GLYCLAZAR MR 60MG TABLET 10'S

How GLYCLAZAR MR 60MG TABLET 10'S Works

• GLYCLAZAR MR 60MG TABLET 10'S is an oral hypoglycemic medication primarily used to manage type 2 diabetes mellitus, especially when diet and exercise alone are insufficient to control blood sugar levels. Its active ingredient, Gliclazide, belongs to the sulfonylurea class of drugs. Understanding how GLYCLAZAR MR works involves several key mechanisms:
• 1. **Stimulating Insulin Release:** Gliclazide's primary action is to stimulate the beta cells in the pancreas to release more insulin. Insulin is a hormone crucial for regulating blood glucose levels. It allows glucose to move from the bloodstream into cells, where it can be used for energy. In type 2 diabetes, either the pancreas doesn't produce enough insulin, or the body's cells become resistant to its effects. Gliclazide helps overcome the insulin deficiency by prompting the pancreas to secrete more of it.
• 2. **Improving Insulin Sensitivity:** In addition to stimulating insulin release, Gliclazide can also improve the sensitivity of peripheral tissues (such as muscle and fat) to insulin. This means that the insulin that is released is more effective at facilitating glucose uptake into cells. This dual action helps lower blood glucose levels more effectively.
• 3. **Mechanism at the Cellular Level:** At the cellular level, Gliclazide works by binding to specific receptors on the beta cells of the pancreas. This binding leads to the closure of ATP-sensitive potassium channels. The closure of these channels causes the cell membrane to depolarize, which in turn opens voltage-gated calcium channels. The influx of calcium ions into the beta cells triggers the release of insulin.
• 4. **MR (Modified Release) Formulation:** GLYCLAZAR MR 60MG is formulated as a modified-release tablet. This means that the medication is released slowly and steadily over an extended period. This helps to maintain a more consistent blood glucose level throughout the day, reducing the risk of sudden spikes or drops in blood sugar. The modified-release formulation also allows for once-daily dosing, which improves patient compliance.
• 5. **Considerations:** It's important to note that GLYCLAZAR MR is most effective when used in conjunction with a healthy diet and regular exercise. Patients should follow their healthcare provider's instructions regarding diet, exercise, and blood glucose monitoring. Regular monitoring is essential to ensure that the medication is effectively controlling blood sugar levels and to watch for any potential side effects, such as hypoglycemia (low blood sugar).
• In summary, GLYCLAZAR MR 60MG TABLET 10'S works by stimulating insulin release from the pancreas, improving insulin sensitivity, and providing a sustained release of the medication to maintain stable blood glucose levels throughout the day. This makes it a valuable tool in managing type 2 diabetes mellitus.

Possible side effects of GLYCLAZAR MR 60MG TABLET 10'S may include: Hypoglycemia (low blood sugar) with symptoms like sweating, shakiness, anxiety, rapid heartbeat, confusion, and dizziness; Nausea; Vomiting; Diarrhea; Abdominal pain; Constipation; Visual disturbances; Skin reactions such as rash, itching, and hives; Changes in blood cell counts; Liver problems (rare). Consult your doctor if you experience any persistent or severe side effects.

• If you miss a dose of GLYCLAZAR MR 60MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep GLYCLAZAR MR 60MG TAB 1X10 away from the reach of children and pets.
• Store GLYCLAZAR MR 60MG TAB 1X10 at room temperature.

• Take GLYCLAZAR MR 60MG TABLET 10'S as prescribed by your doctor, usually once daily. It's best to take it at the same time each day, preferably with breakfast, to maintain consistent blood sugar levels.
• Follow your doctor's diet and exercise recommendations while taking GLYCLAZAR MR 60MG TABLET 10'S. This medicine works best when combined with a healthy lifestyle to manage your blood sugar effectively. Do not skip meals.
• If you experience symptoms of low blood sugar (hypoglycemia) such as sweating, shaking, rapid heartbeat, or confusion, consume a quick source of sugar like juice or candy and inform your doctor immediately. Always carry a sugary snack with you.
• Regularly monitor your blood sugar levels as directed by your doctor. This will help you and your doctor track how well the medicine is working and make necessary adjustments to your treatment plan.
• Inform your doctor about all other medications, supplements, or herbal remedies you are taking, as they may interact with GLYCLAZAR MR 60MG TABLET 10'S. This includes over-the-counter medications as well. Also, discuss any planned surgeries or medical procedures with your doctor.
• Be aware of the potential side effects of GLYCLAZAR MR 60MG TABLET 10'S, such as nausea, vomiting, or abdominal pain. If these side effects persist or worsen, consult your doctor promptly. Do not drive or operate machinery if you feel dizzy or have blurred vision.

• It is advisable to take GLYCLAZAR MR 60MG TABLET 10'S at the same time each day, preferably with breakfast, to maintain consistent blood sugar levels. While taking this medication, maintain a consistent carbohydrate intake and avoid skipping meals. Consult your doctor or dietician for specific dietary advice tailored to your needs.