IRINOZEE 40 INJECTION
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IRINOZEE 40 INJECTION
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IRINOZEE 40 INJECTION

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IRINOZEE 40 INJECTION

By ZEE LABORATORIES LTD

MRP

2500

₹550

78 % OFF

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Product DetailsArrow

About IRINOZEE 40 INJECTION

  • IRINOZEE 40 INJECTION belongs to a class of medications known as anti-cancer medicines or cytostatics. It contains the active ingredient Irinotecan hydrochloride trihydrate and is used to treat advanced colon and rectal cancer in adults. It can be prescribed on its own or in combination with other chemotherapy drugs. Colorectal cancer is more common in people over 50 and can be caused by genetic and environmental factors. IRINOZEE 40 INJECTION works by interfering with the growth of cancer cells, eventually destroying them. It is administered via intravenous infusion under the supervision of a healthcare professional.
  • The most common side effects associated with this medication are myelosuppression (bone marrow suppression, which leads to low red blood cell, white blood cell, and platelet counts) and diarrhea. Other common side effects of IRINOZEE 40 INJECTION include nausea, vomiting, abdominal pain, constipation, anemia, pain, fatigue, fever, infections (including sepsis), abnormal bilirubin levels, hair loss, and weight loss. If these side effects become bothersome or persist, inform your doctor. You should also notify your doctor if you have chronic inflammatory bowel disease or a bowel obstruction, or if you have recently received any live vaccines. Careful monitoring and management of side effects are essential during treatment with this medication.
  • Before starting treatment with IRINOZEE 40 INJECTION, tell your doctor if you are allergic to Irinotecan or any of the other ingredients in the injection. You should also inform your doctor about any pre-existing medical conditions, such as liver problems or jaundice, kidney and heart problems, asthma, high blood pressure or high cholesterol, or severe diarrhea. It's also important to inform your healthcare provider if you smoke or have ever received radiation therapy. Let your doctor know about all the medicines, herbs, and supplements you are taking to avoid potential interactions. To prevent pregnancy, both men and women should use effective contraception during treatment. Your doctor will regularly perform blood tests before and during treatment to monitor the effects of IRINOZEE 40 INJECTION on your blood counts and blood chemistry. Staying hydrated and following dietary recommendations can help manage some side effects.

Uses of IRINOZEE 40 INJECTION

  • Management of metastatic cancer affecting the colon and rectum (large intestine).

Side Effects of IRINOZEE 40 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects include early and late diarrhea, allergic reactions, kidney impairment, lung problems, and low levels of RBC, WBC, and platelets in the blood. Common side effects include nausea, vomiting, abdominal pain, constipation, diarrhea, anemia, pain, fatigue, fever, infections including sepsis, abnormal bilirubin levels, hair loss, and weight loss.

  • Early and late diarrhea
  • Allergic reactions
  • Kidney impairment
  • Lung problems
  • Low levels of RBC, WBC, and platelets in the blood
  • Nausea, vomiting, abdominal pain
  • Constipation
  • Diarrhea
  • Anemia
  • Pain
  • Fatigue
  • Fever, infections including sepsis
  • Abnormal bilirubin levels
  • Hair loss
  • Weight loss

Safety Advice for IRINOZEE 40 INJECTIONArrow

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Pregnancy

UNSAFE

IRINOZEE 40 INJECTION is unsafe during pregnancy as it may harm the developing baby. Women with potential childbearing use effective contraceptives during and after six months after treatment.

Dosage of IRINOZEE 40 INJECTIONArrow

  • Always adhere to your doctor's instructions for IRINOZEE 40 INJECTION administration. This medication is administered intravenously by a trained healthcare professional. Do not attempt to self-administer this injection.
  • Before commencing treatment with IRINOZEE 40 INJECTION, your physician will likely recommend a DNA test. This test helps determine if you are more likely to experience certain side effects and allows your doctor to adjust your dosage accordingly.
  • The dosage of IRINOZEE 40 INJECTION is carefully determined by your physician, taking into account several factors including your age, body weight, and the specific characteristics of your disease condition. The duration of treatment will also be decided by your physician based on your response to the medication and other individual factors.
  • It's crucial to communicate openly with your healthcare team about any concerns or side effects you experience during treatment. They can provide guidance and adjust your treatment plan as needed to ensure the best possible outcome.

How to store IRINOZEE 40 INJECTION?Arrow

  • Keep IRINOZEE 40MG INJ 2ML away from the reach of children and pets.
  • Store IRINOZEE 40MG INJ 2ML at room temperature.

Benefits of IRINOZEE 40 INJECTIONArrow

  • IRINOZEE 40 INJECTION is a chemotherapy medication that targets rapidly dividing cells, a hallmark of cancer. Once administered, the injection undergoes a transformation within the body, specifically within the liver, where enzymes convert it into its active form. This active metabolite is the key player in disrupting the cancer cell's machinery.
  • The primary mechanism of action involves inhibiting an enzyme called Topoisomerase I. Topoisomerase I is crucial for DNA replication and repair. It works by temporarily cutting and resealing DNA strands to relieve the stress caused by DNA winding and unwinding during cell division and DNA replication. By blocking Topoisomerase I, IRINOZEE 40 INJECTION effectively interferes with these essential processes.
  • When Topoisomerase I is inhibited, the DNA strands cannot be properly managed, leading to DNA damage. This damage prevents the cancer cells from replicating their DNA accurately and undergoing normal cell division. As a result, the cancer cells are unable to grow and spread, ultimately contributing to the treatment of the cancer. This targeted approach minimizes harm to healthy cells while maximizing the impact on cancerous cells.

How to use IRINOZEE 40 INJECTIONArrow

  • Always take IRINOZEE 40 INJECTION exactly as your doctor prescribes. This medication is administered directly into your vein by a trained healthcare professional. It is crucial that you do not attempt to self-administer this injection. Your physician will likely recommend a DNA test prior to starting treatment with IRINOZEE 40 INJECTION to help determine the most appropriate dosage for you.
  • The dosage and duration of treatment with IRINOZEE 40 INJECTION will be determined by your physician based on several factors, including your age, body weight, the specific condition being treated, and your response to the medication. It is important to adhere to the prescribed schedule and dosage to achieve the best possible outcome. If you have any questions or concerns about how IRINOZEE 40 INJECTION is administered or the length of your treatment, please consult with your healthcare provider.
  • Regular monitoring by your doctor is essential while you are receiving IRINOZEE 40 INJECTION to assess its effectiveness and manage any potential side effects. Do not hesitate to report any unusual symptoms or changes in your health to your doctor or nurse.

FAQs

Do you lose your hair with IRINOZEE 40 INJECTION?Arrow

Hair loss can be a possible side effect of using IRINOZEE 40 INJECTION. It is recommended to discuss this potential side effect with your doctor for further information and guidance.

How to prevent diarrhea while taking IRINOZEE 40 INJECTION?Arrow

Drink large amounts of water and rehydration fluids to prevent diarrhea. It is advised to take antidiarrheal medicines, including loperamide.

What should I do if I miss a dose of IRINOZEE 40 INJECTION?Arrow

If you miss a capsule dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose of IRINOZEE 40 INJECTION.

Is there any interaction of IRINOZEE 40 INJECTION with other drugs?Arrow

There is no known interaction of IRINOZEE 40 INJECTION with other drugs.

What precautions should I take while taking IRINOZEE 40 INJECTION?Arrow

This injection should be taken cautiously in patients with kidney disease or who have undergone dialysis. Diarrhea is the first sign of Irinozee 40mg Injection. It may be serious if diarrhea starts more than 24 hours after administration of this medication. It should be treated immediately and kept under close supervision. If left untreated, it could lead to dehydration and serious chemical imbalances, which can be life-threatening. Try to avoid laxatives and stool softeners while taking Irinozee 40mg Injection. Drink large amounts of water and rehydration fluids immediately. Take antidiarrheal treatment like loperamide. Notify your doctor if you experience any serious side effects. Contact your doctor for more information. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose.

What is IRINOZEE 40 INJECTION made of?Arrow

IRINOTECAN is the molecule/combination used for making IRINOZEE 40 INJECTION.

For which ailments/diseases/conditions is IRINOZEE 40 INJECTION prescribed?Arrow

IRINOZEE 40 INJECTION is used in Oncology.

References

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Accord Healthcare Limited, Electronic Medicines Compendium (EMC)

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Pharmacia & Upjohn Co, US Food & Drug Administration

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Reviewed on 23-11-2022

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Marketer / Manufacturer Details

ZEE LABORATORIES LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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