PIOZ MF 15MG TABLET 10'S

How PIOZ MF 15MG TABLET 10'S Works

• PIOZ MF 15MG TABLET 10'S is a combination medicine containing Pioglitazone and Metformin. It's designed to help control blood sugar levels in adults with type 2 diabetes. It works through multiple mechanisms to improve glycemic control.
• Pioglitazone, a thiazolidinedione (TZD), increases the body's sensitivity to insulin. Insulin is a hormone that helps glucose (sugar) from the blood enter cells to be used for energy. In type 2 diabetes, cells become resistant to insulin, leading to high blood sugar levels. Pioglitazone works by activating a receptor called PPARγ (peroxisome proliferator-activated receptor gamma) inside cells. Activation of PPARγ leads to increased expression of genes involved in glucose and lipid metabolism. This results in improved insulin sensitivity in muscle, liver, and fat tissues. By making these tissues more responsive to insulin, pioglitazone helps glucose enter cells more effectively, lowering blood sugar levels. It also reduces glucose production in the liver.
• Metformin, a biguanide, primarily works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues. It reduces hepatic gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Metformin also slows down the absorption of glucose from the intestines after a meal, further contributing to lower postprandial (after-meal) blood sugar spikes. Additionally, metformin increases insulin sensitivity by enhancing glucose uptake and utilization in peripheral tissues like muscle. This helps to utilize the available insulin more efficiently. Furthermore, Metformin has also been shown to have a positive impact on lipid profiles and can lead to modest weight loss in some individuals.
• In combination, Pioglitazone and Metformin address different aspects of insulin resistance and glucose metabolism, providing a synergistic effect in lowering blood sugar levels. Pioglitazone improves insulin sensitivity in the periphery, while Metformin reduces glucose production in the liver and enhances peripheral insulin sensitivity. This dual mechanism helps to effectively control blood sugar levels in individuals with type 2 diabetes. This medicine is usually prescribed along with diet and exercise to achieve the best results.
• It is important to note that PIOZ MF 15MG TABLET 10'S does not stimulate the pancreas to produce more insulin, therefore, it carries a lower risk of hypoglycemia (low blood sugar) compared to some other diabetes medications. However, it is essential to follow your doctor's instructions regarding dosage, diet, and exercise while taking this medicine to manage your blood sugar effectively and minimize potential side effects.

The following side effects may occur while taking PIOZ MF 15MG TABLET 10'S: * Hypoglycemia (low blood sugar) - especially when used with other diabetes medications. * Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite. * Edema (swelling) - particularly in the legs and ankles. * Weight gain. * Upper respiratory tract infection. * Headache. * Muscle pain. * Visual disturbances. * Anemia. * Increased risk of bone fractures (in women). * Liver problems (rare). * Heart failure (rare). * Skin reactions like rash, itching or hives (rare).

• If you miss a dose of PIOZ MF 15MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep PIOZ MF 15MG TAB 1X10 away from the reach of children and pets.
• Store PIOZ MF 15MG TAB 1X10 at room temperature.

• Take PIOZ MF 15MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once or twice daily with meals to help manage blood sugar levels effectively. Consistency is key for optimal results.
• PIOZ MF 15MG TABLET 10'S combines pioglitazone and metformin, each addressing insulin resistance and glucose production differently. Understand that this medicine works best when combined with a healthy diet and regular exercise. Focus on incorporating balanced meals and physical activity into your daily routine for enhanced blood sugar control. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
• Be aware of potential side effects. Common side effects may include nausea, diarrhea, headache, or upper respiratory tract infection. More serious side effects can include symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, sudden weight gain), liver problems (such as persistent nausea/vomiting, stomach/abdominal pain, dark urine, yellowing eyes/skin), or lactic acidosis. Report any persistent or severe side effects to your doctor immediately.
• Regular monitoring is crucial. While taking PIOZ MF 15MG TABLET 10'S, your doctor will likely monitor your blood sugar levels, kidney function, and liver function regularly. Attend all scheduled appointments and undergo the recommended blood tests. These tests help ensure the medication is working effectively and to detect any potential problems early. Also, inform your doctor about any other medications, supplements, or herbal remedies you are taking to avoid potential drug interactions.
• Understand the signs of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar). Symptoms of hypoglycemia may include shakiness, sweating, confusion, dizziness, or rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, frequent urination, blurred vision, or fatigue. Knowing these signs and how to manage them can prevent complications. Always carry a source of fast-acting glucose (such as glucose tablets or fruit juice) in case of hypoglycemia.