10'S typically experience a significant reduction in symptoms, improved quality of life, and enhanced healing of gastrointestinal lesions.

Common side effects of ESOMEFA DSR CAPSULE may include headache, dizziness, dry mouth, nausea, vomiting, stomach pain, constipation, flatulence (gas), and diarrhea. Less common but more serious side effects can include allergic reactions (rash, itching, swelling), muscle cramps, changes in heart rate, liver problems (dark urine, yellowing of skin/eyes), kidney problems, and nervous system disorders (tremors, anxiety, confusion). Long-term use may lead to Vitamin B12 deficiency, bone fractures, and an increased risk of certain infections.

• If you miss a dose of Esomefa DSR Capsule, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep ESOMEFA DSR CAP 1X10 away from the reach of children and pets.
• Store ESOMEFA DSR CAP 1X10 at room temperature.

• Take ESOMEFA DSR Capsule 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as this could affect its effectiveness and increase the risk of side effects. Generally, it is taken once daily, 30-60 minutes before a meal.
• For optimal absorption and effectiveness, swallow ESOMEFA DSR Capsule 10'S whole with a glass of water. Avoid crushing, chewing, or opening the capsule, as this can disrupt the controlled-release mechanism and alter how the medicine works.
• ESOMEFA DSR Capsule 10'S is designed to reduce stomach acid production and relieve symptoms like heartburn and acid reflux. It's most effective when taken consistently at the same time each day. Missing doses can lead to a return of symptoms.
• Inform your doctor about all other medications, supplements, or herbal products you are currently taking before starting ESOMEFA DSR Capsule 10'S. This helps prevent potential drug interactions that could reduce the efficacy of ESOMEFA DSR or increase the risk of adverse effects. Pay special attention to drugs like blood thinners or antifungals.
• If you experience any persistent or worsening side effects such as headache, diarrhea, nausea, or abdominal pain while taking ESOMEFA DSR Capsule 10'S, consult your doctor promptly. They can assess your condition and provide appropriate guidance or adjust your treatment plan. Long term usage can lead to Vitamin B12 deficiency, so do consult your doctor.

• ESOMEFA DSR CAPSULE 10'S should be taken on an empty stomach, ideally 30-60 minutes before a meal.
• Food can significantly reduce the absorption of esomeprazole, the active ingredient in ESOMEFA DSR, thereby decreasing its effectiveness.
• Taking it before food allows for optimal absorption and reduces acid production more effectively.
• Avoid taking it with or immediately after food, especially fatty meals, as this can further decrease absorption.