IRINOT 40MG/2ML INJECTION
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IRINOT 40MG/2ML INJECTION
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IRINOT 40MG/2ML INJECTION

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IRINOT 40MG/2ML INJECTION

By KHANDELWAL LABORATORIES PRIVATE LIMITED

MRP

₹

1808.44

₹442

75.56 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About IRINOT 40MG/2ML INJECTION

  • IRINOT 40MG/2ML INJECTION belongs to a class of medications known as anti-cancer medicines or cytostatics. Its active ingredient is Irinotecan hydrochloride trihydrate. It is used in adults to treat advanced colon and rectal cancer, either on its own or in combination with other chemotherapy drugs. Colon and rectal cancer are more common in people over 50, and are often caused by a mix of genetic and environmental factors. This medication works by interfering with the growth of cancer cells, eventually destroying them and slowing the spread of cancer within the body.
  • The most common side effects of this injection are myelosuppression (which means the bone marrow doesn't make enough red blood cells, white blood cells, and platelets) and diarrhea. Other frequent side effects of IRINOT 40MG/2ML INJECTION include nausea, vomiting, abdominal pain, constipation, anemia, pain, fatigue, fever, infections (including sepsis), abnormal bilirubin levels, hair loss, and weight loss. Tell your doctor if these side effects bother you or don't go away. Let your doctor know right away if you have chronic inflammatory bowel disease, a bowel obstruction, or if you have recently received any live vaccines.
  • Before starting treatment, tell your doctor if you are allergic to Irinotecan or any of the other ingredients in the injection. Also, tell them if you have any liver problems (like jaundice), kidney or heart problems, asthma, high blood pressure, high cholesterol, or severe diarrhea. It's also important to let your doctor know if you smoke or have ever had radiation therapy.
  • Tell your doctor about all medicines, herbs, and supplements you are taking. Both men and women need to use effective birth control while receiving this treatment to prevent pregnancy. Your doctor will do blood tests before and during treatment to check how IRINOT 40MG/2ML INJECTION is affecting your blood counts and blood chemistry. Regular check ups with your doctor are crucial for ensuring the treatment is going as planned and to manage any potential side effects effectively. It's also important to maintain a healthy diet and stay hydrated throughout the treatment process.

Uses of IRINOT 40MG/2ML INJECTION

  • Treatment of metastatic cancer of the colon and rectum (large intestine).

Side Effects of IRINOT 40MG/2ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects include early and late diarrhea, allergic reactions, kidney impairment, lung problems, and low levels of RBC, WBC, and platelets in the blood. Common side effects include nausea, vomiting, abdominal pain, constipation, diarrhea, anemia, pain, fatigue, fever, infections including sepsis, abnormal bilirubin levels, hair loss, and weight loss.

  • Early and late diarrhea
  • Allergic reactions
  • Kidney impairment
  • Lung problems
  • Low levels of RBC, WBC, and platelets in the blood
  • Nausea, vomiting, abdominal pain
  • Constipation
  • Diarrhea
  • Anemia
  • Pain
  • Fatigue
  • Fever, infections including sepsis
  • Abnormal bilirubin levels
  • Hair loss
  • Weight loss

Safety Advice for IRINOT 40MG/2ML INJECTIONArrow

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Pregnancy

UNSAFE

IRINOT 40MG/2ML INJECTION is unsafe during pregnancy as it may harm the developing baby. Women with potential childbearing use effective contraceptives during and after six months after treatment.

Dosage of IRINOT 40MG/2ML INJECTIONArrow

  • Always adhere to your doctor's instructions when it comes to IRINOT 40MG/2ML INJECTION. This medication is administered intravenously, meaning it's given directly into your vein by a trained healthcare professional. It is crucial that you do not attempt to self-administer this injection. Before commencing treatment with IRINOT 40MG/2ML INJECTION, your doctor will likely recommend a DNA test to assess how your body might respond to the drug. This helps them tailor the treatment to your specific needs.
  • The dosage of IRINOT 40MG/2ML INJECTION and the duration of treatment are determined by several factors, including your age, body weight, and the specific characteristics of your disease. Your physician will carefully consider these factors to determine the most appropriate dosage regimen for you. It's important to openly discuss any concerns or questions you have regarding your treatment plan with your doctor to ensure you understand the process and are comfortable with it.
  • Following the prescribed dosage schedule is essential for achieving the best possible outcome from IRINOT 40MG/2ML INJECTION treatment. Missing doses or altering the dosage without consulting your doctor can impact the drug's effectiveness and may lead to unwanted side effects. Therefore, ensure you attend all scheduled appointments and adhere strictly to your doctor's recommendations.

How to store IRINOT 40MG/2ML INJECTION?Arrow

  • Keep IRINOT 40MG INJ 2ML away from the reach of children and pets.
  • Store IRINOT 40MG INJ 2ML at room temperature.

Benefits of IRINOT 40MG/2ML INJECTIONArrow

  • IRINOT 40MG/2ML INJECTION is a chemotherapy medication that plays a crucial role in disrupting the growth and spread of cancer cells within the body. Its mechanism of action involves a transformation process facilitated by liver enzymes, which convert the drug into its active form. This active metabolite then targets and inhibits an enzyme known as Topoisomerase I.
  • Topoisomerase I is essential for DNA replication and repair in cells. By inhibiting this enzyme, IRINOT 40MG/2ML INJECTION interferes with the DNA synthesis process, causing significant damage to the DNA structure of cancer cells. This damage prevents the cells from replicating and multiplying, effectively halting their growth and spread to other parts of the body.
  • This targeted approach makes IRINOT 40MG/2ML INJECTION a valuable tool in cancer treatment, as it specifically aims to disrupt the mechanisms that allow cancer cells to thrive and proliferate. The drug's effectiveness relies on its ability to selectively target and damage the DNA of cancer cells while minimizing harm to healthy cells, although some side effects may still occur. It is typically used as part of a comprehensive cancer treatment plan, often in combination with other chemotherapy drugs or therapies, to achieve the best possible outcome for the patient.

How to use IRINOT 40MG/2ML INJECTIONArrow

  • Always use IRINOT 40MG/2ML INJECTION exactly as your doctor prescribes. This medication will be administered directly into your vein by a qualified healthcare professional in a clinical setting. It is crucial that you do not attempt to self-administer this injection. Prior to starting treatment with IRINOT 40MG/2ML INJECTION, your doctor will likely recommend a DNA test to help determine the most appropriate dosage for you.
  • The correct dosage and duration of treatment with IRINOT 40MG/2ML INJECTION will be determined by your physician based on several factors, including your age, body weight, and the specific characteristics and severity of your disease condition. It is essential to follow your doctor's instructions precisely regarding the timing and frequency of your injections.
  • If you have any questions or concerns about how IRINOT 40MG/2ML INJECTION is administered or about your prescribed dosage, do not hesitate to ask your doctor or nurse for clarification. They can provide you with detailed information and address any worries you may have. Remember, proper administration and adherence to your doctor's instructions are vital for the effectiveness of the treatment.

References

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Accord Healthcare Limited, Electronic Medicines Compendium (EMC)

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Pharmacia & Upjohn Co, US Food & Drug Administration

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Ratings & Review

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Reviewed on 08-01-2024

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Geniune medicines available at good discounts

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Reviewed on 17-07-2023

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Marketer / Manufacturer Details

KHANDELWAL LABORATORIES PRIVATE LIMITED

Country of Origin -

India

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IRINOT 40MG/2ML INJECTION

IRINOT 40MG/2ML INJECTION

MRP

₹

1808.44

₹442

75.56 % OFF

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Disclaimer

Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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