PIOZAR MF 15/500MG TABLET 10'S
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PIOZAR MF 15/500MG TABLET 10'SPIOZAR MF 15/500MG TABLET 10'SPIOZAR MF 15/500MG TABLET 10'SPIOZAR MF 15/500MG TABLET 10'S
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PIOZAR MF 15/500MG TABLET 10'S

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PIOZAR MF 15/500MG TABLET 10'S

By SPECTRA THERAPEUTICS PRIVATE LIMITED

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65.2

₹55.42

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About PIOZAR MF 15/500MG TABLET 10'S

  • PIOZAR MF 15/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control in adults when used along with diet and exercise. This medication contains two active ingredients: Pioglitazone and Metformin.
  • Pioglitazone belongs to a class of drugs called thiazolidinediones (TZDs). It works by increasing the body's sensitivity to insulin, a natural hormone that helps regulate blood sugar levels. By making the body more responsive to insulin, pioglitazone helps lower blood sugar levels.
  • Metformin is a biguanide that decreases glucose production in the liver and improves insulin sensitivity. It also helps to reduce the amount of glucose absorbed from the intestines. Metformin is a commonly prescribed medication for type 2 diabetes and is often used as a first-line treatment.
  • This combination medication helps to manage blood sugar levels more effectively than either medication used alone. It's typically taken once or twice daily with meals. Your doctor will determine the appropriate dosage based on your individual needs and response to treatment.
  • PIOZAR MF 15/500MG TABLET is used in conjunction with lifestyle changes such as a healthy diet and regular exercise to achieve optimal blood sugar control. It is important to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly while taking this medication. Potential side effects can include weight gain, edema (swelling), and gastrointestinal issues. Consult with your doctor about potential risks and benefits.

Uses of PIOZAR MF 15/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Managing insulin resistance in polycystic ovary syndrome (PCOS)
  • Reducing the risk of heart disease (in some patients)

How PIOZAR MF 15/500MG TABLET 10'S Works

  • PIOZAR MF 15/500MG TABLET is a combination medication containing Pioglitazone and Metformin, two oral antidiabetic agents used to manage type 2 diabetes mellitus. This medication works through complementary mechanisms to improve glycemic control in patients with insulin resistance.
  • Pioglitazone belongs to a class of drugs called thiazolidinediones (TZDs). It primarily works by increasing the body's sensitivity to insulin. Insulin is a hormone produced by the pancreas that helps glucose (sugar) enter cells to be used for energy. In type 2 diabetes, cells become resistant to insulin, leading to elevated blood sugar levels. Pioglitazone activates a nuclear receptor called PPARγ (peroxisome proliferator-activated receptor gamma), which is found in fat cells, muscle cells, and the liver. Activation of PPARγ leads to increased expression of genes involved in glucose and lipid metabolism. This results in several beneficial effects, including increased glucose uptake and utilization in muscles and fat tissue, decreased glucose production in the liver, and improved insulin sensitivity. By enhancing insulin sensitivity, pioglitazone helps lower blood sugar levels and improve overall glycemic control.
  • Metformin is a biguanide that works differently from pioglitazone. Its primary mechanism of action is to reduce glucose production in the liver. The liver normally produces glucose, especially during fasting or between meals, to maintain blood sugar levels. Metformin suppresses this hepatic glucose production by inhibiting gluconeogenesis (the process of making glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, metformin improves insulin sensitivity to some extent by increasing glucose uptake and utilization in peripheral tissues. It also slows down the absorption of glucose from the intestines. Unlike some other diabetes medications, metformin does not stimulate insulin secretion, which reduces the risk of hypoglycemia (low blood sugar).
  • By combining pioglitazone and metformin, PIOZAR MF 15/500MG TABLET addresses multiple aspects of type 2 diabetes. Pioglitazone improves insulin sensitivity, while metformin reduces glucose production in the liver and enhances insulin sensitivity peripherally. This synergistic effect helps lower blood sugar levels more effectively than either medication alone. Furthermore, the combination may have beneficial effects on lipid profiles, such as reducing triglycerides and increasing HDL cholesterol. It is important to use PIOZAR MF 15/500MG TABLET as directed by your healthcare provider and to follow a healthy diet and exercise program to achieve optimal blood sugar control.

Side Effects of PIOZAR MF 15/500MG TABLET 10'SArrow

Possible side effects of PIOZAR MF 15/500MG Tablet may include: Common: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, weight gain, upper respiratory tract infection, edema (swelling). Uncommon: Visual disturbances, anemia, lactic acidosis (rare but serious), liver problems, hypersensitivity reactions (rash, itching, hives). Rare: Bladder cancer, macular edema. This is not an exhaustive list. Consult your doctor if you experience any unusual symptoms.

Safety Advice for PIOZAR MF 15/500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use PIOZAR MF 15/500MG TABLET 10'S if you are allergic to it.

Dosage of PIOZAR MF 15/500MG TABLET 10'SArrow

  • The recommended dosage of PIOZAR MF 15/500MG TABLET 10'S is individualized and depends on various factors, including your blood sugar levels, overall health, and response to treatment. Typically, the starting dose is one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects. Your doctor may gradually increase the dosage, usually at intervals of one to two weeks, until the desired blood sugar control is achieved.
  • The maximum recommended daily dose of pioglitazone is 45 mg, and metformin is 2000 mg. It is crucial not to exceed the prescribed dosage. Adhere strictly to your doctor's instructions regarding the timing and frequency of tablet intake. Consistency in taking PIOZAR MF 15/500MG TABLET 10'S at the same time(s) each day helps maintain stable blood sugar levels.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. It is important to maintain a healthy lifestyle while taking PIOZAR MF 15/500MG TABLET 10'S, including regular exercise, a balanced diet, and monitoring your blood sugar levels as directed by your healthcare provider. Regular check-ups with your doctor are also essential to assess your progress and adjust the dosage if needed.
  • Take 'PIOZAR MF 15/500MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of PIOZAR MF 15/500MG TABLET 10'S?Arrow

  • If you miss a dose of PIOZAR MF 15/500MG TABLET 10'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store PIOZAR MF 15/500MG TABLET 10'S?Arrow

  • Keep PIOZAR MF 15/500MG TAB 1X10 away from the reach of children and pets.
  • Store PIOZAR MF 15/500MG TAB 1X10 at room temperature.

Benefits of PIOZAR MF 15/500MG TABLET 10'SArrow

  • PIOZAR MF 15/500MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It effectively lowers blood sugar levels and improves the body's response to insulin. This dual action helps manage the symptoms and long-term complications associated with diabetes.
  • The primary benefit of PIOZAR MF 15/500MG TABLET 10'S lies in its ability to regulate blood glucose levels. Pioglitazone, one of its active ingredients, enhances insulin sensitivity in peripheral tissues such as muscles and fat, allowing cells to utilize glucose more effectively. Metformin, the other active ingredient, reduces glucose production in the liver and improves insulin sensitivity. Together, they provide a synergistic effect in controlling blood sugar.
  • By effectively managing blood sugar levels, PIOZAR MF 15/500MG TABLET 10'S helps reduce the risk of several diabetes-related complications. These include cardiovascular diseases such as heart attack and stroke, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). Maintaining stable blood sugar levels is crucial for preventing or delaying the onset of these serious health issues.
  • This medication can also contribute to improved energy levels and reduced fatigue often experienced by individuals with poorly controlled diabetes. By helping the body use glucose more efficiently, PIOZAR MF 15/500MG TABLET 10'S ensures that cells receive the necessary fuel to function optimally, leading to increased vitality and a better overall quality of life.
  • PIOZAR MF 15/500MG TABLET 10'S may also help improve cholesterol levels in some patients. Pioglitazone has been shown to increase levels of high-density lipoprotein (HDL) cholesterol, often referred to as 'good' cholesterol, which can protect against heart disease. However, it's important to note that individual responses may vary, and regular monitoring of cholesterol levels is recommended.
  • Another important advantage of PIOZAR MF 15/500MG TABLET 10'S is its convenient oral administration. As a tablet, it is easy to take and can be incorporated into a daily routine, promoting better adherence to the prescribed treatment plan. Consistency in taking the medication as directed by a healthcare professional is essential for achieving optimal results in managing diabetes.
  • Furthermore, PIOZAR MF 15/500MG TABLET 10'S can be used as part of a comprehensive diabetes management plan that includes lifestyle modifications such as diet and exercise. When combined with a healthy lifestyle, this medication can significantly improve glycemic control and reduce the need for higher doses of other diabetes medications. Always consult with your doctor for personalized advice on diet and exercise.

How to use PIOZAR MF 15/500MG TABLET 10'SArrow

  • PIOZAR MF 15/500MG TABLET 10'S should be taken orally, preferably with a meal, to minimize the risk of stomach upset. It is crucial to adhere to your doctor's prescribed dosage and schedule for optimal results. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. Consistency is key, so try to take it at the same time each day to maintain a steady level of medication in your bloodstream.
  • Before starting PIOZAR MF 15/500MG TABLET 10'S, inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart issues, or if you are pregnant or breastfeeding. Also, disclose all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, as they may interact with PIOZAR MF. Regular monitoring of blood sugar levels is essential while on this medication. Your doctor may also recommend periodic liver function tests and kidney function tests to monitor your overall health and the effectiveness of the treatment.
  • If you miss a dose of PIOZAR MF 15/500MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Lifestyle modifications, such as a healthy diet, regular exercise, and weight management, are crucial while taking this medication to effectively manage your diabetes. Always follow your doctor's advice and report any unusual side effects or concerns promptly.
  • The duration of treatment with PIOZAR MF 15/500MG TABLET 10'S will be determined by your doctor based on your individual needs and response to the medication. Do not stop taking the medication abruptly without consulting your doctor, as this may lead to a worsening of your condition. Store PIOZAR MF 15/500MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture, and keep it out of reach of children.

Quick Tips for PIOZAR MF 15/500MG TABLET 10'SArrow

  • Take PIOZAR MF 15/500MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider, as this could lead to fluctuations in your blood sugar levels and potentially serious health consequences. Consistency is key for managing your diabetes effectively.
  • Administer PIOZAR MF 15/500MG TABLET 10'S with food to minimize the risk of stomach upset. Metformin, one of the active ingredients, can sometimes cause gastrointestinal side effects. Taking it with meals helps to slow down absorption and reduce these side effects. If you still experience discomfort, talk to your doctor.
  • Monitor your blood sugar levels regularly as directed by your doctor or diabetes educator. PIOZAR MF 15/500MG TABLET 10'S helps control blood sugar, but regular monitoring is crucial to ensure the medication is working effectively and to make any necessary adjustments to your treatment plan. Keep a log of your readings to share with your healthcare team.
  • Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. PIOZAR MF 15/500MG TABLET 10'S is most effective when combined with lifestyle changes. Focus on whole grains, lean proteins, fruits, and vegetables. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Consult a dietitian or certified diabetes educator for personalized guidance.
  • Be aware of the symptoms of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar). PIOZAR MF 15/500MG TABLET 10'S can affect your blood sugar levels. Knowing the symptoms of both conditions will help you take prompt action. Carry a source of fast-acting glucose, such as glucose tablets or fruit juice, to treat hypoglycemia. Contact your doctor if you experience frequent or severe episodes of either condition.

FAQs

What is PIOZAR MF 15/500MG TABLET 10'S?Arrow

PIOZAR MF 15/500MG TABLET 10'S is a combination of two medicines: Pioglitazone and Metformin. It is used to treat type 2 diabetes mellitus when diet and exercise alone are not sufficient to control blood sugar levels.

What is PIOZAR MF 15/500MG TABLET 10'S used for?Arrow

It is used to treat type 2 diabetes mellitus. It works by increasing the body's sensitivity to insulin and decreasing the amount of glucose produced by the liver.

What are the common side effects of PIOZAR MF 15/500MG TABLET 10'S?Arrow

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and headache.

Is PIOZAR MF 15/500MG TABLET 10'S safe for kidneys?Arrow

PIOZAR MF 15/500MG TABLET 10'S should be used with caution in patients with kidney disease. Dose adjustment may be needed. Please consult your doctor.

Is PIOZAR MF 15/500MG TABLET 10'S safe for the liver?Arrow

PIOZAR MF 15/500MG TABLET 10'S should be used with caution in patients with liver disease. Dose adjustment or regular liver function tests may be needed. Please consult your doctor.

How to store PIOZAR MF 15/500MG TABLET 10'S?Arrow

Store it at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

Is PIOZAR MF 15/500MG TABLET 10'S safe during pregnancy?Arrow

The safety of PIOZAR MF 15/500MG TABLET 10'S during pregnancy is not established. Consult your doctor if you are pregnant or planning to become pregnant.

Is PIOZAR MF 15/500MG TABLET 10'S safe during breastfeeding?Arrow

It is not known whether PIOZAR MF 15/500MG TABLET 10'S is excreted in breast milk. Consult your doctor before breastfeeding.

What to do if you miss a dose of PIOZAR MF 15/500MG TABLET 10'S?Arrow

If you miss a dose of PIOZAR MF 15/500MG TABLET 10'S, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can I consume alcohol with PIOZAR MF 15/500MG TABLET 10'S?Arrow

Consuming alcohol with PIOZAR MF 15/500MG TABLET 10'S can lower blood sugar levels and may cause other side effects. Therefore, it is advisable not to consume alcohol with this medicine.

Does PIOZAR MF 15/500MG TABLET 10'S interact with other medications?Arrow

PIOZAR MF 15/500MG TABLET 10'S can interact with certain other medications, such as insulin, sulfonylureas, and certain antibiotics. Inform your doctor about all your medications to avoid any potential interactions.

How long does it take for PIOZAR MF 15/500MG TABLET 10'S to start working?Arrow

It may take a few weeks for PIOZAR MF 15/500MG TABLET 10'S to start lowering blood sugar levels.

Can I take PIOZAR MF 15/500MG TABLET 10'S with or without food?Arrow

PIOZAR MF 15/500MG TABLET 10'S is usually recommended to be taken with food to minimize the chance of stomach upset.

Can PIOZAR MF 15/500MG TABLET 10'S cause weight gain?Arrow

Yes, PIOZAR MF 15/500MG TABLET 10'S can cause weight gain in some patients. Talk to your doctor if you are concerned about this.

What happens if I overdose on PIOZAR MF 15/500MG TABLET 10'S?Arrow

An overdose of PIOZAR MF 15/500MG TABLET 10'S can cause low blood sugar levels (hypoglycemia) and other serious side effects. Seek immediate medical attention if you suspect you have overdosed on this medication.

References

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DrugBank: Metformin - Mechanism of Action, Metabolism, and Drug Interactions

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FDA Prescribing Information for Metformin Hydrochloride Tablets

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European Medicines Agency (EMA) - Actos (pioglitazone) EPAR

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FDA Prescribing Information for Pioglitazone Hydrochloride Tablets

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DeFronzo RA. Pharmacologic therapy for type 2 diabetes: targeting insulin resistance and beta-cell dysfunction. Ann Intern Med. 1999;131(4):281-303.

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Diabetes Prevention Program Research Group. Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 10-year follow-up: the Diabetes Prevention Program Outcomes Study. Lancet. 2009;374(9702):1677-86.

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UpToDate: Pioglitazone drug information

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UpToDate: Metformin drug information

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