IRINOTEL 40MG/2ML INJECTION
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IRINOTEL 40MG/2ML INJECTION
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IRINOTEL 40MG/2ML INJECTION

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IRINOTEL 40MG/2ML INJECTION

By FRESENIUS KABI INDIA PVT LTD

MRP

519.12

₹441.25

15 % OFF

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Product DetailsArrow

About IRINOTEL 40MG/2ML INJECTION

  • IRINOTEL 40MG/2ML INJECTION belongs to a class of medications known as anti-cancer medicines or cytostatics. Its active ingredient is Irinotecan hydrochloride trihydrate. It is indicated for the treatment of advanced colon and rectal cancer in adult patients, either alone or in conjunction with other chemotherapy drugs. Colorectal cancer is more common among individuals over 50 years old, with genetic predispositions and environmental factors significantly contributing to its development. This medication works by interfering with the growth and spread of cancer cells in the body. Regular monitoring and adherence to the prescribed treatment plan are essential for managing this condition effectively.
  • The most frequently observed side effects associated with IRINOTEL 40MG/2ML INJECTION are myelosuppression (which can result in reduced levels of red blood cells, white blood cells, and platelets) and diarrhea. Other common side effects include nausea, vomiting, abdominal pain, constipation, anemia, general pain, fatigue, fever, infections (including sepsis), abnormal bilirubin levels, hair loss, and weight loss. It's important to inform your doctor if these side effects become bothersome or persist. Managing these side effects often involves supportive care and may require adjustments to the treatment regimen. Prompt communication with your healthcare provider is crucial for addressing any concerns or adverse reactions.
  • Before starting treatment with IRINOTEL 40MG/2ML INJECTION, it's important to inform your physician about any allergies you may have, particularly to Irinotecan or any of the other ingredients in the injection. Disclose any pre-existing medical conditions, such as liver problems or jaundice, kidney or heart issues, asthma, high blood pressure, high cholesterol, or severe diarrhea. Also, inform your healthcare provider if you are a smoker or have a history of radiation therapy. Discuss all medications, herbal remedies, and supplements you are currently taking to avoid potential drug interactions. Both male and female patients should use effective contraception during treatment to prevent pregnancy. Your physician will conduct regular blood tests before and during treatment to monitor the effects of the medicine on your blood counts and overall blood chemistry, ensuring your safety and the effectiveness of the treatment.

Uses of IRINOTEL 40MG/2ML INJECTION

  • Treatment of metastatic cancer of the colon and rectum (large intestine). This involves addressing cancer that has spread from its original location to other parts of the body.

Side Effects of IRINOTEL 40MG/2ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Early and late diarrhea
  • Allergic reactions
  • Kidney impairment
  • Lung problems
  • Low levels of RBC, WBC, and platelets in the blood
  • Nausea, vomiting, abdominal pain
  • Constipation
  • Diarrhea
  • Anemia
  • Pain
  • Fatigue
  • Fever, infections including sepsis
  • Abnormal bilirubin levels
  • Hair loss
  • Weight loss

Safety Advice for IRINOTEL 40MG/2ML INJECTIONArrow

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Pregnancy

UNSAFE

IRINOTEL 40MG/2ML INJECTION is unsafe to use during pregnancy as it may harm the developing baby. Women who have potential childbearing use effective contraceptives during and after 6 months after treatment.

Dosage of IRINOTEL 40MG/2ML INJECTIONArrow

  • Administer IRINOTEL 40MG/2ML INJECTION exactly as prescribed by your healthcare provider. This medication is administered intravenously, meaning it is injected directly into your vein by a trained healthcare professional. It is crucial that you do not attempt to self-administer this injection.
  • Prior to starting treatment with IRINOTEL 40MG/2ML INJECTION, your physician will likely recommend a DNA test. This test helps determine if your body processes the medication in a typical way and can help avoid some side effects. Your doctor will use the results to personalize your treatment plan.
  • The dosage of IRINOTEL 40MG/2ML INJECTION is carefully calculated and individualized based on several factors. These factors include your age, body size (height and weight), and the specific nature and severity of your medical condition. Your doctor will determine the most appropriate dose for you.
  • During your treatment, your healthcare team will monitor your response to IRINOTEL 40MG/2ML INJECTION. Based on your body's reaction and any side effects you experience, your physician may adjust your dosage. It is important to communicate openly with your doctor about any changes or concerns you have during treatment.

How to store IRINOTEL 40MG/2ML INJECTION?Arrow

  • Keep IRINOTEL 40MG INJ 2ML away from the reach of children and pets.
  • Store IRINOTEL 40MG INJ 2ML at room temperature.

Benefits of IRINOTEL 40MG/2ML INJECTIONArrow

  • IRINOTEL 40MG/2ML INJECTION is a chemotherapy medication that plays a crucial role in disrupting the growth and spread of cancer cells within the body. Its mechanism of action relies on a sophisticated process involving the liver and a key enzyme known as Topoisomerase I. Once administered, the injection undergoes metabolic conversion within the liver, transforming it into its active metabolite form. This active form then specifically targets and inhibits the Topoisomerase I enzyme, which is essential for DNA replication and repair in rapidly dividing cells, such as cancer cells.
  • By inhibiting Topoisomerase I, IRINOTEL 40MG/2ML INJECTION effectively interferes with the DNA synthesis and replication processes of cancer cells. This interference leads to DNA damage, making it impossible for cancer cells to properly divide and multiply. As a result, the uncontrolled growth characteristic of cancer is significantly slowed down, and the spread of cancerous cells to other parts of the body is hindered. This targeted action makes it a valuable tool in cancer treatment regimens.
  • In essence, IRINOTEL 40MG/2ML INJECTION strategically exploits the vulnerabilities of cancer cells by disrupting their DNA processes. The drug's ability to precisely target and inhibit Topoisomerase I makes it effective in controlling cancer growth and preventing its proliferation. It's a vital component in combating various types of cancers and improving patient outcomes.

How to use IRINOTEL 40MG/2ML INJECTIONArrow

  • Administer IRINOTEL 40MG/2ML INJECTION exactly as prescribed by your healthcare provider. This medication is administered intravenously, meaning it is injected directly into your vein by a trained healthcare professional in a clinical setting. It is crucial that you do not attempt to self-administer this medication.
  • Before you begin treatment with IRINOTEL 40MG/2ML INJECTION, your physician will likely recommend a DNA test. This test helps to determine if your body processes the medication in a way that minimizes potential side effects. The results of this test will help your doctor adjust your dosage appropriately.
  • The dosage of IRINOTEL 40MG/2ML INJECTION is carefully determined by your physician and is dependent on several factors, including your age, body size (height and weight), and specific medical condition, as well as how your body responds to treatment. It's important to follow your doctor's specific instructions regarding dosage and frequency of administration. Always consult with your healthcare provider if you have any concerns or questions about your treatment plan.

FAQs

Do you always lose your hair with IRINOTEL 40MG/2ML INJECTION?Arrow

Hair loss is common with IRINOTEL 40MG/2ML INJECTION. It usually starts 3-4 weeks after the first dose of this medication.

Does IRINOTEL 40MG/2ML INJECTION cause liver damage?Arrow

IRINOTEL 40MG/2ML INJECTION may cause liver impairment or damage. Inform your physician before starting treatment if you have liver disease or jaundice.

What happens if IRINOTEL 40MG/2ML INJECTION is taken in more than recommended dose?Arrow

If IRINOTEL 40MG/2ML INJECTION is taken in more than the recommended doses, it can cause severe blood disorders and diarrhea.

Which is the best area to administer IRINOTEL 40MG/2ML INJECTION?Arrow

IRINOTEL 40MG/2ML INJECTION will be administered into the vein under strict medical supervision. Do not self-administer.

How to prevent diarrhea while taking IRINOTEL 40MG/2ML INJECTION?Arrow

Drink large amounts of water and rehydration fluids to prevent diarrhea. It is advised to take antidiarrheal medicines, including loperamide.

Does IRINOTEL 40MG/2ML INJECTION interact with other drugs?Arrow

There is no known interaction of IRINOTEL 40MG/2ML INJECTION with other drugs.

What is the first sign of IRINOTEL 40MG/2ML INJECTION?Arrow

Diarrhea is the first sign of IRINOTEL 40MG/2ML INJECTION. It may be serious if diarrhea starts more than 24 hours after administration of this medication. It should be treated immediately and kept under close supervision. If left untreated, it could lead to dehydration and serious chemical imbalances, which can be life-threatening. Try to avoid laxatives and stool softeners while taking this medicine. Drink large amounts of water and rehydration fluids immediately. Take antidiarrheal treatment like loperamide.

What molecule/combination is used for making IRINOTEL 40MG/2ML INJECTION?Arrow

IRINOTECAN is the molecule/combination used for making IRINOTEL 40MG/2ML INJECTION.

For what conditions is IRINOTEL 40MG/2ML INJECTION prescribed?Arrow

IRINOTEL 40MG/2ML INJECTION is used in Oncology.

Is IRINOTEL 40MG/2ML INJECTION a chemotherapy drug?Arrow

Yes, IRINOTEL 40MG/2ML INJECTION is a chemotherapy drug used to treat cancer.

References

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Accord Healthcare Limited, Electronic Medicines Compendium (EMC)

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Pharmacia & Upjohn Co, US Food & Drug Administration

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Marketer / Manufacturer Details

FRESENIUS KABI INDIA PVT LTD

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₹441.25

15 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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