NEKSIUM D 40MG CAPSULE 10'S
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NEKSIUM D 40MG CAPSULE 10'S
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NEKSIUM D 40MG CAPSULE 10'S

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NEKSIUM D 40MG CAPSULE 10'S

By PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About NEKSIUM D 40MG CAPSULE 10'S

  • NEKSIUM D 40MG CAPSULE 10'S is a combination medicine used to treat gastroesophageal reflux disease (GERD). It works by reducing the amount of acid produced in the stomach and promoting the movement of food through the stomach, thereby relieving heartburn, acid indigestion, and associated discomfort.
  • Each capsule contains Esomeprazole and Domperidone. Esomeprazole is a proton pump inhibitor (PPI) that decreases the production of stomach acid. Domperidone is a prokinetic agent that accelerates gastric emptying and reduces nausea or vomiting. This synergistic action helps in providing comprehensive relief from GERD symptoms.
  • This medication is typically prescribed for individuals experiencing frequent heartburn, regurgitation, and difficulty swallowing due to acid reflux. It's important to take NEKSIUM D 40MG CAPSULE 10'S as directed by your healthcare provider, usually before meals. The duration of treatment depends on the severity of your condition and your response to the medication.
  • Before using NEKSIUM D 40MG CAPSULE 10'S, inform your doctor about any existing medical conditions, allergies, or medications you are currently taking. Common side effects may include headache, diarrhea, abdominal pain, and dry mouth. If you experience any persistent or severe side effects, seek medical advice promptly.
  • NEKSIUM D 40MG CAPSULE 10'S offers a convenient and effective way to manage GERD symptoms. With its dual-action formula, it provides both acid suppression and enhanced gastric motility for optimal relief. Always follow your doctor's instructions and read the patient information leaflet carefully before starting treatment.

Uses of NEKSIUM D 40MG CAPSULE 10'S

  • Treatment of Gastroesophageal Reflux Disease (GERD)
  • Treatment of Peptic Ulcers
  • Treatment of Acidity
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of Heartburn due to Acidity
  • Treatment of Stomach Pain due to Acidity
  • Treatment of Erosive Esophagitis
  • Prevention of NSAID-induced Ulcers

How NEKSIUM D 40MG CAPSULE 10'S Works

  • NEKSIUM D 40MG CAPSULE 10'S is a combination medication designed to treat gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid production. It combines two active ingredients: Esomeprazole and Domperidone, each working through distinct mechanisms to alleviate symptoms and promote healing.
  • Esomeprazole, a proton pump inhibitor (PPI), is the primary acid-suppressing component. Parietal cells in the stomach lining contain proton pumps, which are responsible for secreting hydrochloric acid into the stomach. Esomeprazole selectively binds to these proton pumps, irreversibly inhibiting their function. By blocking acid secretion at its source, esomeprazole significantly reduces the acidity of the stomach contents. This provides relief from heartburn, acid regurgitation, and other GERD symptoms. Furthermore, the reduced acidity creates a more favorable environment for the healing of any existing esophageal damage, such as erosions or ulcers.
  • Domperidone, the second active ingredient, is a prokinetic agent. It primarily works by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) of the brain and in the gastrointestinal tract. Dopamine is a neurotransmitter that can slow down gastric emptying. By blocking dopamine's action, domperidone promotes faster gastric emptying, reducing the amount of time stomach contents remain in the stomach. Additionally, it increases the tone of the lower esophageal sphincter (LES), the muscular valve that separates the esophagus from the stomach. A stronger LES helps prevent stomach acid from flowing back up into the esophagus, further reducing acid reflux.
  • The synergistic action of Esomeprazole and Domperidone addresses multiple aspects of GERD. Esomeprazole reduces acid production, while Domperidone accelerates gastric emptying and strengthens the LES. This combined approach provides more comprehensive symptom relief and promotes healing compared to using either medication alone. By reducing acid exposure in the esophagus and preventing backflow, NEKSIUM D 40MG CAPSULE 10'S effectively manages GERD and improves the patient's overall quality of life. It's important to note that this medication should be taken as prescribed by a healthcare professional, and the duration of treatment will vary depending on the individual's condition and response to therapy.

Side Effects of NEKSIUM D 40MG CAPSULE 10'SArrow

Common side effects of NEKSIUM D 40MG CAPSULE may include headache, diarrhea, stomach pain, flatulence, nausea, vomiting, and constipation. Less common but potentially serious side effects include allergic reactions (rash, itching, swelling), changes in liver function, bone fracture, hypomagnesemia (low magnesium levels), vitamin B12 deficiency, and lupus erythematosus. Other possible side effects are dry mouth, dizziness, and skin reactions. This is not an exhaustive list, and it's important to consult with your doctor or pharmacist if you experience any unusual or bothersome symptoms while taking NEKSIUM D 40MG CAPSULE.

Safety Advice for NEKSIUM D 40MG CAPSULE 10'SArrow

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Allergies

Consult a Doctor

Do not use Neksium D 40mg Capsule if you are allergic to it. Please consult your doctor.

Dosage of NEKSIUM D 40MG CAPSULE 10'SArrow

  • The recommended dosage of NEKSIUM D 40MG CAPSULE 10'S varies depending on the individual's condition, severity of symptoms, and response to treatment. It is crucial to adhere strictly to your doctor's instructions regarding dosage and duration of treatment. Typically, NEKSIUM D 40MG CAPSULE 10'S is taken once daily, preferably in the morning, on an empty stomach, at least 30 minutes before a meal. This timing optimizes absorption and effectiveness of the medication. Do not crush, chew, or break the capsule; swallow it whole with a glass of water.
  • For patients with gastroesophageal reflux disease (GERD), the usual starting dose is one capsule daily for a period of 4 to 8 weeks. Your doctor may adjust the dosage based on symptom control and endoscopic findings. For long-term maintenance therapy, the dosage may be reduced to the lowest effective dose to prevent recurrence of symptoms. In cases of Zollinger-Ellison syndrome, the dosage is highly individualized and may be significantly higher, depending on the amount of acid being produced by the stomach. Regular monitoring by your physician is essential to ensure appropriate dosage adjustments.
  • If you miss a dose of NEKSIUM D 40MG CAPSULE 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Always consult your doctor if you have any questions or concerns about your dosage. Prolonged use of NEKSIUM D 40MG CAPSULE 10'S should be under medical supervision, as it may be associated with certain side effects. Take 'NEKSIUM D 40MG CAPSULE 10'S' only as per the prescription by your physician only

What if I miss my dose of NEKSIUM D 40MG CAPSULE 10'S?Arrow

  • If you miss a dose of NEKSIUM D 40MG CAPSULE 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store NEKSIUM D 40MG CAPSULE 10'S?Arrow

  • Keep NEKSIUM D 40MG CAP 1X10 away from the reach of children and pets.
  • Store NEKSIUM D 40MG CAP 1X10 at room temperature.

Benefits of NEKSIUM D 40MG CAPSULE 10'SArrow

  • NEKSIUM D 40MG CAPSULE 10'S is a powerful medication combining esomeprazole and domperidone, designed to provide comprehensive relief from gastrointestinal issues. Esomeprazole, a proton pump inhibitor (PPI), works by reducing the amount of acid produced in the stomach, while domperidone is a prokinetic agent that accelerates gastric emptying. This dual action makes NEKSIUM D 40MG CAPSULE 10'S highly effective in treating various conditions related to acid reflux and delayed gastric emptying.
  • One of the primary benefits of NEKSIUM D 40MG CAPSULE 10'S is its ability to alleviate symptoms of gastroesophageal reflux disease (GERD). GERD occurs when stomach acid frequently flows back into the esophagus, causing heartburn, regurgitation, and inflammation. By reducing acid production, esomeprazole helps to prevent acid reflux, thereby relieving heartburn and allowing the esophagus to heal. Domperidone complements this action by speeding up the movement of food through the digestive tract, reducing the likelihood of acid backing up into the esophagus.
  • NEKSIUM D 40MG CAPSULE 10'S is also beneficial for individuals experiencing peptic ulcers. These ulcers, which can develop in the stomach or duodenum, are often caused by Helicobacter pylori infection or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). Esomeprazole helps to heal peptic ulcers by reducing acid exposure, creating an environment conducive to tissue repair. Additionally, the medication can prevent the recurrence of ulcers, particularly when used in conjunction with antibiotics to eradicate H. pylori.
  • Furthermore, NEKSIUM D 40MG CAPSULE 10'S can effectively manage dyspepsia, a condition characterized by indigestion, bloating, and discomfort in the upper abdomen. Domperidone helps to relieve these symptoms by promoting gastric emptying, which reduces feelings of fullness and bloating after meals. Esomeprazole contributes by minimizing acid-related discomfort, making NEKSIUM D 40MG CAPSULE 10'S a valuable option for individuals with chronic indigestion.
  • The prokinetic properties of domperidone in NEKSIUM D 40MG CAPSULE 10'S also make it useful in treating gastroparesis, a condition in which the stomach empties too slowly. This delayed emptying can lead to nausea, vomiting, and abdominal pain. By increasing the rate at which the stomach empties, domperidone helps to alleviate these symptoms and improve overall digestive function. The combination with esomeprazole ensures that any acid-related issues are also addressed simultaneously.
  • NEKSIUM D 40MG CAPSULE 10'S offers a convenient and effective solution for individuals suffering from multiple gastrointestinal disorders. Its dual-action mechanism provides comprehensive relief from acid reflux, ulcers, dyspepsia, and gastroparesis, improving the quality of life for those affected by these conditions. Regular use, as directed by a healthcare professional, can help manage symptoms and prevent complications associated with chronic digestive issues.

How to use NEKSIUM D 40MG CAPSULE 10'SArrow

  • NEKSIUM D 40MG CAPSULE 10'S should be taken exactly as prescribed by your doctor. It's typically recommended to take this medication on an empty stomach, at least 30 minutes before a meal, preferably in the morning. This ensures optimal absorption of the drug. Swallow the capsule whole with a glass of water; do not crush, chew, or break it, as this can affect how the medication is released and absorbed in your body.
  • The dosage and duration of treatment will depend on your specific medical condition and how you respond to the medication. It's crucial to adhere to your doctor's instructions and not adjust the dosage yourself, even if you start feeling better. Completing the full course of treatment is important to ensure the underlying condition is effectively managed.
  • If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
  • Avoid consuming alcohol while taking NEKSIUM D 40MG CAPSULE 10'S, as it can increase the risk of certain side effects. Also, inform your doctor about all other medications, supplements, or herbal products you are taking to prevent any potential drug interactions. If you experience any unusual or severe side effects, such as persistent stomach pain, black stools, or allergic reactions, seek immediate medical attention.
  • For elderly patients or individuals with kidney or liver problems, dose adjustments may be necessary. It is very important to discuss any pre-existing medical conditions with your doctor before starting NEKSIUM D 40MG CAPSULE 10'S. Regular follow-up appointments with your doctor are essential to monitor your progress and adjust the treatment plan if needed. Store the capsules in a cool, dry place away from direct sunlight and moisture, and keep them out of reach of children.

Quick Tips for NEKSIUM D 40MG CAPSULE 10'SArrow

  • Take NEKSIUM D 40MG CAPSULE 10'S exactly as prescribed by your doctor. Do not crush, chew, or open the capsule. Swallow it whole with a glass of water, preferably 30-60 minutes before a meal. Consistency is key for optimal results.
  • If you miss a dose of NEKSIUM D 40MG CAPSULE 10'S, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Inform your doctor about all other medications, supplements, or herbal products you are currently taking before starting NEKSIUM D 40MG CAPSULE 10'S. Certain medications can interact with it, affecting its efficacy or increasing the risk of side effects. Pay special attention to blood thinners, antifungals, and certain heart medications.
  • Be aware of potential side effects. Common side effects may include headache, diarrhea, nausea, flatulence, and abdominal pain. If any of these side effects persist or worsen, consult your doctor. More serious side effects are rare, but seek immediate medical attention if you experience symptoms such as severe allergic reactions (rash, itching, swelling), unusual bleeding or bruising, or signs of kidney problems.
  • NEKSIUM D 40MG CAPSULE 10'S is designed to reduce stomach acid production and relieve symptoms like heartburn and acid reflux. Lifestyle adjustments like avoiding trigger foods (spicy, fatty, acidic), eating smaller meals, and not lying down immediately after eating can complement the effects of the medication. Elevating the head of your bed can also help prevent nighttime reflux. Consider these adjustments for better symptom control alongside taking the medicine.

Food Interactions with NEKSIUM D 40MG CAPSULE 10'SArrow

  • NEKSIUM D 40MG CAPSULE 10'S should be taken on an empty stomach, preferably 30-60 minutes before a meal.
  • Taking it with food may reduce its effectiveness.
  • Avoid consuming large meals or high-fat foods immediately before or after taking this medication.

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FAQs

What is the use of NEKSIUM D 40MG CAPSULE 10'S?Arrow

NEKSIUM D 40MG CAPSULE 10'S is used to treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. It reduces the amount of acid in the stomach and provides relief from acidity, heartburn, and stomach pain.

How does NEKSIUM D 40MG CAPSULE work?Arrow

NEKSIUM D 40MG CAPSULE contains esomeprazole and domperidone. Esomeprazole is a proton pump inhibitor (PPI) that reduces acid production in the stomach, while domperidone is an anti-emetic that increases the motility of the stomach and intestines.

What are the common side effects of NEKSIUM D 40MG CAPSULE?Arrow

Common side effects of NEKSIUM D 40MG CAPSULE include nausea, vomiting, stomach pain, diarrhea, constipation, and headache.

Can NEKSIUM D 40MG CAPSULE be taken with or without food?Arrow

NEKSIUM D 40MG CAPSULE is usually recommended to be taken before food.

Is it safe to take NEKSIUM D 40MG CAPSULE during pregnancy?Arrow

It is important to consult a doctor before taking NEKSIUM D 40MG CAPSULE during pregnancy.

What is the dosage of NEKSIUM D 40MG CAPSULE?Arrow

The dosage of NEKSIUM D 40MG CAPSULE is determined by the doctor. Usually, it is taken once a day.

Can NEKSIUM D 40MG CAPSULE be used for a long time?Arrow

It is important to consult a doctor before using NEKSIUM D 40MG CAPSULE for a long time.

What happens if I miss a dose of NEKSIUM D 40MG CAPSULE?Arrow

If you miss a dose of NEKSIUM D 40MG CAPSULE, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Can NEKSIUM D 40MG CAPSULE interact with other medications?Arrow

NEKSIUM D 40MG CAPSULE can interact with certain medications. Therefore, it is important to tell the doctor about all your medications.

How to store NEKSIUM D 40MG CAPSULE?Arrow

Store NEKSIUM D 40MG CAPSULE at room temperature, away from moisture and sunlight.

What happens if I overdose on NEKSIUM D 40MG CAPSULE?Arrow

If you overdose on NEKSIUM D 40MG CAPSULE, contact a doctor immediately.

Does NEKSIUM D 40MG CAPSULE cause dizziness?Arrow

In some cases, NEKSIUM D 40MG CAPSULE can cause dizziness.

Can I drink alcohol with NEKSIUM D 40MG CAPSULE?Arrow

Drinking alcohol with NEKSIUM D 40MG CAPSULE may increase side effects.

Is NEKSIUM D 40MG CAPSULE safe for breastfeeding women?Arrow

Breastfeeding women should consult a doctor before taking NEKSIUM D 40MG CAPSULE.

Is Rabeprazole the same as NEKSIUM D 40MG CAPSULE?Arrow

Rabeprazole and NEKSIUM D 40MG CAPSULE are both proton pump inhibitors, but they contain different active ingredients. NEKSIUM D 40MG CAPSULE contains esomeprazole, while rabeprazole contains rabeprazole.

References

Book Icon

NEXIUM (esomeprazole magnesium) delayed-release capsules, delayed-release oral suspension prescribing information. This is the official prescribing information from the FDA, containing details on indications, dosage, contraindications, warnings, precautions, adverse reactions, drug interactions, use in specific populations, and clinical studies.

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Book Icon

European Medicines Agency (EMA) assessment report for Nexium. Provides a comprehensive overview of the scientific evaluation of Nexium, including details on its efficacy, safety, and quality.

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Book Icon

Esomeprazole: A comprehensive review. Published in Therapeutic Advances in Gastroenterology, this review article provides a detailed overview of esomeprazole, including its pharmacology, pharmacokinetics, clinical efficacy, and safety.

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Book Icon

DrugBank entry for Esomeprazole. Provides detailed information on the drug's chemical structure, mechanism of action, pharmacokinetics, and therapeutic uses.

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Book Icon

Esomeprazole. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. This is a regularly updated review article that goes over pharmacology, uses and potential side effects.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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