GLITARIS M 15MG TABLET 10'S

How GLITARIS M 15MG TABLET 10'S Works

• GLITARIS M 15MG TABLET 10'S is a combination medicine containing Pioglitazone and Metformin, both of which are oral antidiabetic drugs. This medication is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus, especially when diet and exercise alone are not sufficient. Understanding how each component works is crucial to appreciating the overall efficacy of GLITARIS M.
• Pioglitazone belongs to a class of drugs called thiazolidinediones (TZDs). It primarily works by increasing the body's sensitivity to insulin. Insulin is a hormone produced by the pancreas that helps glucose (sugar) enter cells to be used for energy. In individuals with type 2 diabetes, cells become resistant to insulin, leading to elevated blood sugar levels. Pioglitazone targets this insulin resistance at the cellular level, mainly in muscle, fat, and liver tissues. It activates a receptor called PPARγ (peroxisome proliferator-activated receptor gamma) inside these cells. Activation of PPARγ leads to increased expression of genes involved in glucose and lipid metabolism. This results in:
• - Enhanced glucose uptake and utilization in muscles, reducing blood sugar levels after meals and during exercise.
• - Decreased glucose production by the liver, further contributing to lower blood sugar levels throughout the day.
• - Improved fat storage and distribution, which can have a positive impact on overall metabolic health.
• Metformin, on the other hand, belongs to a class of drugs called biguanides. Its primary mechanism of action involves:
• - Decreasing glucose production in the liver. The liver normally produces glucose to maintain blood sugar levels, especially during fasting or between meals. Metformin suppresses this glucose production, preventing excessive build-up of sugar in the bloodstream.
• - Increasing insulin sensitivity in peripheral tissues (like muscle), similar to Pioglitazone, though through different pathways.
• - Slowing down the absorption of glucose from the intestines after a meal. This helps to prevent rapid spikes in blood sugar levels following food intake.
• By combining Pioglitazone and Metformin, GLITARIS M addresses multiple aspects of insulin resistance and glucose metabolism dysfunction in type 2 diabetes. Pioglitazone improves insulin sensitivity in peripheral tissues and reduces liver glucose output, while Metformin complements this by further reducing liver glucose production and improving glucose uptake. This synergistic effect leads to better blood sugar control compared to using either medication alone.
• It's important to note that GLITARIS M is most effective when used in conjunction with a healthy diet and regular exercise. These lifestyle modifications are fundamental to managing type 2 diabetes. Furthermore, patients should adhere to their doctor's instructions regarding dosage and monitoring of blood sugar levels to ensure optimal therapeutic outcomes and minimize the risk of potential side effects.

Possible side effects of Glitaris M 15mg Tablet may include: * **Common:** Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness. * **Uncommon:** Constipation, skin rash, itching, urticaria (hives), photosensitivity (increased sensitivity to sunlight), blurred vision, edema (swelling), weight gain, fatigue, weakness, upper respiratory tract infection. * **Rare:** Liver problems (e.g., jaundice), blood disorders (e.g., anemia, thrombocytopenia), lactic acidosis (a buildup of lactic acid in the body), pancreatitis, Stevens-Johnson syndrome (a severe skin reaction), angioedema (swelling of the face, lips, tongue, or throat).

• If you miss a dose of GLITARIS M 15MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep GLITARIS M 15MG TAB 1X10 away from the reach of children and pets.
• Store GLITARIS M 15MG TAB 1X10 at room temperature.

• Take GLITARIS M 15MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting them, as this can affect your blood sugar levels and overall health. Consistency is key to managing your diabetes effectively.
• It's best to take GLITARIS M 15MG TABLET 10'S with food, preferably at the same time each day. This helps to minimize potential stomach upset and ensures consistent absorption of the medication. Avoid skipping meals, as this can lead to hypoglycemia (low blood sugar) when taking this medication.
• Regularly monitor your blood sugar levels as directed by your healthcare provider while taking GLITARIS M 15MG TABLET 10'S. Keeping a log of your readings will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Report any significant changes or concerns to your doctor promptly.
• Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. GLITARIS M 15MG TABLET 10'S works best when combined with lifestyle modifications. Focus on incorporating fiber-rich foods, lean proteins, and healthy fats into your diet. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
• Be aware of the symptoms of hypoglycemia (low blood sugar) such as shakiness, sweating, dizziness, confusion, and rapid heartbeat. Carry a source of fast-acting sugar with you, such as glucose tablets or fruit juice, in case you experience these symptoms. Inform your family and friends about how to recognize and treat hypoglycemia so they can assist you if needed. Also, inform your doctor if you experience frequent or severe hypoglycemic episodes.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration is essential for overall health and can also help regulate blood sugar levels. Limit sugary drinks, which can negatively impact your blood sugar control.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. Drug interactions can affect how GLITARIS M 15MG TABLET 10'S works, so it's crucial to provide your doctor with a complete list of everything you are taking. This includes over-the-counter medications and herbal remedies.
• Attend all scheduled appointments with your doctor and other healthcare providers. Regular check-ups are important for monitoring your health and making sure that your diabetes is well-managed. Your doctor may order blood tests or other tests to assess your overall health and adjust your treatment plan as needed.
• Store GLITARIS M 15MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Check the expiration date on the packaging and do not use the medication if it has expired.
• If you are planning to have surgery or any medical procedure, inform your doctor that you are taking GLITARIS M 15MG TABLET 10'S. Your doctor may need to adjust your medication dosage or temporarily discontinue it before the procedure.

• GLITARIS M 15MG TABLET 10'S can be taken with or without food, but it is best to take it at the same time each day to maintain consistent blood sugar levels. Consistent timing helps ensure optimal medication effectiveness. However, avoid excessive alcohol consumption while taking this medication, as it can increase the risk of low blood sugar (hypoglycemia).